Tumour immunology and immunotherapy

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  • เผยแพร่เมื่อ 24 ธ.ค. 2024

ความคิดเห็น • 434

  • @Inspiration.U
    @Inspiration.U 2 ปีที่แล้ว +113

    As a Medical practioneer..I can justify the amount of knowledge provided in such a easy and professional way....I will highly recommend it to my colleague's

    • @noname8354
      @noname8354 2 ปีที่แล้ว +2

      I'm still a bio undergrad but some of the best literature I've ever read were from literature reviews in Nature. They're long af but extremely easy to understand a lot of the time, even for people without a lot of prior knowledge about these things

    • @saddamalgafsi6721
      @saddamalgafsi6721 ปีที่แล้ว

      it's incredible how well it's animated and how concise and instructful it is!

    • @zzagriff
      @zzagriff ปีที่แล้ว

      @@noname8354Narrative reviews are very good for basic sciences

  • @DrBLOOD1995
    @DrBLOOD1995 6 ปีที่แล้ว +1051

    If all medical books were replaced by animations like these, medical studies would be less boring, more easy to understand and remember and more attractive.

    • @rm9308
      @rm9308 6 ปีที่แล้ว +98

      You still need books.

    • @Azuwww
      @Azuwww 5 ปีที่แล้ว +10

      @tractor Wrong.

    • @DrEru
      @DrEru 5 ปีที่แล้ว +8

      @tractor pathology: excuse me wtf!

    • @MrSidney9
      @MrSidney9 5 ปีที่แล้ว +36

      Remember, medical doctors aren't scientists. Research on cancer and possible treatments are done by biochemists, oncologists...human biology/biochemistry is really hard. Harder than any other disciplines.

    • @erickdanielperez9463
      @erickdanielperez9463 5 ปีที่แล้ว +20

      The problem is that the animations are limited; Many times what is written in medical books, comes from the direct experience of those who have seen the complexities of tissues. In half paragraph describe more than this animation in 5 minutes, can not do.

  • @Flop1000
    @Flop1000 5 ปีที่แล้ว +117

    I’m a doctoral student in Molecular Biology, and these animations are beautiful! I’ll be sure to use these with my classes!

  • @dr.maryamabid9371
    @dr.maryamabid9371 ปีที่แล้ว +17

    As a practicing oncologist I must say this is by far the most easy and great animation on Immunotherapy I have watched.

  • @mikaelfalk6720
    @mikaelfalk6720 8 ปีที่แล้ว +313

    Awesome video, I really wish there were more animated videos like this one, that they were longer and more in-depth.

  • @remembranceproduction4395
    @remembranceproduction4395 8 ปีที่แล้ว +78

    keep looking... keep finding... don't give up hope.

  • @SnrKagemusha
    @SnrKagemusha 9 ปีที่แล้ว +310

    Fascinating video.
    My only comment: someone should actually make that cancer-fighting version of "Space Invaders".

    • @prantokumarsarker9460
      @prantokumarsarker9460 5 ปีที่แล้ว +2

      😅😅

    • @crashjohnny_
      @crashjohnny_ 5 ปีที่แล้ว

      Exactly! 😂

    • @mrniceguy4277
      @mrniceguy4277 5 ปีที่แล้ว +4

      I have a game called "Fungalinvaders" that already goes into that direction (as the name suggests, you fight fungi). But it's a shitty game

    • @bradebronson8835
      @bradebronson8835 5 ปีที่แล้ว

      Dr. Mario

    • @vladbcom
      @vladbcom 5 ปีที่แล้ว

      Good idea, I'll get on it

  • @hashhoomy
    @hashhoomy 6 ปีที่แล้ว +28

    سبحانك ربي ما أبدعك، وعلم الإنسان ما لم يعلم.

    • @erenyalcn9393
      @erenyalcn9393 5 ปีที่แล้ว +2

      Nice bomb plans

    • @darrenanimatic9675
      @darrenanimatic9675 5 ปีที่แล้ว +1

      What??? I'm no Arabic, but...
      🔠🔡🔢🔤🅰️🆎🅱️🆑🅿️🆔🅱️🆑🆎🅾️🅰️🈁🈂️🈷️🈶🈯️🉐🈹🈚️🈲🉑🈸🈴🈳㊗️㊙️🈺🈵

    • @MrZer000
      @MrZer000 5 ปีที่แล้ว

      ignorant pricks

    • @bity-bite
      @bity-bite 5 ปีที่แล้ว +5

      @@erenyalcn9393 Haha. It is funny how fake media news fucked up your brain, what a racist. Do we need to talk about how is your religion just about sex "Christianity" (If you were a Christian), adultery, gay etc... Pfft

    • @mary-cq2sz
      @mary-cq2sz 4 ปีที่แล้ว +1

      سبحان الخالق ما أروع خلقه!!!

  • @carlosfernandocastanedaola1612
    @carlosfernandocastanedaola1612 10 หลายเดือนก่อน +1

    Thank you so much Nature video. Greetings from Molecular Biology, enviromental and Cancer Research Group (BIMAC) and Bioengineering graduate studies at Universidad del Cauca, Colombia.

  • @lotfihamoudi3174
    @lotfihamoudi3174 5 ปีที่แล้ว +14

    Thanks for the video and we pray to God to heal all the sick

  • @anactualmango_
    @anactualmango_ 2 ปีที่แล้ว +5

    i cant believe im going to be working with postdocs on cancer research and therapeutics for my research lab placement in my final year of college as a molecular bioscience student! this was really helpful thank you

  • @ufatemav4509
    @ufatemav4509 2 ปีที่แล้ว +8

    Imagine creating a video game for middle/high school students like the one shown in the video. Science integration in animations and games is truly an effective way to boost ones understanding of the concept!

  • @donross7820
    @donross7820 2 ปีที่แล้ว +1

    No one ever talks about induced Innate Immunity and the interactions of Dendritic Cells, NK Cells, and Macrocytes. We all catch 1 million cancers every day but the cell receptors of these detect them and destroy the malignant cell. So eat your fruits and vegetables, exercise, maintain a slim weight, and avoid excessive alcohol! BTW, I love to create this type animation as a hobby and this one is especially beautiful. And Parham The Immune System is a wonderful book. When I went to med school I was taught things like "somehow muscles contract" and "somehow infections are controlled" but now it seems every step in every signaling pathway has been figured out. It is incredible (and so exciting) how much is now known about the immune system and all the new practical applications of that knowledge!

  • @ahmadalmasri826
    @ahmadalmasri826 5 ปีที่แล้ว +6

    This is definitely the best video I watched in all my medicine studies.

  • @hanniballi
    @hanniballi ปีที่แล้ว

    I think there is a mislabeled point in video at 3:50. It should be labeled in regulatory T cell not Helper T cell.

  • @getoutofmyway9025
    @getoutofmyway9025 6 ปีที่แล้ว +22

    Nk cell is my spirit animal

  • @eleanorsheekey9573
    @eleanorsheekey9573 6 ปีที่แล้ว +15

    This video is EPIC! Makes much sense of the long list of names and roles of the non-transformed tumour associated cells!

  • @data790
    @data790 6 ปีที่แล้ว +22

    Life saver. I have to give a trial lecture on lung cancer and the immune system as part of my PhD defence. This video helped me understand all therapies thereafter. Thank you. Please accept one of my papers for publishing :)

    • @MegaSantiago20
      @MegaSantiago20 ปีที่แล้ว +1

      How did it go? And a very big thanks for your research on those subjects!

    • @data790
      @data790 ปีที่แล้ว +1

      @@MegaSantiago20 it went super well - if I remember. Was a fun day. Passed so all good

    • @MegaSantiago20
      @MegaSantiago20 ปีที่แล้ว

      @@data790 Awesome!

  • @Lets_Talk13
    @Lets_Talk13 7 หลายเดือนก่อน

    After the third chemotherapy session, he stopped eating due to severe mouth ulcers and was hospitalized again. Though stable initially, his condition worsened, leading to organ failure. Despite being on life support, he passed away the following day. I share this to urge others in similar situations to be extremely vigilant.

  • @Mariiiam
    @Mariiiam 2 ปีที่แล้ว +19

    Most interesting topic ever. I wish we could someday replace the chemotherapy/radiation totally with modified immunotherapy.

    • @WhosWhointheZoo123
      @WhosWhointheZoo123 ปีที่แล้ว +1

      Chemo drugs come from the Perrywinkle/Vinca plant... God gave us everything we need in the form of plants and weeds.

  • @KenJackson_US
    @KenJackson_US 5 ปีที่แล้ว +14

    Remember, NK cells and their ability to sense stress-associated molecules came about by chance, as did helper T cells, dendritic cells, cytotoxic T cells, coreceptors, perforin and granzymes. Their obvious design wasn't designed. Never mind the effectively infinite permutations of a string of amino acids that had to be searched to find functional proteins.

    • @billmorehouse2324
      @billmorehouse2324 2 ปีที่แล้ว +1

      Hare Kṛṣṇa
      Toward the scientific case for Intelligent Design (in Biology), a presentation from Discovery Institute Founder, Professor Phillip E. Johnson
      th-cam.com/video/FDbSNKdTyZs/w-d-xo.html
      Hare Rāma

    • @brightobi5361
      @brightobi5361 2 ปีที่แล้ว +1

      Came about by chance?
      Balderdash!!!

    • @KenJackson_US
      @KenJackson_US 2 ปีที่แล้ว +1

      Yeah, it's pretty far fetched, @@brightobi5361.

    • @Jesus_Resurrection_and_Life
      @Jesus_Resurrection_and_Life 2 ปีที่แล้ว

      I don’t believe Creationist Believers in Intelligent Design would agree 🫶🏼 🌸 🫶🏼 🌸 🫶🏼

    • @KenJackson_US
      @KenJackson_US 2 ปีที่แล้ว

      Very good, @@Jesus_Resurrection_and_Life.

  • @theclassifiedmedia-j6d
    @theclassifiedmedia-j6d ปีที่แล้ว

    As medical students this great technology that our ancestors have not seen it before

  • @remembranceproduction4395
    @remembranceproduction4395 8 ปีที่แล้ว +39

    Each individual's body reaction to medicine and therapy are different. a patient has to try and find the right medicine or combination for the body.

    • @justindie7543
      @justindie7543 6 ปีที่แล้ว +8

      it's not your body per se. It's which genes you happen to possess and how those genes are expressed. More DNA screening and more specifically single cell RNA seq. should be used to compare treatment options before anyone spends their life savings on it.

    • @drekson23
      @drekson23 5 ปีที่แล้ว

      So how about those cancer survivors?

    • @yasenkalchev7664
      @yasenkalchev7664 4 ปีที่แล้ว

      @@drekson23 good point, the best point actually !

    • @yasenkalchev7664
      @yasenkalchev7664 4 ปีที่แล้ว

      @@drekson23 Good point, the best point actually !

    • @samvrit
      @samvrit 4 ปีที่แล้ว

      @@drekson23 they survive because of either surgery or medical assistance. The body recovers on its own OR the tumor is removed surgically. There has not been a cure for cancer, yet.

  • @mxwsn
    @mxwsn 9 ปีที่แล้ว +16

    Love that space invaders animation

  • @DoubleGauss
    @DoubleGauss 6 ปีที่แล้ว +6

    Fantastic graphics ! Great job Nucleus Medical Media.

  • @jessicamcdonald3545
    @jessicamcdonald3545 8 ปีที่แล้ว +21

    This animation is so cool

  • @ayaafifi872
    @ayaafifi872 4 ปีที่แล้ว +13

    I love the immunity so much ❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️❤️

  • @Perpetualteachings
    @Perpetualteachings 6 ปีที่แล้ว +6

    It brought me more closer towards science.Please keep it up

  • @johnhome5872
    @johnhome5872 3 ปีที่แล้ว +1

    Get rid of background noise!

  • @jiangyongguo
    @jiangyongguo 10 หลายเดือนก่อน

    Hello my friend, may I ask if your company needs anti-cancer drugs-
    (Including formula, raw materials, semi-finished products)? I am from China.

  • @starinitalian
    @starinitalian 6 ปีที่แล้ว +25

    !!! *PLEASE ADD THE KOREAN SUBTITLES I MADE* !!! (There are parts that are translated liberally)

  • @Enran-g9q
    @Enran-g9q 3 หลายเดือนก่อน

    Can I use a short clip of this for our project promotion video? The clip would be used to illustrate how skin tumor grows and the video is for iGem competition. Thank you very much for considering our request. We look forward to hearing from you.

  • @savitaraina7928
    @savitaraina7928 ปีที่แล้ว

    What if nk2 cells increase the reverse case

  • @resulhackr5527
    @resulhackr5527 4 ปีที่แล้ว +1

    The best animation that I have ever seen.Good job

  • @ksbalaji1287
    @ksbalaji1287 6 ปีที่แล้ว +6

    Thank you for this very carefully and clearly thought out video.

  • @rubbish9231
    @rubbish9231 2 ปีที่แล้ว

    As a smoker I needed to know this. Thanks

  • @SpartaMarz94
    @SpartaMarz94 7 ปีที่แล้ว +7

    How is the immune response from the macrophages against the tumoral cells?

    • @SukacitaYeremia
      @SukacitaYeremia 6 ปีที่แล้ว

      @bietoff0728 Wth.. Is this spam?

    • @Sn1per9CZE
      @Sn1per9CZE 6 ปีที่แล้ว

      @bietoff0728 Another mindwashing "expert"

    • @Sn1per9CZE
      @Sn1per9CZE 6 ปีที่แล้ว +3

      @bietoff0728 Enough to know that homeopatics and herbal treatments for diseases like cancer are a dangerous game, because of which people die.

  • @leot8433
    @leot8433 3 ปีที่แล้ว

    And after five year also treatment has same status. No progress while we fight for COVID but cancer patients die of lack of available treatment. Specially patients with ALK Negative and PDL1 Negative.

  • @kitography6803
    @kitography6803 ปีที่แล้ว

    Is there a way to get rid of the background music? Or another version without it?

  • @nooninst
    @nooninst 2 ปีที่แล้ว

    what is the microscope used in this video ????

  • @spiridongeorgakis3860
    @spiridongeorgakis3860 3 ปีที่แล้ว

    nice video but some of the information provided are missleading/wrong
    IL-2 and IFN-a are not efficient therapeutic targets because:
    1) IL-2 will also promote the expansion of Tregs leading to immunosuppresion and cancer progression
    2) IFN-a could promote lupus-like syptoms

  • @nimrajavednimrajaved5731
    @nimrajavednimrajaved5731 5 ปีที่แล้ว +6

    Why the hell is music sooo loud i can't hear the lecture man

  • @torreyance2468
    @torreyance2468 6 ปีที่แล้ว +10

    thank you for this video. my genetics teacher made things more complicated than they have to be. this video makes visualizing what happens easier.

  • @nazifekonar2240
    @nazifekonar2240 5 ปีที่แล้ว +2

    Great video,Great explanation!

  • @noemijesaminem.duenas818
    @noemijesaminem.duenas818 3 ปีที่แล้ว +12

    This channel deserves more subscribers because of its creativity and hardworkship on this fascinating animation video
    Well done😊😊😊

  • @rellideveraux386
    @rellideveraux386 3 ปีที่แล้ว +1

    Really helped me understand how the treatment helps. Thank you.

  • @serogolemogole2685
    @serogolemogole2685 4 ปีที่แล้ว +1

    I'm not in health science but I'm enjoying this insightful presentation tremendously

  • @professord1522
    @professord1522 4 ปีที่แล้ว +1

    I really liked this video. PLEASE make one describing oncolytic immunotherapies such as T-VEC!

  • @Banker_blessed1111
    @Banker_blessed1111 2 ปีที่แล้ว

    If animation replace all written information then human being will reach to next level because then normal person can understand so much and prohibit any disease by knowing it's symptoms and can seek best medical care

  • @onyekachiobasi864
    @onyekachiobasi864 3 ปีที่แล้ว

    Animations are purely effective.

  • @blancosanmartin
    @blancosanmartin 2 ปีที่แล้ว

    One of the best videos about inmune system our there.

  • @NOUSSAROM
    @NOUSSAROM 2 ปีที่แล้ว +1

    Amazing video. Spending all efforts and great technology to make this video clear and more more easy to understand. Thank you

  • @mrsdiggory3211
    @mrsdiggory3211 3 ปีที่แล้ว +1

    Amazinggggg! Thank you for the amazing and concise and clear and fun animation

  • @vincenttelfer4206
    @vincenttelfer4206 2 ปีที่แล้ว

    possible cutting off the afferent supply of blood to tumor or rogue vein

  • @ganbatgantulga3833
    @ganbatgantulga3833 2 ปีที่แล้ว

    CD8 T cell's mediated cytotoxicity scene was amazing

  • @susanahernandez6893
    @susanahernandez6893 7 หลายเดือนก่อน

    I really loved the video; and in addition, some other mechanisms of immune evasion by tomours would be the loose of the MHC 1 expression so that cell can not be detected by the lymphocyte T, but that can be helpulf for the cells NK to detected tose cells without MHC1. I'm surprised of how tomours can do the same mechanism as the Immune-privileged tissues, so they can decreased or stop the inmune response. And the inmunotherapy is like a way to potencial the functions of the T cells, so they can continue their work.

  • @tmujir955
    @tmujir955 2 ปีที่แล้ว

    I was amazed by the quality of the animation and the concept of immunoediting.

  • @pharmacop
    @pharmacop 2 ปีที่แล้ว

    Beautiful presentation. Thank you.

  • @mgtowstanleyzoltanov9808
    @mgtowstanleyzoltanov9808 4 ปีที่แล้ว +1

    Will this be available to regular humans?

  • @sofyaleyn
    @sofyaleyn 8 ปีที่แล้ว +2

    Can I use this video with Nature Video credentials mention for teaching?

  • @praptobakrie5861
    @praptobakrie5861 2 ปีที่แล้ว

    Immunology is very important..

  • @normanspurgeon5324
    @normanspurgeon5324 5 ปีที่แล้ว +2

    Thank you for the video. Why do we need the imitation music in the background?

  • @jacksonhaw5514
    @jacksonhaw5514 4 ปีที่แล้ว +1

    I am wondering is this the good cells?

  • @Netbook451
    @Netbook451 7 ปีที่แล้ว +2

    This helped a tremendous amount for my presentation. Thank you.

  •  2 ปีที่แล้ว

    Thank you Nature

  • @edgaral
    @edgaral 3 ปีที่แล้ว

    Question is how tumours can use those small PDL connections and such outta nowhere, as if Tumors were intended when they're bad, feels weird to me

  • @banerjeea2
    @banerjeea2 6 ปีที่แล้ว

    Can anyone share the link to the background music? What a fascinating musical score?

  • @darrenmarchant1720
    @darrenmarchant1720 5 ปีที่แล้ว

    it may be that using tatooing to administer site specific medicine in the case of skin related issues such as melanoma will be found to reduce the effect of such medication on other parts of the body. another possible treatment for melanoma may be cauterization, which has been used by Arab communities to this day for other issues with some similarity to acupuncture. very little research is available on Arab medicine at this time.

  • @duocphamtruongtho4462
    @duocphamtruongtho4462 3 ปีที่แล้ว +1

    thank you for this video

  • @WallaceRoseVincent
    @WallaceRoseVincent 5 ปีที่แล้ว

    Animations always make it look so easy.

  • @auroralucrezia8187
    @auroralucrezia8187 หลายเดือนก่อน +2

    Is this how fibroids grow?

  • @PatsyGoGo
    @PatsyGoGo 2 ปีที่แล้ว

    Great video, although background music is too loud for me to fully listen and concentrate to the subject. Especially, when English is not the native language.

  • @roninabil1
    @roninabil1 5 ปีที่แล้ว +1

    Thanks for your clear explanations, Many thanks

  • @Flying.clouds.roots.of.rainbow
    @Flying.clouds.roots.of.rainbow 5 ปีที่แล้ว

    is immuno therophy works on brain tumor..that to pilocytic astrocytoma tumor ..my 5yrs child had that tumor..surgery,radio therophy. .chemotherapy all r failed to cure the disease.

  • @adriancastro87
    @adriancastro87 2 ปีที่แล้ว

    Great video about inmune response

  • @wowalamoiz9489
    @wowalamoiz9489 2 ปีที่แล้ว

    Hehe, here’s a like for the Space Invaders reference. Whoever made this had a sense of humor.

  • @matthewroy7718
    @matthewroy7718 6 ปีที่แล้ว

    THE future of cancer treatments alongside TIL. Keep discovering!

  • @moutazhelal7694
    @moutazhelal7694 4 ปีที่แล้ว

    thank you for a nice video. can I ask how can I make such video. what tools did you use ?

  • @kevinwandago4339
    @kevinwandago4339 3 ปีที่แล้ว

    thanks so much! very helpful

  • @lydiacole1161
    @lydiacole1161 2 ปีที่แล้ว

    Such an amazing video!!! So much better than any textbook I’ve read

  • @rakeshagnihotri598
    @rakeshagnihotri598 4 ปีที่แล้ว

    Sir i have a tumor in my finger though it very small but its very painful i want to know how and where can i go to seek this immunotherepy

  • @remembranceproduction4395
    @remembranceproduction4395 8 ปีที่แล้ว +1

    there is a different type of immunotherapy that. block the cd 47, and uses the macrophages instead of t cell to fight the cancer.

  • @silasenglish
    @silasenglish 7 ปีที่แล้ว +1

    4life Research have been doing their research on this 50 years ago.

  • @aj-uo3uh
    @aj-uo3uh 2 ปีที่แล้ว

    huh, so cd4 stimulates dc to stimulate cd8. I thought dc only represents antigen and that it doesnt need stimulation...

  • @RainAngel111
    @RainAngel111 6 ปีที่แล้ว +9

    Imo immunotherapy, especially the therapies focusing on killer T cells specific to the patients cancer, just may be the silver bullet we've been waiting for in the cure for cancer

    • @FKGZ7
      @FKGZ7 6 ปีที่แล้ว +4

      If we can eliminate or reduce the side effects then probably yes

    • @solidfuel0
      @solidfuel0 6 ปีที่แล้ว +2

      @@FKGZ7 what side effects? I thought it's better than chimo

    • @FKGZ7
      @FKGZ7 6 ปีที่แล้ว +2

      @@solidfuel0 Yes but still it can kills healthy cells and in some cases patients developed an autoimmune response. We need to increase the specificity furthermore.

    • @hephaestus9901
      @hephaestus9901 5 ปีที่แล้ว +2

      @@FKGZ7 there will never be a cure for "cancer" cancer is a wide variety of genetic diseases.There will never be one thing that will cure all forms of cancer

    • @King-Star9402
      @King-Star9402 4 ปีที่แล้ว +1

      I also think the Immune System it is the cure for cancer so what we all have to do is keep boosting the Immune System and stay healthy all the time.

  • @clairepackwood53
    @clairepackwood53 5 ปีที่แล้ว +1

    Totally awesome animation video. Thank you. Can we have more please?

  • @soyeonsoykim
    @soyeonsoykim 3 ปีที่แล้ว

    Fantastic animation!! Thank you

  • @nickkassouf
    @nickkassouf 9 ปีที่แล้ว +5

    Fantastic video here.

  • @rlaaudtjq
    @rlaaudtjq 3 ปีที่แล้ว

    Many thanks for this very informative video

  • @rocc6596
    @rocc6596 6 ปีที่แล้ว

    Does immunotherapy work for every cancer ,

  • @dystopia730
    @dystopia730 4 ปีที่แล้ว +3

    This is great!!

  • @dramirfarhadbahreini6477
    @dramirfarhadbahreini6477 2 ปีที่แล้ว

    Good animation.obstract special liy????? immunology.

  • @remembranceproduction4395
    @remembranceproduction4395 8 ปีที่แล้ว +2

    cd 47 therapy combined with the available immunotherapy can help more and more people with cancer.

  • @jorgevillarroel6046
    @jorgevillarroel6046 5 ปีที่แล้ว +1

    Me encantaría, si pueden traducirlo al español!!!
    Gracias

  • @kingsharma8653
    @kingsharma8653 4 ปีที่แล้ว +1

    Is it mole?

  • @downstg
    @downstg 2 ปีที่แล้ว

    Combining checkpoint inhibitors with different action is a good idea as well.

  • @devarain
    @devarain 2 ปีที่แล้ว

    Me: WHAT THE FUCK HE TALKING ABOUT??
    2:45
    Me: I see, now I understand

  • @thefenerbahcesk4156
    @thefenerbahcesk4156 6 ปีที่แล้ว +2

    So many abbreviations in this vid.

  • @Ded-Ede
    @Ded-Ede 2 ปีที่แล้ว

    I hope and pray.

  • @thamilselvan3176
    @thamilselvan3176 5 ปีที่แล้ว

    Nice animation with clear points