honestly, the more I look into biochemistry the more I feel happy to be alive. It's such an honor to be the intricate machines we are, and even more to be capable of understanding or inner workings. :)
Excellent video Throughout highshcool and during my intro to cell bio course, cofactors were always relegated to being "things that help enzymes". It's nice to be able to see some chemical basis for the reasoning behind this! Thanks sal.
Sometimes breaking down and slowing down to teach something helps out a lot. I was confused the whole time because our PowerPoints were so simple and didn't go into so much detail. next video
Anjelica luna simple? Why are you watching a TH-cam video then? Go to a college lecture for molecular biology if you want complicated biochemistry or how about you read a research paper on enzyme dynamics and mechanisms. This video is plenty complicated for the lay person, why do you feel the need to be rude?
GGyourdead yes my modules were simple. Do you have a problem lol? And I did do all of that. You wouldn’t know because it’s not like I post my everyday life on here. Thanks for your feedback 👋🏼
Hello! I just saw this video and I have been puzzled by co-enzymes for quite some time. ( I am 82 yrs. old) When I look at all discussions of the Kreb's cycle I always get the impression that the co-enzyme NAD is functioning independently without the benefit of an apo-enzyme. Is that so????. Or is the fact that the NAD is just a part of the holoenzyme and that the entire holoenzyme is there at work: is that just understood by everyone else, but me. I would surely appreciate anyone's response to this question. Sincerely, John Mulflur, M.D.
In my textbook it says that coenzymes are organic cofactors derived from water-soluable vitamins. They accept electrons from an enzyme in one metabolic pathway and transfer them to an enzyme in another.
Coenzymes are characterized as labile. For example, HCN is highly labile lending it's proton or hydrogen ion easily. It actually deserves the status as a B vitamin. Papain, the enzyme of papaya carica is activated by HCN.
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honestly, the more I look into biochemistry the more I feel happy to be alive. It's such an honor to be the intricate machines we are, and even more to be capable of understanding or inner workings. :)
Excellent video
Throughout highshcool and during my intro to cell bio course, cofactors were always relegated to being "things that help enzymes". It's nice to be able to see some chemical basis for the reasoning behind this! Thanks sal.
Sometimes breaking down and slowing down to teach something helps out a lot. I was confused the whole time because our PowerPoints were so simple and didn't go into so much detail. next video
Anjelica luna simple? Why are you watching a TH-cam video then? Go to a college lecture for molecular biology if you want complicated biochemistry or how about you read a research paper on enzyme dynamics and mechanisms. This video is plenty complicated for the lay person, why do you feel the need to be rude?
GGyourdead yes my modules were simple. Do you have a problem lol? And I did do all of that. You wouldn’t know because it’s not like I post my everyday life on here. Thanks for your feedback 👋🏼
GGyourdead also I didn’t know my comment was rude lol just stated I was confused the whole time
Hello!
I just saw this video and I have been puzzled by co-enzymes for quite some time. ( I am 82 yrs. old)
When I look at all discussions of the Kreb's cycle I always get the impression that the co-enzyme NAD is functioning independently without the benefit of an apo-enzyme. Is that so????. Or is the fact that the NAD is just a part of the holoenzyme and that the entire holoenzyme is there at work: is that just understood by everyone else, but me.
I would surely appreciate anyone's response to this question.
Sincerely,
John Mulflur, M.D.
I hope you are well!
so helpful. I was stuck and confused, I didn't know the rile of cofactors and what they actually real are. thanks for the clear explanation.
*role* not rile
Brilliant video thank you! 🧬🧬
faites les vidéos en francais aussi svp
I learn more things from ur videos
I wanted to know example of enzyme-cofactor pairs. Eg biotin is the cofactor of pyruvate carboxylase; NAD+ for pyruvate carboxylase
In my textbook it says that coenzymes are organic cofactors derived from water-soluable vitamins. They accept electrons from an enzyme in one metabolic pathway and transfer them to an enzyme in another.
I love that explanation. Thank you.
I love this example!
Thankful for you
7:00 text and line drawings difficult to see with smartphone please increase the contrast
Excellent, as always.
I dn't understand so much confuse .. but ur teaching style is good
so helpful...
I want to know why Khan knows everything😭
really helpful
Distracting electrons so electrons can proceed? 🤔 I’m confused
If the background is white,it'll be very helpful to me.
6 people who disliked the video is probably professors lol this khan guy is so good 👍
Why is biology so wierd? THANKS SAL!
Nice
Can anybody tell the exact binding site of cofactor.. Is it the same active site where cofactor binds?? Or different
if you know it, which enzymes need copper as a coenzyme?
question wrong, copper is not organic, so we talk about a cofactor :) understood
All the B vitamins and only the B vitamins are coenzymes. Other vitamins are cofactors. Vitamin C is a cofactor, not a coenzyme.
Coenzymes are characterized as labile. For example, HCN is highly labile lending it's proton or hydrogen ion easily. It actually deserves the status as a B vitamin. Papain, the enzyme of papaya carica is activated by HCN.
I have a khan academey account
+Swapan Biswas Good!
I didn't understand the magnesium part can anyone explain?
Mg ion attach with O anion
As a result the 2 hands of P become empty . So P is able to react with glucose
can anyone tell me if cofactors are permanent or temporary???
They are temporary they fall of over time or are removed by another enzyme to stop them from carrying out their functions.
I got confused
I'm so done, what the fuck is this. All I see is squiggly lines with random letters and numbers
Don't pick a science major
lmao
his voice so hot tho
Hmm, not the best KA video... I could've done a better job of explaining this - I only came here for one answer and ended up googling it. Just sayin.