Hi Kimberly, you are right. A coenzyme is a cofactor. A loosely bound cofactor is a coenzyme and a tightly bound cofactor is a prosthetic group. Cofactors are non-protein "helper" molecules that can be classified as organic or non organic ( sometimes restricted to inorganic substances only). Organic molecules are either vitamins or made from vitamins like the vitamins B1, B2, B3, B5, B6 and Biotin. Inorganic cofactors are usually metal ions like Mg2+ Extra terminology: Holoenzyme - enzyme + cofactor (the whole complex) apoenzyme - enzyme that is missing its cofactor Hope this helps!
Aren't co-enzymes a type of co-factor? In this video it implies co-factors and co-enzymes are two different things. Shouldn't the correct classification of co-factors be co-enzymes and metal ions and co-enzymes are then further divided in to co-substrates and prosthetic groups?
Hi. I would just like you to clarify this if you may so please, but isn't coenzyme a cofactor? Aren't cofactors be classified by the tightness of their bind to an enzyme: to be as a coenzyme --a loosely bounded organic cofactor; or a prosthetic group --a tightly bounded (may be organic or inorganic) cofactor? I would greatly appreciate if someone can clear this stuff. Thanks!~
I may be wrong, but I thought that coenzymes are one of two classes of cofactors. That is to say, coenzymes are in fact cofactors, that are not ions (like Mg) but rather prosthetic groups or cosubstrates.
Not necessarily. Prosthetic group could also be a metal ion which is an integrated part of the enzyme; a) hold the enzyme together (to maintain its catalytically active conformation); b), 1. Bind to the enzyme (usually at its active site), and hold the enzyme together; 2. and participates in the catalysis. In both cases (a & b) metal ion is a catalytically essential factor of the enzyme. Enzyme cannot perform without it.
All the B vitamins and only the B vitamins are coenzymes. Other vitamins are cofactors. Vitamin C is a cofactor, not a coenzyme. Coenzymes are characterized as labile. For example, HCN is highly labile lending it's proton or hydrogen ion easily. It actually deserves the status as a B vitamin. Papain, the enzyme of papaya carica is activated by HCN.
Hi Kimberly, you are right. A coenzyme is a cofactor. A loosely bound cofactor is a coenzyme and a tightly bound cofactor is a prosthetic group. Cofactors are non-protein "helper" molecules that can be classified as organic or non organic ( sometimes restricted to inorganic substances only). Organic molecules are either vitamins or made from vitamins like the vitamins B1, B2, B3, B5, B6 and Biotin. Inorganic cofactors are usually metal ions like Mg2+
Extra terminology:
Holoenzyme - enzyme + cofactor (the whole complex)
apoenzyme - enzyme that is missing its cofactor
Hope this helps!
Tq for information
Thank you
Really helpful thanks 😊
I would like to point out that coenzyme is also a cofactor.
S
Exactly
great video, does anyone else think he sounds like Schmit from New Girl
I come here to clear my coenzymes topic, but I am going with clearing 3-4 more topics in it.
Thank you so much. I was so confused before this
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What an easy way to understand. Great job!
Shesh u goood! Thanks!❤
Aren't co-enzymes a type of co-factor? In this video it implies co-factors and co-enzymes are two different things. Shouldn't the correct classification of co-factors be co-enzymes and metal ions and co-enzymes are then further divided in to co-substrates and prosthetic groups?
+Neerodha Edirisinghe Hello ! can you give me your facebook please :)
+YARA ADDAG fucking freak
I guess coenzyme are actually having attached organic molecule to it but cofactor is free as given example Mg
Neerodha Edirisinghe ya
U are great u deserve more views
Thank you
😊
Thanks!
thank you
got any info on how trace minerals build enzymes? like a caesium, thorium, vanadium, gallium, tin, copper, etc?
Thank you very much, I'm glad to have learned this =)
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awesome, you helped me
what are the role of coenzymes in respiration?
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thank you so much
Hi. I would just like you to clarify this if you may so please, but isn't coenzyme a cofactor? Aren't cofactors be classified by the tightness of their bind to an enzyme: to be as a coenzyme --a loosely bounded organic cofactor; or a prosthetic group --a tightly bounded (may be organic or inorganic) cofactor? I would greatly appreciate if someone can clear this stuff. Thanks!~
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super helpful
Tks for the great video and explanations
Great Video
Great
I swear all co-factors are inorganic (at 4:00). Or am I wrong?
some are organic
Rohan Tuli Co-factors can be either inorganic (e.g. metal ions) or organic (e.g. flavin and heme).
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Great!
I may be wrong, but I thought that coenzymes are one of two classes of cofactors. That is to say, coenzymes are in fact cofactors, that are not ions (like Mg) but rather prosthetic groups or cosubstrates.
SLPSRocks 2 not 3 co factors and you are right
This video was so simple before I saw this comment section.
How can we unsee something?
Thanks sir
Thank you so much. It was an amazing video on the topic ..
Thankyou
Perfect.
prosthetic group is always organic in nature
Not necessarily. Prosthetic group could also be a metal ion which is an integrated part of the enzyme; a) hold the enzyme together (to maintain its catalytically active conformation); b), 1. Bind to the enzyme (usually at its active site), and hold the enzyme together; 2. and participates in the catalysis. In both cases (a & b) metal ion is a catalytically essential factor of the enzyme. Enzyme cannot perform without it.
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ThanxXx : ]
Wow
Good, but your voice is so soothing it makes me want to sleep....ZzzzzzZZZzzZ
Yeah, he needs to lay off the soy...
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Hhahahahaha
💙
All the B vitamins and only the B vitamins are coenzymes. Other vitamins are cofactors. Vitamin C is a cofactor, not a coenzyme.
Coenzymes are characterized as labile. For example, HCN is highly labile lending it's proton or hydrogen ion easily. It actually deserves the status as a B vitamin. Papain, the enzyme of papaya carica is activated by HCN.
This is highly neglected in disease research..
Great!