Nicotine therapeutics: therapeutic aspects of nicotine stimulation for brain disorders

แชร์
ฝัง
  • เผยแพร่เมื่อ 11 ก.ย. 2024

ความคิดเห็น • 99

  • @davidkellymitchell4747
    @davidkellymitchell4747 18 วันที่ผ่านมา +4

    I've used tobacco everyday since I was 15. I'm now 70 and smoking the very finest premium cigars. I'm always dealing with low blood pressure but that's mainly because I only eat once a day. You have to eat to maintain blood pressure. Added nitrates is what skyrockets BP which is the opposite of what we are told. The food industry would go out of business with no nitrates. Nitrates break down into chemicals called nitrosamines. These nitrosamines can increase your risk of cancer. Everyone that I knew that quit tobacco something went terribly wrong with their health and some didn't make it. I think in many cases nicotine acts like chemotherapy which is a poison as well. Cancer can't live in all that poison. However, lungs full of smoke is a death wish. I always dipped snuff, chewing tobacco, and smoked cigars and pipes. Never inhaled. Never been a cigarette user.

  • @randyjohnson5426
    @randyjohnson5426 4 หลายเดือนก่อน +12

    I have never smoked but after hearing Tucker Carlson talk about the positives of nicotine i started chewing nicotine gum.

  • @robertferraro236
    @robertferraro236 3 ปีที่แล้ว +51

    I'm a 45 year smoker and also recently discovered nicotine pouches. I use the strongest 8 mg type and I use at least 10 per day plus still smoke so I am taking in around 100 mg per day. The truth is that I have never felt better in my entire life than I do now. I feel a general sense of wellbeing 24/7. The additional nicotine from the pouches have a much more significant effect than smoking alone. I have never felt like I do now just based upon smoking alone. As for the blood pressure - went to the Dr for regular checkup the other day. My blood pressure was just 112/76. He was very impressed and had never heard of these pouches before. Unfortunately because of smoking getting a bad rap, the general public is completely mislead about the benefits of nicotine. It is a poison in most people's minds. There had to be a good reason why Native Americans used it and now I know why. It is one of those gifts from nature in the plants around us.

    • @RaqibZaman
      @RaqibZaman 2 ปีที่แล้ว +3

      I would suggest getting of the ciggs, and going fully on the pouches? You can find stronger ones online if you need that... have you found coffee to help with replacing some of the cigg use?

    • @richardrussell4065
      @richardrussell4065 2 ปีที่แล้ว +2

      Another thing is nicotine makes your body break down caffeine faster.

    • @RaqibZaman
      @RaqibZaman 2 ปีที่แล้ว

      @@richardrussell4065 The study I know of mentioned that for smokers, I don't know if that's true for nicotine alone.

    • @richardrussell4065
      @richardrussell4065 2 ปีที่แล้ว

      @@RaqibZaman oh I see. Still interesting nonetheless

    • @saintessa
      @saintessa 2 ปีที่แล้ว

      Pouches or patches? The transdermal ones where you put on your skin? I've got 21 mg ones that you can wear 24/7 and I've adhd so I'm gonna try see if it helps. I don't smoke quite as much ad the dosage

  • @tictactoedias1908
    @tictactoedias1908 2 ปีที่แล้ว +26

    And now apparently it’s can prevent covid 19 , true story. Studies In France 🇫🇷 I guess I’ll keep puffing away 👍

    • @Unodostres1944
      @Unodostres1944 11 หลายเดือนก่อน +1

      Da truth! 👌🏼

    • @lovellesmith2088
      @lovellesmith2088 11 หลายเดือนก่อน +6

      I have "long Haul" Covid. I have been sick for 3 years. My first piece of gum 2 mg (which is nothing) and I started dreaming again, Im up doing things.. my life is returning.

    • @travv88
      @travv88 5 หลายเดือนก่อน

      You can ingest nicotine through non-smoking methods. Smoke is bad. Look into gum or pouch.

    • @sallydroz1413
      @sallydroz1413 3 หลายเดือนก่อน

      The nicotine won't hurt u but the additional 400+ chemicals they put in cig. will kill u.

  • @living4adrenaline
    @living4adrenaline ปีที่แล้ว +14

    People sadly don't want to hear it because they asssociate nicotine with smoking. There are other methods of delivery...

    • @icy3004
      @icy3004 4 หลายเดือนก่อน +1

      Dr. Ardis is doing great work on this!

  • @JohnRBIV
    @JohnRBIV 11 หลายเดือนก่อน +12

    The blood pressure thing is interesting, I can attest to it anecdotally. I’m athletic and train in jiu jitsu and kickboxing often, my blood pressure is at times 130/70, which isn’t so bad, but when I use nicotine I’ve seen it go as low as 119/58! Maybe that’s just a stress relief aspect of it. I’m interested in seeing more data about that.

    • @carlandrews5810
      @carlandrews5810 2 หลายเดือนก่อน

      Neither of those blood pressures is bad. 120/70 is about perfect

  • @Peter-dw5xq
    @Peter-dw5xq 3 ปีที่แล้ว +22

    Absolutely fascinating. I chew 24 nicotine gums a day! Have done for over ten years. That's 168 gums per week. 720 per month. 8,760 annually. I am aproaching 120,000 consumed in total. I use it as a stimulate like coffee and as an appetite suppressant. It helps me cope with mild depression. My main concern is it will accelerate atherosclerosis...

    • @RaqibZaman
      @RaqibZaman 2 ปีที่แล้ว +5

      Coffee is probably healthier in the long run because one of its metabolites is a vasodilator.

    • @amifunnymynameisbob
      @amifunnymynameisbob 2 ปีที่แล้ว +8

      @@RaqibZaman I have adhd and use both, life quality has been much better for me since I've started having a cup of coffee in the morning + two 4mg nicotine lozenges daily

    • @RaqibZaman
      @RaqibZaman 2 ปีที่แล้ว +2

      @@amifunnymynameisbob Haha, I also go hard on the nicotine lozenges, and try to make sure to only use them while studying. It's much more effective than coffee for my ADD symptoms, and I agree that coffee pairs well with nicotine. Just trying to moderate my use, which is a little hard. The vasoconstriction it causes isn't healthy though.

    • @coryphillips1783
      @coryphillips1783 2 ปีที่แล้ว

      go on a plant based diet and don't worry about it. Check this out
      th-cam.com/video/lSwL73evUdA/w-d-xo.html

    • @richardrussell4065
      @richardrussell4065 2 ปีที่แล้ว +4

      A bit of exercise and sauna will help that risk

  • @jamesharding1488
    @jamesharding1488 7 วันที่ผ่านมา +1

    Based on what I've read, one concern I have is that nicotine breaks down collagen -- even if taken by way of patches or gum. Or does it? I wish I knew for certain, because I like nicotine, but I really care about skin health and elasticity.

  • @babycakesweetiepie77
    @babycakesweetiepie77 ปีที่แล้ว +10

    I stopped smoking and became so depressed like never before . I wonder if i started again it would save my life ?

    • @chatwithagunowner8645
      @chatwithagunowner8645 ปีที่แล้ว

      Try vaping. It's WAY safer than inhaling carcinogenic smoke. I wish you the best!

    • @lovetodocoolstuff9309
      @lovetodocoolstuff9309 ปีที่แล้ว +4

      Have you considered using a patch, gum, or nicotine pouches? Then you would get the benefits of the nicotine without the drawbacks of smoking.
      I’m so sorry that you’re depressed. Counseling can help a lot. I love BetterHelp, it’s so easy to talk to my therapist regularly…
      Well, sending love from Alaska ❤

    • @babycakesweetiepie77
      @babycakesweetiepie77 ปีที่แล้ว +1

      @@lovetodocoolstuff9309 thanks i will give it a try

    • @Morrie-queens
      @Morrie-queens ปีที่แล้ว +1

      Buy an inhalator,just nicotine and menthol,no other nasty additives.

    • @rajinevin7273
      @rajinevin7273 หลายเดือนก่อน +3

      They are not talking about smoking! Tobacco in typical mainstream cigarettes are TOXIC! They add all kinds of chemicals to them - including addictive chemicals. He is talking about PURE NICOTINE - which is NOT toxic. Completely different! Better watch the video again and do some more research.

  • @babycakesweetiepie77
    @babycakesweetiepie77 ปีที่แล้ว +5

    Man i miss smoking ,everything in my life went down hill when o stopped

    • @MMABeijing
      @MMABeijing 10 หลายเดือนก่อน +1

      Interesting,. It s been 6 months since ur last comment, how do u feel?

    • @carlandrews5810
      @carlandrews5810 2 หลายเดือนก่อน

      ​@@MMABeijingthey died

  • @saintessa
    @saintessa 2 ปีที่แล้ว +5

    Was seriously just wondering this. How nicotine patches could effect adhd being a stimulant

    • @phero9
      @phero9 ปีที่แล้ว +5

      In my experience nicotine patches can be extremely helpful as a stimulant medication at ADHD. It can give you a clear mind, it helps you focus amazingly, and treats the depression and anxiety that comes with ADHD. So it’s a real miracle treatment in my opinion. You just have to find your dose, because if the dose is too low, it won’t work, and if it’s too high, it won’t work either. So you must take your time and find the best dose for you, which can be differ individually in my opinion.

    • @JohnRBIV
      @JohnRBIV 11 หลายเดือนก่อน +1

      I have a positive personal anecdote on that. I’ve struggled with ADHD and anxiety my whole life, and even dropped out of school despite testing highly. I’m an author and artist, but I’ve had severe trouble focusing and getting work done.
      But when I smoke or chew the gum when working? Man, it really helps. I’ve tested it many times over.

    • @Lisa-ep5bw
      @Lisa-ep5bw 6 หลายเดือนก่อน

      Would you mind telling me what patch amount you started with? I have never smoked but have been thinking about trying this for adhd@@phero9

  • @smorgan125
    @smorgan125 ปีที่แล้ว +2

    Nicotine seems to raise my heart rate and make me dehydrated. Seems to be the only downside I can think of

  • @Tech_Duster
    @Tech_Duster 2 ปีที่แล้ว +16

    Why don’t you start putting nicotine pouches on Alzheimer’s patients.

    • @matthewarnspiger632
      @matthewarnspiger632 2 ปีที่แล้ว

      This guy's organization actually does that, and it has good results. th-cam.com/video/xQuD91pJLpc/w-d-xo.html

    • @AOTS123
      @AOTS123 2 ปีที่แล้ว +2

      Probably the negative connotation with the word itself. Flexibility, people. Drugs aren’t “good” and “bad”. They are compounds.

    • @rgw5991
      @rgw5991 ปีที่แล้ว +13

      The government isnt here to saves lives, just make money.

    • @rgw5991
      @rgw5991 ปีที่แล้ว +8

      Thats why any cheap/simple/free solutions they won't give you.

    • @JohnRBIV
      @JohnRBIV 11 หลายเดือนก่อน +2

      They actually are in some cases, and it seems from early trials to help.

  • @vickielemonis9528
    @vickielemonis9528 7 หลายเดือนก่อน +1

    Does anyone know if there is a detox die off from nicotine use - especially for new to nicotine users? Any information would be greatly appreciated. Thank you

  • @HappyLife-wv5ms
    @HappyLife-wv5ms 18 วันที่ผ่านมา

    Is there a follow up video on this research?

  • @Morrie-queens
    @Morrie-queens ปีที่แล้ว +5

    It also stimulates ones bowels (Dump) a few puffs on my inhalator really gets the juices flowing. 👍🏻

    • @MADSCIENTISTGONESANE6166
      @MADSCIENTISTGONESANE6166 15 วันที่ผ่านมา

      That's one of the main reasons I enjoy and consume nicotine. It helps loosen and allow for a good bowel movement. It might not always happen right away yet it helps ease the digestive system therefore when you do go, it's much easier.

  • @lumberpilot
    @lumberpilot 2 ปีที่แล้ว +6

    I would like to offer myself as a test subject for a scientific study as I am the only person I know who cannot effectively start a smoking habit even though I have the ability to fully enjoy and appreciate a good, fresh cigarette rolled with quality organic tobacco. They claim nicotine is one of the most highly addictive substances know to man and yet it hold no sway over me.

    • @marcosburgos8415
      @marcosburgos8415 ปีที่แล้ว +8

      It's not the nicotine itself that becomes so highly addictive but it's the chemical cocktail big tobacco companies use in them.

    • @user-bb3th2pl4s
      @user-bb3th2pl4s ปีที่แล้ว +2

      That’s really interesting! I would like to see people explore some of the anomalies brain chemistry. I found my mood underwent positive change with small doses of nicotine - whereas with antidepressants I just felt completely numb

    • @wutangclaney
      @wutangclaney 8 หลายเดือนก่อน

      Same boat.

    • @rajinevin7273
      @rajinevin7273 หลายเดือนก่อน +1

      It is NOT the cigarettes they are talking about. The "addiction" comes from the CHEMICALS that they put in MOST mainstream cigarettes - not in the kind you say you smoked - which is why you easily gave them out without feeling addicted. Nicotine on it's own is NOT addictive! But it is important to purchase clean, pure form of nicotine if you purchase the patches.

    • @bryang949
      @bryang949 หลายเดือนก่อน +1

      I have actually read that nicotine itself is NOT addictive at all and that when the heads of the tobacco giants declared in 1994 under oath to the US Congress that it was not addictive they were in fact telling the truth!!! However, the addiction was created by other elements of the products they were making to create the addiction. The truth of the matter is that there are many health benefits of nicotine that "the system" does not want you to know about and hence its demonization

  • @benpracht2655
    @benpracht2655 ปีที่แล้ว +1

    How does nicotene compare to coffee or other stimulants?

  • @jeanninecathcart627
    @jeanninecathcart627 2 ปีที่แล้ว +7

    Is it true that nicotine helps Chrone's disease?

    • @idaUnchained
      @idaUnchained 2 ปีที่แล้ว +2

      I’d love to know the answer to this, too.

    • @damiandamiano3651
      @damiandamiano3651 2 ปีที่แล้ว +3

      yup i am crohns and it did helped me

    • @jerrybarno7757
      @jerrybarno7757 ปีที่แล้ว

      I have Ulcerative Colitis I know it helps for that but ive heard and read that it makes Chrones worse. Reddit is packed with those answers

    • @Morrie-queens
      @Morrie-queens ปีที่แล้ว +1

      I also have IBD.High dose vitamin D3 helps along with vitamin K2. It has powerful anti inflammatory properties. You have to take 20+ thousand IU's daily. I started off with 50.000iu along with 300iu K2 daily for 2 weeks then cut down to 30.000 for 200iu K2 for another 2 weeks then went down to 20.000iu D3 200iu K2 Daily as a maintenance dose. Never felt better! A good Bcomplex is good along with extra benfotiamine B1 start low with the Benfotiamine,they come in 150mg capsules usually,take half a capsule daily for a week or 2 then increase to a full capsule,then repeat untill you've found the dose that helps you,you can eventually take up to 600mg daily.

    • @CIRSlab
      @CIRSlab ปีที่แล้ว +1

      It may help! One way in which it might is by stimulating a peptide hormone called Melanocyte Stimulating Hormone (MSH), which is produced in the pituitary/hypothalamic regions. MSH has a large number of regulating functions in the body, and one of them is gut permeability (a deficiency in MSH results in leaky gut, which results in dysbiosis, IBS, and so on). There are studies showing a strong relation between MSH and IBD. It turns out that nicotine is a potent stimulant of MSH in the brain, so I wouldn't be surprised if it's beneficial in patients with an abnormal digestive problems, particularly when the underlying cause is a deficiency in MSH. We've been able to test this hypothesis in a patient population with something called Chronic Inflammatory Response Syndrome (CIRS).

  • @damiandamiano3651
    @damiandamiano3651 2 ปีที่แล้ว +3

    thank you to give me 1000 reasons to continue smoking

    • @eshwkar7868
      @eshwkar7868 ปีที่แล้ว +1

      🤣

    • @oscar6832
      @oscar6832 7 หลายเดือนก่อน

      I'm so happy to have quit smoking.
      Good luck to all who wants to quit. 😊👍

    • @kea484
      @kea484 5 วันที่ผ่านมา

      Really, you're going to continue smoking?! Smoking is life threatening, nicotine is not. Why do it?

    • @damiandamiano3651
      @damiandamiano3651 5 วันที่ผ่านมา

      @@kea484 easy way to inject nicotine into system, small dose per day, wont harm me less than fast food

  • @tylermears2671
    @tylermears2671 ปีที่แล้ว +3

    What about the affect nicotine has on blood glucose levels? I’m concerned that using lozenges will cause my blood sugar to spike, and continuous use will increase my risk of type 2 diabetes.

    • @sigikah3916
      @sigikah3916 ปีที่แล้ว +6

      Actually it is said to increase insulin sensitivity. So it should be beneficial for blood sugar levels.

    • @MRT-co1sd
      @MRT-co1sd ปีที่แล้ว

      @@sigikah3916That’s what I heard too, better insulin activity, better I.e. lower blood sugar level.

  • @saintessa
    @saintessa 2 ปีที่แล้ว +2

    Are nicotine pouches the same as patches? (where it's absorbed through one's skin/transdermal)

    • @erinmariebaker712
      @erinmariebaker712 ปีที่แล้ว +3

      Patches are used on the skin & the pouches are used in the mouth.

    • @saintessa
      @saintessa ปีที่แล้ว +1

      @@erinmariebaker712 I had just never heard of the pouches before

    • @smorgan125
      @smorgan125 ปีที่แล้ว

      Patches don’t work very well IME

    • @swyllie30
      @swyllie30 ปีที่แล้ว

      @@smorgan125 put them in your mouth for 5 mins. It’ll work lol.

    • @rajinevin7273
      @rajinevin7273 หลายเดือนก่อน

      They are not saying pouches - they re saying patches.