PCR - Polymerase Chain Reaction (IQOG-CSIC)

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  • เผยแพร่เมื่อ 27 ธ.ค. 2024

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  • @tomtran5643
    @tomtran5643 8 ปีที่แล้ว +2333

    Learning about DNA has never been more epic.

    • @johnhogan8327
      @johnhogan8327 6 ปีที่แล้ว +15

      Now this.... This is EPIC

    • @slimetime4668
      @slimetime4668 6 ปีที่แล้ว +5

      More like annoying

    • @HiddenTalent_07
      @HiddenTalent_07 6 ปีที่แล้ว +1

      was just about to say that, and then I saw your comment.

    • @lucas3527
      @lucas3527 6 ปีที่แล้ว +1

      lol

    • @ecruz9752
      @ecruz9752 5 ปีที่แล้ว +1

      totally true !

  • @slabon6091
    @slabon6091 3 ปีที่แล้ว +911

    the music makes me feel like if i dont learn this the world is gonna end or something

    • @jirenthegray11
      @jirenthegray11 ปีที่แล้ว +17

      might appear a Monolith

    • @binitachakraborty9200
      @binitachakraborty9200 ปีที่แล้ว +5

      🤣🤣🤣

    • @yneshAshanti
      @yneshAshanti ปีที่แล้ว +14

      @@jirenthegray11I just wanted you to know at least 1 person understood this

    • @protagonist-unknown
      @protagonist-unknown ปีที่แล้ว +7

      Yea exactly it sounds like a Disney movie is going to start 😂

    • @Janayoonie98
      @Janayoonie98 ปีที่แล้ว +4

      Same 😭😭

  • @aldurocher
    @aldurocher 8 ปีที่แล้ว +539

    This is the kind of PCR explanation I've been searching for my whole life. Thanks so much.

    • @PianoGesang
      @PianoGesang 4 ปีที่แล้ว

      Yes, but what is done with the end result in the test tube?

    • @aldurocher
      @aldurocher 4 ปีที่แล้ว

      ​@@PianoGesang you can perform gel electrophoresis on it to visualize the results

    • @PianoGesang
      @PianoGesang 4 ปีที่แล้ว

      @@aldurocher Is that done by laser? I can look it up myself, thanks for the buzzword.

    • @Sameer_Malik12_u1c
      @Sameer_Malik12_u1c 3 หลายเดือนก่อน

      @@PianoGesang by using uv

  • @itszefflah5350
    @itszefflah5350 3 ปีที่แล้ว +80

    One hour lecture= Not understand about pcr
    3 minutes video with no voices= Understand everything about pcr

  • @Stepperfoot
    @Stepperfoot 8 ปีที่แล้ว +1494

    That was so dramatic lol

  • @Michaelbsav707
    @Michaelbsav707 4 ปีที่แล้ว +31

    I can never forget this solely due to the magnificent grammy-level soundtrack

  • @Vinmob01
    @Vinmob01 10 ปีที่แล้ว +116

    Love the eyes on the polymerase molecules - mischievous and full of intent!

  • @lazizasamov440
    @lazizasamov440 9 หลายเดือนก่อน +38

    That’s the most dramatic PCR ever

  • @seppukuchuan5608
    @seppukuchuan5608 9 ปีที่แล้ว +221

    Hands down the most dopest video I've viewed as far as learning more about the PCR specifically the taq polymerase :D Really helped. Thanks!!!

  • @khalfisalima2400
    @khalfisalima2400 2 หลายเดือนก่อน +16

    The music makes me feel how mind-blowing is this technique

  • @rajifusama
    @rajifusama 9 ปีที่แล้ว +570

    intro music too majestic i kenot

    • @OrnateOwl
      @OrnateOwl 8 ปีที่แล้ว +2

      +rajifusama Pls, spoodermen!

    • @saurabhtripathi9590
      @saurabhtripathi9590 6 ปีที่แล้ว

      that music was from movie 2001 a space odesye

  • @tednosaur6257
    @tednosaur6257 ปีที่แล้ว +23

    Ah yes, intense war movie music to go with some intense hard working DNA polymerases

  • @Mirrori
    @Mirrori 4 ปีที่แล้ว +15

    Our teacher always showed this video at lab tech school when we talked about PCR. But she never keeped musics on.
    Now i probably understand why.
    But yeah i understand why did she show this because this is very helpful.
    And i never got my own PCR test to work correctly in school.
    Good memories.

  • @mohangurunathan8634
    @mohangurunathan8634 3 ปีที่แล้ว +6

    This is one of the only videos which clearly explains the variable length DNA fragments that occur. Thank you so much.

  • @Chanelifiable
    @Chanelifiable 8 ปีที่แล้ว +143

    The drama. I started cracking up when the music kicked in.

    • @yeglabrat
      @yeglabrat 6 ปีที่แล้ว +1

      I sang along at the beginning to Zarathustra, and cracked up at the part where it reaches PEAK EPICNESS. I'll be sending this to my instructor friends for their students.

  • @carolvitellas8497
    @carolvitellas8497 4 ปีที่แล้ว +3

    I watched this video back in 2017 while studying for my MCAT and I ALWAYS remembered it. Now I am back for some nostalgic review, 3 years later, as a second year medical student studying for STEP 1. Still as amazing as I remembered.

  • @alexandriaalles7649
    @alexandriaalles7649 2 ปีที่แล้ว +9

    The music with the animations cracked me up!! Thanks for making! Very helpful!

  • @RinkuSingh-ed3wi
    @RinkuSingh-ed3wi ปีที่แล้ว +12

    This is why animation is best way to explain things especially in biology
    Thanks a lot ❤❤❤

  • @SynnoveJamila
    @SynnoveJamila 3 ปีที่แล้ว +18

    The music is epic. I'm studying for my exam, and I'm feeling as dramatic as this video right now.

  • @SozEmad
    @SozEmad 7 หลายเดือนก่อน +29

    the music background was so dramatic and it got happy ending 😂

  • @user-jl3lp3kc3z
    @user-jl3lp3kc3z 4 ปีที่แล้ว +11

    this is the most epic pcr video ever made

  • @justpennie5068
    @justpennie5068 ปีที่แล้ว +5

    this is amazing and pretty informative even without narration. I lowkey felt like i was watching a movie with all the dramatic and suspenseful music which added so much and kept me interested in the video. swell job!

  • @victoriavirador2699
    @victoriavirador2699 3 ปีที่แล้ว +3

    Después de presentar la PCR más de 10 veces durante la pandemia, me he encontrado este video. Lástima no haberlo encontrado antes, ¡genial!. Muchas gracias gentes del CSIC, que os vaya bien en vuestras carreras científicas.

  • @anjalikumarikashyap9141
    @anjalikumarikashyap9141 4 ปีที่แล้ว +68

    The background music scared the shit out of me at the beginning though

  • @granthuttar5755
    @granthuttar5755 8 ปีที่แล้ว +48

    Very easy to follow illustration of the PCR process. Educational and not overly complicated so many can learn from it.

  • @bangtanseva2604
    @bangtanseva2604 3 ปีที่แล้ว +12

    This is so helpful u guys cannot imagine . It's been 7 years since u posted this . Its the pandemic and students are learning from youtube . Pcr is so important. Students type in the search bar and this video comes. What a save .... I would like to thank the team .

  • @Julia-ri8cu
    @Julia-ri8cu 3 ปีที่แล้ว +9

    This music and croissant-like polymerase made me smile before my exam, thanks! I love it

    • @0n1k6
      @0n1k6 3 ปีที่แล้ว

      Makes me hungry

  • @BrigitteLP
    @BrigitteLP 4 ปีที่แล้ว +2

    Llevo 10 años trabajando como bióloga molecular y esto es de lo mejor que he vsto. Epiquísimo ¡Gracias!

  • @linafessi67
    @linafessi67 3 ปีที่แล้ว +4

    I'm a french biology student and this is an amazing video. Every student should watch it

  • @jahnavee_palsodkar
    @jahnavee_palsodkar 5 ปีที่แล้ว +2

    This is just THE BEST video about PCR I've ever watched! The animations make it really easy and fun to understand it. Awesome job guys!

  • @stamonicaswayzel7963
    @stamonicaswayzel7963 3 ปีที่แล้ว +6

    they made me understand this topic without actually saying a word. thankyou!

  • @samrobbins4520
    @samrobbins4520 2 ปีที่แล้ว +5

    I don't understand the need for this music, but good on you folks for trying to provide educational materials.

  • @wealllive2
    @wealllive2 9 ปีที่แล้ว +242

    That musics though....

    • @2201km
      @2201km 9 ปีที่แล้ว +6

      +Ang Li epic music.

    • @amarug
      @amarug 7 ปีที่แล้ว +3

      yes, 3:55 min of chronic ambivalence between "oh thanks for the useful info" and "wtf did you smoke while adding the music".

  • @Hydro.Gaming
    @Hydro.Gaming 3 ปีที่แล้ว +22

    Damn I remember seeing this video in school, now came through this as a med student. Time flies!

    • @kamalreza.m4805
      @kamalreza.m4805 3 ปีที่แล้ว +1

      Goodluck bro

    • @elpidakeremidou3702
      @elpidakeremidou3702 3 ปีที่แล้ว

      true dat..

    • @Anupamchess
      @Anupamchess 8 หลายเดือนก่อน

      Bruh bro is going to become a doctor while having 26k subscribers on his Gaming channel...💀
      Mad respect bro

    • @Hydro.Gaming
      @Hydro.Gaming 8 หลายเดือนก่อน

      @@Anupamchess thx lol

  • @saibaba1106
    @saibaba1106 10 ปีที่แล้ว +24

    It was seriously amazing....now I can easily understand and write my exam well!

  • @TemeraireBjartskula
    @TemeraireBjartskula 6 ปีที่แล้ว +2

    This is simply incredible! Definitely one of the best (study) videos in existence... the animations make sense and the music totally finishes it

  • @waffles764
    @waffles764 ปีที่แล้ว +5

    Ugh I’ve been stressing on what exactly is happening during a pcr. This helped so much thank you

  • @maxsteinberg7350
    @maxsteinberg7350 8 หลายเดือนก่อน +16

    this video >>>> the ~50 slides my prof gave us for pcr

  • @hikingnorth9043
    @hikingnorth9043 4 ปีที่แล้ว +7

    BRUUH the music, I can't.
    You could make an epic trilogy with this soundtrack

  • @andreainzaghi7373
    @andreainzaghi7373 4 ปีที่แล้ว +3

    the best short video I have seen. Even if it is short, it is very explicative. Number one!!

  • @rulamudhafar7930
    @rulamudhafar7930 5 ปีที่แล้ว +3

    How simple and smart this explanation is !!
    How great your efforts are. Thanks ,many thanks !!

  • @Sameer_Malik12_u1c
    @Sameer_Malik12_u1c 4 หลายเดือนก่อน +6

    10 years of making this video.. Still how amazing 😮😮

  • @KristysEdits
    @KristysEdits 4 ปีที่แล้ว +25

    Best explanation ever

  • @DeceptaconAgain
    @DeceptaconAgain 3 ปีที่แล้ว +10

    I liked the epic music, it actually made me more engaged.

  • @CarterColeisInfamous
    @CarterColeisInfamous 10 ปีที่แล้ว +20

    i love how epic it this is... really helps you feel the power and gravity of the reaction

  • @kayo6689
    @kayo6689 ปีที่แล้ว +4

    This makes the # of PCR copies so clear... no one told me that sometimes variable-length target sequence DNA is counted as a copy of the target sequence too!

  • @studybiotic
    @studybiotic 2 ปีที่แล้ว +23

    well done and thx for this dramatic music

  • @jessicakwiecinski
    @jessicakwiecinski 5 ปีที่แล้ว

    Why did I almost cry. Never been more impressed by a lesson on PCR

  • @weizhang6938
    @weizhang6938 ปีที่แล้ว +3

    one of the best demonstrations I have ever seen on this subject!

  • @DarthGangsta
    @DarthGangsta 4 ปีที่แล้ว +1

    My bio professor told me in a hw assignment to find a video explaining PCR and post a link in my response. I've found the ideal video.

  • @ValentinaHGomes
    @ValentinaHGomes ปีที่แล้ว +5

    thank you so much!! the animation really helps to understand the whole process!! big thanks from brasil!

  • @malinideori4966
    @malinideori4966 3 ปีที่แล้ว +2

    I have studied pcr from multiple books but today after watching your videos I learnt about pcr to the core..now I have no doubts.. n thank you so much for putting this up😃😃😃😃

  • @charanSparsh7
    @charanSparsh7 ปีที่แล้ว +8

    You don't know, How much you have helped Indian pre medical exam aspirants 😂

  • @Linkmon99
    @Linkmon99 4 ปีที่แล้ว +47

    THX I PASS BIO NOW

  • @sciencesynergy-g4h
    @sciencesynergy-g4h ปีที่แล้ว +6

    I even clapped for you🤗🤗...you made I felt the animation...whoever is behind this video should keep it up

  • @Yousefmmohammed
    @Yousefmmohammed 4 ปีที่แล้ว +3

    Honestly that cool video is a real representation of what the word 'creativity ' really means .

  • @proximacentauri2684
    @proximacentauri2684 5 ปีที่แล้ว +23

    It's 6:43 in the morning. I spilled my coffee like something out of a sitcom lol the music scared the shit out of me. good video though

  • @Bookworm23184
    @Bookworm23184 ปีที่แล้ว +6

    This is the most useful video i've ever watched

  • @isadorah4969
    @isadorah4969 8 หลายเดือนก่อน +13

    Why is this video keeping my serotonin high af

    • @bxbybxnny5640
      @bxbybxnny5640 5 หลายเดือนก่อน

      the bgm is sexy

  • @elisenitouche2371
    @elisenitouche2371 11 หลายเดือนก่อน +16

    D-polymerase looks like it's judging me. I love it.

    • @ReemShamil
      @ReemShamil 10 หลายเดือนก่อน

      ikr

  • @mridulverma2516
    @mridulverma2516 2 ปีที่แล้ว +21

    The music is just......Like Something Akashvaani is goin to happen...👌😂😂

  • @sivasankarisiva2919
    @sivasankarisiva2919 3 ปีที่แล้ว +4

    Super animated explanation. A voice without speech

  • @nihatola7929
    @nihatola7929 4 หลายเดือนก่อน +6

    2024 and this is still better than all the other videos

  • @tracy4259
    @tracy4259 2 ปีที่แล้ว +7

    Simple, clear, thorough. Thank you.

  • @shazleenatasha
    @shazleenatasha 4 ปีที่แล้ว +10

    the background music is so epic until it leaves marks(memories) in my brain. thanks!!!

  • @caro_alexandra
    @caro_alexandra 3 ปีที่แล้ว +4

    Cortito y al punto, excelente video!!
    Se entendió todo perfectamente, muchas gracias!

  • @meow5692
    @meow5692 2 ปีที่แล้ว +5

    Back ground music almost got me heart attack but yup animation was just amazing , thank you everyone who were involved .

  • @danielg1680
    @danielg1680 4 ปีที่แล้ว +4

    I'm crying 😢 because this video really helped me a lot....
    Thanks

  • @sujathaprabhakar769
    @sujathaprabhakar769 6 ปีที่แล้ว +4

    Best video about PCR. Thanks and big salute to the entire team

  • @efinate002
    @efinate002 7 หลายเดือนก่อน +5

    I always come back to this video whenever i have an exam amazing video

  • @tanyajain9950
    @tanyajain9950 9 หลายเดือนก่อน +14

    Concept is clear🎉❤
    But the background music was so dramatic😊
    It seems that it's the most daunting task existing 😅😅

  • @Na-sf6ns
    @Na-sf6ns 5 ปีที่แล้ว +2

    Respect ! Why cant every video be so perfect and clear !

  • @lindamarialal
    @lindamarialal 9 ปีที่แล้ว +149

    That background music though! X'D

  • @교사마재열
    @교사마재열 3 ปีที่แล้ว +5

    The animation is great. I'm a Korean school teacher, so you can use this video as a background for education.

  • @wajihazahoor2530
    @wajihazahoor2530 2 ปีที่แล้ว +4

    The best video I've seen and the explanation through pictorial representation is so good

  • @nihaljagtap4873
    @nihaljagtap4873 3 ปีที่แล้ว +10

    It's really helpful and kinda humorous too bcoz of music👌🏻

  • @bernardohochman9100
    @bernardohochman9100 4 ปีที่แล้ว +3

    Este video es increible! Horas tratando de entender el tema, hasta ahora. GRACIAS!

  • @ihanba
    @ihanba 5 ปีที่แล้ว +1

    Why can't I like this video more than once? It's excellent!

  • @iiiiiiiii6579
    @iiiiiiiii6579 4 ปีที่แล้ว +17

    I laughed way too hard because of the music, thank you

  • @frapechinokelsey6451
    @frapechinokelsey6451 4 ปีที่แล้ว +6

    I'm in 12 standard from INDIA 🇮🇳 & I found this video which really boosted my knowledge ☺

  • @dicle743
    @dicle743 ปีที่แล้ว +5

    The best animation video on PCR

  • @carlosalmeida8435
    @carlosalmeida8435 4 ปีที่แล้ว +2

    Thank you very much for this video, finally I understand why there is much more copies of the desired DNA region than the variable lenth DNA. GOD bless you!

  • @mahmoudsweda8012
    @mahmoudsweda8012 3 ปีที่แล้ว +12

    the music makes me feels I am having a dance with the PCR😂😂😂

  • @TrustySteeringWheelTray
    @TrustySteeringWheelTray 6 ปีที่แล้ว +1

    Whoever selected the music for this video deserves an award.

  • @marianaarroyo5835
    @marianaarroyo5835 ปีที่แล้ว +6

    Great video! Absolutely loved the background music! Incredible!

  • @Ardyrobeats
    @Ardyrobeats 3 ปีที่แล้ว +1

    The dramatic sound effects is off the charts!

  • @bhavyaupadhyay794
    @bhavyaupadhyay794 11 หลายเดือนก่อน +7

    Such a intense music made me feel i can do anything after learning this

  • @user-ri8ps6cl4w
    @user-ri8ps6cl4w 3 ปีที่แล้ว +19

    great video, but the music choice is... interesting

    • @sakhti9962
      @sakhti9962 3 ปีที่แล้ว +2

      I muted it, felt it was way too distracting.

  • @nvm7430
    @nvm7430 7 หลายเดือนก่อน +6

    This really helped me! I study medicine in Belgium

    • @F.Z7OCT
      @F.Z7OCT 7 หลายเดือนก่อน +1

      Meee toooo..... Studying MED in Damascus ♥♥♥♥♥

    • @Panther-zyx
      @Panther-zyx 6 หลายเดือนก่อน

      Me tooo ! In which year are you ?

  • @_LAA406
    @_LAA406 3 ปีที่แล้ว +3

    I have never seen any video more easily understandable than this...👍

  • @maudlyn2685
    @maudlyn2685 3 ปีที่แล้ว +7

    Love it! so magical and self explanatory.

  • @quentin-v9d
    @quentin-v9d 4 ปีที่แล้ว +5

    Great video, in my head I was picturing the off target amplicons (the ones that are from original template and extend beyond the reverse primer) and I was picturing that you would get a amplicons of a variety of sizes over the thickness of a band of agarose. Which apparently is correct but is irrelevant as the target amplicons quickly dwarf the off target ones in number.

  • @planetyam6044
    @planetyam6044 5 ปีที่แล้ว +10

    in my exam : " explain about the PCR technique".
    my head: _2001 music starts playing_

  • @katherynding7905
    @katherynding7905 2 ปีที่แล้ว +4

    you saved me from tomorrow's quiz. Thank you alot

  • @omerita1000
    @omerita1000 2 ปีที่แล้ว +13

    what's with the dramatic music?!

  • @garyy.7
    @garyy.7 2 หลายเดือนก่อน +7

    This is the simplest explanation yet fun to watch. lol

  • @millssJ
    @millssJ 8 ปีที่แล้ว +27

    Fiiiiinally I understand what this is about. Thank you!

  • @adrijachakrabarti6110
    @adrijachakrabarti6110 ปีที่แล้ว +5

    The concept just got crystal clear, thanks a ton❤

  • @davidcune314
    @davidcune314 9 ปีที่แล้ว +78

    i understand PCR thank to you , ready for the semester exam o/

  • @arunakapalinee3623
    @arunakapalinee3623 2 ปีที่แล้ว +6

    This video should go for oscar award