Can someone explain the part about how far apart the genes are? I get his analogy but I don't know why that relates to genes having a higher chance to cross over the farther apart they are.
Crossing over is a mostly random process. And for crossing over to break linkage, it has to occur between two genes, so that way one of the genes stays the original, and the other get exchanged for the gene on the homologous chromosome. So now I have a chromosome that has one original gene and one from the homologue. We call the a recombinant chromosome now. If crossing over occurs before or after both genes, while part of the chromosome is swapped, the two genes still remain together, so linkage remains. Because this is a generally random process, you are more likely to cross over in between the two genes if they are farther apart because there are simply more places on the chromosome crossing over could happen that ARE between the two genes. If they are close together the "in between" becomes a smaller target and therefore less likely to happen by a generally random process. If you think of breaking linkage as hitting a target, and the target is the area between the 2 genes on the chromosome then, genes that are close together are simply a smaller target by definition. That makes the target harder to hit. Hitting the target causes linkage to break, so they would be expected to break linkage more rarely than a larger target (genes far apart). Hope that helped.
Haha. I love your dry humor! Makes it a lot more enjoyable.
bit rude.
A A it’s not an insult...
I love ur analogies
0:54 "Chapter fift-GENE."
very helpful thanks
Thank u!! This makes everything easier. ☺
Can someone explain the part about how far apart the genes are? I get his analogy but I don't know why that relates to genes having a higher chance to cross over the farther apart they are.
Crossing over is a mostly random process. And for crossing over to break linkage, it has to occur between two genes, so that way one of the genes stays the original, and the other get exchanged for the gene on the homologous chromosome. So now I have a chromosome that has one original gene and one from the homologue. We call the a recombinant chromosome now.
If crossing over occurs before or after both genes, while part of the chromosome is swapped, the two genes still remain together, so linkage remains.
Because this is a generally random process, you are more likely to cross over in between the two genes if they are farther apart because there are simply more places on the chromosome crossing over could happen that ARE between the two genes. If they are close together the "in between" becomes a smaller target and therefore less likely to happen by a generally random process.
If you think of breaking linkage as hitting a target, and the target is the area between the 2 genes on the chromosome then, genes that are close together are simply a smaller target by definition. That makes the target harder to hit. Hitting the target causes linkage to break, so they would be expected to break linkage more rarely than a larger target (genes far apart).
Hope that helped.
Thanks for the explanation, I think I get it now.
Instructions unclear my friend cut my finger off 💀
Great video:)))
can you translate turkish please
Cheerst mate