For some reason, people are having a difficult time understanding why gram positive bacteria is more receptive to antibiotics than gram negative. Even though gram positive has that thick peptidoglycan layer, it lacks that outer membrane that the gram negative has. Thus, it takes a rather strong antibiotic to fully penetrate the membrane of the gram negative bacteria and to completely thwart its process.
Pretty close. You are correct that the semi-permeable nature of the outer membrane interferes with drug entry, but it is completely unrelated to the 'strength' of the drug. It has to do with the chemistry of the drug and its ability to cross the outer membrane.
gram negative pili on the outer membrane are “slimy” in nature that protect and prevent antibiotics from binding to specific antigens. Whereas gram positive’s thick cell wall is predominantly sugar and amino acids formed in a “sugar lattice” arrangement thus is easier to penetrate and break down
came here not knowing the difference between Gram positive and gram negative bacteria, and now i am leaving with knowledge of gram-positive and gram negative bacteria :) subscribed
This is a VERY basic demonstration of the differences between Gram + and Gram -. tetra-peptides are the cross links between NAG and NAM that make up the peptidoglycan cell wall, Teichoic acid are also found only in Gram + although its function is not well understood. on the other end, lipoteichoic acid, in some bacteria, is made out of 60% wax, which is able to prevent the cell from drying out (making it more difficult or water to escape). As for Gram -, lipopolysaccharide, is made out of sugar monomers covalently bound to the phospholipid bilayer whose hydrophilic head are the endotoxins she was talking about.
Hi. Very useful vid. Just cleared my head about this topic. Thanks for putting out this content which I am sure will be useful to many others. I know it was a big help for me.
Probably because the peptidoglycan layer of gram-positive bacteria is so thick that it provides extra support and structure relative to the thin layer and gram negative bacteria
Very nice quick summary! To the point. I'm trying to understand better how taking (or not taking) the Gram stain affects the resistance antibacterials, and it seems the double wall of the Gram negative may make it tougher to kill. But from the bacteria's standpoint, does the double wall create constraints, like slower absorption of gases and nutrients, or make the cell less responsive to stimuli?
Does anyone know which of the two types is most susceptible to antibodies? I thought it would be gram-positive bacteria because of the thicker peptidoglycan layer and the lack of porins...
mam plz tell me whether my defintion is correct or not. the system which consists of brain spinal cord nerves and sensory organs is called nervous system.
Because all their guts spill out!!! Seriously, when the cell wall lyses open, all of the cytoplasm inside the cell wall will spill out and the bacterial DNA will start to break down. It is a death sentence for the cell.
I think you are referring to one of the components of peptidoglycan, which contains peptide chains and sugar molecules. These form a mesh-like structure outside the plasma membrane of most bacteria cells. The peptide chains are linked to each other as well as to repeating sugar molecules. This creates a strong cell wall to protect the plasma membrane of the bacteria cell. You can find more information on wikipedia: en.wikipedia.org/wiki/Peptidoglycan
Gram + have teichoic acid to link the peptidoglycan layers (NAG and NAM) together. Gram - do not need the teichoic acid because their layer of peptidoglycan is much thinner.
Why is it not indicated which side is the INNER part of the wall and which is the OUTER part of the wall? Without that information, I find this video irritating to watch. It's something essential that is not mentioned.
It is indicated. The *outer* membrane is clearly labeled for Gram-negative cell walls. The cytoplasm (which is quite obviously *inside* the cell) is also clearly labeled for both. I also verbally refer to things as inside/outside. Your irritation seems to be rooted in your own impatience and inability to read.
am i right i dont understand. plz if it is correct then i will maintain it bec my students hv written it in their note book. basically i m chem teacher but an extra task has given to me nd i teach biology that is why i take help frm u thanks for cooperation.
I'm pretty sure your definition is fine. The nervous system consists of 'nerves'. where do we find these nerves? In the brain, spinal cord and peripheral nerves (sensory and motor nerves). Basically, the Nervous system is made up of the central nervous system (brain and spinal cord) and peripheral nervous system (consists of all other nerves that branch off the spinal cord and into our other body parts tissues)
For some reason, people are having a difficult time understanding why gram positive bacteria is more receptive to antibiotics than gram negative. Even though gram positive has that thick peptidoglycan layer, it lacks that outer membrane that the gram negative has. Thus, it takes a rather strong antibiotic to fully penetrate the membrane of the gram negative bacteria and to completely thwart its process.
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Gram negative are more resistant to antibiotics than gram negative due to pili present in gram negative bacteria
What!!!!! how can the 2 negative, 😡
Pretty close. You are correct that the semi-permeable nature of the outer membrane interferes with drug entry, but it is completely unrelated to the 'strength' of the drug. It has to do with the chemistry of the drug and its ability to cross the outer membrane.
gram negative pili on the outer membrane are “slimy” in nature that protect and prevent antibiotics from binding to specific antigens. Whereas gram positive’s thick cell wall is predominantly sugar and amino acids formed in a “sugar lattice” arrangement thus is easier to penetrate and break down
You just saved my life. Thank you for simplifying this concept! You are a great teacher!!
😊😊😊
yes really
I like you ❤️
I watched, I listened, I learned, I liked, I subscribed, I smiled
i`m studying for a test tom, it is really helpful and easier than my instructor's handouts.
Professor I am a novice biochemist. thanks for your effort. your videos are helping me to achieve the basic of microbiology.
Yes
Same!
You teach way better than my teacher! Thanks for the video
I'm happy that your videos still exist ❤ it's been 6 years
Yes, I still try to post new ones, but life is busy.
You discussed everything really well and concisely. Thank you so much for this!
i just love how you pronounced the bacteria without stress
Um yes.... I wish I could give you a big hug cause this condensed everything I need to know nicely.
@@devinbreckmann8956 I'm now a nurse and I've been practicing for a year.
That’s great! Congratulations! 🎉
Ma,am you have amazing style for explained this
Thank you
Also you bicep and triceps locking so good
came here not knowing the difference between Gram positive and gram negative bacteria,
and now i am leaving with knowledge of gram-positive and gram negative bacteria :)
subscribed
You just made this so FREAKING easy, thank you!
Simplicity at its best in Microbiology !!! Fantastic way to explain it.
Thank you so much. You made this subject 1000x more understandable.
This is a VERY basic demonstration of the differences between Gram + and Gram -. tetra-peptides are the cross links between NAG and NAM that make up the peptidoglycan cell wall, Teichoic acid are also found only in Gram + although its function is not well understood. on the other end, lipoteichoic acid, in some bacteria, is made out of 60% wax, which is able to prevent the cell from drying out (making it more difficult or water to escape). As for Gram -, lipopolysaccharide, is made out of sugar monomers covalently bound to the phospholipid bilayer whose hydrophilic head are the endotoxins she was talking about.
Great explanation of this..I didn't think it was going to be a great explanation on TH-cam..Nice work.
it was my first time watching your video. that were good a lot and understandable enough, thank you for making such good videos.
Ya bro i am indian and it is so explained i can also hold it good
Hi. Very useful vid. Just cleared my head about this topic. Thanks for putting out this content which I am sure will be useful to many others. I know it was a big help for me.
It helped me a lot, tks. The lecture is very clear, easy to understand that helps me much in study.
Thank you for a very clear and easy to follow lecture!
Excellent video, very well explained, and really simple.
Mam you are best in microbiology 🙌🙌🙌just cleared my concept ..it's fantastico
Thank you!
I'm from India ..love this mam
The best summery ever
😃
You explain it really clear! Good job! :)
If i pass my exams today it'll be because of this lecture
Why are gram negative bacteria usually much easier to disrupt by sonic oscillation than gram positive bacteria?
Probably because the peptidoglycan layer of gram-positive bacteria is so thick that it provides extra support and structure relative to the thin layer and gram negative bacteria
Awesome vid, very helpful. Thanks
Thanks juvarg99!
Biology Professor
Very nice quick summary! To the point. I'm trying to understand better how taking (or not taking) the Gram stain affects the resistance antibacterials, and it seems the double wall of the Gram negative may make it tougher to kill. But from the bacteria's standpoint, does the double wall create constraints, like slower absorption of gases and nutrients, or make the cell less responsive to stimuli?
This was so helpful! Clear and understandable.
The best lecture ❤️❤️❤️
Nice madam ,very well explaination gram + ,- bac....
This video helped me so much. Thank you for posting
Does anyone know which of the two types is most susceptible to antibodies? I thought it would be gram-positive bacteria because of the thicker peptidoglycan layer and the lack of porins...
Thank you very much for the above info.
Thank you so much for this informative video. I just started learning bio ans this video really helps alot! Thumbs up! 🖒
thanks for great explaining
awnyuse izwi ntombi..your video was very helpful. thank u
Very nice video!
mam plz tell me whether my defintion is correct or not. the system which consists of brain spinal cord nerves and sensory organs is called nervous system.
Sounds good to me.
Thank you for the help, I appreciate it
What is the difference b/w lipoteichoic and teichoic acid ? Are they same ?
Thanks man for give the knowledge bacteria
Love your video! Can you please upload more videos? It so helpful =)
Mam please a leacture on basics of immunology
Great video
Doctor, please explain the anthrax and its causes
Caused by Bacillus anthracis, a bacterium
Thank you very much it was very useful and please audiences do not use course language in your comments. thanks
thank you very much your very easy to understand and you break things down well. thanks a bunch
thanks
this is amazing, thank you
Great Video!
Why the endospore found in gram posative bacteria only????please answer me..i have exam in this question tomorrow😭😭😭
Great! so simple but very mean full and helpful.
Exellent class!
Nice video but expected how gram staining works on both ...
Check out my other video on the Gram Stain. It’s all there!
Great Job !
great video, very clear expanation
thank you very much!
Thanks🌹
Your videos help me a lot! Thank you very very much!!! God bless you :)
@@devinbreckmann8956 woah! hey there 🙂 I am now a licensed Pharmacist for more than 5 years in between 2 hospitals, Good to hear from you 🙂
Congrats! That’s great news! :)
@@BiologyProfessor thank you! More power to your channel ❤👍👍👍
aside from being intelligent, you also are beautiful! you're video is helpful since I'm preparing for the board exam in microbiology. Thank you!
The only reaon to love biology
A small quibble: it should be Vibrio cholerae (e at the end). Very nice otherwise.
omg you're so awesome! thank you for this video =)
why some bacteria are gram positive while others are gram negative?
I loved it so much.
How can I contact with u ? U r explanation is good.
Scientific names are supposed to be underlined when written.
very helpful. Thanks a lot
Gracias por el video.
Thanks you mem
Nice class miss
Thank you!
thank you for your video! :) (Btw, I think it's Vibrio cholerae)
Fantastic! Thank you!
when bacterial cell wall burst they will die why?
Because all their guts spill out!!! Seriously, when the cell wall lyses open, all of the cytoplasm inside the cell wall will spill out and the bacterial DNA will start to break down. It is a death sentence for the cell.
thanks a lot mamm!
Doing well mam
THANK YOU
thanks, i love your video
thank you 😭😭😭
Brilliant mam....
Thanks :)
Mam i am from india
Mbbs aspirant
what about peptide linkage ?
I think you are referring to one of the components of peptidoglycan, which contains peptide chains and sugar molecules. These form a mesh-like structure outside the plasma membrane of most bacteria cells. The peptide chains are linked to each other as well as to repeating sugar molecules. This creates a strong cell wall to protect the plasma membrane of the bacteria cell. You can find more information on wikipedia: en.wikipedia.org/wiki/Peptidoglycan
Gram + have teichoic acid to link the peptidoglycan layers (NAG and NAM) together. Gram - do not need the teichoic acid because their layer of peptidoglycan is much thinner.
Biology Professor thanks mam!
happy to c ur rply
btw u r fantastic
the way u teaches is just awesome!
Madam wants to contact you to discuss few question.
Great video, excellent explanation.
One think u need is a voice cancellation mic =)
This is one of the first videos I ever filmed. I have more sophisticated equipment now. :)
Uniquе Yeаst Infесtion SуstеmHow tо gеt lаsting Candidа freedоmCаndidа Curе e-boоk Rеvеееаls Аll twitter.com/ebe81ce7a4578e102/status/784262969735516160 Grаm PРositive Bаctеriа vs Grаm Nеgative Bacteriа
Why is it not indicated which side is the INNER part of the wall and which is the OUTER part of the wall? Without that information, I find this video irritating to watch. It's something essential that is not mentioned.
It is indicated. The *outer* membrane is clearly labeled for Gram-negative cell walls. The cytoplasm (which is quite obviously *inside* the cell) is also clearly labeled for both. I also verbally refer to things as inside/outside. Your irritation seems to be rooted in your own impatience and inability to read.
plz mam upload a video on protein structure plz.
You are the second person to make this request. It's on my list, but it will probably be a few weeks! Thanks for the suggestion. :)
Thanksa a lot
Thank you
You are welcome!
thank you very much ☺☺
thanks alot
AL salam Aleekum.....thank u very very much your video is great 😙😙😙😙😙😙
+nahla jowad what does salam allekum mean?
+Boom Box its mean peas up on you in arabic ....... its our greeting
nahla jowad
but that girl is not arabic
+nahla jowad Why would you say that looooooooooooooool. Bet this guy is not even muslim.
+Sdzc Sxcsdzx ok Iknow but it is our greeting and it has a beautiful meaning. ....
She sounds like "Vanelopee" from "Wreck it Ralph" !!! Isn't she??
thanks a lot ,very helpful :)))
am i right i dont understand. plz if it is correct then i will maintain it bec my students hv written it in their note book. basically i m chem teacher but an extra task has given to me nd i teach biology that is why i take help frm u thanks for cooperation.
I'm pretty sure your definition is fine. The nervous system consists of 'nerves'. where do we find these nerves? In the brain, spinal cord and peripheral nerves (sensory and motor nerves). Basically, the Nervous system is made up of the central nervous system (brain and spinal cord) and peripheral nervous system (consists of all other nerves that branch off the spinal cord and into our other body parts tissues)
thanks
Hey I liked the teacher. Though
simple to digest
Hi
Great explanations
Thanks🌹
shes very beautiful teacher!!!!!!!!!!!!!!!
of course you would look at the teacher and not the content lolz:P
Informative....