ฝัง
- เผยแพร่เมื่อ 15 ต.ค. 2024
- Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr Wise Young M.D., Ph.D., the Richard H. Shindell Chair in Neuroscience, Distinguished Professor of Cell Biology & Neuroscience and the Founding Director of the W. M. Keck Center for Collaborative Neuroscience at Rutgers University.
If you enjoy this interview please donate to ideaXme here radioideaxme.c....
Spinal Cord Injury
A spinal cord injury (SCI) is defined as any damage to the spinal cord that causes temporary or permanent changes in its function.
Depending on the location and severity of the damage, the symptoms vary, from numbness to paralysis to incontinence. Long term outcomes also vary widely, from full recovery to permanent quadriplegia or paraplegia. Complications can include muscle atrophy, pressure sores, infections, and breathing problems.
Direct medical expenses for spinal cord injuries can run into millions of dollars (not including lost wages and earning potential) and can include: spinal surgery, trauma care (use of a ventilator) rehabilitation (including physical and occupational therapy, speech therapy, and mental health counseling), long-term care, including the costs of in-home aides, medical equipment such as wheelchairs, and medication such as painkillers and antibiotics.
Dr. Wise Young
Today’s guest is going to take us further into the area of spinal cord injury as well as discussing some of the most exciting work that’s going on in the development of innovative therapeutic intervention for SCI. Today’s speaker is Dr. Wise Young, who with a Doctorate in Physiology and Biophysics from the University of Iowa, and a medical degree from Stanford University has committed himself to bringing innovative treatments to people with spinal cord injuries over the last few decades.
Speaking on how he felt compelled to work in tackling spinal cord injuries, Dr. Young expresses how “I was an intern at Bellevue Hospital when I took care of my first spinal cord injury patient. It was very emotional for me because I think one of the things that all doctors hate to feel is helpless, to feel as if there's nothing you can do.”
He continues, “this is really one of the most hopeless conditions in human history where patients are told that they will never walk again. And so, I decided to take on a subject that I think most of my colleagues believed would be a waste of time.”
Dr. Young led the team that discovered and established high-dose methylprednisolone (MP) as the first effective therapy for spinal cord injuries. This 1990 work upended concepts that spinal cord injuries were permanent, refocused research, and opened new vistas of hope.
He also developed the first standardized rat spinal cord injury model used worldwide for testing therapies, formed the first consortium funded by the National Institutes of Health (NIH) to test promising therapies, and helped establish several widely accepted clinical outcome measures in spinal cord injury research.
Speaking on the development of the Phase II trials, Dr. Wise explains how he first witnessed them take place in Kunming, China. “There was an army hospital there that really did something very unusual. They were taking patients after spinal cord injury and walking them six hours a day, six days a week for six months. It was called the six, six, six program. This caused many of the patients to recover function, I mean, as many as half of the patients recover walking.”
His work has been featured in numerous national and international news and print publications including appearing on 20/20 with Barbara Walters and Christopher Reeve, Today with Katie Couric, 48 Hours, Fox News, CNN, and USA Today. TIME Magazine named Dr. Young America’s best in spinal cord injury research.
Some of his many honors include: being the first researcher elected to the Spinal Cord Injury Hall of Fame, receiving NIH Jacob Javits Neuroscience "Cure" Award, a Trustees Award for Excellence in Research, an Asian American Achievement Award, and The Hope Award.
Here Dr. Young talks of:
About his background, how he became interested in science, physiology and medicine, and how he finds himself at the epicenter of neuroscience and trauma care. He will discuss his cell therapy approaches in SCI and his supportive interventions in SCI. He will also talk about his "morphodynamic" interventions in SCI and go into his international work in Asia and Norway.
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As a quadriplegic, it's really nice to hear everything we're not told about! Thank you to this channel and dr. Young. I'm looking forward to do a six six six!
Hi Thank you for your comments. I am so happy to hear that this interview was useful for you. We'll pass on your comments to Dr Young. If you'd like us to cover any other areas that could be useful and/or interesting for you (medical research that would affect you) - please email me andrea@ideaxme.com and we will see what we can do to track down a world leader in the field you suggest to interview. ideaXme is also an audio podcast on 10 channels - iTunes, Spotify, Stitcher, Radio Public, SoundCloud....you can read about our organisation and interviews here www.radioideaxme.com and connect with us on Twitter @ideaxm and on Instagram @ideaxme. With best wishes - keep watching and listening! Andrea Macdonald Founder ideaXme
Dr. Wise Young is an amazing man. He gets it. I met him 15 years ago and I still bet on him every day. Thank you for your relentless pursuit to eradicate paralysis.
Hi Mike, We'll pass on your comments to Dr Wise Young. Thank you for watching. You can also listen to ideaXme interviews on 10 audio platforms - including iTunes, Spotify and Google Podcasts. Our blog for the links and text supporting our interviews is here www.radioideaxme.com. Connect on Twitter @ideaxm and on Instagram. With best wishes, Andrea Macdonald founder ideaXme
If you expect to milk from the bull, you can count Dr. Wise Young. He doesn't know
real stem cell therapy indeed. He came to Taiwan and made a lot of bullshit statements.
In the end, nothing happens.
No..check out nvg 291
@@ideaXmeany updates on him trials?
As an incomplete C5/6 quadriplegic for eleven yrs, and having more than my fair share of incontinent episodes, struggles with walking, and now, for the past five years, very difficult to heal vascular stasis ulcers, on the back of my calves, from lymphedema; I can't tell you how very grateful I am to Dr Young for his research and dedication to our cause for so many years. His research is already having a far reaching positive outcome for many various disorders. It's a crying shame that the majority of umbilical stem cells are simply being discarded, when the potential to help so many is at stake. Thank you, first to Ira, for highlighting our plight here in the SCI world, and secondly, to Dr Young, for your tireless devotion. With your compassion, you've taken the patient from being treated in a barbaric manner, to that of one of exceptional hope. No amount of gratitude could ever express my own personal gratefulness. Looking forward to my time when I receive this revolutionary treatment, and with a dedicated mindset, faithfully fulfil the six-six-six program to a better life. Thank you again!!
Flyin Arris I am delighted to hear that you found the interview with Dr Wise helpful. You are brave and have clearly had a very tough time. I am very sorry. All the very best to you. Andrea, founder ideaXme. This interview is also available in audio format here www.radioideaxme.com.
This channel is amazing! Amazing people and an amazing host! I am sharing your videos in my Bioinformatics community.
Kind of sense here a future Nobel prize.
Almost 5 years on weel chair this man give me hope
Great channel! Thanks for the good work, Ira! And of course Big Thanks to Dr. Young!
Hi Julian, I am so happy to hear that you love our channel. I will pass on your comments to Ira and Dr Wise Young. You might be interested to hear that we are also on 10 audio platforms - iTunes, Spotify, Radio Public, FM Player, Stitcher and more..You can also find our blog here www.radioideaxme.com Connect with us on Twitter @ideaxm and on Instagram @ideaxme Andrea Macdonald, Founder ideaXme Move the human story forward! Please spread the word!!!
Another fantastic interview! Keep up the good work.
Thank you. So happy to hear that you like our work. I will pass on your comments to Ira our exponential health ambassador who as you know conducted this particular interview. Andrea Macdonald, Founder ideaXme
I squeezed the technique 6-6-6 and brought it to one month.
An optimized rehabilitation the SCI patients tolerate easily and often only one assistant is required.
I wrote to Wise Young about this work several years ago, but unfortunately, my letter seems to have not reached him.
Thank you for your response. We have no idea why you did not receive a response of course - maybe try again? You can also find our interviews in audio format on 10 platforms including iTunes, Google Podcasts and Stitcher, alternatively you might like to visit our blog where we also publish interviews. All the very best of luck to you. Regards, Andrea Macdonald founder, ideaXme
@@ideaXme Thank you for advice. I will write another letter to Wise Young soon.
@@WalkingRehabilitation Good luck.
Hi iosif can you give more information about how paraplegia patient can do 6-6-6 program.
@@santhoshsrinivasan8111 The 6-6-6 program means walking ability rehabilitation on the treadmill with partial body weight support for six hours a day, six days a week for six months.
It is very expensive and noneffective in case of complete para or tetraplegia by spinal cord injury. Perhaps someone will be lucky but the majority of people just lose money. It is a highly profitable business and it seems that it will stay unchangeable.
The sample of the 6-6-6 procedure seems like on this video: th-cam.com/video/gTQ5PdF_YR8/w-d-xo.html
My 45 year old son is C5-6 complete, 2 years post injury. He not only suffers with total paralysis below his armpits, but debilitating neuropathic pain in his lower back, buttocks and down both legs. How can I get him into a rehabilitation program or one of your clinical trials that will help him regain some kind of Independence? All his doctors here in Phoenix Arizona have given him no hope whatsoever that he'll ever be able to leave his bed.
Dr Wise Young's contact details. Best wishes. keck.rutgers.edu/research-clinical-trials/faculty/57-faculty-person-1
clinicaltrials.gov/study/NCT03979742?term=spinal%20cord%20injury&rank=40&page=4&limit=10&tab=table
Brilliant video and very insightful, I have a c4 incomplete injury resulting in a rare condition called brown-sequard syndrome, I really want to get to contact dr wise and possibly get the stem cells done myself, as I can already walk I could go away and do the 6/6/6 program myself
Hi Ben, Thank you for your comments. May we suggest that you do that with the supervision of a qualified specialist in this area.
Seeing Dr wise young.
Gave a hope that I will be cured one-day surely 😊
I am from Nepal how can I get this treatment.
Please let me know
thank you for sharing, may i know how do i can get consultation with Dr Wise?
keck.rutgers.edu/research-clinical-trials/faculty/57-faculty-person-1
Where can we get this treatment?
Dr Wise
Please advise if you have an email or a link to get in touch.
Thanks
keck.rutgers.edu/research-clinical-trials/faculty/57-faculty-person-1
Hi, very interesting interview, I have Spinal Cord Injury and would like to find the clinical trial do you have a link to that. Im looking in clinical trials.gov and haven't found it. Thanks.
Hi Christopher, I have passed on your enquiry to Ira Pastor ideaXme exponential health ambassador, who interviewed Dr Young to see if he can reach Dr Young on your behalf to point you in the right direction. If we hear back - we'll be in touch. I am happy that you found the interview interesting and useful. For your information ideaXme interviews are also available in audio format on 10 audio platforms including iTunes and Stitcher, as well as here: www.radioideaxme.com. All the best, Andrea Macdonald, founder ideaXme.
Ira Pastor has asked us to forward this link to you - maybe you could contact Dr Wise Young via these details. All the best. keck.rutgers.edu/research-clinical-trials/faculty/57-faculty-person-1?fbclid=IwAR1YpUzb0V2vxBiPq1u-tRCVAJS1jK0eUZ1-DBX1ctm-D_OVGledsdc-n1c
@@ideaXme thank you for the information, I appreciate the help so very much!!! I have written to the address and waiting a reply. thank you again
@@christopher5360 Our pleasure! All the best and keep watching! Andrea Macdonald, founder ideaXme
Is their new info on the big research?
Can you explain how can a paraplegia person walk for 6/6/6
Is there a method or a graduate program that we can start on our on?
What's going on here Wise, is that your aligning the spinal cord with the pull of gravity, by encouraging exercise and walking. Even a swimming baths would afford this with good support for the patient. Such a shame you ignored results from Inclined Bed Therapy on your forum.
Hi Andrew, Thank you for taking the time to comment. We'll pass on what you have said to Dr Wise Young.
Can you provide more information about 6/6/6 training method?. How paraplegia patient can walk 6 hrs per day?.
Hi Santhosh, Ira Pastor has suggested that you try to reach Dr Wise Young to receive an answer to your question via the details in this link keck.rutgers.edu/research-clinical-trials/faculty/57-faculty-person-1 You can also listen to ideaXme interviews on 10 audio platforms across the internet including iTunes, Stitcher...and here www.radioideaxme.com With best wishes, Andrea Macdonald, founder ideaXme
Exactly
where can we track trial results?
Hi Ana, You can contact Dr Wise Young here
young@dls.rutgers.edu. All the best. Andrea Macdonald founder ideaXme
@@ideaXme THANKS!!!
Ana Peranic You are very welcome Ana!
I am sci patient
I would like to have an opinion on this reflection
IF ALL OF THIS HAS BEEN PROVEN:
• To create artificial neurons and / or generate biological neurons
• To create artificial synapses and generate synapses through mechanical or chemical stimuli
• To remove scar tissue by surgery or by administering a chondroitinase enzyme
• To read neural activity through artificial intelligence (even online, creating a hybrid brain)
• Reprogramming stem cells (embryonic, olfactory, or even laboratory-grown and composed of water)
• Administer cells without interacting directly with the spinal cord and which is safer and more effective.
• To create a 3D spinal cord
• To use a conductive polymer that adapts to organic and nervous tissue (PEDOT)
• Modify the protein responsible for healing using the revolutionary CRISPR CAS9 method
• Carry out allogeneic transplantation of reprogrammed cells taken from the hand of the same patient and which adapt to the brain tissue forming synapses (thus also avoiding clinical trials on animals, rejection and bypassing ethical issues)
• To use olfactory cells as they have a longer life span than other types of stem cells
• To create biocompatible neuroprostheses
WHY ARE THERE STILL PEOPLE SUFFERING FROM SPINAL CORD INJURY?
Check out nvg 291 mice walk
@@barbaradascalos4411 Thanks Barbara ✌️
Nerve Gen are starting trials..all based on Jerrry Silver's work..search his youtube talks