Sickle cell anemia - causes, symptoms, diagnosis, treatment & pathology

[@Luke-pk3rb]

This video is INCREDIBLY well made. I cannot get over how in-depth, informative, and factual it is while still managing to be so concise. Must have taken so long to make so well done to whoever did. I'd love a list of your sources if that is also possible.

[@ashleelarsen5002]

I agree, but what do we use sickles for anymore? Gen Z is only going to know what sickles are for this discussion, they should change it to "crescent moon" disease...

[@fidosa8382]

@@ashleelarsen5002 bruh we know what a sickle is 😭 hmar

[@dinogt8477]

Sickle cell

[@sa21539]

If only med school professors taught lectures like this

[@prathameshagrawal2437]

He himself is med school teacher biro

[@adnaansheik7553]

@Sameer Ahmed I agree with you bro. The ones in my Uni are so boring that you might wonder what the heck are we doing with our life and why we chose Medicine.

[@genuine_meteen9169]

Haha...so true, looks like most med schools professors byheart and spit in it in class Without logic.

[@someone-jl9fu]

professors in uni teach like shit they make me wanna kms

[@IsmbbailBb89]

it's not a professional way of learning even if it's simple you should read and be aware of every little detail , i wonder what the face of medicine with students like you

[@gpsrandhawa8117]

It was my Grade 12 final biology practical and my project was Sickle Cell Anemia. I watched this video a night before and it all went so good. The examiner was so impressed. Thank you 😊

[@snehas9639]

i am doing the same thing

[@the_cracker_boi_4926]

Lol mines 6th grade wow

[@malikgaming3655]

i have sickle cell anemia

[@sportnewstv2749]

@@malikgaming3655 me too, how are you dealing with your situation 😥

[@aishwaryasiva4514]

👏🏻👏🏻

[@ShikaTheGod]

I have Sickle Cell Anemia so I know this is on point, also I haven't had a SCA Pain Crisis since 2012 so hooray!

[@SlickEvan]

2012 wow! Nice work!!

[@alltalentsmediacrayz2798]

Honey which country are u or please inbox me thanks I need to talk to u

[@ShikaTheGod]

@@alltalentsmediacrayz2798 I'm in the US, Texas to be exact

[@alltalentsmediacrayz2798]

Wow dear

[@alltalentsmediacrayz2798]

Are u on watsup dear

[@docsanti8971]

WOW! Very well explained! Wish we had this kind of resources when I was at Med school. Well done!

[@faijumusic1599]

Check out my Sickle Cell Disease testimonials ❤️❤️❤️ Please subscribe to my channel!

[@otet2004]

😑 omg read the book is much details than this video a lot !! But what i love about the video is so brief and made easy

[@xsx_kingx]

Thank you so much this video helped me a lot I'm 15 and I'm trying to create a cure for sickle cell this video helped me get a lot of notes and I would love to text you and ask you some more questions

[@monoromo]

Good luck on curing it!

[@cristamundil6697]

What are you thinking? How’s it coming along? Don’t give up! That’s wonderful

[@kimeilacampbell2694]

Thanks! I wish you the best

[@everydayshad]

I would like the cure because I’m only 11 and I’m scared of death

[@45_dhruvpandya20]

Um I don't know if you're joking or actually serious.
You're 15 and anyone can use the famous Phineas and Ferb line of "Aren't you kids too young for all this ?"
But good luck to find the cure. I wish you success !!

[@BillieB.]

Very good video, I didn't come here to learn though because I unfortunately have sickle cell anemia. But I occasionally watch these videos when I'm dealing with minor pain as weird as that may sound it's comforting 😞

[@osmosis]

We hope that our video was able to help 🙏🏼

[@splendidmercy6567]

Thanks so much for the video

[@Bassman7608]

Just lost a good friend to a sickle cell crisis. This video has taught me more than I could have imagined and I hope I could pass this on to as many as I can

[@osmosis]

We're sorry for your loss, Kevin. 🙏🏼

[@Tanishdutt0007]

I watched Video of Renal Artery Stenosis and made my project of Class 11th And believ me My teachers were so impressed with me. They all appreciated me . But all thanks Goes to OSMOSIS, I LOVE ❤OSMOSIS

[@osmosis]

Wow! That's awesome! Thanks for letting us know, Mamta! 💕

[@Tanishdutt0007]

@@osmosis Yeah!! but that's my mom' name. My name is KRRISH, by the way I loved you replied me after reading my comment. ❤❤

[@anjalieabhayarathne6314]

This was just so amazing! I had no idea that sickle cell disease was THIS easy to understand. It was very very clear. And I love the attractive pictures. And the narration was so good as well. Thank you so much!!!! Keep up the good work! 😁❤

[@Afton_OnYoutube]

@Daron Brown Aye, I do too

[@patriciacole1117]

No one should born with sickle cell today get tested get tested before you marry or get into a relationship please 🥺

[@LSBUFU]

Incredible lecture for nursing students like me. Thank you!

[@milonmitra3584]

You presentation is excellent. I would like to add one point- the lifespan of normal RBC is 120 days but a sickle cell rbc's lifespan is 10-20 days. This cause increased destruction of RBC with anemia.

[@todotvstreaming]

I recently lost a good friend of mine because of sickle desease. She used to have treatment which helped her deal with this disease but she got vaccinated against COVID a few months ago and she started to have more frequent outbreaks. Really sad that she passed away so young, 34 years old. Seems the vaccine increased her risks due to this health condition. May she rest in peace. She was always smiling and happy despite all the pain this sickness caused her 😔

[@DavidJohnson-dc8lu]

You saying Covid vaccinations are bad for SC? Vaccinations does inflame the body!

[@keziahaddoquaye53]

I’m a 14 year old girl who has sickle cell disease that just wants to know more so thank you

[@cryptomom3170]

Love it!!

[@cryptomom3170]

Well I'm saying. Not that fact u have. I know what it brings my 16yr kld daughter has sc disease. It's just the fact that u want to know more!

[@cryptomom3170]

@Daron Brown stay strong! My daughter has SC disease she's not in & out the hospital as those with ss disease... But when she have episodes it's painful! Prayr to you all😘

[@keziahaddoquaye53]

Daron Brown stay strong 💪

[@vet5838]

@Daron Brown you are a WARRIOR! Praying for you always.

[@user-xu8pt6uy8h]

Whenever we need to learn full medical information with fun and short time Osmosis is here to help. Thank you Osmosis from all my heart. I am the first on my college because of u ♥️♥️🎓♥️♥️

[@osmosis]

Wow! Thanks for letting us know! Our pleasure to be of help in your studies! 🥰

[@mariaragonese2543]

I'm only here because one of my co-workers has sickle cell as well as one of my customers and I want to better service them. The man actually had jaundice and I had asked him if he was okay. He said he had sickle cell and outside of the fact that mostly black people and Native Americans get it I don't know much about it.

[@khushboogupta8083]

Your videos are really a great help in understanding​ the concepts.

[@gtgodbear6320]

I have to get for blood transfusion post-op from internal hemorrhaging after getting an appendectomy. Hemoglobin levels just kept dropping and dropping all night. I had to have an emergency surgery and 4 blood transfusions to fill me back up with blood. Doctors were baffled that I wasn't dead. They had to cut me open like an old-time discectomy to find the bleeding and vacuum out all the blood. I had a staple puncturing a small artery at the appendix removal site. Closest I've been to death. Good thing they chose to keep me overnight or I would have died if I was sent home.

[@fahadmunir892]

May I ask Please
Have you experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

[@BillieB.]

@@fahadmunir892 I have my friend, I also have SS

[@HolySteppaLM]

i got tested when i was younger and i passed but i'm getting tested next week again. This sucks but the lord says" i know the plans i have for declares the lord plans for welfare and not for evil to give you a future and hope" Jeremiah 29 11

[@Vestrix]

I have sickle cell anemia Beta, and i have to take penicillin, folic acid and hydroxycarbamide 500g capsules

[@somsangsi]

How are you? :((

[@somsangsi]

get well soon and stay hydrated 💛

[@Vestrix]

@@somsangsithank you so much, i will for sure

[@Vestrix]

@@somsangsi welp, im better, but i have to takes those for the rest of my life, but ive been doing fine

[@Vestrix]

@Pendulum theres no really first symptoms it was diagnosed when i was like just born

[@christinesalami7712]

Your videos are my savior in medical school ❤❤❤ lots of love
The most wonderful thing that happend in my medical journey is Knowing and learning from your videos love you a lot ❤❤❤❤❤

[@osmosis]

Our pleasure to be part of your medical journey, Christine! 🥰❤️🙏🏼

[@RohitPant04]

Thanks for always providing us with extra information on common BioMedical topics like this!

[@reginaopoku2203]

Splendid ! I'm a sickle cell carrier and this is very educative . God bless you. I'm watching you from Ghana. Wish you the best in life 🧬

[@osmosis]

Thank you 🙏🏼

[@halicarnassus8235]

Sickle cell is not even common in most black Americans , however I had a black American friend who was born with it and she described it as if "Fire running through her Veins". Such Pain. Such torture.

[@easymedicinebytmd8247]

Isn't it amazing that in heterogen allel situation this protects from malaria?

[@charmaineframe7382]

No. Not really.

[@user-wt6hw5mi5q]

Yes.

[@shamaz1d]

blessing in disguise

[@namrata9235]

It's the silver lining.

[@iamcrocodile3148]

It is amazing.

[@billrowe3350]

My beautiful strong wife has Sick cell God bless you all who share this illness our prayers to you warriors!!!!

[@fahadmunir892]

Hope she will get well very soon.

[@fahadmunir892]

May I ask Please
Have your wife experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

[@Carlos_Jzx]

I have this decease and men o men thanks for the great job on explaining this and this is the best explanation I have found yet!✌🏽

[@rajeshwarijessy7776]

Can u explain your symptoms while affected by this decease

[@Carlos_Jzx]

@@rajeshwarijessy7776
You really want to know.
It's very very detailed here I can't add more is a bit different to some of us on how affects you for example I move to the north east and I been here 16 years and the cold has started to bother me in ways I didn't experience before.🤷🏽‍♂️

[@cultclassicz]

@@rajeshwarijessy7776 I have sickle cell and a thing i notice is i cannot take full breaths, my heart races rapidly, and i syruggle to breath when sleeping or laying

[@nakayizaneema2264]

Sure?

[@oreskoul]

Great video . Well explained . Made it easy . Once again, thank you osmosis ! 🙏🏼

[@Sarahwilliam455]

I totally appreciate this Video, I'm in Nigeria and I was able to get hydroxyurea about two years ago which was really helpful but I've been finding it hard to see it in Pharmacies I'm Nigeria, Can you suggest how I can get this Medicine??🙏🙏 I'd appreciate a response Sir.

[@reaperofdeath8957]

It's nice to know more about the disease I have.

[@locallife9371]

I have 2

[@SeniorMM2024]

2+

[@srajan_shukla]

Could I please please get the pdf of this presentation.... 🙏🏻 🙏🙏🙏

[@theenglishfamily5375]

Well appreciated... We look forward to more understandable videos ❤

[@clarycluade666]

I was born as sickle cell I pass throughout a lot of pain I thought my life as come to an end. I lost all my hope until a friend recommend me to baba ifa. BABA IFA thank u for my life may God continue to bless ur good work. no more pain or crisis I'm free indeed,
U can so give him a try
All u need is to believe
[phone]

[@music_7735]

Simple ,clear and perfect explanation !!👏

[@osmosis]

Thanks, Suharshitha! 🙏🏼

[@23dayslater95]

Im having a crisis watching this. I just wonder why my pain is so bad 😫😖

[@guri9583]

😂 make sure you drink water

[@nasiahearts414]

23_Days_later same

[@TheMorrisonjamari]

I hope you get better I have it too

[@breakergirl47]

First of all you have to change your mind set, telling yourself that you are ok and healthy. Then start eating only healthy food, I mean things that came with creation. You have to be alkaline. Alkaline body , alkaline food. Your cell has mucus in it and it has hardened, once you clean your body my eating alkaline foods, no hybrids or man made, the mucus in your cell will become soft and leave the cell and you will be ok. There are herbs 🌿 to use along with the diet and these herbs work only in an alkaline body. No meat 🥩 and drink a lot of Spring water a day. All the best🤗

[@Tranquiboss123]

Same

[@binodadhikari5255]

How sickle cell disease causes osteomyelitis? Any idea plz

[@KhadeejaMansour]

absolutely helpful, thanks!!!

[@osmosis]

You're welcome, Khadeeja! 😊

[@hkhk1901]

I wish I had professors like you in university 🌟amaizing job

[@kevinsteel7875]

The editing and transitions are seamless, very nice very informative.

[@osmosis]

Glad you think so, Kevin! 💕

[@worldgreatempire]

I swear this is great!! Abt Medschool Professors... I suppose it's because we already have a background with Sickle Cell Disease is why it now appears easy... This will be difficult for a newbie! Unless revised over and over

[@osmosis]

Thanks! 💕

[@justrandom4304]

Is sickle cell in anyway related to the repetition of getting blood clots coz I have some kind of anemia I just realized that I might have a blood clot near my lungs its a sharp pain when i take a deep breath. I'm going to see a doctor ASAP

[@streets0ul943]

I did a health genetic and dna test and it shows that I may have sickle cell as it runs in my family which I did not know. I have never been told by a doctor that I have sickle cell but don't regularly go either. As a 41 yr old is it possible to never get diagnosed until later?

[@BillieB.]

While I'm not a hematologist, I do have sickle cell anemia (unfortunately), and I've had it since I was born, and the likelihood of you having SS is VERY slim because pain crises aren't a rare occurrence, and they happen often especially if you aren't on medication.
It's something doctors catch pretty much from birth! Not to mention the fact that the life expectancy for SS was around 19 to 20 years old, up until the early 2000s from my understanding. This may sound depressing but the likelihood of you being alive right now with no medication would be VERY low, I honestly don't think it would be possible.
Hope that helps just my experience and knowledge tho!

[@danielkq]

Hello from Brazil!

[@mtorabi6266]

Because of your perfect videos now I can learn and enjoy.thank u

[@JuliaHelen777]

Where on the axis of Hishimoto-Fybromialgia-MS-CFS-Parkinson do Sickel Cell Disease pass in & what might be the interrealtion?
What IF is all due to artificial syntetisation of biologic life?
Is there any open source study taking this points of view in consideration?
Where can I find more?

[@akashkamboj1270]

Sir this is the best video lecture I have ever seen
Wish my teacher could teach like you

[@sniyastanlyk7676]

Beautiful narration and presentation ❤.. Loved it ✌

[@osmosis]

Thanks a lot, Sniya! 😊

[@Stubborn214]

Hands down!
the best lecture on SCD!!
It was palatable ❤

[@osmosis]

Wow, thank you! ❤️

[@thathappymind6916]

Very helpful video ! Accurate and easy to understand

[@osmosis]

Glad you think so! 🥰

[@nabukhanal6519]

my dad at the age of 70 got diagnosed with this . He had dengue few month back since then he had been sick n tired

[@beautiful_nicole_3198]

This is scary my boyfriend go through this mostly all the time

[@BillieB.]

Stay strong I also have a sickle someone need me on you an amazing person for supporting you boyfriend! I know a lot of people that aren't willing to deal with people like me ☺️

[@hanrubuhrmann384]

This was a damn masterpiece

[@joang.5174]

Hello, good morning. Thank you so much for wonderful lecture/discussion. Your video so helpful to my course. I learn a lot, can I use some of your video like diagnosis,treatment etc. For my project? @Osmosis

[@osmosis]

Hi Joan! Glad that you find our videos helpful. You may reach out to [e-mail] and our team will be glad to assist you on your inquiry. 🙏🏼

[@alexanderksn2372]

Thanks a lot for your videos! Maybe it was worth paying more attention to prime editing or CRISPR Cas9 or Cpf1 as an innovative approach to treatment?

[@azoooooz25]

My professor taught this in 1.5 hours and you outed her in 8 mins

[@mariaalma6563]

Cramming for my midterms right now. This helps so freaking much. Thanks for existiiiing!

[@zackabdihakim2737]

Thanks. Very well prepared and presented.

[@livingdeadgirla]

1:24 I never knew that before watching this. Extraordinary.

[@aishwaryasiva4514]

I totally depend on osmosis only for viva sessions 😂
Examiners appreciated me 😎

[@jalilahmadtokhie7805]

Proud of osmosis production company

[@osmosis]

Thank you, Jalil! 🥰

[@gauri9319]

Chages shape that allows polymerization due to which it forms Cresent shape???... didn't understand...!!!!

[@yaya-fv9eg]

Thanks ❤❤

[@dikshashelar2508]

nice explain

[@fasamah.kollie8767]

Splendid ❤ demonstration. A well deserved hats off 🙏🏻😊

[@osmosis]

Glad that you appreciate it, Fasama! Thanks! 💕

[@semsem8801]

Thank you for all videos

[@munahiljaved2028]

Very well explained in a much comprehensive way!!

[@osmosis]

Glad you liked it, Munahil! 😊

[@user-yf4kj9jy8u]

My friend Sarah (that I have known since kindergarten) Has Sickle cell anemia. She says that is makes her small (which she is) And I hope it’s okay. She also said it makes you die at 50 - 60. And this really helps!

[@manuelmorales2413]

I'm sufferring a crisis right now on my left arm, I hate suffer this kind of pain frecuently 😢😥

[@manuelmorales2413]

@Nyla Davenport What is it recommended for?

[@zzs8948]

Amazing content indeed ! But the type of hemolysis in Sickle cell anemia is mostly extravascular and abit less intra as far as i know , thank alot

[@rahafabdelgafoor4002]

Some informations in the video are correct

[@ismailissifou2024]

this is awesome and really helpfull, but could you be able (or maybe any reader) tell me what source was used for this vid?

[@mahimasreehari6216]

It's really very helpful, i was literally confused but thanks to you I got it now . Thank you very much ☺

[@legends-og5dx]

Ok

[@zaidbasheer9152]

I was almost giving up until I saw this vedio ❤ Thank you very much

[@osmosis]

We're glad this helped, Zaid! ❤️

[@omnaik5539]

Thankyou for this important information

[@VampireDiariesBiebs]

cant thank you guys enough!

[@SALMA-mq2os]

You always save my brain from any additional requirements 😇 thanks

[@osmosis]

Happy to help! 🥰

[@waleedkhalid6908]

Thanks for your wonderful efforts

[@dr.rohanparmar10]

please provide more information regarding types... beta zero / beta Plus Thal sickle

[@osmosis]

Thanks for your recommendation, Rohan! Our team will be taking this into consideration. Have a lovely rest of the week! 💖

[@estiakshakil2663]

Excellent explanation...❤️

[@osmosis]

🥰❤️🙏🏼

[@DermNerd808]

Jaundice is skin yellowing?

[@basharawwad7709]

Yes getting pale

[@abdullahmunir1994]

not only skin yellowing many more other key sign and symptoms to declare as jaundice

[@justineclark5775]

Wonderful video. Thank you.

[@minaazeez1311]

That was very helpful. Thank you.

[@osmosis]

Glad it was helpful, Mina! 💖

[@manikandanbalakrishnan3373]

Have Avascular Necrosis, and having same symptoms of sickle cell disease

[@drlenton1746]

thanks this is great workout in few minutes

[@osmosis]

Most welcome! 💕

[@Jeene269]

Thanks for the good explanation ✨

[@osmosis]

You’re welcome! 😊

[@BA-vc9wh]

Very wonderful and informative presentation 👏 👍

[@osmosis]

Thank you! Cheers! 😊

[@btsloverkpop6500]

sickle cell anmeia is treated by physical or chemical method ??? give me answer i have paper so plz tell me answer of this

[@srirambhardwaj2343]

Very.helpful.lecture.

[@k1ngkanna568]

I think I just figured out the way to cure this. So since sickle cell is caused by a mutation in the Hemoglobin cell, we can actually find a type of medicine that takes pieces from immature blood cells and uses them to reconstruct mature ones. To make this we can piece together a modified blood cell, if we use this I want it to be green, and the thing we can do with that is make it behave as if it is like a blood cell surgeon, or so I said. Basically what it would do is take immature blood cells, take pieces of those cells, and use the sickle cell's property of sticking to things to piece it back together. As for the defective Hemoglobin, we could inject new mature blood cells with non defective HGBN and basically program the green blood cell to take the good Hemoglobin and give it to a sickle cell.
P.S: I AM 12 YEARS OLD AND I FIGURED IT OUT HOW DID NOBODY THINK OF THIS????

[@MonkeyMan-co9io]

They most likely have but usually the method of changing (injections, pills, etc) as well as testing for quality / side effects is a another complication

[@morrenmbilinyi3545]

Really thanks you,that was so helpful

[@osmosis]

You're welcome! 🥰

[@AlexandraAbia]

Thank you, very informative!

[@justsomeguywithsunglasses3661]

Incredible presentation!

[@nolapender9239]

This video helps me a lot for my tomorrow’s presentation about sickle cell anemia in rle109

[@nozomiyomi1039]

Wow thank you osmosis.

[@sumathybalaji5252]

Very nice explanation

[@Rene-uz3eb]

The good thing about hydroxyurea, at the 25mg/kg or so daily dose and up it is a strong iron chelator so on the side should cure and prevent pretty much any cancer out there (over time, if adhering to daily doses, about as long until you see the hbf and higher hb kick in, but I would guess no more than 5 month until cancer starts shrinking)

[@neisha4045]

What is the reason for leukocytosis in SCD patients? Is this as a result of extramedullary haematopoieses?

[@rubasarkez9917]

Well done thank you so much 👍🏻👍🏻

[@belanabdulla6368]

Very helpful, thanx.

[@dgbrfe]

I used to have sickle cell but it was different. So when i was at school at recess i could’t go outside to play and i had to stay inside to play but good thing i don’t have it anymore.

[@Tranquiboss123]

How did u got rid of it

[@ryancrump7887]

Samarth what kind of herbal med

[@samuelsundaysaviye1469]

@@Samarthhpaisings Hey , I have Sickle Cell, Could you please let me know which herbal doctor this is? Or which herbs I can take?

[@samuelsundaysaviye1469]

Hey i have Sickle Cell, how did you cure it?

[@dgbrfe]

Well idk. You should ask doctors.

[@user-ve5wx9lz8g]

Well appreciated on well explain lectures

[@osmosis]

So nice of you! Thanks! 🥰