Post-Transcriptional Modifications of mRNA

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  • เผยแพร่เมื่อ 4 ก.ย. 2014
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ความคิดเห็น • 106

  • @Baluwa_
    @Baluwa_ 5 ปีที่แล้ว +34

    You must know you have saved my med school life.

    • @valeaves
      @valeaves 4 ปีที่แล้ว +2

      Cynthia Mali Mine too!

  • @AngelA-bb5jl
    @AngelA-bb5jl 7 ปีที่แล้ว +77

    Dude I wish I had you as my professor. God Bless

  • @junaidhasan8215
    @junaidhasan8215 8 ปีที่แล้ว +57

    you might just save me from failing my biochem test on transcription and translation. There's no time left to read books so i resorted to listening your lectures, the decision i'll never regret. You have given me hope. Thank you! Keep up the good work!

    • @saadrehman362
      @saadrehman362 5 ปีที่แล้ว +4

      How did you do on the test?

    • @quintonwilson8565
      @quintonwilson8565 3 ปีที่แล้ว +5

      Transcription in AP Bio, transcription in microbiology, transcription in genetics, transcription in molecular biology, transcription in biochemistry, UGH!!!!!!!!!!!!!!

  • @emilygreen2436
    @emilygreen2436 8 ปีที่แล้ว +6

    You are amazing. Thank you so much. I literally wouldn't get through my studies without you.

  • @Matt-re4et
    @Matt-re4et 7 ปีที่แล้ว +3

    I really enjoy the videos, especially the fact that everything isn't shoved into one video but a series of videos. I'm only in gen. bio. 1 but this is very helpful.

  • @123youareafruitcake
    @123youareafruitcake 8 ปีที่แล้ว +11

    Why doesn't this have more views?? This is great!!

  • @samanthachiwashira2942
    @samanthachiwashira2942 4 ปีที่แล้ว +3

    Two minutes into the video and wow youre really good at explaining!

  • @tsiontaddese2813
    @tsiontaddese2813 5 ปีที่แล้ว +3

    these videos are right on. You saved me so much time and energy. God bless you!!

  • @ramaalomar3084
    @ramaalomar3084 2 ปีที่แล้ว +2

    you are amazing! you know exactly how to explain, and from which points you should start and finish. Thank you a lot!

  • @acvz1145
    @acvz1145 8 ปีที่แล้ว +2

    Thanks so much for these videos!! You are a great teacher, and are great at explaining these processes. You are saving my genetics grade!! :D

  • @rayanallehaibi9498
    @rayanallehaibi9498 8 ปีที่แล้ว +16

    U r amazing in conveying the information

  • @lawyerdoctor
    @lawyerdoctor 5 ปีที่แล้ว +3

    Your videos are amazing, Thank you, thank you, thank you!

  • @hanasehans8502
    @hanasehans8502 5 ปีที่แล้ว +4

    you are so underrated omg this is so good

  • @kiimi1614
    @kiimi1614 4 ปีที่แล้ว

    Thank you SO MUCH, you're videos are so helpful! GOD BLESS YOU

  • @kanzadoll7285
    @kanzadoll7285 7 ปีที่แล้ว +3

    Thank u .... ur vidios really help me to get excellent scores in exams by just getting concept than cramping☺

  • @ayeshaparveen7597
    @ayeshaparveen7597 4 ปีที่แล้ว +1

    Omg you are the best the way you explain every single thing with patience is amazing and you made these topics so easy😁 Thank you 🙏

  • @ayeshajabeen6557
    @ayeshajabeen6557 4 ปีที่แล้ว +1

    Sir u are just great.my all the concepts become clear through your lecturs .

  • @huilee186
    @huilee186 7 ปีที่แล้ว +2

    thanks for making such a great post. it saved me a lot of works. have subscribed the channel and please keep it up

  • @edmundmigwi5579
    @edmundmigwi5579 3 ปีที่แล้ว

    You've just saved my semester

  • @llennzo
    @llennzo 22 วันที่ผ่านมา

    Exons are expressed intros are in the way. This is a great phrase.

  • @adsingh54321
    @adsingh54321 7 ปีที่แล้ว +1

    thank You so much Andrey !!!
    sir this video is very HELPFUL

  • @davidfell9696
    @davidfell9696 8 ปีที่แล้ว

    Another excellent explanation!

  • @zeevgolin2984
    @zeevgolin2984 7 ปีที่แล้ว

    Great videos and very informative !
    Thank you.

  • @abramovicsta8434
    @abramovicsta8434 8 ปีที่แล้ว +2

    Absolutely perfect thank you very much

  • @mohammedal-hammadi5085
    @mohammedal-hammadi5085 4 ปีที่แล้ว

    I appreciate your efforts really, so great lectures, thank you so much

  • @dayanjisherpa3548
    @dayanjisherpa3548 2 ปีที่แล้ว

    You guys are very good in explaining. Love from India

  • @samirgeorges2686
    @samirgeorges2686 7 ปีที่แล้ว +1

    Absolute masterclass

  • @maryamahmadij.6752
    @maryamahmadij.6752 2 ปีที่แล้ว

    Did you know that you are such an amazing teacher?!!!! ^___^

  • @sandhyakumari9038
    @sandhyakumari9038 3 ปีที่แล้ว

    Thank you sir your all videos are so helpul..clear nd easy to understand ..complex topics

  • @tonuinicholus6395
    @tonuinicholus6395 6 ปีที่แล้ว +2

    Thank you. I really appreciate your effort in explaining these concepts.

  • @fjshepherd1
    @fjshepherd1 7 ปีที่แล้ว

    so helpful but had to watch 5 times cause kept fantasizing about you and I together

  • @smithajohns77
    @smithajohns77 6 ปีที่แล้ว +3

    what a nice teaching""""

  • @hamedhosseini4938
    @hamedhosseini4938 7 ปีที่แล้ว +1

    God bless!

  • @mostafaali8108
    @mostafaali8108 7 ปีที่แล้ว +2

    thanks.very helpful videos

  • @andellahypolite
    @andellahypolite 7 หลายเดือนก่อน

    Clear and Succint! Thank you

  • @renoreno8755
    @renoreno8755 2 ปีที่แล้ว +1

    Great explanation
    Thank you

  • @sahanahn19
    @sahanahn19 4 ปีที่แล้ว +1

    Sir I wish u would be my professor 👨‍🏫. U teach so well sir.. Thank you so much..

  • @manushoganyan6302
    @manushoganyan6302 8 ปีที่แล้ว

    Thank you so much! Very helpful!

  • @motivationtostrive1216
    @motivationtostrive1216 ปีที่แล้ว

    God bless you for saving me and the rest of us you are so underated God bless 🙏🙏

  • @astro8149
    @astro8149 8 ปีที่แล้ว +3

    THIS HELPED ME SO MUCH

  • @prathyushasrinivas5008
    @prathyushasrinivas5008 8 ปีที่แล้ว

    thank you !
    it was very helpful

  • @kanikabhardwaj7719
    @kanikabhardwaj7719 7 ปีที่แล้ว +1

    thks for clearing thoughts

  • @YusufHassanConsulting
    @YusufHassanConsulting 6 ปีที่แล้ว

    You are the best!!!!!

  • @mohi7527
    @mohi7527 ปีที่แล้ว

    Thanks. I wish you were my professor.

  • @carolinemangare3071
    @carolinemangare3071 7 ปีที่แล้ว

    Great job

  • @BioAffairs
    @BioAffairs 6 ปีที่แล้ว

    wow sir detailed information

  • @epicmoments1964
    @epicmoments1964 ปีที่แล้ว

    Well explained. Thanks🙏

  • @goldenboy886
    @goldenboy886 8 ปีที่แล้ว +1

    Thanks

  • @inesgonzalez2246
    @inesgonzalez2246 2 ปีที่แล้ว

    Awesome lecture 👌

  • @dsg003
    @dsg003 8 ปีที่แล้ว

    Great!!

  • @catherinsebastian8162
    @catherinsebastian8162 3 ปีที่แล้ว

    You must know dear 🤝🏻 You are Just Awesome 💕🙌🏻God bless🧚🏻‍♀️

  • @nonskiieee8511
    @nonskiieee8511 3 ปีที่แล้ว

    thank youuuuu

  • @sarveshamrute568
    @sarveshamrute568 6 ปีที่แล้ว

    Thank you so much sir...😊

  • @slimanelamia3225
    @slimanelamia3225 3 ปีที่แล้ว

    Thank you so much sur.

  • @zahraaalkhalisi3501
    @zahraaalkhalisi3501 10 หลายเดือนก่อน

    Perfect

  • @crickethub8708
    @crickethub8708 6 ปีที่แล้ว

    Great sir

  • @nada.h.majeed
    @nada.h.majeed 3 ปีที่แล้ว

    Thanks brother 🌼

  • @thereal7490
    @thereal7490 5 ปีที่แล้ว +2

    good explanation as usual
    but the process of splicing is quite complicated and needs to be explained with some more detail
    thank you

  • @jubamark4851
    @jubamark4851 6 ปีที่แล้ว

    Thanx ak

  • @user-uc5rx4vp7j
    @user-uc5rx4vp7j 4 ปีที่แล้ว

    you are great

  • @michaellouis4882
    @michaellouis4882 7 ปีที่แล้ว

    I have a question. on the last part of splicing the exons, you mention about the poly(A) tail also spliced in the nucleus. And it is also mentioned before that, poly(A) tail aids in the transport of mRNA across the nuclear membrane. So, my question is why the poly (A) tail is spliced if it actually aids in the transport? or is it because its long structure is degraded gradually during the travel? Thanks in advance.

  • @instastoriesnupdates3080
    @instastoriesnupdates3080 3 ปีที่แล้ว +1

    Keep it up sir

  • @naomimacharia5609
    @naomimacharia5609 5 ปีที่แล้ว

    Thankyou...

  • @Kyrani99
    @Kyrani99 5 ปีที่แล้ว

    Thanks Good lecture, good explaining. Just please make writing bigger and don't put so much on the screen at once. It makes it very hard to read even on a full screen setting.

  • @mpc7440
    @mpc7440 ปีที่แล้ว

    One little nit-pick, on the diagram of the pre-mRNA, the introns look relatively small compared to the exons. In reality, introns tend to be far longer than exons (I say "tend" because their size varies). Again, just a nit-pick that I think is worth mentioning.

  • @malikid1000
    @malikid1000 7 ปีที่แล้ว

    Good explanation but would have been better if you mentioned the enzymes involved in each step.

  • @liopolt0915
    @liopolt0915 9 ปีที่แล้ว +2

    Thx for video, it helps me a lot :)

    • @AKLECTURES
      @AKLECTURES  9 ปีที่แล้ว +1

      Reza Pratama Nugraha you're welcome! :)

    • @mmaking8664
      @mmaking8664 7 ปีที่แล้ว

      Can you please describe a coherent order in which to watch your videos, like what to watch before watching another video?

    • @MrShaiiix
      @MrShaiiix 7 ปีที่แล้ว

      AK LECTURES very helpful concept

    • @MrShaiiix
      @MrShaiiix 7 ปีที่แล้ว

      Shallu Chauhan thnxx a lot

  • @lucygomango899
    @lucygomango899 3 ปีที่แล้ว

    Tq sir.....🙏🙏🙏💐💐💐

  • @aleynaa3420
    @aleynaa3420 7 ปีที่แล้ว +1

    can you tell me in what order these processes happen? is it the order you explain in the video? Excuse my English i know it is not good :)

  • @drevon2316
    @drevon2316 3 ปีที่แล้ว

    god bless uuuuuuu love

  • @colmmcgurk3742
    @colmmcgurk3742 7 ปีที่แล้ว +1

    I could be wrong , but i think you've made a mistake here. The exons are actually the coding regions for proteins! Introns are in fact the non coding regions!

    • @mavzai9800
      @mavzai9800 7 ปีที่แล้ว +2

      7:51 Nope

    • @geetamahar9940
      @geetamahar9940 5 ปีที่แล้ว

      Listen carefully ....thats exactly what he said...he is very clear abt what he teach..

  • @Indianintrovert
    @Indianintrovert 3 ปีที่แล้ว

    Basics♥️

  • @adyanwains8443
    @adyanwains8443 6 ปีที่แล้ว

    I have read many books for this question.but one book writer write first splicing then add caps and tail?

  • @leomiller2291
    @leomiller2291 11 หลายเดือนก่อน

    GOAT.

  • @dyoomah17
    @dyoomah17 9 ปีที่แล้ว +1

    Thanks alot 😊 .. what is the thing that is responsible for adding the cap and tail ?

    • @AKLECTURES
      @AKLECTURES  9 ปีที่แล้ว +1

      You're welcome! Not sure if there is a specific name for that complex but its basically a collection of different proteins and factors that work together to add the poly A tail and cap.

    • @jamesfleming4525
      @jamesfleming4525 9 ปีที่แล้ว

      dyoomah17 Cleavage and polyadenylation specificity factor

    • @malikid1000
      @malikid1000 7 ปีที่แล้ว

      The methyl transferase is the enzyme which adds the methyl group basically the cap on the 5 prime end. The polyadenylation occurs through binding of cleavage stimulatory factors which recruit cleavage factors which cleave the mRNA. The poladenylations then begins with the addition of adenine residues by poly A polymerase (PAP).

  • @AlanRasoulMentor
    @AlanRasoulMentor 8 ปีที่แล้ว

    hi du have any vedes on chemistory from beginning because am rubish with molecules and bonding stuff, i wanna start from the begging of understanding atoms, thanks

  • @mazurutazviwana1757
    @mazurutazviwana1757 9 ปีที่แล้ว

    good

    • @AKLECTURES
      @AKLECTURES  9 ปีที่แล้ว +1

      Mazuru Tazviwana Thanks!

  • @ChristianKekula
    @ChristianKekula 9 หลายเดือนก่อน

    I have a topic to discuss in class, this is the topic post transcription modifications

  • @adyanwains8443
    @adyanwains8443 6 ปีที่แล้ว

    HY! I have a question.u said splicing occur after adding caps and tail.but i said splicing before occur then add cap and tail.basically cap meaning protect if splicing after capping occur then cap not protect mRna?am i right or not?plz answer my question.thanks

  • @playagamelp2441
    @playagamelp2441 3 ปีที่แล้ว

    Why do I have to complicated stuff like this in high school? 💀 thx for explaining

  • @ChristlBolongaita
    @ChristlBolongaita 3 ปีที่แล้ว

    4:35 Screenshot!

  • @vikkramvenkatesan8656
    @vikkramvenkatesan8656 ปีที่แล้ว

    Hello sir is that possible to attach your notes in comment section

  • @sudeepbiswas6309
    @sudeepbiswas6309 8 ปีที่แล้ว

    by which the introns are made of??? where it differs from the exons thats why they cant code for translation....???

    • @venomart4768
      @venomart4768 7 ปีที่แล้ว

      Sudeep Biswas they basically not going to b translated into a protein. examples of introns are tRNA and rRNA

  • @DJSoCA
    @DJSoCA ปีที่แล้ว

    Isn't is amazing how humans have the cognitive ability to learn how humans (and other organic beings) work lol.

  • @tpatnight
    @tpatnight 5 ปีที่แล้ว +1

    2:06 screenshot

  • @shashvatanjani4432
    @shashvatanjani4432 ปีที่แล้ว

    Sir please I am so canfution yor voice please use simple and clin voice

  • @ronr.53400
    @ronr.53400 3 ปีที่แล้ว

    i wish i were this dude 😚 ALL THESE WOMEN GIVING HIM the thumbs up 🥰 👍

  • @blockbyblock4078
    @blockbyblock4078 4 ปีที่แล้ว +3

    no doubt he is great at teaching but why does he pronounce "Process" the way he does it ? It's weird ;)

    • @GeneticsLessons
      @GeneticsLessons 2 ปีที่แล้ว

      because he is originally from Russia as far as I know.

    • @blockbyblock4078
      @blockbyblock4078 2 ปีที่แล้ว

      @@GeneticsLessons Oh! I didn't know that. Makes sense now

  • @1024DS
    @1024DS 4 ปีที่แล้ว

    THEEK he chuu p