Cystic Fibrosis and the Mucociliary System

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  • เผยแพร่เมื่อ 26 มิ.ย. 2024
  • Cystic Fibrosis is a genetic disease that results in clogged and infected airways, malnutrition, and very salty sweat. Most people with this disease only live up to 40 years old. Curious as to why these symptoms and shorter lifespan occur? You've come to the right place - Medicurio is video series that will explain the pathogenesis, or the mechanism, of many common diseases. New videos come out every other Wednesday.
    For more information about cystic fibrosis or donate to its research, check out:
    Cystic Fibrosis Canada: www.cysticfibrosis.ca
    Cystic Fibrosis Foundation: www.ccf.org
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ความคิดเห็น • 102

  • @dhwani97
    @dhwani97 6 ปีที่แล้ว +27

    THANK YOU!! finally something understandable.

  • @nero91
    @nero91 7 ปีที่แล้ว +25

    Sub from a med student :D keep em coming, this is gold

  • @ETaroonie
    @ETaroonie 7 ปีที่แล้ว +11

    Thank you so much for this, there's a huge lack of information explaining how certain diseases result in their set of symptoms. I really look forward to more videos like this :) subbed.

  • @vzilqz3555
    @vzilqz3555 ปีที่แล้ว +1

    I was SO confused about this topic at first but this video made everything nice and clear , thank you so much

  • @CFlifestyleFoundation
    @CFlifestyleFoundation ปีที่แล้ว

    Thank you for making this video, and for helping spread awareness of this rare disease.

  • @hazemeid01
    @hazemeid01 3 ปีที่แล้ว

    Finally I understand CF properly
    THANK YOU!

  • @Swellnesss
    @Swellnesss 7 ปีที่แล้ว +3

    I know this sort of thing isn't especially engaging for a person unaffected by the condition, not taking a class involving these mechanisms, or someone not in a related field...but as someone of none of those, I really enjoyed the video. This is the sort of channel I can see growing! Like when you see massive edutainment channels with amazing graphics...they started out with complicated concepts made entertaining by a common digestible thread...entertainment. This was entertaining.

  • @an8778
    @an8778 7 ปีที่แล้ว +3

    Perfect. Looking forward to more vids.

  • @HackerxCAs
    @HackerxCAs 7 ปีที่แล้ว +2

    Another sub from a medical student. Very informative please keep them coming :)

  • @cariboowho
    @cariboowho 7 ปีที่แล้ว +1

    Excellent video! Keep up the good work!

  • @norainiazhar5298
    @norainiazhar5298 5 ปีที่แล้ว

    the best explanation about CF. Thanks!

  • @fluffyhoovy9108
    @fluffyhoovy9108 6 ปีที่แล้ว +2

    Great video, i no longer need to explain to everyone what it is great love it.

  • @Sherirose1
    @Sherirose1 6 ปีที่แล้ว +2

    Wow your vidoes are brilliant so far. Thank you.💕💕

  • @afc_zanzoon9887
    @afc_zanzoon9887 2 ปีที่แล้ว

    Insanely good video.

  • @memberHD
    @memberHD 7 ปีที่แล้ว +3

    love your work

  • @korabeka501
    @korabeka501 5 ปีที่แล้ว +1

    thank you so much that was way easier and straight forward

  • @TenDividedBySix
    @TenDividedBySix 6 ปีที่แล้ว +46

    TierZoo sent me here :) great video

    • @dinex8705
      @dinex8705 5 ปีที่แล้ว

      THX very much so useful

    • @alextortugo
      @alextortugo 4 ปีที่แล้ว

      Same

    • @azharhussain4278
      @azharhussain4278 3 ปีที่แล้ว

      @@dinex8705 drama

    • @marleycolin954
      @marleycolin954 3 ปีที่แล้ว

      pro tip: watch series at Kaldrostream. I've been using it for watching lots of of movies these days.

    • @kashkingston7296
      @kashkingston7296 3 ปีที่แล้ว

      @Marley Colin definitely, been using Kaldrostream for years myself :)

  • @victorferraz6782
    @victorferraz6782 3 ปีที่แล้ว +1

    omg this explication was soooooo good, extremelly clear and objective

  • @tuip1167
    @tuip1167 5 ปีที่แล้ว

    Amazing video! Thank you!

  • @p3nglin
    @p3nglin 7 ปีที่แล้ว +2

    Reddit brought me here!
    This is really cool man, thanks for this. Please keep it up! I found it super interesting.
    Is there any chance you'll be doing one on Eczema?

  • @grantleishman6900
    @grantleishman6900 7 ปีที่แล้ว

    Awesome video dude!!! Can't wait for the next one!

  • @cassimatchia9321
    @cassimatchia9321 2 ปีที่แล้ว

    This video has helped me in my university presentation in ways you can never begin to comprehend. Thank you so much my good sir

  • @PreetiGupta-lr7nh
    @PreetiGupta-lr7nh 3 ปีที่แล้ว

    Brilliant explanation. Thankyou🙂

  • @wesleytocool
    @wesleytocool 7 หลายเดือนก่อน +1

    Thank you! Med student here and you saved me so much stress and time!

    • @LOL_MANN
      @LOL_MANN 3 หลายเดือนก่อน

      I am not even med student and learn this shi for fun lol

  • @HB-zr4ep
    @HB-zr4ep 7 ปีที่แล้ว

    I'll support you mate. keep it up.

  • @shabnam_sajida
    @shabnam_sajida 4 ปีที่แล้ว

    Made the concept so clear

  • @ToxicCoworker
    @ToxicCoworker 7 ปีที่แล้ว

    I want to see this fleshed out. Do more, many more, the practice will make this great.

  • @joweenie9224
    @joweenie9224 6 ปีที่แล้ว

    this is a really good video, the visuals made it very easy to understand the concepts :)

  • @peoplecanbestupid
    @peoplecanbestupid 7 ปีที่แล้ว

    That's really awesome, subbed

  • @dragonmares59110
    @dragonmares59110 7 ปีที่แล้ว

    Nice video ! Can't wait to learn more !

  • @rajshreemeena9316
    @rajshreemeena9316 3 ปีที่แล้ว

    Thanks, great video
    Really helpful 😊

  • @poojakumari-qx2zu
    @poojakumari-qx2zu 3 ปีที่แล้ว

    The perfect explanation 👍

  • @christophercasanova3664
    @christophercasanova3664 2 ปีที่แล้ว

    Please upload more. Thank you.

  • @sbeen434
    @sbeen434 7 ปีที่แล้ว +1

    Earned my subscription ;) great video man! Would recommend that you purchase a good microphone like the Blue Yeti

  • @aaronlam6915
    @aaronlam6915 5 ปีที่แล้ว

    Great video!

  • @gavinturso2831
    @gavinturso2831 7 ปีที่แล้ว

    Great video! Keep it up!

  • @zannatul23
    @zannatul23 3 ปีที่แล้ว

    That was fantastic!

  • @aarush800
    @aarush800 3 ปีที่แล้ว

    great video

  • @mdfaruk-ml6vx
    @mdfaruk-ml6vx ปีที่แล้ว

    O my god .......too much good explanation

  • @joshuabanjo6639
    @joshuabanjo6639 3 ปีที่แล้ว

    Flawless; thank you

  • @Millzyof91
    @Millzyof91 7 ปีที่แล้ว

    subbed, great videos, keep it up.

  • @faihanaseem2984
    @faihanaseem2984 5 ปีที่แล้ว

    Very helpful

  • @sanjaisrao484
    @sanjaisrao484 3 ปีที่แล้ว

    Thankyou very much

  • @khush0726
    @khush0726 3 ปีที่แล้ว

    Awesome explanation... 🤓

  • @rafaelll.4778
    @rafaelll.4778 7 ปีที่แล้ว +2

    subbed! Do more till you succeed!

  • @mariociencia12
    @mariociencia12 3 ปีที่แล้ว

    Fantastic! Incredible! Amazing! Wonder! Super!

  • @syedmedicose7477
    @syedmedicose7477 3 ปีที่แล้ว

    excellent sir

  • @aishwarya1182
    @aishwarya1182 3 ปีที่แล้ว

    Great video 👏🙌

  • @chandanam7296
    @chandanam7296 6 ปีที่แล้ว

    Excellent

  • @rencewelltube
    @rencewelltube 6 ปีที่แล้ว

    Good stuff

  • @bushrashoaib3751
    @bushrashoaib3751 3 ปีที่แล้ว

    More videos please

  • @diyar2719
    @diyar2719 ปีที่แล้ว +2

    Thank you for this amazing clarification …
    If u don’t mind
    I used the (animations in this video : I screen recorded them 🙂)in my slides about cystic fibrosis for educational purpose in my country (Iraq)and we want to post it in TH-cam
    In our language(mostly)
    I just wanted to let you know 😊

  • @Zince
    @Zince 7 ปีที่แล้ว +2

    quite interesting, just hope you had a better mic

  • @crafterlula1328
    @crafterlula1328 7 ปีที่แล้ว +1

    This is awesome =D

  • @ahmadal-natsheh6814
    @ahmadal-natsheh6814 ปีที่แล้ว

    thank you so much i understood everthing about Cf >> thannnnk you

  • @rossheintzkill4848
    @rossheintzkill4848 7 ปีที่แล้ว

    Great video, very informative. Maybe a prognosis toward the end?--I know the mortality rate is unfortunately high, but don't know details.
    You said on Reddit this is a new series -- good luck! This was informative and interesting. The pacing could be accelerated.

    • @TheLivingBreathingWendy
      @TheLivingBreathingWendy 7 ปีที่แล้ว

      Ross Heintzkill That's actually a pretty complicated topic. Especially with recent medical advancements. This disease affects each individual VERY differently.

  • @mikagarzon342
    @mikagarzon342 3 ปีที่แล้ว

    wow i finally undestand it.

  • @khushalbakht3139
    @khushalbakht3139 3 ปีที่แล้ว

    Great yar

  • @trevorpeddie1647
    @trevorpeddie1647 2 ปีที่แล้ว

    how did you do it can you share with me , thank you

  • @emmasouthorn1137
    @emmasouthorn1137 4 ปีที่แล้ว

    I am 11 years old I have been diagnosis cystic fibrosis when I was two or one the doctors not explain a lot info that you just gave me because they did not want to worry me thank you for helping me understand for my condition I no longer have to share with my classmates what cystic fibrosis is because I can just show them this video thank you

    • @Medicurio
      @Medicurio  4 ปีที่แล้ว

      Emma, I'm so glad my video can help you! I wish you all the best and I hope better and better treatments for cystic fibrosis will be made for you.

  • @AWayOfLiving84
    @AWayOfLiving84 4 หลายเดือนก่อน

    I'm hopeful that I will naturally heal

  • @AWayOfLiving84
    @AWayOfLiving84 4 หลายเดือนก่อน

    I ran out a couple of days ago

  • @oll820
    @oll820 7 ปีที่แล้ว +28

    Great but you need a new better mic

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว +14

      Icetearz just bought a new one, the next video will have better quality.

    • @oll820
      @oll820 7 ปีที่แล้ว +2

      great :)

    • @Juzproo
      @Juzproo 7 ปีที่แล้ว

      Icetearz n

    • @aaronlam6915
      @aaronlam6915 5 ปีที่แล้ว

      Yay!

  • @rubycashell9859
    @rubycashell9859 7 ปีที่แล้ว

    I'd suggest better audio but nice info overall.

  • @AWayOfLiving84
    @AWayOfLiving84 4 หลายเดือนก่อน

    Emma constantly says I look pale. I say that's because of lack of oxygen. Then it worries her. But what can we do. The government has taken away most of opportunities to become a healthier person

  • @TheLowey2002
    @TheLowey2002 7 ปีที่แล้ว +1

    Thanks for this. My Grandma had Cystic Fibrosis and was told she wouldn't live to be 20 but lived to 60 and up to now the only thing I new about it was it had something to do with mucus in the lungs. I've been told I am a carrier (male) and I was wondering if you could explain what this means for any children I have in the future..

    • @theslashbro4474
      @theslashbro4474 ปีที่แล้ว +1

      You should probably get genetically screened. It'll help you calculate the probability of having children with CF. There's a bunch of genetic counsellors too that can assist you with the process.
      It'll also prove useful for the pregnancy process - as carrier testing can help you decide to get pre-natal testing which will help you decide what to do with the foetus if it does test positive for CF.

  • @user-fr9op9zb5j
    @user-fr9op9zb5j 3 ปีที่แล้ว

    You are greeeeeeeeeet😘😘

  • @baldgh0st594
    @baldgh0st594 ปีที่แล้ว

  • @hmartinez91
    @hmartinez91 6 ปีที่แล้ว

    It could also be paced just a little faster

    • @Medicurio
      @Medicurio  6 ปีที่แล้ว +1

      Thanks for the suggestion!

  • @runetoons2267
    @runetoons2267 7 ปีที่แล้ว +2

    Sub from a microbiologist :)

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว

      Thanks for the support!

    • @smiptr
      @smiptr 7 ปีที่แล้ว +2

      This content is fantastic. With the end portion about global susceptibility- theres evidence to suggest that faulty CFTR actually provides immune resistance against typhoid because the pili can't attach to the mutated CFTR, cholera resistance because the faulty CFTR won't pump out ions and water so you don't get watery diarrhoea and TB resistance down to disruption of Chloride homeostasis -> reduced ARSB -> reduced hydrolysis of sGAGs -> reduced levels of sulphate available to Mycobacterium tuberculosis, which it needs in its cell wall for virulence
      meaning Cholera, TB and Typhoid could have all been selective pressures for high CFTR mutation in Europe!
      The play off between the more deadly diseases and how that leads to genetic variability around the globe is so cool.
      Keep making these fantastic videos.

  • @leonmessac1818
    @leonmessac1818 3 ปีที่แล้ว

    forensic files

  • @aykutrbs5088
    @aykutrbs5088 6 ปีที่แล้ว

    osteoarthritis in any near future?

    • @Medicurio
      @Medicurio  6 ปีที่แล้ว

      Will consider it!

  • @phoenix1604
    @phoenix1604 3 ปีที่แล้ว

    Five feet apart brought me here!

  • @akashappu4211
    @akashappu4211 ปีที่แล้ว

    💥💥💥😍😍😍😍😍😍

  • @AWayOfLiving84
    @AWayOfLiving84 4 หลายเดือนก่อน

    😞🕵🏻‍♂️ I need to get some more cough medicine. To break down the phlegm

  • @tylernewsome3344
    @tylernewsome3344 ปีที่แล้ว

    you need to clarify the content

  • @yme2519
    @yme2519 6 ปีที่แล้ว +2

    I don’t want to die :(((((((((((((((((( (help)

  • @xxxxsebastianxxxx
    @xxxxsebastianxxxx 7 ปีที่แล้ว

    Subscribe! Keep it up!

  • @okay.03
    @okay.03 4 ปีที่แล้ว

    i came here thx to five feet apart HAHA

  • @ARIFKhan-kz1mm
    @ARIFKhan-kz1mm 2 ปีที่แล้ว

    😫😫😫😫

  • @theonewithallthepets8503
    @theonewithallthepets8503 3 ปีที่แล้ว

    People also with Cystic Fibrosis
    👇

  • @romansrevengethethirdstrik8086
    @romansrevengethethirdstrik8086 4 ปีที่แล้ว

    This can’t be healthy.