❤ Show your support with an ICU Advantage sticker! 👉🏼 adv.icu/support 💲 10% off EACH Month @ Nurisng Mastery membership: 👉🏼 adv.icu/mastery NOTES for this lesson (and all previous lessons) are availably only to TH-cam and Patreon members. Links to join both here ⬇ ► TH-cam: adv.icu/ym | ► Patreon: adv.icu/pm
You really approve that calcium is needed for conversion of fibrinogen to fibrin? And that platelet phospholipids are not needed for prothrombinase formation?
Some tips to help remember : PT = tennis (played inside) = intrinsic pathway versus aPTT = table tennis (ping-pong, played outside) = extrinsic pathway Common pathway = 10, 5, 2, 1 = like $ currency Intrinsic = numbers 8 through 12 (except 10) Thank you so much ICU Advantage! You have greatly helped this pharmacist prep for hospital residency!
This is amazing. Having learned this about 15 years ago, I really appreciate this concise visual representation and the explanations, makes me remember a lot of things from med school :) Thanks!
Thanks so much for making this video! I was just looking into learning more about this topic the other day. I definitely have a better understanding of it now
One question, with txa it stops the process of fibrinolysis by binding with plasminogen. Why during a massive hemorrhage is the body trying to breakdown its own clots? Something I could never understand. Great videos!!
Coagulation is much faster than fibrinolysis. Normally, the clot is being lysed after the vessel is regenerated. In massive hemorrhages fibrinolysis does not play big role
You said that activated factor 11 and activated factor 12 are the ones that activate factor 7, and yet in the video illustration is showing otherwise. The video illustration is pointing at activated factor 12 and and activated factor 9. please clarify
Hello! love your videos I've been struggling with this topic for a long time. So thank you! I just have a quick (and rather dumb) question: When you were explaining the intrinsic pathway you said activated factor 12 and 11 activate factor 7 which activates the extrinsic pathway, but you drew the arrow from activated factor 9. Which one is it?😅🙈
Ahh this was my bad! It took me a minute to try and make sense of what was being asked, but once I realized my mistake it all makes sense now. I did draw it correctly, but I completely misread IX as 11 instead of 9. It is activated 9 that activates 7, along with many others. Sorry for the confusion!
Hey Larysa! First off, thanks so much for your support! Unfortunately TH-cam doesn't make it very clear. If you go to the main "ICU Advantage" TH-cam page, then at the top look for "Community" and that is where you will find the link to the notes and the current months password. Let me know if you have any issues and feel free to shoot me an email if you still do! Thank you! -Eddie
❤ Show your support with an ICU Advantage sticker! 👉🏼 adv.icu/support
💲 10% off EACH Month @ Nurisng Mastery membership: 👉🏼 adv.icu/mastery
NOTES for this lesson (and all previous lessons) are availably only to TH-cam and Patreon members. Links to join both here ⬇
► TH-cam: adv.icu/ym | ► Patreon: adv.icu/pm
❤
As a Clinical Hematology Professor, I approve! Love your videos!!!
Awesome! So cool to hear this. Thanks so much Luis and glad you enjoy them.
You really approve that calcium is needed for conversion of fibrinogen to fibrin? And that platelet phospholipids are not needed for prothrombinase formation?
I don't know why school teachers can't explain vividly and briefly like this. Thank you man. Keep up the good work 👏 🙌 👍 👌 💪
Thanks so much for that. Really glad I was able to convey the info so it made sense.
U mean medical schools?:)
@@malikasha yes med school,.all my doctor teachers know is to make med school a hell life.
@@fredoxychannel923 haha I see, dont give up
Because they don’t actually know it
You are exceptionally well spoken: you speak very clear and explain very nicely.
It is very desirable.
Some tips to help remember :
PT = tennis (played inside) = intrinsic pathway versus aPTT = table tennis (ping-pong, played outside) = extrinsic pathway
Common pathway = 10, 5, 2, 1 = like $ currency
Intrinsic = numbers 8 through 12 (except 10)
Thank you so much ICU Advantage! You have greatly helped this pharmacist prep for hospital residency!
Thanks for sharing that! I really like the currency part! And you are very welcome. Truly happy to know I'm able to help!
Forgive my ignorance, but I thought tennis is played outside and table tennis is played inside?
@@bonniehuang8696 oops! True, I meant the opposite :(
I am also teaching from time to time and really can´t get my mind wrapped around this cascade. Great Job wrapping this thing up.
Nice! Happy to help Igor!
This is excellent, from a University College London Professor of biochemistry, I also approve.
This is amazing. Having learned this about 15 years ago, I really appreciate this concise visual representation and the explanations, makes me remember a lot of things from med school :) Thanks!
You're very welcome! And glad you found it well put together and helpful!
Out of all the videos I’ve watched . This is the best one on the cascade
Thank you! Glad I was able to do a good job explaining this rather complex topic
Watched and read many things trying to understand this, and this video was what put it all together for me.
“All bleeding stops eventually”, is my favorite one liner
Haha yes and it’s so true!
Started scribing in a heme/onc clinic and this video is gonna help a ton
Glad you liked it!
Thankyou so much for this amazing video sir... Understood and grasped because of your clear and amazing teaching skills❤️❤️❤️
superb as always friend. you're the man
Thanks for teaching
Really understood everything 😊
Very helpful in developing my understanding of my factor VII deficiency hemophilia on a mechanistic level
Wonderful explanation, thanks
Really glad to hear this and you're welcome! :)
Incredibly easy to follow lesson... thank you
So great to hear this Ken!
I particularly enjoyed this presentation!
Very well simplified and understood 😊
thanks for explaining something pretty complex...
You’re welcome and glad I was able to do so in a way that made sense!
I absolutely love your lectures.
Thank you so much Rose!
Woah, clear and concise thank you!
Thanks so much for making this video! I was just looking into learning more about this topic the other day. I definitely have a better understanding of it now
Thank you very much sir for this valuable information!!
Very well explained. Thank you .
Glad it was helpful!
Great lecture
Very logical and good explanation, thanks
Thank you sir 😢
I finally understand this!!
😊 🙏 thank you so much!!
Woohoo!! Happy to help!
Your the best !
Thanks !
Pretty complicated but explained well❤
Great to hear! And yes, it is quite complicated!
Thank you so much sir.❤
This is awesome.❤ Thanks a lot
thanks it really helped!!!
Thank you
Thank you ❤❤❤❤
You're welcome 😊
Thanks !!!!!
Yw!!
Thabk you so much!
This helps very very much!
Glad it helped!
thank you so much!
You’re welcome!
Love your videos!! Thank you!
Thank you Faith! ❤️
Loved it. Thank you so much 😊
Glad to hear it!
One question, with txa it stops the process of fibrinolysis by binding with plasminogen. Why during a massive hemorrhage is the body trying to breakdown its own clots? Something I could never understand. Great videos!!
Coagulation is much faster than fibrinolysis. Normally, the clot is being lysed after the vessel is regenerated. In massive hemorrhages fibrinolysis does not play big role
You said that activated factor 11 and activated factor 12 are the ones that activate factor 7, and yet in the video illustration is showing otherwise. The video illustration is pointing at activated factor 12 and and activated factor 9. please clarify
I thought for a second I was the only one that saw that
🤩thanks
Hello!
love your videos I've been struggling with this topic for a long time. So thank you!
I just have a quick (and rather dumb) question: When you were explaining the intrinsic pathway you said activated factor 12 and 11 activate factor 7 which activates the extrinsic pathway, but you drew the arrow from activated factor 9. Which one is it?😅🙈
Ahh this was my bad! It took me a minute to try and make sense of what was being asked, but once I realized my mistake it all makes sense now. I did draw it correctly, but I completely misread IX as 11 instead of 9. It is activated 9 that activates 7, along with many others. Sorry for the confusion!
@@ICUAdvantage Thank you so much!!!
Holy craps...that's why EDDIE WATSON is the GOAT. Complex indeed
I'm sorta confused
Is it factor XII and IX that actives factor VII or factor XII and XI? Because you said the latter but indicated the former
Any one who could comment will be very much appreciated, what software or tool has been used in the video for writing ?
❤
Every time I teach this pathway, I run out of blackboard space.
Hahaha I could see that!
My head hurts 😂
Hahaha yeaaahhh...... this will do that!
Notes?
Where can I find the notes please??? ❤
Hey Larysa! First off, thanks so much for your support!
Unfortunately TH-cam doesn't make it very clear. If you go to the main "ICU Advantage" TH-cam page, then at the top look for "Community" and that is where you will find the link to the notes and the current months password.
Let me know if you have any issues and feel free to shoot me an email if you still do! Thank you! -Eddie
Flabbergasted
Thanks!!