Found your video because of the controversy involving the female Algerian boxer with Y chromosome competing with other females in the Olympics. This is very enlightening. Thank you!
@@illdoctrine9329 so u don't know if he has xx but you know he has xy are u dense ? Have you ever thought a day in your miserable life ? He is a she was assigned female at birth is a female will forever be and the sources stating she is xy aren't even known it is literally a rumor
You should consider redoing this with better sound, its likely to blow up haha Edit: after watching, maybe you wont blow up. The people who need this explained to them are too vehemently anti-science. (Also here over olympics stuff) Thanks though ❤
Do you have a email where I can email you? It seems you have an amazing understanding of sex syndromes and specific karotypes. I need help with a diagnosis of mine.
This is a really great video! theres nothing like "genetics not matching" phenotype. the problem was assuming Y equals male and X equals female when its REALLY: presence of tdf/ sry = male and lack of tdf/ sry = female, regardless of whether its located on an X or a Y. A woman is an adult human female. A human female is a human with no tdf or sry A man is an adult human male. A human male is a human with tdf or sry Female and male are sexes not genders. Woman and man are sexes specific to humans not genders. Femininity and masculinity are genders. This video further proves that sex is more binary than what is popularly believed in western culture. Any human of any sex can be any gender (which is masculinity/ femininity, not man and woman). Well done and thank you for sharing this medical knowledge with us!
No, no it does not prove it's more binary because this is still a simplified explanation. There are more genes that go into this that determine whether or not SRY is expressed. Furthermore, you can have SRY and have female development if hormone receptors do not function normally. Sex is multifactorial with genotypes and phenotypes existing on a spectrum. Your argument requires constantly moving the goalpost to whatever factor you decide is the key feature assigning someone to their binary sex.
@@Dr.BenHamiltonHello. She explained herself clearly. However, I don't understand your comment. As I understand it, there are two sexes. And then there are cases like you explained in which a person has characteristics of the two sexes. But the two sexes remain there: the one who produces the feminine gamete and the one who produced the masculine gamet. That's what sexes are. Is it not?
@@حروفالحب-ق3ز don’t you agree that there are only 2 colors, blue and red? Purple can’t be an entirely new color because it doesn’t contain anything other than blue and red!
@@Dr.BenHamilton but that's different. If you put blue paint on red paint of course it is not a new color, it is only new when out mix them and see a new color. Intersex people are indeed different than full females and full males, but they are still not a new sex, they are a different combination of sex characteristics but not a new sex. New sex would be a new shape of human that doesn't look anything like females or males. For example having a different ge-nital for reproduction that is not a va-gina or a pe-nis and doesn't look like them
@@Nocturius_Fi-Core there are cases where an XY female got pregnant and her eggs were functional! She and her partner needed intervention because it was the partner whose sperm was immobile.
You are incorrect. Yes, you can pretty much infer a person's genetics based on the fact that over 99,7% of the human populars have clear genetic binary markers of male or female. Intersex conditions do not negate binary and are simply a variation within the normal range of human diversity such as a person born with no limbs.
5:08 I would say this is incorrect since 46,XX males are biological males. As you explained they have typical internal and external male sex organs, since the SRY gene starts development of male sex organs. Nothing in their appearance is typical of female sex characteristics. The only difference to typical XY males is that 46,XX males are infertile (as are 46,XY females). In addition, 46,XX male syndrome is an extremely rare condition with 1 in 20'000 to 24'000 births being affected (for comparison: Down Syndrome occurs in 1 in 700~1'200 births). Please correct me if I'm wrong. That's just my understanding.
Just because a condition is rare does not mean we should assume everyone fits neatly into a binary box. I personally know 2 people with this condition. Sex is a combination of characteristics including chromosomes, anatomy, and hormones. XX males are chromosomally female and anatomically male, meaning they by definition have traits that do not align with a single sex. I discuss in other videos why I dislike the argument that sex is determined by a single factor. Sex is multifactorial, and treating it like there's a keystone factor is oversimplification that can get people hurt in medical practice.
@@Dr.BenHamilton Thanks for your quick reply! Really appreciate that you took the time to write back. To be honest though, I'm not sure I understand your argument here. I totally agree that biological sex is determined by more than one factor. Otherwise one could say 46,XX males are definitely "female" because of their chromosomes and disregard all the rest of it. I'm not sure what this has to do with a "binary box". I wasn't referring to a social concept of gender where some people might identify as non-binary or agender or genderfluid. I think even biological intersex conditions are incredibly rare and mostly display sex characteristics that are either more male or more female-looking. There's no third biological sex that's something other than male or female and can reproduce. At least I don't know of anything like that in humans. Is there something like that? But even if there was, exceptions don't make the rule. Most people don't even know about these extremely rare conditions and I don't think assuming that a person you meet has an atypical chromosomal condition that you can't observe with your senses serves any practical purpose in everyday life. You can always analyze life on more complex and nuanced levels and get into all the exceptions and anomalies that life has to offer but for most people that's not a viable option. I'm sure this is very relevant in medical practice though, so thanks for spreading awareness about these issues.
They may have smaller testis and smaller heights even with the sry gene. Those would be two traits that DO have to do with being "less male" or "more female" if you want to look at it that way. Being shorter height as a typical trait in xx males (not just being short for other reasons) is a symptom, and having smaller testes might not "seem" like a female trait alone, but when it is more common with this particular condition, it IS another symptom. They don't have viable sperm either. So really they are NOT exactly like an XY male in development. The fact is that XY females started out to be male and XX males started out to be female. That is just not what they ended up developing into. For the males who happen to not have the short height or small testis, they may not ever even get tested so maybe we don't really know the prevalence of this particular condition. Then there is the SRY negative percent that sometimes develops male and sometimes more female. Are they female without it? Who decides? It not only can get complicated but just when it is figured out, along comes yet another case that does not fit.
@@remiadore7921 I'm saying the black and white categories are going to be at least a little wrong for that person because they're going to be an exception for either, so the language used should make the patient comfortable instead of restrict them to a box that doesn't fit them anyway. Contrary to what many people want to believe, the world doesn't work in strict black and white.
When it comes to the Olympic sports etc I think the best solution would be athletes with XY chromosomes compete against each other and athletes with XX chromosomes compete with each other.
So you think someone who is XX and assigned male at birth with male testosterone levels and male genitalia should compete in the women's division because of their chromosomes?
@@Dr.BenHamilton I have not found males with XX syndrome with androgens as a male. They have testosterone like a woman. If you found a case I would appreciate a link to a scientific publication. Thank you
@@A.S.-ww4yu intersex people with CAIS for example don't go through puberty and they have a v-agina. Just cuz they have xy chromosomes they shouldn't fight with women? It is just like letting a 8 year old boy box with his 9 year old sister
The names for these people is determined by male egoism and their sexism unless the person themselves identify that way. Science is suppose to guide us to a better understanding of ourselves and by classifying people as male or female without their consent is complete sexism and has no place in science. This video is sexist.
I'm not classifying people as male or female without their consent. If you watch the video instead of just reading the title, my point is that sex is bimodal and not everyone fits into boxes. Modern day guidelines are to wait for the child to self identify. My entire channel advocates for moving away from the outdated classifications.
Found your video because of the controversy involving the female Algerian boxer with Y chromosome competing with other females in the Olympics. This is very enlightening. Thank you!
We still don't know if she actually has xy chromosomes or not
@@marwabed5109
We still don’t know whether he has XX chromosomes. We *do* know he has XY chromosomes.
@@illdoctrine9329 so u don't know if he has xx but you know he has xy are u dense ? Have you ever thought a day in your miserable life ? He is a she was assigned female at birth is a female will forever be and the sources stating she is xy aren't even known it is literally a rumor
@@illdoctrine9329where did you find this? can you link a specific article, not taking a side, just asking where you found this information
@@marwabed5109 because IBA confirmed it. He has xy chromosome
You’re going to be famous soon! 🎉❤ Happy Olympics!
I’m glad my video from 3 years ago is still applicable 😊
Thank you for posting this. Education is what is needed.
Thank you for making this complicated subject easier to follow x
You should consider redoing this with better sound, its likely to blow up haha
Edit: after watching, maybe you wont blow up. The people who need this explained to them are too vehemently anti-science. (Also here over olympics stuff)
Thanks though ❤
Your explanationing is awesome!!
Writing tho 😉 no no, totally on point! 👌
what about someone with 45,X/46,XY, is that possible and is that common？What will happen to their lives then？
Do you have a email where I can email you? It seems you have an amazing understanding of sex syndromes and specific karotypes. I need help with a diagnosis of mine.
Twitter is the easiest way to reach me. Do you have a physician that you see about this diagnosis?
@@Dr.BenHamilton diagnoses only has ever been recorded 18 times. They are unsure what to do with me. I will try to reach out on Twitter.
This is a really great video!
theres nothing like "genetics not matching" phenotype. the problem was assuming Y equals male and X equals female when its REALLY: presence of tdf/ sry = male and lack of tdf/ sry = female, regardless of whether its located on an X or a Y.
A woman is an adult human female. A human female is a human with no tdf or sry
A man is an adult human male. A human male is a human with tdf or sry
Female and male are sexes not genders. Woman and man are sexes specific to humans not genders. Femininity and masculinity are genders. This video further proves that sex is more binary than what is popularly believed in western culture. Any human of any sex can be any gender (which is masculinity/ femininity, not man and woman). Well done and thank you for sharing this medical knowledge with us!
No, no it does not prove it's more binary because this is still a simplified explanation. There are more genes that go into this that determine whether or not SRY is expressed. Furthermore, you can have SRY and have female development if hormone receptors do not function normally. Sex is multifactorial with genotypes and phenotypes existing on a spectrum. Your argument requires constantly moving the goalpost to whatever factor you decide is the key feature assigning someone to their binary sex.
@@Dr.BenHamiltonHello. She explained herself clearly. However, I don't understand your comment.
As I understand it, there are two sexes. And then there are cases like you explained in which a person has characteristics of the two sexes.
But the two sexes remain there: the one who produces the feminine gamete and the one who produced the masculine gamet.
That's what sexes are. Is it not?
@@Dr.BenHamilton but it is true that only 2 sexes exist, which is male and female. Intersex means in between, not a completely new sex.
@@حروفالحب-ق3ز don’t you agree that there are only 2 colors, blue and red? Purple can’t be an entirely new color because it doesn’t contain anything other than blue and red!
@@Dr.BenHamilton but that's different. If you put blue paint on red paint of course it is not a new color, it is only new when out mix them and see a new color. Intersex people are indeed different than full females and full males, but they are still not a new sex, they are a different combination of sex characteristics but not a new sex.
New sex would be a new shape of human that doesn't look anything like females or males. For example having a different ge-nital for reproduction that is not a va-gina or a pe-nis and doesn't look like them
Hi there! I wonder if those people are fertile or sterile in that case ?
Some of them have been able to get pregnant!
@@Dr.BenHamilton With egg implantation? I read they don't produce their own sperms and eggs, am I correct?
@@Nocturius_Fi-Core there are cases where an XY female got pregnant and her eggs were functional! She and her partner needed intervention because it was the partner whose sperm was immobile.
@@Dr.BenHamilton Thats amazing!
Sterile
My daughter was born with Swyers syndrome
Is she intersex?
Wow how did you discover so early. I thought they only discover after marriage
We talked or you talked?
You are incorrect. Yes, you can pretty much infer a person's genetics based on the fact that over 99,7% of the human populars have clear genetic binary markers of male or female.
Intersex conditions do not negate binary and are simply a variation within the normal range of human diversity such as a person born with no limbs.
Sound sucks big time
5:08 I would say this is incorrect since 46,XX males are biological males. As you explained they have typical internal and external male sex organs, since the SRY gene starts development of male sex organs. Nothing in their appearance is typical of female sex characteristics. The only difference to typical XY males is that 46,XX males are infertile (as are 46,XY females). In addition, 46,XX male syndrome is an extremely rare condition with 1 in 20'000 to 24'000 births being affected (for comparison: Down Syndrome occurs in 1 in 700~1'200 births). Please correct me if I'm wrong. That's just my understanding.
Just because a condition is rare does not mean we should assume everyone fits neatly into a binary box. I personally know 2 people with this condition. Sex is a combination of characteristics including chromosomes, anatomy, and hormones. XX males are chromosomally female and anatomically male, meaning they by definition have traits that do not align with a single sex. I discuss in other videos why I dislike the argument that sex is determined by a single factor. Sex is multifactorial, and treating it like there's a keystone factor is oversimplification that can get people hurt in medical practice.
@@Dr.BenHamilton Thanks for your quick reply! Really appreciate that you took the time to write back.
To be honest though, I'm not sure I understand your argument here. I totally agree that biological sex is determined by more than one factor. Otherwise one could say 46,XX males are definitely "female" because of their chromosomes and disregard all the rest of it. I'm not sure what this has to do with a "binary box". I wasn't referring to a social concept of gender where some people might identify as non-binary or agender or genderfluid. I think even biological intersex conditions are incredibly rare and mostly display sex characteristics that are either more male or more female-looking. There's no third biological sex that's something other than male or female and can reproduce. At least I don't know of anything like that in humans. Is there something like that? But even if there was, exceptions don't make the rule. Most people don't even know about these extremely rare conditions and I don't think assuming that a person you meet has an atypical chromosomal condition that you can't observe with your senses serves any practical purpose in everyday life. You can always analyze life on more complex and nuanced levels and get into all the exceptions and anomalies that life has to offer but for most people that's not a viable option. I'm sure this is very relevant in medical practice though, so thanks for spreading awareness about these issues.
They may have smaller testis and smaller heights even with the sry gene. Those would be two traits that DO have to do with being "less male" or "more female" if you want to look at it that way. Being shorter height as a typical trait in xx males (not just being short for other reasons) is a symptom, and having smaller testes might not "seem" like a female trait alone, but when it is more common with this particular condition, it IS another symptom. They don't have viable sperm either. So really they are NOT exactly like an XY male in development. The fact is that XY females started out to be male and XX males started out to be female. That is just not what they ended up developing into. For the males who happen to not have the short height or small testis, they may not ever even get tested so maybe we don't really know the prevalence of this particular condition. Then there is the SRY negative percent that sometimes develops male and sometimes more female. Are they female without it? Who decides? It not only can get complicated but just when it is figured out, along comes yet another case that does not fit.
@@jmd42jmd46 Yes, there are always exceptions to the rule that are not well understood and lack research.
De La Chapelle is around 1:1000 male live births if I'm not mistaken. So way more common than 24,000
I'm too tired to be clever so this comment has to do.
So are XS males still males and XY females are still females
I think they could be either depending on how the person feels about it.
@@Dr.BenHamilton so basically your saying they could be biologically XX FEMALE INSTEAD OF XX MALE depending on how they feel about it
@@remiadore7921 I'm saying the black and white categories are going to be at least a little wrong for that person because they're going to be an exception for either, so the language used should make the patient comfortable instead of restrict them to a box that doesn't fit them anyway. Contrary to what many people want to believe, the world doesn't work in strict black and white.
Biologically speaking these people are both biologically male AND biologically female, since chromosomes and anatomy both constitute biological sex.
@@Dr.BenHamilton so out in the world they can identify whichever one they please I’m SOCIAL SITUATIONS
😍😍😍
When it comes to the Olympic sports etc I think the best solution would be athletes with XY chromosomes compete against each other and athletes with XX chromosomes compete with each other.
So you think someone who is XX and assigned male at birth with male testosterone levels and male genitalia should compete in the women's division because of their chromosomes?
@@Dr.BenHamilton I have not found males with XX syndrome with androgens as a male. They have testosterone like a woman. If you found a case I would appreciate a link to a scientific publication. Thank you
@@A.S.-ww4yu intersex people with CAIS for example don't go through puberty and they have a v-agina. Just cuz they have xy chromosomes they shouldn't fight with women? It is just like letting a 8 year old boy box with his 9 year old sister
The names for these people is determined by male egoism and their sexism unless the person themselves identify that way. Science is suppose to guide us to a better understanding of ourselves and by classifying people as male or female without their consent is complete sexism and has no place in science. This video is sexist.
I'm not classifying people as male or female without their consent. If you watch the video instead of just reading the title, my point is that sex is bimodal and not everyone fits into boxes. Modern day guidelines are to wait for the child to self identify. My entire channel advocates for moving away from the outdated classifications.
Y'all lie a awful lot not to be a owl
I guess my chromosomes were lying when they revealed to be XX as a male
@@orenz.272 Then you're a female
@@orenz.272xx chromosomes means you are a biological female.