Cyclic Acetal Protecting Group Reaction and Mechanism

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  • เผยแพร่เมื่อ 11 ก.ย. 2024
  • leah4sci.com/ac... Presents: Cyclic Acetal Protecting Group Reaction and Mechanism in Organic Chemistry
    📺Watch Next: TMS Alcohol Protecting Group • TMS Alcohol Protecting...
    Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: leah4sci.com/or...
    In this video:
    [0:22] Acetal Protecting Groups Review
    [1:54] Using the Gas Mask Trick
    [2:52] Step by Step Analysis of Sample Problem
    [6:27] Re-Draw Molecule
    [9:14] Acid Catalyst Regeneration
    This video shows you the detailed mechanism for forming cyclic acetal protecting groups! You'll also see tips about redrawing, and a time saving shortcut to use during practice and your upcoming exam!
    Catch the entire Acetal Video Series along with the Acetal Practice Quiz and Cheat Sheet on my website at leah4sci.com/ac...
    For more in-depth review on Acetals including practice problems and explanations, come join my online membership site the organic chemistry study hall: leah4sci.com/join
    For private online tutoring visit my website: leah4sci.com/or...
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ความคิดเห็น • 74

  • @arsenal78910
    @arsenal78910 6 ปีที่แล้ว +20

    I'm learning this right now in Orgo II. Perfect upload timing, thank you!!

    • @Leah4sci
      @Leah4sci  6 ปีที่แล้ว +1

      That's awesome! glad to help

  • @Silicon_Insider
    @Silicon_Insider 5 ปีที่แล้ว +4

    You are simply the best, LEAH. You made my organic chemistry 1 so easier and you still making the 2 as well. BRAVO! Keep up with the good work

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      Thanks Bernard! Always glad to help. :)

  • @calebanderson5309
    @calebanderson5309 5 ปีที่แล้ว +5

    you might be my favorite person in the world. thank you so much for your amazing videos

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      Awww! thanks! and you are very much welcome! :)

  • @derrickalusa4599
    @derrickalusa4599 3 ปีที่แล้ว +2

    Finally..some good teaching when I needed it... thanks

    • @Leah4sci
      @Leah4sci  3 ปีที่แล้ว

      Glad it was helpful and you're welcome!

  • @mohitrawat655
    @mohitrawat655 4 ปีที่แล้ว +4

    Hey Leah, can you please make a couple of more videos in this series
    1. regarding the protection of the ketone group in a compound where aldehyde and ketone both are present.
    2. some complex practice questions.
    That'll be a lot of help. Thanks

    • @Leah4sci
      @Leah4sci  10 หลายเดือนก่อน

      Thank you for the suggestions

  • @Truth_Çkr
    @Truth_Çkr 4 ปีที่แล้ว

    You just saved my homework grade. One of the best online science teachers with out a doubt

    • @Leah4sci
      @Leah4sci  4 ปีที่แล้ว

      Thanks! Glad I could help!

  • @wilsoncombs9349
    @wilsoncombs9349 ปีที่แล้ว

    Only video of this mech I could find thx

    • @Leah4sci
      @Leah4sci  ปีที่แล้ว

      you're so welcome

  • @ankitsehgal8026
    @ankitsehgal8026 5 ปีที่แล้ว +2

    Thnku so much..
    Respect for u from india

    • @Leah4sci
      @Leah4sci  9 หลายเดือนก่อน

      You're very welcome

  • @pexaminer
    @pexaminer 2 ปีที่แล้ว

    One word - Excellent.

    • @Leah4sci
      @Leah4sci  2 ปีที่แล้ว

      Thanks so much!

  • @afrahsultana2581
    @afrahsultana2581 10 หลายเดือนก่อน

    Thank you , ure explanation is very helpful mam😁😁

    • @Leah4sci
      @Leah4sci  10 หลายเดือนก่อน

      You're very welcome!

  • @anasbadran2618
    @anasbadran2618 4 ปีที่แล้ว +1

    Very nice and helpful ,,,thanks a lot ❤❤❤❤

    • @Leah4sci
      @Leah4sci  4 ปีที่แล้ว +1

      You're very welcome!

  • @chidijohnsonagwu3621
    @chidijohnsonagwu3621 4 ปีที่แล้ว

    This was so helpful, thank you!

    • @Leah4sci
      @Leah4sci  4 ปีที่แล้ว

      You're so welcome!

  • @Shubham.Kumar.Mishra
    @Shubham.Kumar.Mishra 6 ปีที่แล้ว +1

    Best explanation...thanks..

    • @Leah4sci
      @Leah4sci  6 ปีที่แล้ว

      You're very welcome

  • @akshansh3412
    @akshansh3412 6 ปีที่แล้ว +2

    Thank you, Mam!

    • @Leah4sci
      @Leah4sci  6 ปีที่แล้ว

      You're very welcome

  • @Divinepoox
    @Divinepoox 5 ปีที่แล้ว +1

    Am I the only one who sees a smiley face around the cyclic acetal protecting group @ 2:08, or am I just turning crazy?

    • @deepyaa3392
      @deepyaa3392 2 ปีที่แล้ว +1

      You aren't the only one

    • @Leah4sci
      @Leah4sci  9 หลายเดือนก่อน

      Orgo makes you see things! Try looking at the budweiser logo without seeing a chair conformation 🤣🤣

  • @moussachehab8754
    @moussachehab8754 5 ปีที่แล้ว +2

    Great video thanks! Just one question, my professor had the other alcohol on the diol attacking the electrophilic carbon center kicking off the water, whereas you had the oxygen resonate to kick off the water. Does it matter which way the water leaves? Again, Thanks!

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      I'm sorry, but I don't offer tutoring through TH-cam comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join

  • @mustakim2144
    @mustakim2144 6 ปีที่แล้ว +1

    Thank you!

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      You're welcome!

  • @abhilashbabu6612
    @abhilashbabu6612 6 ปีที่แล้ว

    Finally I got the answer for my MCAT question!

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      Glad the video helped!

  • @LMAO-fs1bt
    @LMAO-fs1bt 3 หลายเดือนก่อน

    Thanks

    • @Leah4sci
      @Leah4sci  2 หลายเดือนก่อน

      You're very welcome

  • @kennedymungai6022
    @kennedymungai6022 3 ปีที่แล้ว

    GREAT VIDEO my question is if the diol used has the hydroxyl groups in the middle like butan-2,3-diol does the mechanism proceed the same as it did with the 1,2-ethandiol

    • @Leah4sci
      @Leah4sci  3 ปีที่แล้ว

      Glad you like it! Yes, the mechanism would proceed in the exact same way. In your particular example, the only difference would be a couple of extra methyl groups present on your cyclic acetal. All electron-pushing arrows would follow the same pattern.

  • @varunij5824
    @varunij5824 3 ปีที่แล้ว

    Thank u so much!!

    • @Leah4sci
      @Leah4sci  3 ปีที่แล้ว

      You're welcome!

  • @JP_vlog511
    @JP_vlog511 5 ปีที่แล้ว

    Very good

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      Glad you like it!

  • @maybebaby8243
    @maybebaby8243 6 ปีที่แล้ว

    Thanks a lot, your videos are helping a looooot! I just have one question.. If we have a normal alcohol with only one OH group, the product is going to be with 2 O atoms that are not bonded with C atoms chain, and if we have an alcohol such as 1,4- diol with 2 OH groups, the 2 O atoms are going to be bonded with an C atoms chain (''monster''); am I right? TIA!

    • @aggelosharalabidis6915
      @aggelosharalabidis6915 6 ปีที่แล้ว

      you are right

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      I'm sorry, but I don't offer tutoring through TH-cam comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join

    • @Czar_Char
      @Czar_Char 2 ปีที่แล้ว

      @@Leah4sci kmfd!!!!!!

  • @Tia-oy3ew
    @Tia-oy3ew 3 ปีที่แล้ว

    I LOVE YOU THANKYOUUUU

    • @Leah4sci
      @Leah4sci  3 ปีที่แล้ว

      You're welcome!

  • @sugabear9511
    @sugabear9511 5 ปีที่แล้ว

    Thank u sooooo much

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว +1

      You're welcome!

    • @sugabear9511
      @sugabear9511 5 ปีที่แล้ว

      Leah4sci omg!!!!! I can't believe u replied i love u so much u are my idol ❤❤

  • @shadnazbordbar6541
    @shadnazbordbar6541 2 ปีที่แล้ว

    Hi thank you for your help but in the formation of acetal from hemiacetal are you sure H2o+ won't leave on its own? because my professor didn't make the pi bond from lone pair on O and simply said this is an SN1 reaction and H2o+ is a good leaving group so it would leave on its own followed by a NA by the second alcohol.

    • @Leah4sci
      @Leah4sci  2 ปีที่แล้ว

      I'm confident in my mechanism, but you should always know what your teacher wants you to draw. The water is a good leaving group, but rather than form a carbocation, I believe the preference would be to allow carbon to follow the octet rule and give the positive charge to oxygen.

    • @Czar_Char
      @Czar_Char 2 ปีที่แล้ว

      @@Leah4sci herh mbaaa

  • @mukesh2400
    @mukesh2400 6 ปีที่แล้ว +1

    Great

  • @MuhammadJaved-sm4yh
    @MuhammadJaved-sm4yh 6 ปีที่แล้ว

    Very nice mam

    • @Leah4sci
      @Leah4sci  6 ปีที่แล้ว +1

      Thanks Muhammad

  • @korangalalita1229
    @korangalalita1229 6 ปีที่แล้ว

    Thanks mam

    • @Leah4sci
      @Leah4sci  5 ปีที่แล้ว

      You're welcome :)

  • @alexandera3482
    @alexandera3482 4 ปีที่แล้ว

    HOW DO U REMOVE THE ACETAL

    • @Leah4sci
      @Leah4sci  3 ปีที่แล้ว

      The acetal protecting group can be removed by the addition of acid in water. It would be an acid-catalyzed hydrolysis of the acetal.

  • @benjaminskinner4634
    @benjaminskinner4634 4 ปีที่แล้ว

    Thanks bae

    • @Leah4sci
      @Leah4sci  4 ปีที่แล้ว

      You're welcome!

  • @jamesankers9746
    @jamesankers9746 5 ปีที่แล้ว +1

    Methanamine r u mad it’s not that it is methylamine (a previous video)

    • @anjanibhardwaj7761
      @anjanibhardwaj7761 3 ปีที่แล้ว

      Hey it is methanamine as well ..... she's not mad

    • @Leah4sci
      @Leah4sci  9 หลายเดือนก่อน

      I could be, who knows?

  • @TonyZeitgeist
    @TonyZeitgeist 2 ปีที่แล้ว

    Ketones form ketals, not acetals.

    • @Leah4sci
      @Leah4sci  2 ปีที่แล้ว

      According to current IUPAC rules, ketals are a subset of acetals. The term "acetal" encompasses both aldehyde-derived and ketone-derived structures.

  • @akankshatyagi8959
    @akankshatyagi8959 4 ปีที่แล้ว

    Can you provide in hindi please I m from India 🇮🇳

    • @Leah4sci
      @Leah4sci  4 ปีที่แล้ว +1

      Thanks for the suggestion, but this is something I do when I have extra time, so providing in Hindi isn't something I can do right now.