What do 5' and 3' mean on DNA and RNA? (Intro Biology)
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- เผยแพร่เมื่อ 16 มิ.ย. 2024
- Confused about the 5' and 3' (five prime and three prime) ends of DNA and RNA? You're not alone - I got you!
The 5' and 3' ends of nucleic acids give a sequence directionality. The cell needs to know which direction to read all of those A's and G's and C's and T/U's - it means a different thing if you read it in the opposite direction! For some processes, the cell reads 5'-3', (ex: codons during translation) and for other processes, the sequence is read in the 3'-5' direction (ex: the template strand during DNA replication).
00:00 Intro
00:22 DNA and RNA sequences and directionality
00:50 A non-sciencey example of directionality
01:06 Nucleotide structure (where the 5' and 3' comes from)
02:15 Identifying the 5' and 3' end of a nucleotide (or sequence)
02:53 Things to watch out for on an exam!
04:26 Thanks!
[IB Biology 1.2.11]
This deserves more views. Fantastic explanation!
Thanks for the kind comment - I'm so pleased that you found it helpful!
amazing, simple explanation! Many teachers never actually explain what and why the 5’ and 3’, just tell students to memorize is as a fact. Understanding is key to memorizing, so thank you for this :)
I LOVE this feedback - you're so right about the importance of understanding. Best of luck with your studies!
thank you very much this helped me, our teacher gave us some greyscale textbook screenshot and expected us to understand...
Fantastic! I feel like adding a little color always helps :)
Underrated Prof!
Umm...underrated comment - thanks for the love!
This was life saving
SO glad it was helpful - best of luck with your studies!
And that was my assignment done. Thank you
Fantastic - so glad it helped!
Brilliant!! This was so helpful.
I love to hear that - best of luck with your studies! ❤️
Thank you soooo muchhh for this explanation, it was so confusing until i found this video, hats off!
That's so awesome - I'm glad it all makes sense now! Best of luck with your studies!
Nice explanation
Thanks for the feedback - best of luck with your studies!
Very helpful and easy to understand, thank you
Fantastic! So glad it helped :)
Yes,I have always been confused about 5 prime and 3 primer ends.But now I've nicely understood
Thanks a lot for ur help ❤️
I wanted to ask Do the two helical strands wound on same axis or opposite axis
It might help to see a labeled image of the double-helix: www2.nau.edu/lrm22/lessons/dna_notes/dna_notes.html
You can see how the two strands twist in the same way around the same axis to make the double helix shape, but with opposite 5'-3' directionality.
@@yourOTHERbiologyprof thanks alotttttt❤️❤️❤️
@@FatimaFatima-ls5kg You're so welcome - best of luck with your studies!
Beautiful explanation, buttt i am a little confuse with the translation process and the direction followed by the ribosome complex to synthetize the polipeptide chain through the mRNA U.U
The mRNA codons are read in the 5' -> 3' direction.
You might remember that eukaryotic mRNAs have a 5' cap - that's where the ribosome starts, and it scans toward the 3' end of mRNA looking for that first AUG to start building the polypeptide chain...an amino acid gets added for each additional codon until a stop codon is reached.
So, like:
5'---codons---3'
-> -> -> -> ->
or
3'---snodoc---5'
More biology AND info on tutoring at: www.yourotherbioprof.com ❤