DeFronzo on a novel renal-hepatic axis in endogenous glucose production, arguments for and agains...

Welcome to the June 2024 episode of DiabetesBio-the American Diabetes Association’s podcast for its flagship research publication, Diabetes (diabetesjournals.org/diabetes) . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2024 issue of Diabetes.
2:27: Darleen and Kirk are joined by Dr. Ralph A. DeFronzo (directory.uthscsa.edu/academi...) , senior author of the article “Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2D and NGT Subjects.” This article is freely accessible at doi.org/10.2337/db23-0457.
20:26: In this month’s Sweet Talk segment, Kevin and Kirk highlight this month’s Point-Counterpoint feature on whether a new model is needed on the regulation of β-cell KATP channels in glucose metabolism. First, they talk to Drs. Matthew J. Merrins (bmolchem.wisc.edu/staff/merri...) and Richard G. Kibbey (medicine.yale.edu/profile/ric...) , authors of the Counterpoint, titled “Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model!” This article is freely accessible at doi.org/10.2337/dbi23-0032.
35:00: Kevin next is joined by Drs. Guy A. Rutter (profiles.imperial.ac.uk/g.rutter) and Ian R. Sweet (uwmdi.org/faculty/ian-sweet-phd/) , authors of the Point article, titled “Glucose Regulation of β-Cell KATP Channels: Is a New Model Needed?” This article is freely accessible at doi.org/10.2337/dbi23-0031.
To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes (diabetesjournals.org/diabetes) . Thank you for listening, and don’t forget to smash that “follow” button!