The food noise comment is real. When I first got on zepbound I remember being angry that I didn’t enjoy food anymore. No meal made me “happy”. And after a few months I started to realize “my happiness isn’t tied to food”. That tiny shift in how my mind thinks about food was a real game changer. The difference between “I don’t feel happy eating food” and “I don’t need to eat to be happy” is STAGGERING.
There are chemicals in food that form compounds in our stomachs. Sugar and gluten form a compound similar to morphine. It is a pain killer. You did not take a weight loss pill or shot. You turned off the addiction part. Those compounds. Stop taking it and you are still addicted. Healing takes time and work. I thank you for your work and may you continue to live and be happy. With or without food. Your body is yours and no one should be able to say it needs to be different. It is just soul clothes and nobody looks the same but all of our souls do. Your clothes are fine.
It's just self calibration... When I've been on Keto for even a WEEK, a candy bar tastes DISGUSTINGLY sweet. To the point I would need to force myself to eat it. But ANY ripe fruit would smash that candy bar easily... Only once you start getting back into junk/sugar do those tastes begin to shift again...
@@mcbrite It really isn't. You talk like I haven't lost more than 100lbs via willpower alone, or 60lbs via keto, or multiple other diet trends. The difference between zepbound and the normal "diet and exercise" advice, in my personal experience, is that NO food produces a serotonin/dopamine response on zepbound. When I was keto, a steak was still a "happy" meal, as was a rotisserie chicken. When I was calorie counting, everything was still a "happy" meal. On zepbound, my favorite foods, like curry, or steak, or etouffee, or sushi are all just sustenance. I have no desire to finish the meal, and often don't. I get a few bites in and often decide to just put the fork down because I don't want it. I'll go to a gas station, and just get a drink, and skip the chips and candy, because they don't seem appealing. Heck, even alcohol is significantly less appealing, which is just another benefit to my health. No matter what diet I was on previously, there was always room for a few ounces of whiskey a week. I don't even want that anymore. What I'm trying to say is, my whole life, food and drink have been my PRIMARY source of dopamine and serotonin, and now, for the first time in my adult life, they're not. They don't give me that feeling, and it's forced me to change how I live, not only with regards to food, but also my personal life. I had to find new sources of happiness outside of food, and I'm a better PERSON for it. Everyone's different, and your results with controlling your diet very well could have produced different results than my own, but to discount it as "it's just self-calibration" doesn't just attempt to discount my own personal anecdote, it also seeks to discount the actual science done studying how the drug functions and it's impacts on those taking it.
I had already lost over 100 pounds before Ozempic so my mind shift had already happened, but the food noise thing is real. I still had tons of food noise and Ozempic had helped a ton.
First of all, all weight loss and a lot of anti anxiety/ssri’s meds have serious life altering/destroying effects on you and their effectiveness rarely makes up for your suffering‼️ Be very careful. These meds have a short term use benefit, ONLY short term‼️
Both of my parents are overweight and diabetic. They were both put on Ozempic. It seemed to work well for my dad, but my mom never got past the initial low dose phase. She got severe gastrointestinal pain and vomiting. So I can see how the drug is not for everyone
@@Intoxicatious there’s not a single drug on earth that is for everyone. Even ibuprofen. Biology will teach you why. Nature wants to increase diversity and change.
I initially took ozempic for weight loss however only lost 25lbs in 11 months. However after 20+ yrs as a diabetic I officially have it controlled. I'm no longer injecting insulin 4x a day and no more Metformin! I've had no crazy side affects and blessed to only have to take a once a week injection!
I hear you sister. With the body of a college athlete, keto diet and exercise, I could not control my DM2 until Ozempic arrived. Of course, I am using prescription compounded semaglutide as insurance won't approve Ozempic because I do not have "complex" or "multiple comorbidities" - I eat too well and exercise appropriately.
25 pounds in 11 months is nothing to scoff at! That’s still incredible and a large amount of weight. Give yourself some credit cuz you deserve it, and nice job on getting your diabetes under control!
I did a wegovy course and lost 54lbs in 6 months. Have been off it now for 6 months and am still down 48lbs with almost all the regain being the first two months off it. I am no longer fat enough to get the insurance to cover it again lol.
So what you're saying is that the insurance system is structured to *guarantee* the "yo-yo effect." The drugs are designed to be used indefinitely, but insurance is designed to resist that usage profile.
Yes damaging your digestive system to freeze up… is perfectly fine? What do we do about all the impulsive fat slobs? Give them receptor agonists…. You know what receptor agonists do? Agonist and antagonists… they block or activate target receptors like anti-depressives etc. There is such thing as receptor dysregulation due to these types of drugs. This happens because its the mechanism behind addiction. Your body has a feedback that will reduce or increase receptor volume depending on how much external or internal agonists or antagonists the receptors engage with. So you might be losing weight but your receptor volumes/balance are 1000% getting damaged. Just like meth heads etc. thats all of you ozempic zombies.
I have Lupus and experience something called wasting disease, it causes dramatic changes in weight and the sicker I get the more compliments I get… it’s almost ridiculous at this point. “Girl you look great!” I’m like thanks it’s an illness 😂😂
Sorry to hear that! 😢 I have a milder autoimmune disease so I'm familiar with lupus. Neither it nor wasting disease sound like fun at all (to put it mildly). I hope we get some monoclonal antibody, other immunotherapy, or next gen probiotics treatments soon that effectively cure diseases like lupus, MS, RA, Sjogren's, Hashimoto's, etc. There's already a lot of research into the microbiome suggesting that FMT can potentially put some autoimmune diseases into remission, but FMT has the psychologically gross angle to it (even if purified) plus it doesnt scale up as well as other treatments might. Anyway, if you regularly see a rheumatologist, it's worth asking to see if they are monitoring that space, because out of genetics, environment/diet, and microbiome factors, only one so far has been very addressable, as conventional probiotics dont do much and gene therapy is still expensive and experimental for many conditions, beyond some promise of mRNA and other breakthroughs.
So sorry. This is exactly why I think no one should ever comment on someone else's weight. There may be health reasons, medication changes like chemotherapy, and mental health issues causing weight gain or weight loss.
@@CinnastixChickI think giving someone a compliment is totally fine even if you don’t know their backstory. Obviously any rude and disrespectful opinions should always be kept to oneself though.
I lost 30 pounds in 3 weeks with mono and people were like, "You look great" and I was like, "Thanks, I was nearly hospitalized because I couldn't swallow."
I have been on tirzepatide for about a year now for type 2, but I went from 215 to 155 in about a year. It had some side effects yes, but I also have great labs now, and I am no longer diabetic. Doesn't work for everyone, but it has changed my life and the biggest thing people are not talking about is how much I have saved on food cost over the last year.
Let them. It won't stop people from realizing the cost of living is cheaper than snacking. This goes beyond some vanity reason to look better. This genuinely curbs potential for heart disease and heart attack in many patients and that benefit alone cannot be emphasized enough.@@Hypnotoad582
@@Worldaffairslover Great question, my guess is I would slowly pack it all back on, I gained all my weight a few pounds a year over years, I snacked at night and drank lots of beer, the meds have made me snack less at night and drink much much less beer. Old habits die hard, I am on a lower does now. Since I have the diabetic diagnosis, as far as I know I will be on it forever. I also take metformin daily.
What I loved the most on ozempic is not even the weight loss is this sense of FREEDOM from food addiction. That I can start my day not feeling like food has an importance. That I can focus my energy on something else than food and the pleasure it brings. This satiety feeling is priceless, the feeling to be full is just really confortable. It made an end to this eternal emptiness and desire to eat snack that I had before. I didn't had to worry about calories , macros.... no nothing, my body was in a state where it can regulated himself without me having to "self control " my hunger, to work on felling satiety ( I was never able to feel it). For the first time I felt like everyone else: Eating a meal , feeling satiety up to the next meal. Then losing weight become easy without those craving !
You take something very important from your body too. It is called hunger. As shown, loss of the feeling of hunger dampens your general activity over longer time spans. Not a smart idea!
@@dr.paulwilliam7447 Hunger was there , manifesting gently, slowly building,. The medicine is actually not cutting hunger at all but it works with the satiety hormones, it's not the same thing. Feeling full after a meal is what was different from before.
Marketing ploy...........in the end this still became a commercial for Novo Nordisk, and an excuse to pacify and enable the lazies and lack of self control in scamerica. 💊💊💊💊💊💊 over vegetables and exercise
The so called "food noise" is the body responding to a lack of nutritious food. It is screaming for nutrients and fiber. We interpret this as food cravings but the cravings are never satisfied because the food lacks the nutrients the body needs. That is why you see people eat a 3 course meal and still feel hungry 30 minutes later. A lot of folks sabotage their diets with high glycemic foods.
@@megeek727 idk if it's fair or realistic to sum it up so simplistically. As someone who has, at times, had an extremely nutritious diet with very limited carbs and high intake of healthy proteins and fats and fiber, and at other times in my life, had a much shittier diet, the food noise has just always been there. As a constant. We're talking like a voice in my head going *snack snack snack snack get a snack go get a snack when was the last time I ate oh man I really want a sweet and salty snack I need it I need it* All the time, regardless of how "good" I was being at a given time about my overall diet. And that's why all my good, healthy dieting eras never lasted permanently, because of the overwhelming food noise. But in the last 4 months with Zepbound, it's just.... so much quieter. I wouldn't say my internal monologue about snacks is COMPLETELY gone, but I find that I'm able to redirect my attention pretty easily now, in a way I just couldn't manage to before. It's now more like *hmm I haven't had a snack in a while, maybe I should get a snack? Eh, I don't think I need it. I'll just play with my dog.* So I'm pretty inclined to disagree with your suggestion that the food noise phenomenon from GLP-1 drugs could just be replaced with better nutrients and fiber. Especially when obese people have been trying the "just eat better" approach for decades with a 95% overall failure record. In fact, the whole conclusion of this video supports the idea that we should all be avoiding the impulse to overly simplify anything when it comes to obesity, nutrition, and fitness.
"Food noise" might be apt and real, but it needs as much skepticism as the "chemical imbalance in the brain" marketing that was used for some medications in the past that had little or no supporting evidence. It might be a useful phrase to describe an addiction, but beware the stealth marketing angle that uses it as a talking point or amplifies that PR messaging. Anything that potentially works that broadly should be as much cause for concern and monitoring, not just seen as a panacea for addiction.
I have a PhD in Genetics and TH-cam is not the place to teach genetics to people. BUT, I just want to take 1 minute to explain a basic concept. Next time you are in public, look at people around you. We all look different, you agree? What you have to understand is that it doesn't stop with the outside, it is exactly the same with our cells. We are all different. Even children from the same parents are not clones of each other (even twins). So how can you believe that any given drug (or technique or whatever) is going to work the same for you body and for the person next to you?
@@TimelyAbyss Or, when we have Covid-19 (and I apologize for the BS that was said in the news), it is why you have people who are sensitive to the virus (and will die because we don't have the technology, yet, to save them) and others that are resistants... It is the same pattern with all bug, just the percentage of sensitives/resistants change (of course there are some people in between that we could save - and, also, it is a dynamic equilibrium - etc.).
@@megeek727 Any drug work differently for any single individual... Worse, the recommended dose for drugs is not always adapated to all individual and can sometimes present severe risks (yes, paracetamol, I am talking about you).
6:20 it might be a big win for big pharma but it's an L for the junk food industry. I save so much money on food now and I only have a $50 co-pay. Since I eat less, my body is constantly demanding healthier foods to keep me going. The only time I'm eating junk food is when theres literally no other option.
(I’m not being critical and see the benefits of the drug. I’m very pragmatic.) Generally, if people get committed to exercising and getting healthier, it trains your taste buds over time. And, a mental mindset.
@@HKim0072 I argue it doesn’t train your taste buds, rather with increased good food intake the body adjusts to higher efficiency energy sources which causes the dopamine response to processed sugars to decrease which is perceived internally as the body preferring nutrient dense food sources (or in my case demanding high protein & fat, aka ketones, causing me to feel sick when blood sugar spikes instead of ketones)… Not on ozempic but made the switch naturally.
The U.S. arm of pharmaceutical companies, pay for research and development (R&D) of new drugs, hence the “justification” that we in the United States pay more, which is BS. Consider yourself lucky that you live in a country where GLP1’s are affordable.
The trouble is that when selling us bandaids makes rich people money. But solving the systemic problems causing the illnesses would lose rich people money. We’re probably never going to get past the bandaid
The video was a bit deceptive in regards to losing muscle mass. These drugs cause a decrease in muscle mass and bone density. You will notice that the video mentions losing something around 4% of your bodymass on these drugs. Notice that it never says how much actual body fat you lose.
I have rheumatoid arthritis, when I stopped wegovy, the symptoms got so bad (despite not changing my healthy diet) that my doctors gave me very bad news. Three different drugs to stop the rheumatoid arthritis, nothing is working. I’m back on Wegovy, now my symptoms are calming down again. I don’t know why. We don’t know why.
@ Hey! Yeah no. I did fasting for years and no, it does not work. Prayer also does not work. You’re talking to someone raised very conservative with parents who mentioned exactly that. Don’t you think I would’ve done all of that before paying $1500+ per month before my insurance kicked in lol.
@texasgermancowgirl forgive your parents because they made mistakes. Please. Prayer does not show if you can not see it. It is there. You are fasting when you take the medication, there is an allergy that is attacking your cells. Foods are compounds broken down in our digestive tract. You are fasting. If it is helpful but hard to get then God is helping but there is opposition. Your parents tried ma'am. They cared. Take God out of the box they put him in and find who is he for yourself.
I was ready for a fight in the comment section seeing the thumbnail. I was pleasantly surprised to find a quite reasonable discussion and insightful questioning into the topic. Thanks for an informative investigation and rational take.
This was an advertisement for Ozempic, pure and simple. The cost to produce it is less than $1.00 per dose and the pharmaceutical companies are bankruptcy health care plans.
I used my savings to be on ozempic for 3 months. I lost 15 lbs but the food noise being quiet changed my life. For once I was like ‘damn, this is how normal people live without being controlled by food?!’ but I couldn’t afford it. $400 a month out of pocket. I wish so strongly it was more affordable.
Trym health is a compounding pharmacy that offers 3-4months of the medication for about $450 in total. That’s where I got mine. It’s as legit medication. I’ve been on it for about 3 months down almost 20lbs
Ive been on it for almost 2 years. Ive only lost about 35 lbs. But my stomach fat is melting away. I do walk and workout also. This has been a great option for me to get my blood sugar in check. My A1C is better than it has been in years. A bonus is that I no longer want alcohol and save a lot of money on groceries and chasing food cravings. To do this day, I cannot kick the ice cream habit though.😊 Since I need this drug, I pay nothing for it. Its 100% covered by insurance.
What a lot of people don't talk about is that in the studies, up to 40% of the weight loss is muscle mass. Then the weight that is regained is usually adipose tissue (fat) which leads to a condition usually only seen in older people - sarcopenia. Your overall body composition is far worse off and I fear this will lead to an epidemic of osteoporosis, fractures and frailty. Time will tell.
But the muscle mass loss isn't any more dire than in any fast weight loss, a person would get the same result with losing weight with bariatric surgery or fasting. So your point isn't relevant for the video.
@@Emmuzka Incorrect. With a decreased caloric intake the muscle mass loss was due to lack of physical activity which wouldn't be the case with someone who loses weight with proper diet AND exercise. Also, the average loss of lean muscle mass after bariatric surgery is approximately 12 percent, which is significantly lower. Less muscle mass leads to a lower resting metabolic rate. As a physician who actively practices and discusses these issues with patients I can assure you I know the data very well. To that point, intermittent fasting was shown to increase the risk of cardiovascular death by 91% so that's another area of considerable research currently.
@@SinisterMD Interesting. Can you link me a study where the significant difference of 15% from bariatric surgery and 40% from GLP-1 mediacation can be seen?
As someone that naturally lost 180 lbs in the past 2 years, I only heard about Ozempic last year. I had a friend start taking it and she lost an average of 8-10lbs per month, at the time the same rate I was loosing. So we had a super open Conversation about what she ate and literally everything she ate calorically was the same as much as me. The difference is while I was eating and The difference is while I was eating in a calorie deficit and high-protein. She just at less. Less volume food. and was eating Half the amount she usually ate. While my diet was calorie deficient and high volume food I was still very hungry throughout my diet. and still am to this day. This medication basically takes into account willpower it makes it easier because it helps you not feel as hungry.
They mention in this video that there's a worry about losing muscle on Ozempic, but it was a little bit brushed aside talking about how if you lose weight through diet and exercise you'll lose some lean muscle mass. I've seen a dietician talk with somebody on Ozempic about their diet, and she was saying the person on Ozempic needed to up their protein to maintain that muscle, because muscle is good for you. If somebody is just eating less of everything, and not looking at what nutrients they're taking in, I can see this having a much greater negative effect on muscle than if they do what you did, which is something I would worry about. I've worked really hard in the past few years to put on muscle, to help with my arthritis and my long term health - I wouldn't want to lose weight but sacrifice that muscle, because that feels ultimately worse for me in the long run than not losing weight but having more muscle than I did before I started strength training, especially if you regain a lot of the weight after taking Ozempic.
@ like 4-5 month into I started I’m eating 1g of protein per pound of my goal weight. Ya super important everyone needs to that if they are on these drugs. It should be the most important part of the diet
@@ChantelleHale I am on Monjaro and I am generally maintaining muscle. It is effectively impossible to lose significant weight and not also lose some muscle, however, my primary form of exercise for years has been weight lifting and I am simply continuing to do that. Most people who go on any calorie deficit eating plan should monitor protien and add some form of resistance training.
@@ChantelleHalecertain muscles are simply less necessary if you are lighter. If you’re obese you need good strength or you will have major back issues etc. Being obese is like permanent, enforced weight training. So all else equal, you will lose muscle when you lose a lot of weight because you’re training it less. You can offset this by increasing your weight training.
People, stop accusing others of "cheating" weight loss by using Ozempic. First, you could be dead wrong, and the person might be losing weight because of chemo, an illness, or something else. Second, they should not feel obligated to explain how or why they lost weight to you. In fact, let me make this real simple: just don't comment on other people's weight.
You're right however it's a valid question when influencers push their diet teas and workouts but actually take a weight loss drug to get their results.
actaully your weight is everyones buisness because it effects society on a massive scale. it doesnt just effect the obese person or malnourshed person but everyone around them too.
@VladaldTrumptin Gatekeeping health is so bizarre. I went from 250lb to my ideal weight of 160 with diet and I don't have a problem with people using Ozempic to do it because why the hell would I? People cry about how unhealthy it is to be fat and that people need to lose weight. Then when people lose weight suddenly it's not about the health, its about not losing weight 'correctly.' People just love putting people down in any way they can. It's just a shift in bullying. 'Oh we can't bully you for being fat anymore but we can invalidate your accomplishment and make you feel worthless some other way.' It's pathetic.
Ozempic saved my life. I had diabetes and a genetic cholesterol of 300. Both are gone. I’ve been on it for two years. I was 140 pounds and ate low fat, low sugar. I had a heart attack at age 50. Statistically I had an 80% chance of dying after one heart attack. Six years later I am still here and healthy. 130 pounds, cholesterol of 100, and excellent glucose levels. Starting Ozempic was the only change.
the endocrinologist i saw to discuss taking ozempic was very candid and pointed out that ozempic might be dangerous for patients with depression: he said some of his patients who had depression reported that being on the drug heightened their suicidal tendencies which made me decide that i didn't want to roll the dice to try this drug.
This is super interesting. I wonder if there's a chemical reason or if it's as simple as food being a source of joy and taking it away can make those who already struggle with depression even more miserable. One of my friends who struggles with depression went on an ozempic type medication to lose some weight and it made her feel full constantly, to the point where even though she knew she hadn't eaten in a long time, the thought of having 1 bite of anything made her nauseous. She was on it for 3 weeks before she decided it wasn't worth it. She's also one of those girls who's 10-15 lb.s overweight and thinks she's humungous so she didn't have much weight to lose anyway haha, not sure if that has something to do with it too
I’ve heard this, but from the perspective of since the drug makes people ignore hunger cues, it makes depressed people who already struggle to eat or eat healthy more likely to just not eat at all and starve themselves, which I guess technically is a suicidal ideation…
I've also heard this. On the flip side, I've heard that with some people it helps with depression. Speaking firsthand when I started taking Mounjaro for Type 2 (tirzepatide, not semaglutide), my chronic depression eased and my "normal" mood was more neutral than depressed. I'd previously tried antidepressants and cannabis. Neither option helped me and both had unpleasant side effects. On Mounjaro, it was easier to find happiness in things besides food (and I even developed a disinterest in food. Food has been my drug of choice for over 20 years and just like that I had lost interest in it.) I was so surprised how Mounjaro helped my depression even before I had lost any weight... I didn't expect that.
@@garou12 as someone with depression who’s currently on zepbound, I will say, the first couple months were extremely tough. I’ve always used food and alcohol to push through those severe depressive episodes, and when I got on the drug, food did NOT help. It was always a coping mechanism for me, and I remember being EXTREMELY angry that food no longer brought me any kind of joy. Thankfully my family was there to help me through it, and so far, it looks like I’m on the other side of that problem (at least, for now), but it was scary for a few months there. The plus side is, now I have healthier coping mechanisms, but getting to that point did, admittedly, feel dangerous. It’s also been extremely helpful in reducing, and nearly eliminating my dependence on alcohol. I’m glad your doctor warned you about that potential. Mine did not, he just said I wouldn’t want food, and made no mention of WHY I wouldn’t want food.
I got an Arby's commercial at the end of the video. One of the many additional problems Elizabeth McCauley briefly touched on in this video. Great reporting McCauley!
If you've trained your brain to expect that speed, that's possibly setting you up to be impatient and rude to people in the real world who talk more normally. It's (ironically, given the subject of the video) a bit like wolfing down fast food rather than just appreciating a meal.
I started Ozempic about 6 months ago to lower my blood sugars, as they were about double what they should be. It lowered them to normal within the first month and has remained the same since. I did lose over 30 lbs. as well, but that was not as important as the blood sugars. I still lose at least a lb. a month, but I eat the same as before I started the Ozempic. I am not on any type of diet and eat whatever I want. My sugars are still good and I am slowly losing weight. This is all that I care about. If the only reason you are on it is to lose weight, you will fail. It seems to me the initial weight loss is due to the reduced amount of sugar to you cells. Once your body adjusts to the new level, the weight loss will slow to a crawl. If I did cut out sugar and carbs, the weight would start to drop drastically. I am old and want to enjoy my remaining years by eating anything I want instead of dieting. It took me 15 years to put on the excess weight, so I am expecting it to take that long to lose it. No worries, no stress, no dieting, that is what I am doing to enjoy my life. Lower your expectations and you will succeed.
*12:20** You are so right about the punishment. People WANT to believe that those who succesfully lost weight will experience these dreadful side effects because they hate the idea of weightloss being a bit easier*
Because American subsidize the lower cost in the rest of the world. If america had govt regulated pharma pricing... All pharma prices would go up globally. You really think AIDS meds in africa cost only $1? They give the drugs away to poor nations at a loss, because they recoup it in the US @ $1200 per pill.
I take it for weight loss. It is not an “easy way out”, it is a game changer. Feels like a miracle. The side effects hit hard, but I had them only for two weeks (max dose, no ramp-up). Important anecdotal details I have not seen covered: 1. It does not work the same way for different foods. For example, I am physically unable to drink an entire cup (sometimes half) of coffee now, but pizza? I could just keep going. Of course, I don’t because it would make me throw up the next day, but the medicine doesn’t help. Most likely this is different for different people. 2. It helps a lot with self control, but also requires a different form of self control. Sometimes, I have to remind myself to eat when not hungry, because if I go too long, it triggers side effects. Other times, especially the day before a dose, I no longer feel the effects so I have to control myself or suffer the side effects 2 days later.
The will power part really helped me, the amput of food i have rejected with no remorse afterwards, also my choices regarding food, since i know i will be full after eating a bit, in choose to est more nutrition densed foods
I simply want to say that the host Elizabeth McCauley presents extremely well and clearly, and the subject feels like it was analyzed in depth. An "S-tier" host, as the kids would say.
I’ve lost 175 pounds (40% body weight) on Zepbound and eating low carb over 2 years. I’ve dieted my whole life and never had these results. These drugs ARE a miracle for many people!
The same results can be achieved through diet and exercise. If the drugs are staving off your cravings then as soon as you stop taking the drugs then youre likely to regain the weight unless youve done the work to curb your cravings yourself. So these drugs are only a temporary treatment to what are behavioral issues. They shouldnt be used by people without a specific reason to do so. Weight loss isnt a good reason to use them.
I lost over 100 pounds without it, but I was put on it for type 2 diabetes. Losing weight is definitely easier with it. I don’t think about food constantly like I did before. So before I had to have huge willpower to lose. Now it’s just a thing. It’s dropping off without trying.
@@supernova743 This is simply inaccurate for a huge swath of the population. You'll find countless examples in this comment section, myself included among them, of people who've used diet and exercise to lose more than 100lbs, and at no point in that journey do you ever lose the cravings for food, whether nutritious whole foods or processed junk food. I'd cut processed food out of my life years ago, and I STILL gained weight, because I'd sit down to a bowl of curry and rice, and have seconds, and thirds. The most processed thing in that meal was the flour and the white rice. My body/mind found joy in eating. It could be a whole chicken i roasted myself, or a steak, or mashed potatoes made from scratch, all of it brought me joy. When I lost the weight naturally, the cravings for those foods still existed, even white rice, chicken, and broccoli would make me happy to the point where i could consume so much of my "healthy foods" I'd still gain weight. On zepbound, it doesn't just "stop your cravings" it changes how your mind/body regard food. For many people, food releases dopamine. Again, not just junk food. I'd be elated eating plain chicken and rice, to the point where i could consume pounds of both in a sitting. Now, I can take a bite of my favorite foods, curry, steak, sushi, whatever, and feel...nothing. The first few months on these drugs is often frustrating for people because they've spent their whole lives finding happiness at the end of a fork. It's often the most reliable dopamine release people have, and from literally day one (in my case), it vanishes over night. I've become more social with both friends and family as a result, because now that food doesn't make me happy, I HAVE to find that dopamine release somewhere else, and that somewhere else is a much healthier place. I spend more time hanging out with my friends, or spending time with my family, because I have to. I don't have any other sources of dopamine. Food just stops being a source of happiness, and because that's the case, you not only stop eating junk food, you also, often, stop drinking, and you also eat significantly less of even your healthy meals. Now I can sit down to a bowl of curry, eat a single serving, and walk away without a second though. I've been able to FORCE myself to make that choice, but now, my body WANTS to make that choice. That simple difference is liberating, and if it's not a struggle you or someone you love have ever been forced to endure, it's really difficult to find empathy for those going through it. The facts are that, while you're on the drug, you develop a non-destructive relationship with food. You know you need to eat, and you do still, but you don't have a desire to snack, you don't have a desire to overindulge, and you no longer find happiness in food. So yes, you can, and I have, seen similar results with willpower and exercise. The difference is, every day is a mental battle. It NEVER gets easier, and you ALWAYS lose eventually. It may, and in my case, did, take years to take that L, but it does happen, because the entire time, food was always sitting there as an easy out in a stressful situation. It was just election season, a really stressful time for a lot of people, and for me, and at no point, did food EVER seem like it would ease that stress, and that was liberating for me. I expect I'll be on this drug for life, just like I expect to be on anti-depressants for life, and previously expected, and still may, to be on statins for the rest of my life. I'll probably see the same physical results that I've seen many times in the past, where I get down to a healthy weight (I've been as low a 165lbs at 6' tall with 0 drugs), but this time feels different. I don't have to argue with myself about portion control or whether I should go down the chip aisle at the grocery store. I don't have a desire to over eat, and I don't have a desire for snacks, and it's the first time in my 20 years of being an adult that I can say that.
@@supernova743are you really trying to say that someone who used to weigh 425 pounds shouldn’t use whatever tools necessary to loose weight? You are a fool and clearly have no idea what it is like to struggle to loose weight. My results have been achieved with GLP1 *AND* diet and exercise.
On 11 June 2024. I was 101kg and started mounjaro, changed my eating habits and started exercise daily. I reached 72kg on the October stoped it, I kept exercising and eating less and I didn’t put any weight yet. I really happy and feeling a new person
You're not just being lied to about Ozempic. You're being lied to about nutrition in general. The average North American still thinks fat makes you fat and eating cholesterol causes high cholesterol.
This+ the prices of processed foods compared to Whole Foods like fruit and veg… I’m American and lived in Japan half a year and while my diet in terms of foods/amounts didn’t change much, just the amount of more Whole Foods and less processed junk really made a difference. Came back to the U.S. and my stomach was not happy ://
They best way to prevent these diseases is to eat right. We are in the era where our food are grown with fertilisers, sprayed with insecticides and are no naturally grown. Water to drink are not safe for consumption, we breathing in toxic air. The solution is to eat right.
Eating too much cholesterol does cause high cholesterol... No one is lying to you regarding this. Just because you changed ur understanding of things doesn't mean the world perceived things the way you did before you fixed ur misunderstanding. Stop projecting ur ignorance.
This vid is weirdly very skeptical of negatives, and extremely permissive of completely anecdotal positives that have zero evidence behind them. It is not well balanced at all, and towards the end it becomes clear this is a sponsored piece. Disappointing this was not said up front.
I have to agree. It wants to appear balanced but just sort of brushes off the negatives. For example, it starts off with the, admittedly false, "No" studies for non-diabetic weight loss claim and just says "Well actually there have been studies" and then moves on. Ok, but how long have these studies gone on? Everything that I can find dates only to 2016 (for wegovy studies, with wegovy being approved in 2017). That IS very new. Lots of drugs get approved for a particular use, and then the true impact of side effects only becomes known over 10, over 20, etc years later. We're just coming up on the first 10 n year mark. The non diabetics being given this over the last 7/8 years ARE the test group for the long term effects. Will long term effects on non-diabetics being miniscule or harrowing? I don't know yet. Maybe there's no big worry. But this video just sort of mentioned "yes there have been studies" to discredit the exaggeration of "no studies" but doesn't admit the lack of Long Term study data. Kicking off with that makes me very skeptical of them treating both sides objectively.
"They were restricting their calories. They were following diet. They were exercising and it just didn't work." Congratulations, someone just found perpetual motion.
Remember that the body is complex. When you eat less, your metabolism can drop to lower levels. It's not "perpetual motion" it's "we don't know all the inputs yet to this problem."
@@jreese8284 I fully agree, body is complex but do not try to make this a problem with impossible solution. Yes, there can be huge differences in calories consumption per day. Two persons with the same age, weight, sex, can consume between 1500 - 5000 calories per day. Yes, when you lose weight, your body uses less, but at this point you have already lost weight. So it's time to rebalanced tour diet. What would happened if this person who "can not" loose weight would have strictly controlled diet, for the sake of the conversation let's say in prison. And if this person can not loose weight in a month, it's time to reduce the calories. There is no way this can not work. Ozempic does the same thing. It's lowering your appetite. You eat less > consume less calories > your body is loosing weight.
The real issue that isnt delved in too much is the fact that these drugs are not new. and yet they are sold in the US at incredibly high prices (at least when it comes to list price). Americans need clarity on pricing. I doubt insurance companies are paying over a thousand bucks a month. but those without insurance need to, and these are the people who may tempted to go to shady online pharmacies
In America you can’t have “freedom” without allowing huge companies to overcharge customers, duh. Freedom isn’t free, it costs 100x as much as it does in Europe bc you gotta please those shareholders!
It makes sense that people stop taking it after a year. No insurance covers it and the manufacturer coupon only lasts for a year. It’s not because people don’t WANT to be on it.
One thing I noticed about most of the people who advocate against semiglutide have never been fat or addicted to food. I said SOME not all. I’ve been overweight all my life and recently became obese. This is the highest my weight has ever been. I believe I do use food to cope. Not only that my genetics. Diabetes and heart disease and obesit, even cancer is pretty much my whole family. I’ve lost many to these diseases. This is my fear which is why I took the step and was prescribed wegovy by my doctor. However, in order to keep receiving this medication I have to keep appointments with a nutritionist and a fitness instructor. I’m blessed because my tribe provides all of that at no cost to me. So far I have lost 20lbs so I would say this drug is working. It’s easy for me to say no to unhealthy foods I used to love. Sometimes even thinking of it makes me sick. This is journey I’m willing to stay on for as long as I can.
Same. There’s two major problems with processed food that contribute to weight gain: the body burns through them too fast, causing you to feel hungry again, and they don’t have a lot of the micro nutrients that you needs in addition the calories, requiring you to consume more to make up for the deficit.
@@AWriterWandering Another thing is that many ultra-processed foods contain sugar, a natural addictive drug. Sugar increases insulin and hunger, which causes you to want to eat more, and is a big contributor to obesity. Check the label next time you're at the store, and you'll be surprised by just how much sugar is in almost every food.
@@Persistence_run_444 I’m sure that avoiding processed food was beneficial, but if you were already at a weight where you could “pick up marathon running” you were no where near the size that you would have any business being on one of these drugs, regardless of how much weight you lost. So, your comparison is moot. Weight loss for a person in an obese/morbidly obese body has already gone through hormonal dysregulation.
I went on to lose weight so I could qualify for a breast reduction (I live in a place that is only now getting rid of BMI requirements). Now I’ve had that surgery, and being able to be as active as I’ve always wanted to be and scaling down my shots because I’ve essentially lost my appetite and I’m not eating enough for my body to stay out of starvation mode.
after having been on medication that either increased my appetite, decreased my appetite or made me gain weight regardless of what i was eating, it's become so obvious that all these things truly can be out of our hands depending on how our body works at any given time. people who have naturally lower appetite, or fast metabolism tend to think "well, if it's easy for me to maintain weight, it must mean you're just not trying hard enough" but that's so wrong. i hope we can finally move on from fat shaming and instead focus on understanding each individual's issue that's causing it so it can be addressed
@@SF-eo6xf there's also no such thing as a fast metabolism. a drug that makes people eat less causes them to lose weight. in other news, water makes things wet
ignore the dumb assholes, you're absolutely right. Several scientific studies have shown most weight loss people experience trough exercise and dieting comes back within a year. Weight loss isn't achievable for a lot of people, and additionally is frequently detrimental to people's health. Caloric deficits have been shown to lead to a plethora of health risks associated to stress on the body.
While I think the title of the video is a bit clickbait at the time, "You're Being Lied to About Ozempic", the video itself is really good I feel. It goes over a lot of the potential misinformation seen online or in the news about all the dangers, while also taking about the actual dangers of the drug/compound version of the drug and as the fact that it's not a miracle drug and that it doesnt always work for everyone. And talking about the bigger issue of weight lost and health too and how exercise and how complex it is, that also was good information to have in the video to complement the information about the drug.
Why is it when a device is invented that saves lives or makes life more comfortable noone has a problem with the manufacturer making money, but when a drug does the same it's seen as almost criminal?
I think it’s mainly because, as you said, these drugs save lives. And the problem is not companies making a profit, the problem is companies being “greedy” and gatekeeping the drugs/treatments in order to make larger profits. Don’t get me wrong, I’m 100% pro-market lol. But I do agree that sometimes, with stuff like this for example (drugs that can substantially improve the health and well being of hundreds of millions of people that have a medical condition like obesity), these companies (more like their owners/shareholders) have the moral obligation to make the drug accessible to as many people as possible. I mean, they have already covered the cost of production and research SEVERAL times over, everyone at novo disk is already rich asf, generational wealth kinda rich. Is it a bit unfair to them? (because they invested a lot of money into the research and development of something that could not work at all and fail) Absolutely, it is unfair! Yet it did work, and they did get richer than they already were, and they can still keep making more money (just not the absurd amounts of money they are currently making) That being said, there’s also many people who are just conspiracy theorists and are convinced “big pharma” is out to get them lol
It's not that they make money, it's that the cost is significantly more expensive in the US than it is worldwide since they can get away with it and thus prevents many people who may need it from affording it.
You are presenting it as a binary choice, either the drug companies make "no money" or "all the money". I suspect that they could lower prices substantially and still make significant and worthwhile profits.
If people could get it on copay I think people would be singing their praises and thrilled they were getting rich. A lot of people can't, which is baffling.
5:16 for me it was harder to lose the weight. It’s been easier to keep it off. I lost 70 pounds on my own over six months. I weigh myself every day and adjust my diet accordingly.
it's always strange when people equate "not easy" with "doesn't work" with regards to losing weight. I think it should be made clear that for the people where lifestyle changes "doesn't work" that the juice, for them, wasn't worth the squeeze. No shame in that, but saying it "doesn't work" is wild af. That is a crazy level of a victim mentality.
18:10. I call BS on what he says here..."They were restricting their calories"...and didn't lose weight. Were they really restricting their calories or did they SAY that they restricted their calories? There is a difference.
I was obese and not eating that many calories and not losing weight- but I then instead stopped eating sugar and stopped eating processed foods, and I lost 55 pounds in the past year without calorie counting at all. It can be more complicated than just calories. Eating low calories of processed crap did me no good.
I've been taking Trulicity, which is similar to Ozempic etc. for over a year now. I haven't lost any weight while taking the medication, but it has been really helpful in managing my Type 1 diabetes. Even though it is technically for Type 2 diabetics, it has helped to keep my blood sugar from spiking drastically after meals, and that has been great because large fluctuations in blood glucose can mess with my cognitive ability and make me feel sick, so it has definitely been worth it even though I haven't lost any weight on it. (edited because I mistakenly wrote Tresiba instead of Trulicity)
Tresiba is insulin dear. Totally different mechanism of action than GLP1 agonists. Insulin may in fact cause weight gain. Do you mean trulicity? Anyway, cheers and happy losing!
Destruction of physical labor in favor of desk jobs along with the rise of chemical riddled fast food has created the obesity "epidemic". Companies now want to capitalize on a problem they caused by forcing you to pay money to lose weight. Instead of, you know, improving the work place environment. Which they never will, because that would mean a decrease in perceived "productivity" and extracting every ounce of labor from employees is how companies operate. Let's also not get into how these transition from analog to digital has made people lazy to the point where they'd rather rely on drugs than make the effort to change their lifestyles. Because "effort" is too slow and people want instant results even if the results are harmful.
My biggest concerns are that it's replacing a hormone which has natural on/off cycles, and it's doing it by basically flooring the gas pedal. Let's hope that signal isn't a growth factor for cancer, or a trigger for some other dire medical issue. And to that second bit, in some people, it slows down the gastric tract in a way that doesn't seem to stop when they stop taking it. That can be good, if the result is therapeutic. It's a disaster if it's too slow, and it seems to cause, what appears to be permanent, gastroparesis. Additionally, the body composition of people losing weight from it appears to be 50/50 fat mass and lean tissue. This is equivalent to the body composition changes associated with starvation. Which means that basically it's just "regular old dieting" and if you stop taking it, and it's effects wear off... You're right back where you started.
"Let's hope that signal isn't a growth factor for cancer, or a trigger for some other dire medical issue." For some of us in the super-obese category, it's a fair trade. I've dropped over 110 pounds in a year on tirzepatide. Without losing that much weight, I was very likely to die of some weight-related issue and quite young. Neither of my (obese) parents lived to see 65. If I get 20 years of far more active healthy living than I would have without and then some nasty cancer from the drug at 70 and die? Guess what, that's a total WIN, not a disaster.
@@MostlyHarmlessNebr-gb6di that's great, and I'm glad it's worked out. And I hope it continues to work out for you in all possible ways! They are incredibly interesting drugs and can be helpful for lots of people, and they are also teaching us a lot about the biology of appetite/craving in ways we did not expect.
Thank you thank you thank you!!! Its been so hard to cut thru the noise and chaos to see any kind of truth about these drugs. Your reporting feels like the first time i have encountered something balanced and fairminded about the whole thing! As a PCOS sufferer who had a baby in my late 30s, weight loss is next to impossible. Despite being a lifelong runner, a running addict, and eating right! So my doc prescribed ozempic and then tried for monjourno which is the one helping specifically PCOS women. No insurance would cover it despite saying they would and after a year i gave up hope, resigned to the slow slide into obesity and diabetes - typical outcomes for PCOS sufferers. Then came stories of stomach paralysis and family said its good you didnt get the meds, but i still feel unhealthy and ungainly, and even with the side effects i would try anything at this point to feel like a healthy approach is rewarded with my body losing weight and being more fit. We'll see what happens. I still hope i can get the prescription someday, because we do not have $1,000 a month to pay out.
So as a guy who has psoriatic arthritis I can't really do enough exercise without doing harm to my own joints in excess of normal wear and tear. Yet despite that, me and being pre-diabetic, and obese my insurance refuses to pay for any injections. According to their own statements regarding coverage for semaglutide injections I have 3 different symptoms of issues that would qualify. So I'm struggling with my insurance that I can't get rid of to get a thing that I could actually use to help me lose weight that diet can't (basically it becomes the "exercise" part). It's completely frustrating to both me and my primary care doctor since nothing that's been used by either of us has changed a thing.
Look at any photo of a group of Americans from 1950, and you'll see virtually no bigger/overweight people. Now the obesity rate is near 50% in some places. You cannot tell me that people are bigger now because of "gland issues", etc. What did change? People are less physically active, portions are bigger, far more people have cars, fast food is everywhere. There are numerous other factors, like food deserts, people having less time to cook due to having to work more, pollution, etc. So yes, it's complicated, but it's also not. Weight loss is NOT easy. That's a fact. Anyone who says "just do XYZ" is wrong. That said, people tend to ascribe nothing to themselves. It isn't "I shouldn't eat 8 cookies a day", it's "no matter how many cookies I eat, I won't lose weight" which simply isn't true. I'm currently "carb cycling" to lose weight. On Mon/Wed/Fri I eat very few carbs. It SUCKS, but it is working, slowly. I don't think it's unfair to expect people to actually try actually difficult non-drug methods for an actually significant amount of time. But I've heard people say "sure, I eat a lot of sugar and I don't like veggies, but I just can't lose weight". You don't know you can't lose weight because, if you're eating lots of sugar every day, you haven't actually tried losing weight. You do not get to eat half a box of cookies a day and lose weight, that's not how it works. Now, if you've tried all of the methods, done the hard things, your diet is actually good, and you still can't lose weight, then by all means, try this drug. But the fact that one is essentially committing to be on it forever should by itself be a deterrent to saying "I tried a diet for two months and it didn't work so I'm taking this drug".
Fully agree, I highly suspect the vast majority of people are not telling their doctors or anyone the truth, that they simply aren't trying, I see it daily in my own home and in my community regularly. People just don't want to do the hard work.
If you have yo-yo'd several times, you can get to a point where your weight loss will be minimal despite all efforts. When you gain weight, you gain fat cells. When you lose weight, your fat cells shrink but remain. More fat cells = more hormones to ensure your body holds onto fat. I went through many cycles of this before I learned it, dropping weight and gaining it back, getting heavier each time. Now, even losing 20lbs is an exhausting battle (though I am sure getting older has not helped either). I go out of my way to warn people about this to make sure they don't get themselves stuck in the cycle. If you drop the weight, you better make sure you keep it off. Wish I would have known that in my early 20's when I got relatively fit and lean after being moderately heavy.
@@masaharumorimoto4761physicians are highly trained in many areas, but most have shockingly very little training (what amounts to a course or few courses at most) on diet and nutrition, unless they take it upon themselves to do continuing education in that area. Modern medicine is geared around treating chronic conditions with medications, and less so about strong interventions in diet or lifestyle. Not their fault, and we collectively as a society need to reform that approach on many levels.
@@Twosocks42, yes. But also the fear of yo-yoing is real. Yet another weight loss effort, from fads OR doctors, ultimately leads to increased weight, so it’s scary to even contemplate trying something else.
I've been on wegovy for 6 weeks now and the biggest change has been how not eating affects my body. It used to be that if I went more than 4-5 hours without eating that I became shaky (to the point of having hands tremors) and hangry (irritable, snappish, etc) Now the worst I tend to get even when I have to go 8-9 hours between meals* is a mild queasiness. It's allowed me to eat smaller meals (that don't make me uncomfortably full, as was my previous norm) because I don't have to worry about having to tide myself over for as long as possible to prevent The Hanger from taking over lol *I'm not purposely going that long between meals but I'm a fulltime caretaker to multiple disabled relative & sometimes between playing chauffeur to all their appointments and making sure they get their meals, I have to delay my own eating.
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"This un-biased video is brought to you by Novo Nordisk"
In 1986, I took a contract in Saudi Arabia. I lived in the Mojave Desert, so the climate was pretty much the same. When I went to Saudi Arabia, I worked pretty much the same and ate pretty much the same. I weighed 230 lbs. In the second 30 days, my weight started dropping at a rate of about 2 lbs per day. My employer was so worried, they sent me to a doctor, who promptly started testing me for cancer. Fortunately, no cancer was found. I ended up stabilizing at 165 lbs. When I returned to the US, my weight promptly went up to 230 lbs again. The only thing different I could identify was that the food in Saudi Arabia was locally procured. I am convinced that a great deal of the obesity in the US is the food additives.
I lost 225 lbs the "old fashioned" way, kept it off for a decade now, and I feel like trying ozempic to make the maintenance easier. Very true statement that losing the weight is the easy part.
I used cardio, weight lifting and diet to lose 25-30 lbs in 1,5 - 2 year's. Lost weight and gained muscle, no hormone medication needed, just dedication and a goal. Just a little more lbs of fat to lose.
I'd like to add that as someone riddled with a slew of chronic illnesses, I became desperate enough to start this about 5-6 months ago. I hoped that if I lost weight I'd get better treatment from doctors, and it would be easier to get further surgery for my dercums disease. The best side effect is my IBS is gone! I had constant daily diarrhea for two years, after five years of having it frequently. Since I'm actually absorbing nutrients and staying hydrated I feel so much better. The downside though has been the terrible cough from acid reflux. Neither of these was covered in the info about the medication when I started, so makes one wider what other benefits or side effects will arrise over time as more people report on it.
Well rounded research with a what felt like a bit of a bias for Ozempic. The systemic issues are incredibly difficult to overcome given the inconsistencies among nutritionists, the "organic food" lies and the kind of ingredients that processed food makers are allowed to use. The cultural issues are even worse when friends, family and workplaces create environments with incredibly unhealthy foods. Having a child really opened up my eyes when reading the ingredients on labels and I still have a lot of uncertainties on what I need to avoid.
I have had no negative side effects and have lost about 60 lbs in 7 months. I feel free and like a “normal” person even though I still have a ways to go on my weight loss journey.
This video took a turn…. It really spelled out how these drugs and drug companies take advantage of consumers but its okay to band aid the problem? Some one please explain.
I lost 27kg in two years of Ozempic use paired with a new diet and exercises. I went from obese to slight overweight and I cannot stress enough how my mental health, my self-esteem and my overall health improved. It was under medical prescription and monitoring, and our goal was to use the drug as a tool, not as a clutch. Thus, I’m lowering the dose in order to eventually phase it out and focus solely on exercises, but I cannot deny how transformative Ozempic was, the push it gave me to actually pursue a better life. And in all honesty, looking better is the good side effect for me.
The issue is simple and it's been simple the entire time, it's literally staring us in the face. OUR FOOD/DIET HEALTH APPARATUS IS ABSOLUTELY BROKEN. High use of meat in every meal, high use of simple carbs in every meal, low levels of fiber, low levels of fruits, legumes and vegetables. We are fed nutritionally deficient foods at every turn. Real food is more expensive than highly processed foods. We are constantly looking for an easy way out of the pit when ever year the obesity levels increase. There is no easy way out. We allow food lobbies to tell us what to eat and what is ok to put in food when their main aim is cheaper processes and more profit. It's literally killing the population off slowly. Real solutions Upend the system return to less commercial farming practices diversify the plate! Reduce the meat consumption bread and milk consumption. Increase the plant and fruit consumption. We are literally staved and fat at the same time... No one medical "miracle" will fix the issue. We always want the silver bullet there isn't one! Someone in authority needs to be honest!
True. What we eat is the most important aspect. Plus, the amount we eat. In the US, it’s so normal to eat crappy food until we feel sick from how full we are. We should never be so full, yet we do it everyday. That, coupled with the lack of exercise in most peoples’ lives… it’s just sad. They bred this.
You must be young and don't realize how we were feed back in the '80s / '90s. Food wasn't healthy or unhealthy, but we ate less of it. I grew up eating a lot of meat, milk, cheese, normal amount of vegetables and a lot of carbs. My Mom never fixed a vegetable with spaghetti. It was served with more carbs, bread. But, we weren't as gluttonous. Also, we just naturally moved around. It was watching TV, reading or go outside. I left high school weighing 135lbs being 5' 10".
Plus too much money is being made, this video in the end was still a marketing tool for Novo Nordisk's $500 billion market cap. The solution to trash health in scamerica is identical to what civilizations did for thousands of years, vegetables, fruits and being active. Aka burn more calories than you consume.
Meat isn’t the problem, in most cases it’s highly palatable foods/ drinks that aren’t satiating. Think chips, cookies, donuts, soda, etc. Meat, fruit, and vegetables are all much more satiating than processed food, so we naturally cannot overeat them. While fruits and vegetables are important for overall health, meat is critical for getting enough protein unless you are pounding plant-based protein powder every day. It helps to retain and build muscle which is critical.
@@Theoryofcatsndogs about 60 dollars in china, france, danmark and germany. here in brazil it's absurd. a monthly cost of wegovy is 2400 reais while a monthly minimum wage is 1400 reais. also no insurance coverage here, every pen is full price out of the pocket.
The biggest issue I've found is that there is no supply of low doses of Weygovy and that health insurance doesn't cover enough of the med Zepbound. Other drugs aren't approved for weight loss only, and providers will not prescribe other GLP1s. Supply issues and access to the drugs are a bigger issue.
I watched this entire thing. Everything about this sounds like a long commercial to sell these drugs. I wonder if Business Insider got paid by the drug companies?
This drug works for me. Of course everybody has different situation. My doctor put me on this med four years ago for my fatty liver which has caused my liver fibrosis. Lost about 32 lbs in four years gradually. My fatty liver is reduced dramatically. For decades, my recent blood work shows my liver numbers in normal range for the first time. My blood sugar is also under control now. All meds have side effects. We need to look at what individual situation is. You cannot stop eating just because you got chocked.
I lost 30lbs on a compounded GLP1. For me, the drug helps with addiction. I always had food noise and was thinking of the next meal. That noise has gone away. When I am comfortably full I can "push-away" the plate of food. I also developed sleep apnea which is not cured, but under control. Due to the lack of sleep I drank a lot of caffeine. After 1 week on a GLP1 i drink maybe a 1/2 cup a day now. Others has reported decrease in alcohol consumption. I was never a big drinker.
I'm really confused, because the thesis seemed to be that we need to turn down the hype, but all the supporting detailed seemed to confirm it was worth the hype.
I think the idea is to turn down the extreme-hype from "omg miracle drug" down to a moderate hype of something like "These drugs work decently well". Something can be overrated while still being functional and useful.
Because it works and they don't want to have to pay medicate costs for an obese ageing population when there is a medicine that helps reduce their over all costs. The US is partially socialized medicine, and the gov wants to use drugs that save them money in the long run. Even though what we really need is better quality food becuase food in the US is shit.
@ I don’t think I can add links here. But there’s a video on TH-cam about how ozempic is very very expensive for a medicine being used as a preventative.
@@kutie216you have a theory and you apply it whenever you see mention of drugs. Simple world view. It’s possible it helps many, many people AND pharma companies are not good actors. Hard to keep two things in brain at once? .
We just need to start treating addictive junk food the same way we treat cigarettes. Health education campaign, banning them from schools, warning labels, and heavy taxes that can be used to offset the healthcare costs. Instead, our government literally subsidizes these addictive foods, making them cheaper than real food.
I tried metformin and got horribly dizzy couldn’t take it. Trulicity gave me hives. Ozempic worked great for me. Ultimately everyone is different and you have to find the right thing for you.
I've gone from 233 pounds to 188 pounds and from A1C of 9 down to 5. All of my markers have improved and I am no longer taking any other meds, including insulin. I also began working out with weights a year ago and look better now than I did in my 20s.
I appreciate what you reported I can also say that like most journalists you don’t understand research. Citing the conclusions of papers is meaningless if you don’t look at the validity of the study. I will point just one of about 5 examples I could cite. The first study you looked at that says the average loss from exercise and diet alone is only 2.4% That means that the people in that group did NOT actually follow a VALID diet and exercise program. Unless of course you believe that diet and exercise can only shed 7 1/2 pounds from a 300 pound person. That obviously is nonsense therefor making the study nonsense. The only study that would compare how well ozempic works would be to compare how a REAL diet and exercise program, one that is followed, compares to using Ozempic ALONE. Don’t look at the results after 6 months because that is meaningless unless you plan on being dead in 6 months. If you don’t change your eating habits nothing works long term, and that is the only message that helps people.
10 minutes into the video, it sounds like an guerilla marketing campaign for Ozempic especially now that the sales have plateaued and soon we'll have generic versions.
She was literally prescribed a generic version, which she shows on camera. Two of the main messages are that it doesn't work in the entire population and that you will probably regain the weight after stopping the medication. Certainly not the best advertising campaign for a company.
I just started my treatment about three weeks ago. I’ve lost 6 lbs. My hunger has decreased, but I’ve noticed that my mind keeps trying to tell me I should be eating. It’s a battle I have to fight everyday at least now I’m not also really “hungry” all the time.
I started using Suxenda about a year and a half ago and barely saw any results and the fact that it required a daily injection was just too much for me especially with the severe GI side effects constant nausea and about 1-2 vomits daily with no real benefit then I switched to Ozempic which was very similar in results but at least it was a once a week injection so it wasn’t as bad but the real game changer for me was Monjaro (Tirzepatide) it had much less side effects and a much more pronounced weight loss. So the moral of the story I guess is that for those who don’t see results with a certain drug maybe consider trying a different one
This craze for these meds has meant for that over 2 years I have to ration my medication because I was put on it for diabetes when other meds didn’t work. They are harming diabetics I order to lose a few lbs. The shortage is less bad than before, but please don’t push it for other things. It’s a lot more dangerous for someone who can’t get their blood sugar under control because of the shortage than it is for someone who is sad they can’t have a baby or who wants to lose a few lbs.
I did 2 cycles of Ozempic .5mg a week with 45 off days in between each cycle. I lost about 18lbs but I now have severe gallbladder cholecystitis. My doctor has recommended I remove my gallbladder but I will first be trying some natural remedies and dieting before going under the knife. Just thought I would share my experience. The pain is just unbearable!!!
The food noise comment is real. When I first got on zepbound I remember being angry that I didn’t enjoy food anymore. No meal made me “happy”. And after a few months I started to realize “my happiness isn’t tied to food”. That tiny shift in how my mind thinks about food was a real game changer. The difference between “I don’t feel happy eating food” and “I don’t need to eat to be happy” is STAGGERING.
There are chemicals in food that form compounds in our stomachs. Sugar and gluten form a compound similar to morphine. It is a pain killer. You did not take a weight loss pill or shot. You turned off the addiction part. Those compounds. Stop taking it and you are still addicted. Healing takes time and work. I thank you for your work and may you continue to live and be happy. With or without food. Your body is yours and no one should be able to say it needs to be different. It is just soul clothes and nobody looks the same but all of our souls do. Your clothes are fine.
It's just self calibration... When I've been on Keto for even a WEEK, a candy bar tastes DISGUSTINGLY sweet. To the point I would need to force myself to eat it. But ANY ripe fruit would smash that candy bar easily... Only once you start getting back into junk/sugar do those tastes begin to shift again...
@@mcbrite It really isn't. You talk like I haven't lost more than 100lbs via willpower alone, or 60lbs via keto, or multiple other diet trends. The difference between zepbound and the normal "diet and exercise" advice, in my personal experience, is that NO food produces a serotonin/dopamine response on zepbound. When I was keto, a steak was still a "happy" meal, as was a rotisserie chicken. When I was calorie counting, everything was still a "happy" meal.
On zepbound, my favorite foods, like curry, or steak, or etouffee, or sushi are all just sustenance. I have no desire to finish the meal, and often don't. I get a few bites in and often decide to just put the fork down because I don't want it. I'll go to a gas station, and just get a drink, and skip the chips and candy, because they don't seem appealing.
Heck, even alcohol is significantly less appealing, which is just another benefit to my health. No matter what diet I was on previously, there was always room for a few ounces of whiskey a week. I don't even want that anymore.
What I'm trying to say is, my whole life, food and drink have been my PRIMARY source of dopamine and serotonin, and now, for the first time in my adult life, they're not. They don't give me that feeling, and it's forced me to change how I live, not only with regards to food, but also my personal life. I had to find new sources of happiness outside of food, and I'm a better PERSON for it.
Everyone's different, and your results with controlling your diet very well could have produced different results than my own, but to discount it as "it's just self-calibration" doesn't just attempt to discount my own personal anecdote, it also seeks to discount the actual science done studying how the drug functions and it's impacts on those taking it.
I had already lost over 100 pounds before Ozempic so my mind shift had already happened, but the food noise thing is real. I still had tons of food noise and Ozempic had helped a ton.
First of all, all weight loss and a lot of anti anxiety/ssri’s meds have serious life altering/destroying effects on you and their effectiveness rarely makes up for your suffering‼️
Be very careful. These meds have a short term use benefit, ONLY short term‼️
Both of my parents are overweight and diabetic. They were both put on Ozempic. It seemed to work well for my dad, but my mom never got past the initial low dose phase. She got severe gastrointestinal pain and vomiting. So I can see how the drug is not for everyone
Great that she stopped taking the drug, unlike the lady in the video who preferred vomit to death.
@@Intoxicatious there’s not a single drug on earth that is for everyone. Even ibuprofen.
Biology will teach you why. Nature wants to increase diversity and change.
have your mom check out Retatrutide. It's got less severe side effects and is VERY effective
Each drug is different. Some can’t tolerate Ozempic/Wegovy, but can take Mounjaro/Zepbound.
GLP1 peptides are pro nausea. GIP peptides are anti nausea. She should switch to tirzepatide.
I initially took ozempic for weight loss however only lost 25lbs in 11 months. However after 20+ yrs as a diabetic I officially have it controlled. I'm no longer injecting insulin 4x a day and no more Metformin! I've had no crazy side affects and blessed to only have to take a once a week injection!
insane results, well done!
I hear you sister. With the body of a college athlete, keto diet and exercise, I could not control my DM2 until Ozempic arrived. Of course, I am using prescription compounded semaglutide as insurance won't approve Ozempic because I do not have "complex" or "multiple comorbidities" - I eat too well and exercise appropriately.
25 pounds in 11 months is nothing to scoff at! That’s still incredible and a large amount of weight. Give yourself some credit cuz you deserve it, and nice job on getting your diabetes under control!
Good job!
I did a wegovy course and lost 54lbs in 6 months. Have been off it now for 6 months and am still down 48lbs with almost all the regain being the first two months off it. I am no longer fat enough to get the insurance to cover it again lol.
damn thats impressive, good job.
So what you're saying is that the insurance system is structured to *guarantee* the "yo-yo effect." The drugs are designed to be used indefinitely, but insurance is designed to resist that usage profile.
Do you know how much muscle you lost?
No they are saying the weight largely stayed off.
Yes damaging your digestive system to freeze up… is perfectly fine? What do we do about all the impulsive fat slobs? Give them receptor agonists…. You know what receptor agonists do? Agonist and antagonists… they block or activate target receptors like anti-depressives etc.
There is such thing as receptor dysregulation due to these types of drugs. This happens because its the mechanism behind addiction. Your body has a feedback that will reduce or increase receptor volume depending on how much external or internal agonists or antagonists the receptors engage with.
So you might be losing weight but your receptor volumes/balance are 1000% getting damaged. Just like meth heads etc. thats all of you ozempic zombies.
I have Lupus and experience something called wasting disease, it causes dramatic changes in weight and the sicker I get the more compliments I get… it’s almost ridiculous at this point. “Girl you look great!” I’m like thanks it’s an illness 😂😂
Sorry to hear that! 😢 I have a milder autoimmune disease so I'm familiar with lupus. Neither it nor wasting disease sound like fun at all (to put it mildly). I hope we get some monoclonal antibody, other immunotherapy, or next gen probiotics treatments soon that effectively cure diseases like lupus, MS, RA, Sjogren's, Hashimoto's, etc.
There's already a lot of research into the microbiome suggesting that FMT can potentially put some autoimmune diseases into remission, but FMT has the psychologically gross angle to it (even if purified) plus it doesnt scale up as well as other treatments might.
Anyway, if you regularly see a rheumatologist, it's worth asking to see if they are monitoring that space, because out of genetics, environment/diet, and microbiome factors, only one so far has been very addressable, as conventional probiotics dont do much and gene therapy is still expensive and experimental for many conditions, beyond some promise of mRNA and other breakthroughs.
This happened to a friend of mine as well. "Wow, you look great!" "Thanks, I can only afford ramen and rice"
So sorry. This is exactly why I think no one should ever comment on someone else's weight. There may be health reasons, medication changes like chemotherapy, and mental health issues causing weight gain or weight loss.
@@CinnastixChickI think giving someone a compliment is totally fine even if you don’t know their backstory. Obviously any rude and disrespectful opinions should always be kept to oneself though.
I lost 30 pounds in 3 weeks with mono and people were like, "You look great" and I was like, "Thanks, I was nearly hospitalized because I couldn't swallow."
I have been on tirzepatide for about a year now for type 2, but I went from 215 to 155 in about a year. It had some side effects yes, but I also have great labs now, and I am no longer diabetic. Doesn't work for everyone, but it has changed my life and the biggest thing people are not talking about is how much I have saved on food cost over the last year.
Diabetes is perfectly treatable with a healthy diet. My parent did it. Ozempic is just another dangerous health-for-profit drug.
What would happen if you stopped using it
The snack food industry is going to lobby against these drugs.
Let them. It won't stop people from realizing the cost of living is cheaper than snacking. This goes beyond some vanity reason to look better. This genuinely curbs potential for heart disease and heart attack in many patients and that benefit alone cannot be emphasized enough.@@Hypnotoad582
@@Worldaffairslover Great question, my guess is I would slowly pack it all back on, I gained all my weight a few pounds a year over years, I snacked at night and drank lots of beer, the meds have made me snack less at night and drink much much less beer. Old habits die hard, I am on a lower does now. Since I have the diabetic diagnosis, as far as I know I will be on it forever. I also take metformin daily.
It was therapeutic to just see a 20-minute video full of factual information and some reasonable discussion about it. Thanks.
What I loved the most on ozempic is not even the weight loss is this sense of FREEDOM from food addiction. That I can start my day not feeling like food has an importance. That I can focus my energy on something else than food and the pleasure it brings. This satiety feeling is priceless, the feeling to be full is just really confortable. It made an end to this eternal emptiness and desire to eat snack that I had before. I didn't had to worry about calories , macros.... no nothing, my body was in a state where it can regulated himself without me having to "self control " my hunger, to work on felling satiety ( I was never able to feel it). For the first time I felt like everyone else: Eating a meal , feeling satiety up to the next meal. Then losing weight become easy without those craving !
Lies again? Olympic Medals Mee Goreng
You take something very important from your body too. It is called hunger. As shown, loss of the feeling of hunger dampens your general activity over longer time spans. Not a smart idea!
@@dr.paulwilliam7447 Hunger was there , manifesting gently, slowly building,. The medicine is actually not cutting hunger at all but it works with the satiety hormones, it's not the same thing. Feeling full after a meal is what was different from before.
@ hunger and satiety are different things. Hunger was still there. I’m only speaking about the long satiety feeling after a meal.
@@mariec3414 Are you still eating the same foods or did you improve your diet?
That last remark was really powerful: "it might just be a band-aid, but sometimes all you need is a band-aid."
It's degrading. Lmfao. Big pharma just lost their biggest supporters.... expect more of this
❤
Marketing ploy...........in the end this still became a commercial for Novo Nordisk, and an excuse to pacify and enable the lazies and lack of self control in scamerica.
💊💊💊💊💊💊 over vegetables and exercise
@mankind8088 yup
@@mankind8088exercise and diet may not lead to weight loss, but they will definitely make you happy and healthy.
The psychological / "food noise" benefits of these drugs are magical for people that suffer from them.
The so called "food noise" is the body responding to a lack of nutritious food. It is screaming for nutrients and fiber. We interpret this as food cravings but the cravings are never satisfied because the food lacks the nutrients the body needs. That is why you see people eat a 3 course meal and still feel hungry 30 minutes later. A lot of folks sabotage their diets with high glycemic foods.
@@megeek727 idk if it's fair or realistic to sum it up so simplistically. As someone who has, at times, had an extremely nutritious diet with very limited carbs and high intake of healthy proteins and fats and fiber, and at other times in my life, had a much shittier diet, the food noise has just always been there. As a constant. We're talking like a voice in my head going *snack snack snack snack get a snack go get a snack when was the last time I ate oh man I really want a sweet and salty snack I need it I need it*
All the time, regardless of how "good" I was being at a given time about my overall diet. And that's why all my good, healthy dieting eras never lasted permanently, because of the overwhelming food noise.
But in the last 4 months with Zepbound, it's just.... so much quieter. I wouldn't say my internal monologue about snacks is COMPLETELY gone, but I find that I'm able to redirect my attention pretty easily now, in a way I just couldn't manage to before. It's now more like *hmm I haven't had a snack in a while, maybe I should get a snack? Eh, I don't think I need it. I'll just play with my dog.*
So I'm pretty inclined to disagree with your suggestion that the food noise phenomenon from GLP-1 drugs could just be replaced with better nutrients and fiber. Especially when obese people have been trying the "just eat better" approach for decades with a 95% overall failure record. In fact, the whole conclusion of this video supports the idea that we should all be avoiding the impulse to overly simplify anything when it comes to obesity, nutrition, and fitness.
Similar to how methadone reduces cravings for heroine in addicts. You replace one poison for another
I hate to break it to you, but 100% of people have "food noise".
"Food noise" might be apt and real, but it needs as much skepticism as the "chemical imbalance in the brain" marketing that was used for some medications in the past that had little or no supporting evidence. It might be a useful phrase to describe an addiction, but beware the stealth marketing angle that uses it as a talking point or amplifies that PR messaging.
Anything that potentially works that broadly should be as much cause for concern and monitoring, not just seen as a panacea for addiction.
I have a PhD in Genetics and TH-cam is not the place to teach genetics to people. BUT, I just want to take 1 minute to explain a basic concept. Next time you are in public, look at people around you. We all look different, you agree? What you have to understand is that it doesn't stop with the outside, it is exactly the same with our cells. We are all different. Even children from the same parents are not clones of each other (even twins). So how can you believe that any given drug (or technique or whatever) is going to work the same for you body and for the person next to you?
How can I give 10 thumbs up to this remark!!
Agreed. There are scientific studies showing that some people respond to GLP-1 drugs and some don't.
Your comment highlights the insanity that is the social pressure for everyone to have the same figure of a pro athlete and 1% body fat.
@@TimelyAbyss Or, when we have Covid-19 (and I apologize for the BS that was said in the news), it is why you have people who are sensitive to the virus (and will die because we don't have the technology, yet, to save them) and others that are resistants... It is the same pattern with all bug, just the percentage of sensitives/resistants change (of course there are some people in between that we could save - and, also, it is a dynamic equilibrium - etc.).
@@megeek727 Any drug work differently for any single individual... Worse, the recommended dose for drugs is not always adapated to all individual and can sometimes present severe risks (yes, paracetamol, I am talking about you).
6:20 it might be a big win for big pharma but it's an L for the junk food industry. I save so much money on food now and I only have a $50 co-pay. Since I eat less, my body is constantly demanding healthier foods to keep me going. The only time I'm eating junk food is when theres literally no other option.
(I’m not being critical and see the benefits of the drug. I’m very pragmatic.)
Generally, if people get committed to exercising and getting healthier, it trains your taste buds over time. And, a mental mindset.
@@HKim0072 I argue it doesn’t train your taste buds, rather with increased good food intake the body adjusts to higher efficiency energy sources which causes the dopamine response to processed sugars to decrease which is perceived internally as the body preferring nutrient dense food sources (or in my case demanding high protein & fat, aka ketones, causing me to feel sick when blood sugar spikes instead of ketones)…
Not on ozempic but made the switch naturally.
You should have to pay the whole thing. You got fat on your own, lose it on your own. Glad I pay my premiums to cure your bad decisions
Also, it might very well be a net loss for the pharma industry long-term
@@HKim0072 Exercise trains your taste buds?
The US farma is a scam. In Greece my Ozempic costs 10 euro (basically 10 USD) a month with prescription or 100 without
Another take us US is subsidizing pharmaceutical research and only other countries benefit
The U.S. arm of pharmaceutical companies, pay for research and development (R&D) of new drugs, hence the “justification” that we in the United States pay more, which is BS. Consider yourself lucky that you live in a country where GLP1’s are affordable.
@@Werdna12345 Ah yes Denmark, the 51st US state.
@@mathieuroy6572 perfectly said. No no it’s the foreign countries who make American healthcare bad! 😂
@@mathieuroy6572 Didn't you know? :D
The trouble is that when selling us bandaids makes rich people money. But solving the systemic problems causing the illnesses would lose rich people money. We’re probably never going to get past the bandaid
The video was a bit deceptive in regards to losing muscle mass. These drugs cause a decrease in muscle mass and bone density. You will notice that the video mentions losing something around 4% of your bodymass on these drugs. Notice that it never says how much actual body fat you lose.
I have rheumatoid arthritis, when I stopped wegovy, the symptoms got so bad (despite not changing my healthy diet) that my doctors gave me very bad news. Three different drugs to stop the rheumatoid arthritis, nothing is working. I’m back on Wegovy, now my symptoms are calming down again. I don’t know why. We don’t know why.
Funny I have Fibro and Athritis - wegovy did the same to ke. I felt great! More energy less pain. got off, all the pain.
we don't know why.
That's fascinating. I am going to pass this on to my mom. I wonder if it would help her.
@ Hey! Yeah no. I did fasting for years and no, it does not work. Prayer also does not work. You’re talking to someone raised very conservative with parents who mentioned exactly that. Don’t you think I would’ve done all of that before paying $1500+ per month before my insurance kicked in lol.
@texasgermancowgirl forgive your parents because they made mistakes. Please. Prayer does not show if you can not see it. It is there. You are fasting when you take the medication, there is an allergy that is attacking your cells. Foods are compounds broken down in our digestive tract. You are fasting. If it is helpful but hard to get then God is helping but there is opposition. Your parents tried ma'am. They cared. Take God out of the box they put him in and find who is he for yourself.
@texasgermancowgirl i apologize for the pain you have. You don't have to laugh. You are allowed to cry. It is hard.
I was ready for a fight in the comment section seeing the thumbnail. I was pleasantly surprised to find a quite reasonable discussion and insightful questioning into the topic. Thanks for an informative investigation and rational take.
This was an advertisement for Ozempic, pure and simple. The cost to produce it is less than $1.00 per dose and the pharmaceutical companies are bankruptcy health care plans.
I started tirzepitide about 3 months ago and feel so much better. More energy, less food obsession, more clear-headed... etc
I used my savings to be on ozempic for 3 months. I lost 15 lbs but the food noise being quiet changed my life. For once I was like ‘damn, this is how normal people live without being controlled by food?!’ but I couldn’t afford it. $400 a month out of pocket. I wish so strongly it was more affordable.
Since there’s a shortage there’s online pharmacy’s that sell it for $175-$200 a month. Try hims/hers or just Reddit
Therapy and lifestyle changes will be cheaper in the long run
Trym health is a compounding pharmacy that offers 3-4months of the medication for about $450 in total. That’s where I got mine. It’s as legit medication. I’ve been on it for about 3 months down almost 20lbs
Eventually there will be a generic.
buy it from china...like i did.
Ive been on it for almost 2 years. Ive only lost about 35 lbs. But my stomach fat is melting away. I do walk and workout also. This has been a great option for me to get my blood sugar in check. My A1C is better than it has been in years. A bonus is that I no longer want alcohol and save a lot of money on groceries and chasing food cravings. To do this day, I cannot kick the ice cream habit though.😊 Since I need this drug, I pay nothing for it. Its 100% covered by insurance.
What makes you “need” this drug? Are you obese?
Check out frozen yogurt ice cream or a ninja creami to make your own low cal at home
Hurry up! When something is covered by insurance, everyone else is paying for the cost. It's definitely not "free".
(half joking / half serious)
@@HKim0072 😂
@@Extrafancytoaster Thanks. I'll check it out.
What a lot of people don't talk about is that in the studies, up to 40% of the weight loss is muscle mass. Then the weight that is regained is usually adipose tissue (fat) which leads to a condition usually only seen in older people - sarcopenia. Your overall body composition is far worse off and I fear this will lead to an epidemic of osteoporosis, fractures and frailty. Time will tell.
This is a great point that was overlooked in this video
But the muscle mass loss isn't any more dire than in any fast weight loss, a person would get the same result with losing weight with bariatric surgery or fasting. So your point isn't relevant for the video.
@@Emmuzka Incorrect. With a decreased caloric intake the muscle mass loss was due to lack of physical activity which wouldn't be the case with someone who loses weight with proper diet AND exercise. Also, the average loss of lean muscle mass after bariatric surgery is approximately 12 percent, which is significantly lower. Less muscle mass leads to a lower resting metabolic rate. As a physician who actively practices and discusses these issues with patients I can assure you I know the data very well. To that point, intermittent fasting was shown to increase the risk of cardiovascular death by 91% so that's another area of considerable research currently.
I have had barely any muscle loss losing over 30 pounds. It depends on how it is done, not a guarantee.
@@SinisterMD Interesting. Can you link me a study where the significant difference of 15% from bariatric surgery and 40% from GLP-1 mediacation can be seen?
As someone that naturally lost 180 lbs in the past 2 years, I only heard about Ozempic last year. I had a friend start taking it and she lost an average of 8-10lbs per month, at the time the same rate I was loosing. So we had a super open Conversation about what she ate and literally everything she ate calorically was the same as much as me. The difference is while I was eating and The difference is while I was eating in a calorie deficit and high-protein. She just at less. Less volume food. and was eating Half the amount she usually ate. While my diet was calorie deficient and high volume food I was still very hungry throughout my diet. and still am to this day. This medication basically takes into account willpower it makes it easier because it helps you not feel as hungry.
They mention in this video that there's a worry about losing muscle on Ozempic, but it was a little bit brushed aside talking about how if you lose weight through diet and exercise you'll lose some lean muscle mass. I've seen a dietician talk with somebody on Ozempic about their diet, and she was saying the person on Ozempic needed to up their protein to maintain that muscle, because muscle is good for you. If somebody is just eating less of everything, and not looking at what nutrients they're taking in, I can see this having a much greater negative effect on muscle than if they do what you did, which is something I would worry about.
I've worked really hard in the past few years to put on muscle, to help with my arthritis and my long term health - I wouldn't want to lose weight but sacrifice that muscle, because that feels ultimately worse for me in the long run than not losing weight but having more muscle than I did before I started strength training, especially if you regain a lot of the weight after taking Ozempic.
@ like 4-5 month into I started I’m eating 1g of protein per pound of my goal weight. Ya super important everyone needs to that if they are on these drugs. It should be the most important part of the diet
@@ChantelleHale I am on Monjaro and I am generally maintaining muscle. It is effectively impossible to lose significant weight and not also lose some muscle, however, my primary form of exercise for years has been weight lifting and I am simply continuing to do that. Most people who go on any calorie deficit eating plan should monitor protien and add some form of resistance training.
@@ChantelleHalecertain muscles are simply less necessary if you are lighter. If you’re obese you need good strength or you will have major back issues etc. Being obese is like permanent, enforced weight training. So all else equal, you will lose muscle when you lose a lot of weight because you’re training it less. You can offset this by increasing your weight training.
People, stop accusing others of "cheating" weight loss by using Ozempic. First, you could be dead wrong, and the person might be losing weight because of chemo, an illness, or something else. Second, they should not feel obligated to explain how or why they lost weight to you. In fact, let me make this real simple: just don't comment on other people's weight.
You're right however it's a valid question when influencers push their diet teas and workouts but actually take a weight loss drug to get their results.
actaully your weight is everyones buisness because it effects society on a massive scale. it doesnt just effect the obese person or malnourshed person but everyone around them too.
It is cheating though when you compare it to those who lost weight doing the hard work. Sorry but it is
@CinnastixChick AND, here you are, "commentating" on other people's weight through their own comments. Ohhh, the irony!
@VladaldTrumptin Gatekeeping health is so bizarre. I went from 250lb to my ideal weight of 160 with diet and I don't have a problem with people using Ozempic to do it because why the hell would I?
People cry about how unhealthy it is to be fat and that people need to lose weight. Then when people lose weight suddenly it's not about the health, its about not losing weight 'correctly.'
People just love putting people down in any way they can. It's just a shift in bullying. 'Oh we can't bully you for being fat anymore but we can invalidate your accomplishment and make you feel worthless some other way.' It's pathetic.
Ozempic saved my life. I had diabetes and a genetic cholesterol of 300. Both are gone. I’ve been on it for two years. I was 140 pounds and ate low fat, low sugar. I had a heart attack at age 50. Statistically I had an 80% chance of dying after one heart attack. Six years later I am still here and healthy. 130 pounds, cholesterol of 100, and excellent glucose levels. Starting Ozempic was the only change.
the endocrinologist i saw to discuss taking ozempic was very candid and pointed out that ozempic might be dangerous for patients with depression: he said some of his patients who had depression reported that being on the drug heightened their suicidal tendencies which made me decide that i didn't want to roll the dice to try this drug.
This is super interesting. I wonder if there's a chemical reason or if it's as simple as food being a source of joy and taking it away can make those who already struggle with depression even more miserable. One of my friends who struggles with depression went on an ozempic type medication to lose some weight and it made her feel full constantly, to the point where even though she knew she hadn't eaten in a long time, the thought of having 1 bite of anything made her nauseous. She was on it for 3 weeks before she decided it wasn't worth it. She's also one of those girls who's 10-15 lb.s overweight and thinks she's humungous so she didn't have much weight to lose anyway haha, not sure if that has something to do with it too
I’ve heard this, but from the perspective of since the drug makes people ignore hunger cues, it makes depressed people who already struggle to eat or eat healthy more likely to just not eat at all and starve themselves, which I guess technically is a suicidal ideation…
I've also heard this. On the flip side, I've heard that with some people it helps with depression. Speaking firsthand when I started taking Mounjaro for Type 2 (tirzepatide, not semaglutide), my chronic depression eased and my "normal" mood was more neutral than depressed. I'd previously tried antidepressants and cannabis. Neither option helped me and both had unpleasant side effects. On Mounjaro, it was easier to find happiness in things besides food (and I even developed a disinterest in food. Food has been my drug of choice for over 20 years and just like that I had lost interest in it.) I was so surprised how Mounjaro helped my depression even before I had lost any weight... I didn't expect that.
@@garou12 as someone with depression who’s currently on zepbound, I will say, the first couple months were extremely tough. I’ve always used food and alcohol to push through those severe depressive episodes, and when I got on the drug, food did NOT help. It was always a coping mechanism for me, and I remember being EXTREMELY angry that food no longer brought me any kind of joy. Thankfully my family was there to help me through it, and so far, it looks like I’m on the other side of that problem (at least, for now), but it was scary for a few months there. The plus side is, now I have healthier coping mechanisms, but getting to that point did, admittedly, feel dangerous. It’s also been extremely helpful in reducing, and nearly eliminating my dependence on alcohol.
I’m glad your doctor warned you about that potential. Mine did not, he just said I wouldn’t want food, and made no mention of WHY I wouldn’t want food.
@@sahjeii The gut produces the majority of your serotonin. Ozempic slows down gut function, likely also slowing down serotonin production.
I got an Arby's commercial at the end of the video. One of the many additional problems Elizabeth McCauley briefly touched on in this video. Great reporting McCauley!
More videos with Elizabeth please. She's great.
What kind of videos... 🧐
The speed at which you speak is absolutely perfect. I normally have to put videos on 1.5 but yours was great pacing! Lovely
If you've trained your brain to expect that speed, that's possibly setting you up to be impatient and rude to people in the real world who talk more normally. It's (ironically, given the subject of the video) a bit like wolfing down fast food rather than just appreciating a meal.
@@zivzulanderI listen to everything on 2x. Americans typically speak really slowly so speeding it up makes it bearable.
I started Ozempic about 6 months ago to lower my blood sugars, as they were about double what they should be. It lowered them to normal within the first month and has remained the same since. I did lose over 30 lbs. as well, but that was not as important as the blood sugars. I still lose at least a lb. a month, but I eat the same as before I started the Ozempic. I am not on any type of diet and eat whatever I want. My sugars are still good and I am slowly losing weight. This is all that I care about. If the only reason you are on it is to lose weight, you will fail. It seems to me the initial weight loss is due to the reduced amount of sugar to you cells. Once your body adjusts to the new level, the weight loss will slow to a crawl. If I did cut out sugar and carbs, the weight would start to drop drastically. I am old and want to enjoy my remaining years by eating anything I want instead of dieting. It took me 15 years to put on the excess weight, so I am expecting it to take that long to lose it. No worries, no stress, no dieting, that is what I am doing to enjoy my life. Lower your expectations and you will succeed.
"but I eat the same as before"
no you don't, you just feel like you do
*12:20** You are so right about the punishment. People WANT to believe that those who succesfully lost weight will experience these dreadful side effects because they hate the idea of weightloss being a bit easier*
Only in America, is health care and prescription drugs such a rip-off. In most other countries in the world, pharmaceuticals are pretty affordable.
Because American subsidize the lower cost in the rest of the world. If america had govt regulated pharma pricing... All pharma prices would go up globally.
You really think AIDS meds in africa cost only $1? They give the drugs away to poor nations at a loss, because they recoup it in the US @ $1200 per pill.
Not far fetched that a company like business insider has its own vested interests and affiliations
Treating the symptoms of food addiction but not fixing the root problem. It's a big win for processed foods and big pharma.
I take it for weight loss. It is not an “easy way out”, it is a game changer. Feels like a miracle. The side effects hit hard, but I had them only for two weeks (max dose, no ramp-up).
Important anecdotal details I have not seen covered:
1. It does not work the same way for different foods. For example, I am physically unable to drink an entire cup (sometimes half) of coffee now, but pizza? I could just keep going. Of course, I don’t because it would make me throw up the next day, but the medicine doesn’t help. Most likely this is different for different people.
2. It helps a lot with self control, but also requires a different form of self control. Sometimes, I have to remind myself to eat when not hungry, because if I go too long, it triggers side effects. Other times, especially the day before a dose, I no longer feel the effects so I have to control myself or suffer the side effects 2 days later.
The will power part really helped me, the amput of food i have rejected with no remorse afterwards, also my choices regarding food, since i know i will be full after eating a bit, in choose to est more nutrition densed foods
I simply want to say that the host Elizabeth McCauley presents extremely well and clearly, and the subject feels like it was analyzed in depth. An "S-tier" host, as the kids would say.
I’ve lost 175 pounds (40% body weight) on Zepbound and eating low carb over 2 years.
I’ve dieted my whole life and never had these results. These drugs ARE a miracle for many people!
The same results can be achieved through diet and exercise. If the drugs are staving off your cravings then as soon as you stop taking the drugs then youre likely to regain the weight unless youve done the work to curb your cravings yourself. So these drugs are only a temporary treatment to what are behavioral issues. They shouldnt be used by people without a specific reason to do so. Weight loss isnt a good reason to use them.
@@supernova743
At most it is only a temporary fix if you stop taking it
I lost over 100 pounds without it, but I was put on it for type 2 diabetes. Losing weight is definitely easier with it. I don’t think about food constantly like I did before. So before I had to have huge willpower to lose. Now it’s just a thing. It’s dropping off without trying.
@@supernova743 This is simply inaccurate for a huge swath of the population. You'll find countless examples in this comment section, myself included among them, of people who've used diet and exercise to lose more than 100lbs, and at no point in that journey do you ever lose the cravings for food, whether nutritious whole foods or processed junk food.
I'd cut processed food out of my life years ago, and I STILL gained weight, because I'd sit down to a bowl of curry and rice, and have seconds, and thirds. The most processed thing in that meal was the flour and the white rice. My body/mind found joy in eating. It could be a whole chicken i roasted myself, or a steak, or mashed potatoes made from scratch, all of it brought me joy. When I lost the weight naturally, the cravings for those foods still existed, even white rice, chicken, and broccoli would make me happy to the point where i could consume so much of my "healthy foods" I'd still gain weight.
On zepbound, it doesn't just "stop your cravings" it changes how your mind/body regard food. For many people, food releases dopamine. Again, not just junk food. I'd be elated eating plain chicken and rice, to the point where i could consume pounds of both in a sitting. Now, I can take a bite of my favorite foods, curry, steak, sushi, whatever, and feel...nothing. The first few months on these drugs is often frustrating for people because they've spent their whole lives finding happiness at the end of a fork. It's often the most reliable dopamine release people have, and from literally day one (in my case), it vanishes over night.
I've become more social with both friends and family as a result, because now that food doesn't make me happy, I HAVE to find that dopamine release somewhere else, and that somewhere else is a much healthier place. I spend more time hanging out with my friends, or spending time with my family, because I have to. I don't have any other sources of dopamine. Food just stops being a source of happiness, and because that's the case, you not only stop eating junk food, you also, often, stop drinking, and you also eat significantly less of even your healthy meals. Now I can sit down to a bowl of curry, eat a single serving, and walk away without a second though. I've been able to FORCE myself to make that choice, but now, my body WANTS to make that choice.
That simple difference is liberating, and if it's not a struggle you or someone you love have ever been forced to endure, it's really difficult to find empathy for those going through it. The facts are that, while you're on the drug, you develop a non-destructive relationship with food. You know you need to eat, and you do still, but you don't have a desire to snack, you don't have a desire to overindulge, and you no longer find happiness in food.
So yes, you can, and I have, seen similar results with willpower and exercise. The difference is, every day is a mental battle. It NEVER gets easier, and you ALWAYS lose eventually. It may, and in my case, did, take years to take that L, but it does happen, because the entire time, food was always sitting there as an easy out in a stressful situation. It was just election season, a really stressful time for a lot of people, and for me, and at no point, did food EVER seem like it would ease that stress, and that was liberating for me. I expect I'll be on this drug for life, just like I expect to be on anti-depressants for life, and previously expected, and still may, to be on statins for the rest of my life.
I'll probably see the same physical results that I've seen many times in the past, where I get down to a healthy weight (I've been as low a 165lbs at 6' tall with 0 drugs), but this time feels different. I don't have to argue with myself about portion control or whether I should go down the chip aisle at the grocery store. I don't have a desire to over eat, and I don't have a desire for snacks, and it's the first time in my 20 years of being an adult that I can say that.
@@supernova743are you really trying to say that someone who used to weigh 425 pounds shouldn’t use whatever tools necessary to loose weight? You are a fool and clearly have no idea what it is like to struggle to loose weight. My results have been achieved with GLP1 *AND* diet and exercise.
On 11 June 2024. I was 101kg and started mounjaro, changed my eating habits and started exercise daily. I reached 72kg on the October stoped it, I kept exercising and eating less and I didn’t put any weight yet. I really happy and feeling a new person
You're not just being lied to about Ozempic. You're being lied to about nutrition in general. The average North American still thinks fat makes you fat and eating cholesterol causes high cholesterol.
This+ the prices of processed foods compared to Whole Foods like fruit and veg… I’m American and lived in Japan half a year and while my diet in terms of foods/amounts didn’t change much, just the amount of more Whole Foods and less processed junk really made a difference. Came back to the U.S. and my stomach was not happy ://
Hopefully RFK will help fix this. I think we're going to find scary things about seed oils, dyes, and herbicides & pesticides
Bruuh is this peer reviewed/meta analysis? Stop the cap
They best way to prevent these diseases is to eat right. We are in the era where our food are grown with fertilisers, sprayed with insecticides and are no naturally grown. Water to drink are not safe for consumption, we breathing in toxic air. The solution is to eat right.
Eating too much cholesterol does cause high cholesterol... No one is lying to you regarding this. Just because you changed ur understanding of things doesn't mean the world perceived things the way you did before you fixed ur misunderstanding. Stop projecting ur ignorance.
This vid is weirdly very skeptical of negatives, and extremely permissive of completely anecdotal positives that have zero evidence behind them. It is not well balanced at all, and towards the end it becomes clear this is a sponsored piece. Disappointing this was not said up front.
I have to agree. It wants to appear balanced but just sort of brushes off the negatives. For example, it starts off with the, admittedly false, "No" studies for non-diabetic weight loss claim and just says "Well actually there have been studies" and then moves on. Ok, but how long have these studies gone on? Everything that I can find dates only to 2016 (for wegovy studies, with wegovy being approved in 2017). That IS very new. Lots of drugs get approved for a particular use, and then the true impact of side effects only becomes known over 10, over 20, etc years later. We're just coming up on the first 10 n year mark. The non diabetics being given this over the last 7/8 years ARE the test group for the long term effects. Will long term effects on non-diabetics being miniscule or harrowing? I don't know yet. Maybe there's no big worry. But this video just sort of mentioned "yes there have been studies" to discredit the exaggeration of "no studies" but doesn't admit the lack of Long Term study data. Kicking off with that makes me very skeptical of them treating both sides objectively.
Yeah 100% shocking biased presentation of data
"They were restricting their calories. They were following diet. They were exercising and it just didn't work." Congratulations, someone just found perpetual motion.
Remember that the body is complex. When you eat less, your metabolism can drop to lower levels. It's not "perpetual motion" it's "we don't know all the inputs yet to this problem."
@@jreese8284 I fully agree, body is complex but do not try to make this a problem with impossible solution. Yes, there can be huge differences in calories consumption per day. Two persons with the same age, weight, sex, can consume between 1500 - 5000 calories per day. Yes, when you lose weight, your body uses less, but at this point you have already lost weight. So it's time to rebalanced tour diet.
What would happened if this person who "can not" loose weight would have strictly controlled diet, for the sake of the conversation let's say in prison. And if this person can not loose weight in a month, it's time to reduce the calories. There is no way this can not work.
Ozempic does the same thing. It's lowering your appetite. You eat less > consume less calories > your body is loosing weight.
The real issue that isnt delved in too much is the fact that these drugs are not new. and yet they are sold in the US at incredibly high prices (at least when it comes to list price). Americans need clarity on pricing. I doubt insurance companies are paying over a thousand bucks a month. but those without insurance need to, and these are the people who may tempted to go to shady online pharmacies
In America you can’t have “freedom” without allowing huge companies to overcharge customers, duh. Freedom isn’t free, it costs 100x as much as it does in Europe bc you gotta please those shareholders!
It makes sense that people stop taking it after a year. No insurance covers it and the manufacturer coupon only lasts for a year. It’s not because people don’t WANT to be on it.
Where do you get no insurance covers it? Untrue.
One thing I noticed about most of the people who advocate against semiglutide have never been fat or addicted to food. I said SOME not all. I’ve been overweight all my life and recently became obese. This is the highest my weight has ever been. I believe I do use food to cope. Not only that my genetics. Diabetes and heart disease and obesit, even cancer is pretty much my whole family. I’ve lost many to these diseases. This is my fear which is why I took the step and was prescribed wegovy by my doctor. However, in order to keep receiving this medication I have to keep appointments with a nutritionist and a fitness instructor. I’m blessed because my tribe provides all of that at no cost to me. So far I have lost 20lbs so I would say this drug is working. It’s easy for me to say no to unhealthy foods I used to love. Sometimes even thinking of it makes me sick. This is journey I’m willing to stay on for as long as I can.
Very true. They don't understand the struggle
Not eating processed food was what helped me. Lost forty pounds in like three months. Also picked up marathon running. So. That helped.
Same. There’s two major problems with processed food that contribute to weight gain: the body burns through them too fast, causing you to feel hungry again, and they don’t have a lot of the micro nutrients that you needs in addition the calories, requiring you to consume more to make up for the deficit.
@@AWriterWandering
Another thing is that many ultra-processed foods contain sugar, a natural addictive drug. Sugar increases insulin and hunger, which causes you to want to eat more, and is a big contributor to obesity. Check the label next time you're at the store, and you'll be surprised by just how much sugar is in almost every food.
@@Persistence_run_444 I’m sure that avoiding processed food was beneficial, but if you were already at a weight where you could “pick up marathon running” you were no where near the size that you would have any business being on one of these drugs, regardless of how much weight you lost. So, your comparison is moot. Weight loss for a person in an obese/morbidly obese body has already gone through hormonal dysregulation.
@@BoringTroublemakerThe op did state that he/he lost 40 lb. That's not somebody who didn't need to lose weight
@ a person who is 20lbs overweight can lose 40lbs. Just because someone lost 40lbs doesn’t mean they HAD to lose 40lbs or were even 40lbs overweight
I went on to lose weight so I could qualify for a breast reduction (I live in a place that is only now getting rid of BMI requirements). Now I’ve had that surgery, and being able to be as active as I’ve always wanted to be and scaling down my shots because I’ve essentially lost my appetite and I’m not eating enough for my body to stay out of starvation mode.
after having been on medication that either increased my appetite, decreased my appetite or made me gain weight regardless of what i was eating, it's become so obvious that all these things truly can be out of our hands depending on how our body works at any given time.
people who have naturally lower appetite, or fast metabolism tend to think "well, if it's easy for me to maintain weight, it must mean you're just not trying hard enough" but that's so wrong. i hope we can finally move on from fat shaming and instead focus on understanding each individual's issue that's causing it so it can be addressed
You just have no self control
@@SF-eo6xf gj proving OC's point lol
@@SF-eo6xf there's also no such thing as a fast metabolism. a drug that makes people eat less causes them to lose weight. in other news, water makes things wet
"fast metabolism" 😂
ignore the dumb assholes, you're absolutely right. Several scientific studies have shown most weight loss people experience trough exercise and dieting comes back within a year. Weight loss isn't achievable for a lot of people, and additionally is frequently detrimental to people's health. Caloric deficits have been shown to lead to a plethora of health risks associated to stress on the body.
While I think the title of the video is a bit clickbait at the time, "You're Being Lied to About Ozempic", the video itself is really good I feel.
It goes over a lot of the potential misinformation seen online or in the news about all the dangers, while also taking about the actual dangers of the drug/compound version of the drug and as the fact that it's not a miracle drug and that it doesnt always work for everyone.
And talking about the bigger issue of weight lost and health too and how exercise and how complex it is, that also was good information to have in the video to complement the information about the drug.
It's always bad. People who think it's good long term are just grasping at straws to justify using it.
I swear the word misinformation was pretty much non existent before 2020. Now the word makes me cringe because it feels very NPC
Why is it when a device is invented that saves lives or makes life more comfortable noone has a problem with the manufacturer making money, but when a drug does the same it's seen as almost criminal?
I think it’s mainly because, as you said, these drugs save lives. And the problem is not companies making a profit, the problem is companies being “greedy” and gatekeeping the drugs/treatments in order to make larger profits.
Don’t get me wrong, I’m 100% pro-market lol.
But I do agree that sometimes, with stuff like this for example (drugs that can substantially improve the health and well being of hundreds of millions of people that have a medical condition like obesity), these companies (more like their owners/shareholders) have the moral obligation to make the drug accessible to as many people as possible.
I mean, they have already covered the cost of production and research SEVERAL times over, everyone at novo disk is already rich asf, generational wealth kinda rich.
Is it a bit unfair to them? (because they invested a lot of money into the research and development of something that could not work at all and fail)
Absolutely, it is unfair! Yet it did work, and they did get richer than they already were, and they can still keep making more money (just not the absurd amounts of money they are currently making)
That being said, there’s also many people who are just conspiracy theorists and are convinced “big pharma” is out to get them lol
Your brain is cooked, my friend.
It's not that they make money, it's that the cost is significantly more expensive in the US than it is worldwide since they can get away with it and thus prevents many people who may need it from affording it.
You are presenting it as a binary choice, either the drug companies make "no money" or "all the money". I suspect that they could lower prices substantially and still make significant and worthwhile profits.
If people could get it on copay I think people would be singing their praises and thrilled they were getting rich.
A lot of people can't, which is baffling.
5:16 for me it was harder to lose the weight. It’s been easier to keep it off. I lost 70 pounds on my own over six months. I weigh myself every day and adjust my diet accordingly.
Yep…this definitely sounds like an ad for Ozempic.
It's good I use it
it's always strange when people equate "not easy" with "doesn't work" with regards to losing weight. I think it should be made clear that for the people where lifestyle changes "doesn't work" that the juice, for them, wasn't worth the squeeze. No shame in that, but saying it "doesn't work" is wild af. That is a crazy level of a victim mentality.
You're stupid.
Go back, learn about rigor.
18:10. I call BS on what he says here..."They were restricting their calories"...and didn't lose weight. Were they really restricting their calories or did they SAY that they restricted their calories? There is a difference.
I was obese and not eating that many calories and not losing weight- but I then instead stopped eating sugar and stopped eating processed foods, and I lost 55 pounds in the past year without calorie counting at all. It can be more complicated than just calories. Eating low calories of processed crap did me no good.
I've been taking Trulicity, which is similar to Ozempic etc. for over a year now. I haven't lost any weight while taking the medication, but it has been really helpful in managing my Type 1 diabetes. Even though it is technically for Type 2 diabetics, it has helped to keep my blood sugar from spiking drastically after meals, and that has been great because large fluctuations in blood glucose can mess with my cognitive ability and make me feel sick, so it has definitely been worth it even though I haven't lost any weight on it.
(edited because I mistakenly wrote Tresiba instead of Trulicity)
Tresiba is insulin dear. Totally different mechanism of action than GLP1 agonists. Insulin may in fact cause weight gain. Do you mean trulicity? Anyway, cheers and happy losing!
Yeah, actually it is Trulicity, my bad. Good catch though
Destruction of physical labor in favor of desk jobs along with the rise of chemical riddled fast food has created the obesity "epidemic". Companies now want to capitalize on a problem they caused by forcing you to pay money to lose weight. Instead of, you know, improving the work place environment. Which they never will, because that would mean a decrease in perceived "productivity" and extracting every ounce of labor from employees is how companies operate. Let's also not get into how these transition from analog to digital has made people lazy to the point where they'd rather rely on drugs than make the effort to change their lifestyles. Because "effort" is too slow and people want instant results even if the results are harmful.
My biggest concerns are that it's replacing a hormone which has natural on/off cycles, and it's doing it by basically flooring the gas pedal. Let's hope that signal isn't a growth factor for cancer, or a trigger for some other dire medical issue.
And to that second bit, in some people, it slows down the gastric tract in a way that doesn't seem to stop when they stop taking it. That can be good, if the result is therapeutic. It's a disaster if it's too slow, and it seems to cause, what appears to be permanent, gastroparesis.
Additionally, the body composition of people losing weight from it appears to be 50/50 fat mass and lean tissue. This is equivalent to the body composition changes associated with starvation. Which means that basically it's just "regular old dieting" and if you stop taking it, and it's effects wear off... You're right back where you started.
It is. What happens to a system when you turn up the processors. It over heats. It stops being as efficient. It stops working.
"Let's hope that signal isn't a growth factor for cancer, or a trigger for some other dire medical issue."
For some of us in the super-obese category, it's a fair trade. I've dropped over 110 pounds in a year on tirzepatide. Without losing that much weight, I was very likely to die of some weight-related issue and quite young. Neither of my (obese) parents lived to see 65. If I get 20 years of far more active healthy living than I would have without and then some nasty cancer from the drug at 70 and die? Guess what, that's a total WIN, not a disaster.
@@MostlyHarmlessNebr-gb6di that's great, and I'm glad it's worked out. And I hope it continues to work out for you in all possible ways!
They are incredibly interesting drugs and can be helpful for lots of people, and they are also teaching us a lot about the biology of appetite/craving in ways we did not expect.
Thank you thank you thank you!!! Its been so hard to cut thru the noise and chaos to see any kind of truth about these drugs. Your reporting feels like the first time i have encountered something balanced and fairminded about the whole thing!
As a PCOS sufferer who had a baby in my late 30s, weight loss is next to impossible. Despite being a lifelong runner, a running addict, and eating right! So my doc prescribed ozempic and then tried for monjourno which is the one helping specifically PCOS women. No insurance would cover it despite saying they would and after a year i gave up hope, resigned to the slow slide into obesity and diabetes - typical outcomes for PCOS sufferers. Then came stories of stomach paralysis and family said its good you didnt get the meds, but i still feel unhealthy and ungainly, and even with the side effects i would try anything at this point to feel like a healthy approach is rewarded with my body losing weight and being more fit.
We'll see what happens. I still hope i can get the prescription someday, because we do not have $1,000 a month to pay out.
So as a guy who has psoriatic arthritis I can't really do enough exercise without doing harm to my own joints in excess of normal wear and tear.
Yet despite that, me and being pre-diabetic, and obese my insurance refuses to pay for any injections.
According to their own statements regarding coverage for semaglutide injections I have 3 different symptoms of issues that would qualify.
So I'm struggling with my insurance that I can't get rid of to get a thing that I could actually use to help me lose weight that diet can't (basically it becomes the "exercise" part).
It's completely frustrating to both me and my primary care doctor since nothing that's been used by either of us has changed a thing.
Can you not try low impact exercise like swimming?
Look at any photo of a group of Americans from 1950, and you'll see virtually no bigger/overweight people. Now the obesity rate is near 50% in some places. You cannot tell me that people are bigger now because of "gland issues", etc. What did change? People are less physically active, portions are bigger, far more people have cars, fast food is everywhere. There are numerous other factors, like food deserts, people having less time to cook due to having to work more, pollution, etc. So yes, it's complicated, but it's also not.
Weight loss is NOT easy. That's a fact. Anyone who says "just do XYZ" is wrong. That said, people tend to ascribe nothing to themselves. It isn't "I shouldn't eat 8 cookies a day", it's "no matter how many cookies I eat, I won't lose weight" which simply isn't true. I'm currently "carb cycling" to lose weight. On Mon/Wed/Fri I eat very few carbs. It SUCKS, but it is working, slowly. I don't think it's unfair to expect people to actually try actually difficult non-drug methods for an actually significant amount of time. But I've heard people say "sure, I eat a lot of sugar and I don't like veggies, but I just can't lose weight". You don't know you can't lose weight because, if you're eating lots of sugar every day, you haven't actually tried losing weight. You do not get to eat half a box of cookies a day and lose weight, that's not how it works. Now, if you've tried all of the methods, done the hard things, your diet is actually good, and you still can't lose weight, then by all means, try this drug. But the fact that one is essentially committing to be on it forever should by itself be a deterrent to saying "I tried a diet for two months and it didn't work so I'm taking this drug".
Fully agree, I highly suspect the vast majority of people are not telling their doctors or anyone the truth, that they simply aren't trying, I see it daily in my own home and in my community regularly. People just don't want to do the hard work.
If you have yo-yo'd several times, you can get to a point where your weight loss will be minimal despite all efforts. When you gain weight, you gain fat cells. When you lose weight, your fat cells shrink but remain. More fat cells = more hormones to ensure your body holds onto fat. I went through many cycles of this before I learned it, dropping weight and gaining it back, getting heavier each time. Now, even losing 20lbs is an exhausting battle (though I am sure getting older has not helped either).
I go out of my way to warn people about this to make sure they don't get themselves stuck in the cycle. If you drop the weight, you better make sure you keep it off.
Wish I would have known that in my early 20's when I got relatively fit and lean after being moderately heavy.
@@masaharumorimoto4761physicians are highly trained in many areas, but most have shockingly very little training (what amounts to a course or few courses at most) on diet and nutrition, unless they take it upon themselves to do continuing education in that area.
Modern medicine is geared around treating chronic conditions with medications, and less so about strong interventions in diet or lifestyle. Not their fault, and we collectively as a society need to reform that approach on many levels.
@@Twosocks42, yes. But also the fear of yo-yoing is real. Yet another weight loss effort, from fads OR doctors, ultimately leads to increased weight, so it’s scary to even contemplate trying something else.
This video is one giant ad for Ozempic.
GLP-1 has beena popular "peptide" in the body building community for quite some time
Ive been on wegovy for 2 months and i lost 20lbs
I've been on wegovy for 6 weeks now and the biggest change has been how not eating affects my body. It used to be that if I went more than 4-5 hours without eating that I became shaky (to the point of having hands tremors) and hangry (irritable, snappish, etc) Now the worst I tend to get even when I have to go 8-9 hours between meals* is a mild queasiness. It's allowed me to eat smaller meals (that don't make me uncomfortably full, as was my previous norm) because I don't have to worry about having to tide myself over for as long as possible to prevent The Hanger from taking over lol
*I'm not purposely going that long between meals but I'm a fulltime caretaker to multiple disabled relative & sometimes between playing chauffeur to all their appointments and making sure they get their meals, I have to delay my own eating.
"This un-biased video is brought to you by Novo Nordisk"
In 1986, I took a contract in Saudi Arabia. I lived in the Mojave Desert, so the climate was pretty much the same. When I went to Saudi Arabia, I worked pretty much the same and ate pretty much the same. I weighed 230 lbs. In the second 30 days, my weight started dropping at a rate of about 2 lbs per day. My employer was so worried, they sent me to a doctor, who promptly started testing me for cancer. Fortunately, no cancer was found. I ended up stabilizing at 165 lbs. When I returned to the US, my weight promptly went up to 230 lbs again. The only thing different I could identify was that the food in Saudi Arabia was locally procured. I am convinced that a great deal of the obesity in the US is the food additives.
where there is money, there is advancement. i am curious where this all goes.
True, so many other groundbreaking meds have come out in the past few years yet Ozempic gets all the attention
Advancement only happens when there's competition, not money.
Not necessarily.
It might just make some rich people even richer which is the first priority. Advancement comes in behind that
I lost 225 lbs the "old fashioned" way, kept it off for a decade now, and I feel like trying ozempic to make the maintenance easier. Very true statement that losing the weight is the easy part.
I used cardio, weight lifting and diet to lose 25-30 lbs in 1,5 - 2 year's.
Lost weight and gained muscle, no hormone medication needed, just dedication and a goal.
Just a little more lbs of fat to lose.
I'd like to add that as someone riddled with a slew of chronic illnesses, I became desperate enough to start this about 5-6 months ago. I hoped that if I lost weight I'd get better treatment from doctors, and it would be easier to get further surgery for my dercums disease. The best side effect is my IBS is gone! I had constant daily diarrhea for two years, after five years of having it frequently. Since I'm actually absorbing nutrients and staying hydrated I feel so much better. The downside though has been the terrible cough from acid reflux. Neither of these was covered in the info about the medication when I started, so makes one wider what other benefits or side effects will arrise over time as more people report on it.
Well rounded research with a what felt like a bit of a bias for Ozempic. The systemic issues are incredibly difficult to overcome given the inconsistencies among nutritionists, the "organic food" lies and the kind of ingredients that processed food makers are allowed to use. The cultural issues are even worse when friends, family and workplaces create environments with incredibly unhealthy foods. Having a child really opened up my eyes when reading the ingredients on labels and I still have a lot of uncertainties on what I need to avoid.
I have had no negative side effects and have lost about 60 lbs in 7 months. I feel free and like a “normal” person even though I still have a ways to go on my weight loss journey.
This video took a turn…. It really spelled out how these drugs and drug companies take advantage of consumers but its okay to band aid the problem? Some one please explain.
I lost 27kg in two years of Ozempic use paired with a new diet and exercises. I went from obese to slight overweight and I cannot stress enough how my mental health, my self-esteem and my overall health improved. It was under medical prescription and monitoring, and our goal was to use the drug as a tool, not as a clutch. Thus, I’m lowering the dose in order to eventually phase it out and focus solely on exercises, but I cannot deny how transformative Ozempic was, the push it gave me to actually pursue a better life. And in all honesty, looking better is the good side effect for me.
The issue is simple and it's been simple the entire time, it's literally staring us in the face. OUR FOOD/DIET HEALTH APPARATUS IS ABSOLUTELY BROKEN. High use of meat in every meal, high use of simple carbs in every meal, low levels of fiber, low levels of fruits, legumes and vegetables. We are fed nutritionally deficient foods at every turn. Real food is more expensive than highly processed foods. We are constantly looking for an easy way out of the pit when ever year the obesity levels increase. There is no easy way out. We allow food lobbies to tell us what to eat and what is ok to put in food when their main aim is cheaper processes and more profit. It's literally killing the population off slowly. Real solutions Upend the system return to less commercial farming practices diversify the plate! Reduce the meat consumption bread and milk consumption. Increase the plant and fruit consumption. We are literally staved and fat at the same time... No one medical "miracle" will fix the issue. We always want the silver bullet there isn't one! Someone in authority needs to be honest!
True. What we eat is the most important aspect. Plus, the amount we eat. In the US, it’s so normal to eat crappy food until we feel sick from how full we are. We should never be so full, yet we do it everyday. That, coupled with the lack of exercise in most peoples’ lives… it’s just sad. They bred this.
You must be young and don't realize how we were feed back in the '80s / '90s. Food wasn't healthy or unhealthy, but we ate less of it. I grew up eating a lot of meat, milk, cheese, normal amount of vegetables and a lot of carbs. My Mom never fixed a vegetable with spaghetti. It was served with more carbs, bread.
But, we weren't as gluttonous. Also, we just naturally moved around. It was watching TV, reading or go outside. I left high school weighing 135lbs being 5' 10".
Plus too much money is being made, this video in the end was still a marketing tool for Novo Nordisk's $500 billion market cap.
The solution to trash health in scamerica is identical to what civilizations did for thousands of years, vegetables, fruits and being active. Aka burn more calories than you consume.
Post it notes. I'll do it. You can too. I go to the grocery store often. We can do something and talking about it does it. Someone will listen
Meat isn’t the problem, in most cases it’s highly palatable foods/ drinks that aren’t satiating. Think chips, cookies, donuts, soda, etc. Meat, fruit, and vegetables are all much more satiating than processed food, so we naturally cannot overeat them.
While fruits and vegetables are important for overall health, meat is critical for getting enough protein unless you are pounding plant-based protein powder every day. It helps to retain and build muscle which is critical.
As a physician, I really appreciate this more nuanced take on the GLP-1 madness that has been taking all forms of media! Thank you!
It's too expensive. I'd rather take Lizzo.
It is significantly cheaper in China and other part of the world, also it is not knock off. It is more like a problem of US health industry.
@@Theoryofcatsndogs about 60 dollars in china, france, danmark and germany. here in brazil it's absurd. a monthly cost of wegovy is 2400 reais while a monthly minimum wage is 1400 reais. also no insurance coverage here, every pen is full price out of the pocket.
Easy and simple are not the same. Eat less, move more is simple not easy.
The biggest issue I've found is that there is no supply of low doses of Weygovy and that health insurance doesn't cover enough of the med Zepbound. Other drugs aren't approved for weight loss only, and providers will not prescribe other GLP1s. Supply issues and access to the drugs are a bigger issue.
I watched this entire thing. Everything about this sounds like a long commercial to sell these drugs. I wonder if Business Insider got paid by the drug companies?
This drug works for me. Of course everybody has different situation. My doctor put me on this med four years ago for my fatty liver which has caused my liver fibrosis. Lost about 32 lbs in four years gradually. My fatty liver is reduced dramatically. For decades, my recent blood work shows my liver numbers in normal range for the first time. My blood sugar is also under control now. All meds have side effects. We need to look at what individual situation is. You cannot stop eating just because you got chocked.
I lost 30lbs on a compounded GLP1. For me, the drug helps with addiction. I always had food noise and was thinking of the next meal. That noise has gone away. When I am comfortably full I can "push-away" the plate of food. I also developed sleep apnea which is not cured, but under control. Due to the lack of sleep I drank a lot of caffeine. After 1 week on a GLP1 i drink maybe a 1/2 cup a day now.
Others has reported decrease in alcohol consumption. I was never a big drinker.
I'm really confused, because the thesis seemed to be that we need to turn down the hype, but all the supporting detailed seemed to confirm it was worth the hype.
I think the idea is to turn down the extreme-hype from "omg miracle drug" down to a moderate hype of something like "These drugs work decently well".
Something can be overrated while still being functional and useful.
My issue is that the us gov fronts a lot of money to pay for this
Because it works and they don't want to have to pay medicate costs for an obese ageing population when there is a medicine that helps reduce their over all costs. The US is partially socialized medicine, and the gov wants to use drugs that save them money in the long run. Even though what we really need is better quality food becuase food in the US is shit.
@ I don’t think I can add links here. But there’s a video on TH-cam about how ozempic is very very expensive for a medicine being used as a preventative.
@ you’re right though about it being a way bigger issue than just some
People wanting to take a drug to be skinny
Any article with “could?” Or “may” or “might” about effects of anything is wasting your time so much that you should sue the publisher.
How much BI get paid for this advertisement?
"Weight loss" is a mirage. Emotional and physical health should be the goal.
Business insider GOT PAID
yep lol
@@kutie216you have a theory and you apply it whenever you see mention of drugs. Simple world view. It’s possible it helps many, many people AND pharma companies are not good actors. Hard to keep two things in brain at once?
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We just need to start treating addictive junk food the same way we treat cigarettes. Health education campaign, banning them from schools, warning labels, and heavy taxes that can be used to offset the healthcare costs. Instead, our government literally subsidizes these addictive foods, making them cheaper than real food.
Fantastic journalism. Business Insider is such a gem when it comes to news and information nowadays.
lol, journalism?
@@bassandtrebleclef Troll much? And who uses lol anymore like that? How out of touch are you?
I tried metformin and got horribly dizzy couldn’t take it. Trulicity gave me hives. Ozempic worked great for me. Ultimately everyone is different and you have to find the right thing for you.
Greed and stupidity is leading to our well deserved extintion, I just feel bad for all the other species.
How can half of patients stop taking them after a year and 70% stop taking them at the 2 year mark? That is 120% of patients.
So this is basically an ad for ozempic
Exactly how I see it
I've gone from 233 pounds to 188 pounds and from A1C of 9 down to 5. All of my markers have improved and I am no longer taking any other meds, including insulin. I also began working out with weights a year ago and look better now than I did in my 20s.
I appreciate what you reported I can also say that like most journalists you don’t understand research. Citing the conclusions of papers is meaningless if you don’t look at the validity of the study. I will point just one of about 5 examples I could cite.
The first study you looked at that says the average loss from exercise and diet alone is only 2.4% That means that the people in that group did NOT actually follow a VALID diet and exercise program. Unless of course you believe that diet and exercise can only shed 7 1/2 pounds from a 300 pound person. That obviously is nonsense therefor making the study nonsense.
The only study that would compare how well ozempic works would be to compare how a REAL diet and exercise program, one that is followed, compares to using Ozempic ALONE. Don’t look at the results after 6 months because that is meaningless unless you plan on being dead in 6 months.
If you don’t change your eating habits nothing works long term, and that is the only message that helps people.
10 minutes into the video, it sounds like an guerilla marketing campaign for Ozempic especially now that the sales have plateaued and soon we'll have generic versions.
She was literally prescribed a generic version, which she shows on camera. Two of the main messages are that it doesn't work in the entire population and that you will probably regain the weight after stopping the medication. Certainly not the best advertising campaign for a company.
I just started my treatment about three weeks ago. I’ve lost 6 lbs. My hunger has decreased, but I’ve noticed that my mind keeps trying to tell me I should be eating. It’s a battle I have to fight everyday at least now I’m not also really “hungry” all the time.
I started using Suxenda about a year and a half ago and barely saw any results and the fact that it required a daily injection was just too much for me especially with the severe GI side effects constant nausea and about 1-2 vomits daily with no real benefit then I switched to Ozempic which was very similar in results but at least it was a once a week injection so it wasn’t as bad but the real game changer for me was Monjaro (Tirzepatide) it had much less side effects and a much more pronounced weight loss. So the moral of the story I guess is that for those who don’t see results with a certain drug maybe consider trying a different one
Ive had no side effects dont let this chick scare you this med is a true miracle and honestly ive never been healthier.
This craze for these meds has meant for that over 2 years I have to ration my medication because I was put on it for diabetes when other meds didn’t work. They are harming diabetics I order to lose a few lbs. The shortage is less bad than before, but please don’t push it for other things. It’s a lot more dangerous for someone who can’t get their blood sugar under control because of the shortage than it is for someone who is sad they can’t have a baby or who wants to lose a few lbs.
I did 2 cycles of Ozempic .5mg a week with 45 off days in between each cycle. I lost about 18lbs but I now have severe gallbladder cholecystitis. My doctor has recommended I remove my gallbladder but I will first be trying some natural remedies and dieting before going under the knife. Just thought I would share my experience. The pain is just unbearable!!!