Synthetic virology | Andrew Hessel | TEDxDanubia

Andrew Hessel designs synthetic viruses and uses the latest 3D printing technology to create medicine that is designed individually for a single patient. The promise here is that once he succeeds to design a synthetic virus that is able to penetrate the medicine throughout the body of the patient, he can scale the solution and present the world an almost free and much more capable medicine against cancer.
Andrew Hessel szintetikus vírusokat fejleszt digitális genetikai tervezéssel. Laptopjával, egy speciális programmal és a legmodernebb 3D nyomtatás segítségével személyre szabott gyógyszerekkel sokkal hatékonyabb rákgyógyszerek előállítása a célja. Az új technológiákkal a hagyományos gyógyszerkutatásnál olcsóbban és hatékonyabban lehetséges sikeresen terjedő, a rákot elpusztító gyógyszert fejleszteni. Ha megvan a formula, akkor meg már csak a tömeggyártás maras hátra és legyőzhetjük a rákot.
In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

[@tris73]

I simply don't understand WHY this presentation have only 1363 views. Yes "The man is a giant."

[@schnitzelschnizel9448]

You are right.

[@Biomeducated]

100% agreed! I'm spreading this one further. NOW, 2020!

[@harizhazwan]

I only comment on TH-cam few times since using internet, and I'm in my mid-20s. But I have to comment now to point out that this got to be the most interesting and most important TEDTalk video, ever.

+Hariz Hazwan Without any single doubt!

[@khurtsiya]

Totally agree!

[@aoihana1042]

This video sparked a fire in me

[@florencevandermeer9447]

So, what happened?

[@tartanhandbag]

i also had this idea a few years ago (like, a decade after craig venter et al, of course, lol) but he is not really mentioning the missing link; the difficult bit that makes this technology hard to pull off: knowing what to print. he makes it sound easy, but science/genetics has a long way to go and he downplays this. there are similar strategies involving synthetic antibodies, but in both cases, antibodies, viruses or otherwise, we're not quite at the stage of being able to manipulate DNA and the host cell used for protein expression well enough to perfectly code for the necessary protein shape. there are so many complexities involving protein folding, post-translational modification, getting the chosen particle into a state that can be harvested correctly. not everything can be made in bacteria, let alone a single strain of E coli. Of course the speaker knows this, is aware of the problems and presumably expects other technologies to come in and solve some of these problems as time goes by and that as those barriers fall, this dream (and his company) will take steps towards becoming reality, but we have a long way to go to cover all he is promising and he does not address this at all coz it's a TED talk and it's supposed to sound like the greatest thing ever. i would argue that bacteriophage therapies will come first as an alternative to antibiotics, then proper availability of oncolytic viruses may come later, followed by antibodies and eventually the imagination is the limit (both for better and for worse).

[@medichain]

This talk was in 2014. I wonder how far he has come now, at the end of 2018.

[@tartanhandbag]

@@medichain I haven't heard of any major breakthroughs. This guy is still pedlling the same talk. What he is suggesting requires the confluence of many different fields of molecular/synthetic biology.

[@vegeta3993]

This technology could be used to cure other diseases such as ebola or AIDS. Amazing work!

[@DanielMOFO]

I am legend, here we come.

[@Tany12great]

This stuff is mind blowing !!!!!

[@Tany12great]

Can it fight Corona and the viruses that have yet to come ?

[@sebas11tian]

This is quite amazing! Ideas focussed on a problem using new technologies being wrapped up with a surprising business model. Thank you mr Andrew Hessel :D

[@blu12gaming44]

The greatest fear I have with this is ambition overtaking caution when developing new treatments. The idea for the wifi-capable DNA synthesizer in a pen is a perfect example, just imagine malware being put out there for the things & sick people inject themselves with them.
Nothing is a magical pill and Murphy's Law should always be considered when coming up with new designs. You can't just "Go back to the design table" as Hessel called it if there are several bodies left in your wake.

[@shikhantsaini1786]

One of the best Tedx talk ever. But i had a question, that could this technology be used to create ebola or other deadly viruses, like vsauce said?

[@lorenzweb]

Yes, easy. But a handy molecular biologist could already do that today with current bio technology.

[@kiankelly6442]

I'm a sophmore undergrad in cell & mollecular biology. I am currently doing research genetically engineering viruses (in my case human Cytomegalovirus virus). We are knocking out genes in the virus and infecting cells in order to identify which genes are most critical to virulence for targeted therapies. This virus kills 60k people per year. So yeah, it's pretty easy, but I promise I want to help people not kill them.

[@splitpersonalityproduction1030]

Could this technology be used to create The coronavirus???

[@archa1624]

this is beautiful idea, I wonder how they are doing now.

[@Ash-zb7bu]

This talk is amazing and so eye-opening for me. I Can't believe I'm only watching this now! Definitely needs more views.

[@tugan0329]

Amazing ideas! Really thoughtful solution to the current problems of cancer drug.

[@muraleekrishnaviswanadh]

Really Awesome, i see the future disease diagnosing in your speech.

[@TheAncientOneOfDays]

WOW... Why is this the First time I'm hearing about this work and this subject.... I am getting involved

[@rotmgWevouls]

I came here interested in computer viruses and still found this to be interesting

[@jayalalkj1576]

Great and smart thinking.

[@LilmissJessicaRabbit]

This is EXACTLY the technology they use in Star Trek... Go figure

[@maitre_de_la_maison]

I hope there's been some progress made on it .And we see a day in our life time to see this as new normal

[@addig1696]

brilliant!

[@jooky87]

Wow, seriously. Wow.

[@asunciondiezarce1828]

Very interesting.Thanks

[@PrettiBoiMicah]

Fantastic 👍

[@binadam9459]

This an Idea that worth spreading

[@arischwartz9593]

so where is the site i can start doing this from?

[@koruki]

Maybe its me, but I see Steve Jobs silhouette at 17:12

[@h13000]

I wonder if the graph is inflation-adjusted

[@HugoMejia]

The graph shown said it was inflation-adjusted.

[@HML2004]

Important skill to have. Learn how to make it.

[@edwardfrancois1100]

This is pretty cool. How do you contact Andrew Hessel ?

[@santircastillo]

WOW!

[@carolined5923]

Corona virus 2020.

[@wejsmith5446]

Yo pass me a Corona

[@Lucy-vk1el]

Isn't this the plot from I am Legend?

[@-gladys-5276]

50 comentarios para una explicacion tan interesante

[@nertoni]

It's not so easy as he explained.