G Protein Coupled Receptors | Nervous system physiology | NCLEX-RN | Khan Academy

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  • เผยแพร่เมื่อ 8 ก.พ. 2025
  • Learn about how g protein coupled receptors work in the cell membrane. Created by William Tsai.
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ความคิดเห็น • 375

  • @dexkani9993
    @dexkani9993 10 หลายเดือนก่อน +55

    Bruh, it's been 9 years, this video needs a re-edit for those precious minutes gone while it was zoomed in

  • @msauthor4989
    @msauthor4989 3 ปีที่แล้ว +273

    This guy taught me better in 12 minutes than my professor did in a 45 min class. Kudos dude.

    • @naveedkhankakar144
      @naveedkhankakar144 3 ปีที่แล้ว +7

      and my one took more than an hour.

    • @sadah22
      @sadah22 3 ปีที่แล้ว +5

      @@naveedkhankakar144 and mine took more than five hours 😫.

    • @fizazainab1526
      @fizazainab1526 3 ปีที่แล้ว +4

      Hahahhaha we are in same category

    • @naveedkhankakar144
      @naveedkhankakar144 3 ปีที่แล้ว +4

      @@fizazainab1526 hahahaha yup we are.

    • @fizazainab1526
      @fizazainab1526 3 ปีที่แล้ว +3

      @@naveedkhankakar144 good luck for your future

  • @asmahaque8558
    @asmahaque8558 6 ปีที่แล้ว +207

    I HAVE SPENT 2 YEARS IN MED SCHOOL MANEUVERING MY WAY THROUGH COUJTLESS EXAMS AND VIVAS WITHOUT EVER REALLY UNDERSTANDING THIS! UNTIL TODAY! THANK YOU

    • @ozymandias5449
      @ozymandias5449 4 ปีที่แล้ว +8

      this is me right now haha

    • @Urtoomuchjosh
      @Urtoomuchjosh 4 ปีที่แล้ว +27

      thats kinda sad

    • @chenchoon8751
      @chenchoon8751 2 ปีที่แล้ว +2

      Did you graduate yet? If so, congratz!

    • @godferymbadiwe4754
      @godferymbadiwe4754 ปีที่แล้ว

      How far
      I need a mentor. I just got into my first year of medical school

  • @Mrjmaxted0291
    @Mrjmaxted0291 6 ปีที่แล้ว +185

    Besides the VERY MINOR flaw in remaining zoomed in during a certain segment this was a very succinct and well presented lesson on GPCRs. Thanks for posting it up, it's been a great overview to revising the key concepts.

  • @DollyDomDom
    @DollyDomDom 3 ปีที่แล้ว +68

    This was perfect! The only thing this video missed was that after ATP is converted to CAMP, CAMP then goes on to activate Protein Kinase A to THEN produce the physiological effects.

    • @gmmg834
      @gmmg834 2 ปีที่แล้ว +2

      Thank you for your contribution

    • @juliana-qf
      @juliana-qf ปีที่แล้ว +1

      to talk about this would be a specific video about the second messengers

  • @ttaylorfaithh
    @ttaylorfaithh 9 ปีที่แล้ว +743

    why did the video zoom in so much i can't see~~!!

  • @nonewthing2883
    @nonewthing2883 2 ปีที่แล้ว +3

    This guy taught me better in 12 minutes than my lecturer did in a 2 hour class. Levels, thanks dude.

  • @danjbundrick
    @danjbundrick 9 ปีที่แล้ว +139

    Except for the zooming error, this video was a spot on. Thank you. I heard that it was called "adenylyl cyclase" though.

    • @danjbundrick
      @danjbundrick 9 ปีที่แล้ว +2

      +Jai A Meyrick Thanks. I'll have to remember that.

    • @danielortega494
      @danielortega494 8 ปีที่แล้ว

      Daniel Bundrick g

    • @Vikramt08
      @Vikramt08 5 ปีที่แล้ว

      Adenylate cyclase

    • @jayrabah8064
      @jayrabah8064 5 ปีที่แล้ว +2

      It does the same thing ,but it’s an amplifier enzyme so I think there must be a difference

    • @hobobazaar8196
      @hobobazaar8196 2 ปีที่แล้ว +2

      Adenylate cyclase, adenyl cyclase, & adenylyl cyclase are all the same enzyme. Confusing redundant names, that's science.

  • @nels6991
    @nels6991 8 ปีที่แล้ว +174

    Great video! FYI the zoom only lasts for like 30 seconds yall ;)

    • @a.stuckmann431
      @a.stuckmann431 4 ปีที่แล้ว +3

      more like 1 -minute......

    • @jonahansen
      @jonahansen 3 ปีที่แล้ว +1

      It goes from 4:03 to 5:23 for a total of 1:20 or 1 minute and 20 seconds, plus or minus a few seconds.

    • @materialgowrl1553
      @materialgowrl1553 10 หลายเดือนก่อน

      well with subject like this, every second is crucial, the dude fucked me up

  • @jjocelynjustice
    @jjocelynjustice 9 ปีที่แล้ว +42

    This video helped the concept of G proteins finally click in my brain. Thank you!

    • @santheeshsantheesh5746
      @santheeshsantheesh5746 5 ปีที่แล้ว

      Jocelyn Justice go for The Great Dr.Najeeb if you really want to build your concept

  • @joeanderson7841
    @joeanderson7841 9 ปีที่แล้ว +41

    Thank you sir, it helps me a lot for my final exam

  • @stephyunion
    @stephyunion 7 ปีที่แล้ว +19

    I like the way you explain this 5-full-pages theory in a simple way. Thank you! This helps me for my tomorrow exam ehehehe

  • @tiruvgiri1519
    @tiruvgiri1519 5 ปีที่แล้ว +6

    How hours of boring lectures are made into a 12 min riveting knowledge is always going to be a mystery to me #Khanacademy.
    Thank You for saving my life btw

  • @hudhaifaahmed5738
    @hudhaifaahmed5738 2 หลายเดือนก่อน +1

    This is the best video explaining GPCRs out there. Tysm

  • @cmgkk
    @cmgkk 10 ปีที่แล้ว +7

    Great clear explanation. I studied this back in undergrad and want to carry out an experiment now in my PhD where I inhibit G-alphaS and see downstream function. I need a quick re-fresher and this hit the spot! Thanks!

    • @roselynyeboah5974
      @roselynyeboah5974 4 หลายเดือนก่อน

      I tell you am wid u on this one same here am good to go now😅

  • @DuyNguyen-qv3pi
    @DuyNguyen-qv3pi ปีที่แล้ว +3

    Thank you so much. I went through my lecture slides, recording but still not understanding a piece of information like you did in 12 minutes. I am so grateful to be here with other students.

    • @exemplarypersonality6562
      @exemplarypersonality6562 11 หลายเดือนก่อน +1

      Same here, the lecture and audio from my boring lecturer was always inducing sleep

  • @thanatosiax
    @thanatosiax ปีที่แล้ว +1

    MY PROFESSORS COULD NEVERRR. THANK YOUU 🥹🫶🏼

  • @FarheenFathima397
    @FarheenFathima397 4 ปีที่แล้ว +2

    Greatest video ever. loved it. Thank you for being alive.

  • @nampotiwong9863
    @nampotiwong9863 3 ปีที่แล้ว +1

    This video saves my 1st year as a medical student!!!!! Thank you so much!!!!!

  • @Hamzahaisha-fu7mf
    @Hamzahaisha-fu7mf 2 หลายเดือนก่อน

    I can't unlearn this ,you deserve a huge hug for this❤❤

  • @mennatallahmaher5967
    @mennatallahmaher5967 2 หลายเดือนก่อน +1

    Amazing I love it ❤❤❤

  • @alisthompson
    @alisthompson 8 ปีที่แล้ว +238

    Please fix the zooming issue!

    • @oxysmoxy1977
      @oxysmoxy1977 7 ปีที่แล้ว +1

      You have to change it to full screen, it worked for me :)

    • @sherhorse
      @sherhorse 4 ปีที่แล้ว +10

      @@oxysmoxy1977 doesn't work

  • @jess100ize
    @jess100ize 6 ปีที่แล้ว +6

    What would I do without Khanacademy?? Great explanation, as always😁👌🏼

  • @dilaozut
    @dilaozut 5 ปีที่แล้ว +1

    Your speech was so clean that despite my poor english i could have understood you well. thank you :)

  • @HashemSmashem
    @HashemSmashem 7 ปีที่แล้ว +13

    Lol did a cat jump on your notes @7:45? 😂 Awesome, clear, accurate, and well explained video btw. The zooming-in issue wasn't very hindering in terms of understanding the concept, but it would be that much better if it was fixed. 9/10

  • @leerunkang8237
    @leerunkang8237 2 ปีที่แล้ว

    Thank you for the simplest , you explain better than my professors at the collage and for free

  • @SoulPure-77
    @SoulPure-77 10 ปีที่แล้ว +8

    Brilliant. Really helpful.! Thanks a lot

  • @eliawilckriph1269
    @eliawilckriph1269 ปีที่แล้ว

    for the first time iunderstand the concept of GPCRs. Thank you

  • @Lana-wu2po
    @Lana-wu2po 3 หลายเดือนก่อน

    So good. Worth my time

  • @N98-l4n
    @N98-l4n 6 ปีที่แล้ว +1

    EXACTLY what i was looking for!! thank you!!

  • @rubyyxlc3936
    @rubyyxlc3936 7 ปีที่แล้ว +17

    5:23 continued from zoom out

  • @lizj8921
    @lizj8921 6 ปีที่แล้ว

    Made this sooo much easier to understand!

  • @sarabe2930
    @sarabe2930 9 ปีที่แล้ว

    i couldnt get the topic on my lecture but now it is all clear! thanks a lot! Thumbs up :)

  • @loserlover6668
    @loserlover6668 3 หลายเดือนก่อน

    Omg! I love this channel

  • @humzaalam4823
    @humzaalam4823 2 ปีที่แล้ว +1

    This helps us so much even if it was made 8 yrs ago

  • @shaikhsimran735
    @shaikhsimran735 หลายเดือนก่อน

    Very nice explaination sir. Thank you so much 😊

  • @katefuglestad5894
    @katefuglestad5894 2 ปีที่แล้ว

    Very helpful! Thank you. The visual really helped.

  • @learnteach2learn729
    @learnteach2learn729 6 ปีที่แล้ว +1

    tHIS MAKES SO MUCH SENSE

  • @anaherrera4805
    @anaherrera4805 2 ปีที่แล้ว

    Excellent explanation!! Thank you

  • @hinashaukat246
    @hinashaukat246 4 ปีที่แล้ว

    Finally got the concept of g protein ,thanku for this work 👍

  • @andreeadavidean2787
    @andreeadavidean2787 2 ปีที่แล้ว

    Thank you, i finally understood this!

  • @zainebmazin6274
    @zainebmazin6274 4 ปีที่แล้ว

    I’m so thankful ❤️❤️❤️❤️❤️ for this video

    • @memuethel4910
      @memuethel4910 4 ปีที่แล้ว

      I'm overwhelmed with joy, I finally passed my NCLEX RN after three trials and I almost gave up until I met this God sent. Please join me celebrate my helper Dr Brooks for his consistent assistance showed to me during my preparations for this exam. If you want nclex to be history to you, contact Dr Brooks via text or whatsapp on +12404085402.

  • @colindaines3552
    @colindaines3552 4 ปีที่แล้ว

    Super helpful video!

  • @jonxthxn1
    @jonxthxn1 ปีที่แล้ว

    Thank you so much for this!

  • @atulprasadarya8873
    @atulprasadarya8873 6 ปีที่แล้ว

    Way of teaching adorable...

  • @rocketbabydoll93
    @rocketbabydoll93 9 ปีที่แล้ว +2

    This video is my lifesaver. Thank you so much!

  • @dr.zaina.0
    @dr.zaina.0 2 ปีที่แล้ว

    Thank you very much that’s help me more 🙌❤

  • @xrelaxbear
    @xrelaxbear 7 ปีที่แล้ว

    thank you so much, i learned more from this video than i did in a 2 hour college lecture..

  • @jadattia6723
    @jadattia6723 7 ปีที่แล้ว +2

    great job . thanks from Syria

  • @AJ-rd6ez
    @AJ-rd6ez 4 ปีที่แล้ว

    Wow this is SO helpful!!!!! Thank you

  • @ruksanakhan4989
    @ruksanakhan4989 4 ปีที่แล้ว

    Informative video... thnx a lot

  • @adenmadi
    @adenmadi 3 ปีที่แล้ว

    Thnx for the explaination 👍

  • @gaiaromualdi
    @gaiaromualdi ปีที่แล้ว +1

    Thank you😭😭😭

  • @anilocm5457
    @anilocm5457 4 ปีที่แล้ว +1

    This is a savior 👏

  • @chenlynn951
    @chenlynn951 10 ปีที่แล้ว

    WONDERFUL!!! I learned more from this video than my 3-hour-long graduate class!!! THANK YOU VERY MUCH!!!

  • @الثبات-ل2ط
    @الثبات-ل2ط 5 ปีที่แล้ว

    Thank you! Good video

  • @maryamsed6023
    @maryamsed6023 6 ปีที่แล้ว +1

    Woow thank u so much, u explained such a hard tissue sooo easily and clearrrr, ur greattt

  • @kinkinib
    @kinkinib 7 ปีที่แล้ว

    Thank god for Khan Academy

  • @poojachaudhari1331
    @poojachaudhari1331 3 ปีที่แล้ว

    What an excellent explanation

  • @anwaralshafy4472
    @anwaralshafy4472 5 ปีที่แล้ว

    Amazing video ❤

  • @juandiegodistefano335
    @juandiegodistefano335 4 ปีที่แล้ว

    This video was amazing.

  • @soumyanag2328
    @soumyanag2328 5 ปีที่แล้ว

    You have just activated my G-Protein awsm Khan Academy Simple Smart and Conceptual what else do we need

  • @luisrm37
    @luisrm37 5 ปีที่แล้ว

    Wow that was great!

  • @johnmulemwa6609
    @johnmulemwa6609 10 ปีที่แล้ว +11

    Wish harper's was easily understood as this........

  • @shadychapook3944
    @shadychapook3944 3 ปีที่แล้ว

    Thank u so much it was soooooo useful ♥️

  • @evaafif7239
    @evaafif7239 4 ปีที่แล้ว

    Really helpful 💕

  • @friendspark587
    @friendspark587 4 ปีที่แล้ว

    Thank you so much for this. Really clear and helpful. God bless you❤❤❤❤❤❤❤

  • @hippocampus4910
    @hippocampus4910 3 ปีที่แล้ว

    Excellent 👏

  • @arunabhSiddhartha
    @arunabhSiddhartha 8 ปีที่แล้ว

    Very well explained!

  • @ch-p2861
    @ch-p2861 7 ปีที่แล้ว

    Great video! Thanks so much!

  • @HoosierHmstrdr94
    @HoosierHmstrdr94 2 ปีที่แล้ว +2

    The zoom problem doesn't last long and you can see what happened shortly after it is corrected. Be patient. You'll get it!

  • @momikhattak5533
    @momikhattak5533 2 ปีที่แล้ว

    Nice explanation

  • @aleenasajan936
    @aleenasajan936 ปีที่แล้ว

    Thank you sir 😇🙏🏻

  • @adlinanatashaamirudin8999
    @adlinanatashaamirudin8999 8 ปีที่แล้ว

    It helps me a lot!! lots of thanks.. it's very clear and simple.

  • @Wessam12345678910
    @Wessam12345678910 9 ปีที่แล้ว +1

    Perfect explanation... thank you alot!

  • @princemulenga1621
    @princemulenga1621 2 ปีที่แล้ว

    Amazing explanation, simple and straight to the point. thank you!!!

  • @roshanibhavsar1756
    @roshanibhavsar1756 6 ปีที่แล้ว

    Awesome video sir 😍😍😘😘👌👌👌tx sir🙏🙏

  • @triduong6855
    @triduong6855 6 ปีที่แล้ว

    thank u so so much. This video is very great!

  • @christopherh.7008
    @christopherh.7008 9 ปีที่แล้ว

    Great Video! Thank You

  • @AK-ut3id
    @AK-ut3id 10 ปีที่แล้ว +3

    Thank you. Absolutely amazing! :)

  • @racheldenapoli2278
    @racheldenapoli2278 5 ปีที่แล้ว

    Thank you so much I am forever grateful.

  • @SiberianHuskyF1
    @SiberianHuskyF1 9 ปีที่แล้ว +2

    Thank you :) You've made final year physiology a little easier.

    • @AlanRasoulMentor
      @AlanRasoulMentor 9 ปีที่แล้ว +3

      what! you were whatching this on your final year?

    • @drnykterstein_
      @drnykterstein_ 9 ปีที่แล้ว +4

      we read this on first year

  • @srkzn5304
    @srkzn5304 6 ปีที่แล้ว

    You are awesome! thank you so much!!

  • @dhananjaymangal9910
    @dhananjaymangal9910 8 ปีที่แล้ว

    very nice presentation...

  • @danialk8435
    @danialk8435 6 ปีที่แล้ว

    Good video.
    Killed it.

  • @margaretmora1081
    @margaretmora1081 4 ปีที่แล้ว

    Wonderful and clear! Thank you!

  • @taiganakazawa1390
    @taiganakazawa1390 10 ปีที่แล้ว

    very good video, thank you very much!

  • @juleschannel3934
    @juleschannel3934 5 ปีที่แล้ว

    Well done, great video!

  • @KMedina514
    @KMedina514 8 ปีที่แล้ว

    great explanation!

  • @imani6547
    @imani6547 2 ปีที่แล้ว

    Thank God for you

  • @mahmoudahmed3468
    @mahmoudahmed3468 3 ปีที่แล้ว

    This kind of videos doesn't even deserve 1 dislike ❤️❤️

  • @shankaraiahgoudmamidi4601
    @shankaraiahgoudmamidi4601 7 ปีที่แล้ว

    That was a very useful and helpful video

  • @EvilMia1
    @EvilMia1 10 ปีที่แล้ว +8

    Greetings from Sweden! Thanks for a great video! Dont know if it really matters, but it's an adenylyl cyclase (not adenylate) according to my biochemistry book.

    • @hjorthan
      @hjorthan 10 ปีที่แล้ว +3

      Both terms are used. I just checked two of my danish textbooks. Biochem-book says 'adenylate' and Pharma-book says 'adenylyl'. But I also seem to recall that previous english textbooks I've read uses 'adenylate'. I guess it's just a 'cultural' thing, regarding what system you use to name the functional groups.

    • @passcomcompass2623
      @passcomcompass2623 10 ปีที่แล้ว +1

      Both terms are used, adenylyl is kind of an old fashioned name, some of the pictures of researches my lecturer shown us use adenylyl, but adenylate is used in most universities in London as as far as I know.

    • @mermaidtale1
      @mermaidtale1 7 ปีที่แล้ว

      they use both here at the University of Otago :)

  • @kobingsubu
    @kobingsubu 6 ปีที่แล้ว +9

    Wow , very well explained 👏👏 i always get scared when i hear g protein coupled receptors (sounds scary right) but now that ive tried to understand its so simple thanks khan academy

  • @drdivishaverma6242
    @drdivishaverma6242 8 ปีที่แล้ว +7

    too good! 👍🏻

  • @sindhulatha9376
    @sindhulatha9376 10 ปีที่แล้ว

    thanku for teaching,its awosome....

  • @bwiremartin805
    @bwiremartin805 2 ปีที่แล้ว +1

    please help me with the kind of textbook
    that you guys use
    its really very well understood

  • @Adhikash015
    @Adhikash015 7 ปีที่แล้ว

    Thank you soo much for this video man....

  • @khamikos1
    @khamikos1 7 ปีที่แล้ว

    excellent presentation. perfect. thanks from Greec

  • @amreshrandive5371
    @amreshrandive5371 9 ปีที่แล้ว

    Very Helpful explanation. Thank you.