Lipoprotein Electrophoresis

Lipoprotein electrophoresis is the technique used to separate lipoproteins in the serum. Each lipoprotein band in the lipoporotein electrophoresis slide can be quantitated.
Lipoprotein electrophoresis was performed on serum from subjects with and without coronary heart disease, and the patterns compared with the serum concentrations of triglyceride and cholesterol. The beta- and pre-beta-lipoproteins, expressed as a percentage of the total lipoprotein, correlate strongly with the cholesterol and triglyceride concentrations, respectively. The beta- and pre-beta-lipoprotein concentrations are even more strongly correlated with these lipid measurements. The lipoprotein pattern does not have greater discriminant value for coronary heart disease than does the triglyceride or cholesterol concentration. There would seem to be little justification for the use of lipoprotein electrophoresis in screening the general population for coronary heart disease.
Reference: Br Med J. 1971 Jan 9; 1(5740): 78-82.
You can watch my video on lipoprotein metabolism in the link below:
• Lipoprotein Metabolism...
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[@VijayaMarakala]

Knowledge shared is knowledge gained. Definitely many students will be benefited from your videos.

[@DrMungli]

Thats true Dr Vijay. I'm glad if these videos be helpful to students in need.

[@navaneeth6744]

Sir I am downloading all your videos. I have recommended yours to my students. My hats off to entire videos both past and future

[@DrMungli]

You are most welcome to download them for personal use. Thank you for recommending my videos to your students. I'm glad these videos are helpful. by the way are you teaching to graduate or post-graduate students, like which college and place in India.

[@navaneeth6744]

Sir At ESI medical college KK Nagar, Chennai, Tamilnadu. I am a physiologist

[@DrMungli]

Happy to know, hope these videos are helpful to your students. Please let me know if you want me to cover on any special topics.

[@DineshDinesh-yp2mk]

Best ever explanation sir.... I understood very well... thank you so much

[@bhu9984]

Sir I have a doubt in electrophoresis at pH>pI Why do anion move towards anode? And at pH

[@be-utiful8569]

Awesome Sir

[@AnjorinOmotola]

Good job!🎉

[@DrMungli]

Thank you

[@nadab5675]

Thank you so much, that was so helpful

[@DrMungli]

Glad it was helpful!

[@Mariiiam]

Thanks Sir

[@narasimha7870]

Sir why vldl is called pre beta,it is after beta so it should be post beta right??

[@shereenjadallh8867]

thank you sir it was very helpful

[@DrMungli]

You are welcome.

[@Lee-O1-]

thank you sir

[@DrMungli]

You are most welcome.

[@AbdolazimHasseli]

Sir, thank you for your explanation. Is this the method labs measure the blood hdl, ldl and triglycirides?

[@dragutte3742]

This is golden

[@anneliemaria3158]

That was so helpful, thanks

[@tomcruise9317]

Idl where will be placed sir

[@DrMungli]

In between LDL and VLDL.

[@lostSempaiWissame]

Why is LDL before VLDL even though LDL is lighter ????

[@sanjithkarthikeyan3023]

Electrophoresis doesn't depend only on weight. Depends on charge too. LDL has only apo b 100 while vldl has extra lipoprotein making it more negatively charged. Hence goes further distance to the positive side

[@youthsociety7459]

sir electroprosis
Ldl
vldl
chylomicron level decreases
and ph 8.6
cholesteol level 654
which type of hyperliporotenima
plz give me ans

[@DrMungli]

Did not quite get your question. You can share the entire question or the report so that I can interpret.

[@youthsociety7459]

sir
i have full question
how to send photo of this question
plz give me your email id
i will send

[@DrMungli]

[e-mail]

[@mehakrubab2727]

Thnks professor

[@chamikaishara3778]

Thank you very much sir !! Understood those I couldn't workout by my own ❤

[@ricasaluria8821]

Is electrophoresis the reference method for the LIPOPROTEIN differenciation? Or ASSAY?

[@manaral-masri5054]

Sir, I read in a biochemistry reference that VLDL’s density ,which refers to proteins ratio, is less than LDL’s.. based on this information, isn’t LDL supposed to move faster than VLDL?

[@abdullahibrahim8938]

He already explained that, look from 3:55 to 4.40.

[@mbohhonorine8470]

Thank you Dr😊

[@DrMungli]

Ur welcome ☺️

[@ganeshchidambar3299]

Soo nice. Very simple language. Very easy to understand. Thank you Dr. Mungli

[@lostSempaiWissame]

Indian guy on TH-cam