CELL-MEDIATED response - A-level biology immunity cellular response of T cells (T Lymphocytes)
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- เผยแพร่เมื่อ 17 มิ.ย. 2024
- Learn the cell-mediated (cellular) response. This is the response linked to T lymphocytes. Learn how T-cells are activated and how the clonal selection results in activating B cells, stimulating phagocytes, cytotoxic T cells and memory cells.
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I am not even from AQA but this helped alot, thank you
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Thanks
You're welcome 😊
I thought that through maturation process, the T lymphocyte (having both CD8 +CD4) would differentiate into t helper and t cytotoxic via downregualtion of genes. does this happen after the t cell has been presented with the antigen? or is it that a t cell randomly produced with the correct receptor which has the highest bidnign affinity to the antigen gets clonally selected via APC and then differentiated into a cytotoxic t cell if needed? thanks for the video, your response will be much appreicated
Thumbs up after 3 minutes. Pls grant me permission to download this video.
So glad you found it helpful!!!
question - if b cells can also become antigen presenting cells when they encounter the antigen and take it in by endocytosis, what makes them different from phagocytes/macrophages that also become APC cells?thanks so much for the videos!
different antigens i think? they might just all be apc cells
Hey, I was just reading through Class Notes whilst also watching your videos. What's the difference between a cell-meditated response & a cellular response?
Or is it the same thing?
Btw what do you mean by embed on 5:27 ?
Hello, those two terms both mean the same thing :)
@@mohid0786
Hi, you might know by now but:
It can me attach (or fix) but for the sake of biology I'm gonna assume it's the former -attach.
Hi, do we need to know about macrophages and neurophils?
i don't think so as they got taken off the spec but it won't lose you marks if you do.
Do you have a video on binary fission?
Sorry I don't 😞
Does cell mediated immunity involve the MHC class 1 or two because I keep seeing different ones? Please help
cell-mediated involves MHC 2 where CD4 t helper cells bind onto the MHC2 complex of the APC such as the macrophage/dendritic cell. the MHC1 complex is only presented on those cells which are infected, which the Cytotoxic t cell binds onto and releases perforin destroying the cell by creating pores within the membrane which in turn reduces viral replication
May Allah bless you . Peace
Thank you!
Hi miss, what is the difference between a T lymphocyte and a T cell? Or are they meaning the same thing? & which shall I call it in the exam? Thanks
Their the same thing!
Sorry didn’t mean exclamation mark.
is this aqa?
yeah
Hi Miss,
When the cytotoxic T cells release perforin to create pores in the cell surface membrane and substances are able to leak in and out of the cell, would you consider this as an example of apoptosis. Apoptosis is controlled and tightly cell regulated death so would you say that this could be considered an example since the death of the infected cells is tightly controlled by the immune system and the Cytotoxic cells? However, if the pathogen was to destroy the cell this would be an example of necrosis but I was interested to see what you thought?
Hello,
As it is the body's response killing the cell, I would class it as apoptosis, not necrosis, as it isn't the pathogen directly causing the cell death.
Can some one explain how the vaccine affects the t Cells
vaccines are used to produce more antibodies essentially
1. vaccine contains antigen from pathogen
2. macrophage presents antigen on its surface and t cells simulate b cells
3. t cells with complementary receptor protein binds to the complementary antibody on its surface.
4. b cells secrete lots of antibodies
5. b cells divide to form clones secreting the same antibody to destroy the virus.