POIS Post Orgasmic Illness Syndrome or Adrenal fatigue? DHEA for POIS Post Orgasmic Illness Syndrome

Post Orgasmic Illness Syndrome POIS or Adrenal fatigue? DHEA for POIS Post Orgasmic Illness Syndrome Dr. Deepak Chaturvedi, MD drdeepakchaturvedi.com
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Post Orgasmic Illness Syndrome, POIS, POIS attacks, postejaculatory syndrome, post coital headache, post orgasm illness syndrome, post ejaculation sickness, post orgasmic sick syndrome, post orgasmic blues, post masturbation syndrome. Many names of the same problem. Post Orgasmic Illness Syndrome causes unbearable symptoms following orgasm. Post orgasmic Illness Syndrome was First documented in 2002 by Dr. Marcel Waldinger Ref: www.ncbi.nlm.nih.gov/pubmed/1... Symptoms last between up to a week following an orgasm. If orgasm occurs during this post orgasmic recovery period, the symptoms may prolong by another week to fully recover from orgasm with the rarely subsequent orgasm might alleviate the symptoms, However, Researchers believe that Post Orgasmic Illness Syndrome POIS is multi-factorial. It can be caused by multiple pathways. There are various theories - Immunologic theory, Neuro-Endocrine Theory, Endocrine Imbalance, Auto-Immunity, Atopy, Allergic response, Neurotransmitters, inflammation, etc. Based on my clinical experience I believe it's the Hormonal Imbalance affecting the inflammatory response, we have seen that NSAID's provide significant relief in patients and especially with Testosterone. However, prescribing Testosterone needs detailed evaluation. According to the hormone Synthesis pathway, DHEA is the precursor of Testosterone. DHEA in Post Orgasmic Illness Syndrome POIS is safe to supplement compared to Testosterone and can be given in small. DHEA in Post Orgasmic Illness Syndrome POIS can be given to both men and women. We don't have to forget that even women may have Post Coital Headaches, Post Orgasmic Illness Syndrome. Another reason to use DHEA in Post Orgasmic Illness Syndrome POIS is to look at the complaints of POIS Post Orgasmic Illness Syndrome closely and you will find that they resemble very closely to Adrenal Fatigue syndrome. They may range from Extreme mental fatigue, difficulty concentrating, difficulty in understanding or retaining short attention span, tired speech, foggy thinking, headache, anxiety, and depression to diarrhea, constipation, muscle pain, swathing, alternating hot or cold, physical fatigue, and restlessness. The symptoms of Adrenal Fatigue or Adrenal Exhaustion and Post Orgasmic Illness Syndrome POIS have some obvious overlap. So, if we start looking for symptoms of Adrenal Fatigue or Adrenal Exhaustion in patients and evaluate the Adrenal profile as well we can manage POIS in most of the case with the simple DHEA supplementation plus NSAID with or without Testosterone. Even if we look at the Immunogenic Pathogenesis theory. Research has shown that testosterone supplementation in hypogonadal males was found to suppress cytokines, a signal carrier that activates the immune system. (Which may otherwise be causing the symptoms and discomfort of POIS). The Effect of Testosterone Replacement on Endogenous Inflammatory Cytokines and Lipid Profiles in Hypogonadal Men. academic.oup.com/jcem/article... Low testosterone levels cause a slew of symptoms that are extremely similar to those of POIS. These include difficulty choosing words, physical fatigue, anxiety, depression, difficulty concentrating, and irritability. Several have reported having slightly low testosterone levels and could be potentially aggravating this condition via orgasm. link.springer.com/article/10.... Abnormally high levels of the two catecholamines, norepinephrine, and epinephrine, have been found to cause palpitations, insomnia, heightened blood pressure, feeling of uneasiness, heat, and sweating these also closely match those of Post Orgasmic Illness Syndrome POIS. Likewise, excess cortisol is known to aggravate the symptoms of Post Orgasmic Illness Syndrome POIS. This cortisol may surge during the sexual activity and then drop after orgasm thus compounding the effect of Adrenal Fatigue as well. However, on evaluation, the blood levels of cortisol may be High, Low or Normal. Interaction of Prolactin, Oxytocin, Dopamine, Catecholamines and Serotonin during sexual activity, arousal orgasm ejaculation or post orgasm are discussed.
Sex should not hurt.
Dr. Deepak Anjana V. Chaturvedi; M.B.B.S.; M.D.(Medicine)
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Internal Medicine, Metabolic Medicine Diabetes, Thyroid, Obesity, Antiaging & Geriatric Consultant. Antiaging Hormones Physician. Wellness & Lifestyle Consultant. Motivational Speaker.
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Amaaya Clinic, 704, Aston Building, Sundervan Complex, Andheri (w), Mumbai, 400053
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