What drives evolution | Denis Noble | Reason with Science | Darwin | Selfish genes | Richard Dawkins

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  • เผยแพร่เมื่อ 14 พ.ค. 2024
  • This episode is with Denis Noble.
    He is a renowned biologist, physiologist, and systems theorist, known for his pioneering research in the fields of cardiac physiology and systems biology.
    Noble's early work on the electrical activity of the heart was centered on this topic, and he was the first to put forth the notion of the cardiac action potential, which is now generally recognized in the field. He has also contributed significantly to our understanding of cardiac arrhythmias, irregular heart rhythms that can cause serious health concerns.
    In addition to his work in cardiac physiology, Noble has been a critical player in the development of systems biology, which aims to comprehend complex biological systems by integrating data from different sources. He has also been a vocal proponent of using mathematical and computational approaches in biology, and his work has contributed to developing a new paradigm for biological research.
    In this conversation we talk about the topics related to evolution, including Neo-Darwinism, the role of DNA as information, the use of genes as templates for evolution, the emerging field of epigenetics, the significance of bioelectricity, and potential future directions for evolutionary research.
    Guest info:
    Website: www.dpag.ox.ac.uk/team/denis-...
    Google scholar: scholar.google.com/citations?...
    Amazon: www.amazon.com/Books-Denis-No...
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    Timestamps:
    00:00:00 Introduction
    00:00:58 DNA as the information in biological systems
    00:20:30 What drives evolution?
    01:00:49 Horizontal gene transfer
    01:05:03 What is an organism?
    01:23:08 Importance of metaphors
    01:31:00 What is a gene?
    01:31:57 Evolution of species
    01:39:03 Artificial life
    01:41:04 Thank you!
    More on Reason with Science:
    1) Chemistry of life and death | Nick Lane | Reason with Science | Origin of life | Biochemistry ( • Chemistry of life and ... )
    2) Collective intelligence of cells | Michael Levin | Reason with science | Bioelectricity | Biology ( • Collective intelligenc... )
    3) Powering the complexity of life with Michael Levin and Nick Lane | Reason with Science | Biology ( • Powering the complexit... )
    4) How multicellularity evolves | William Ratcliff | Reason with Science | Origin and evolution of life ( • How multicellularity e... )
    5) The evolutionary origins of a good society | Nicholas Christakis | Reason with Science | Psychology ( • The evolutionary origi... )
    More talks/conversations of Denis:
    1) Richard Dawkins and long-time rival Denis Noble go head to head on the selfish gene | Who is right? ( • Richard Dawkins and lo... ) @TheInstituteOfArtAndIdeas
    2) Prof Denis Noble - Dance to the Tune of Life Lecture ( • Prof Denis Noble - Dan... ) @voicesfromoxfordUK
    3) Can chemistry solve the origin of life? Perry Marshall, Denis Noble and Lee Cronin ( • Can chemistry solve th... ) @PremierUnbelievable
    #reasonwithscience #evolution #biology
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ความคิดเห็น • 33

  • @Mousey316
    @Mousey316 ปีที่แล้ว +12

    great interview. noble is very knowledgeable and articulate. i applaud the interviewer for giving him the time to develop his thoughts without interruption. well done.

  • @syedalishanzaidi1
    @syedalishanzaidi1 10 หลายเดือนก่อน +8

    Whether Prof Denis Noble is proved right or not, what should be applauded here is the fact that he is corageous enough to voice his thoughts in order to provoke the attention of the scientific community in this direction. Like Dawkins himself, he is a great explainer of ideas, and it is amazing how his train of thoughts never wanders, but stays true to the course. Where this kind of thinking in the field of evolutionary biology will lead in the end is difficult to predict. There is a lot going on in the processes which define or determine what life is, and how it came about to begin with. Jim Al Khalili has i think tried to draw the attention of science to what may be happening deep inside living cells, and he points to the intricacies of Quantum mechanics as perhaps having an effect in the way particles inside cells behave. Whether it is specialists in evolutionary biology, or the lay public which takes an interest in these matters, we should welcome the trends in thinking which seem to be bekoning towards as yet untravelled paths. Darwin I think would be with us all the way.
    And I have to say that I loved the way Jitender Kumar listened without interrupting. Full marks to him for keeping his peace, and never wavering in his attention to what the eminent Prof was saying. Many thanks to them both.

  • @bertrandthebault6899
    @bertrandthebault6899 9 หลายเดือนก่อน +2

    Denys Noble is a star

  • @hn6187
    @hn6187 หลายเดือนก่อน

    Genes are the piano keys we play... To explore the possibilities of music ... To paraphrase Prof Noble. The science of the Metaphysics of panpsychism

  • @hn6187
    @hn6187 หลายเดือนก่อน

    I love how prof noble references his speech to show how science is above language and borders, a supra culture unto itself, inspired mostly by its own careful recursion, and art

  • @ferrantepallas
    @ferrantepallas 10 หลายเดือนก่อน +2

    brilliant and fascinating presentation, thank you

  • @Spudmay
    @Spudmay 10 หลายเดือนก่อน +1

    This is a very wonderfully interesting concept. Now I have to investigate this further. It seems weird I haven't heard of this at all (I am also very very new to ingesting science).

  • @hn6187
    @hn6187 หลายเดือนก่อน

    Prof noble is right to point out his debt to neo Darwinists, their extreme position provides the fodder for his Scepticism, and so vice versa. By positing top down causation is not possible we can then frame hypotheses to attempt to disprove this. So a more nuanced set of models that describe life can emerge

  • @phil3.146
    @phil3.146 11 หลายเดือนก่อน +2

    Good interview.

  • @rustycalvera977
    @rustycalvera977 10 หลายเดือนก่อน +1

    what an interesting discussion this is....how beautifully put forth by denis noble.

  • @alexnewton7484
    @alexnewton7484 9 หลายเดือนก่อน

    Wonderful interview. Our environment/habits determining our evolution is the single most important piece of knowledge in the world today. The obesity epidemic, myopia epidemic, dental occlusion epidemic, and mental health epidemic are all being driven through environment and passed on to future generations via these transgenerational effects. If you aren't convinced by Noble, look up "Dias and Ressler 2014"

  • @patod4
    @patod4 8 หลายเดือนก่อน +1

    Not yet listened to all of it. But why isn't Lamarck mentioned, after all he supported what today we call somatic inheritance, am I wrong?

    • @bastiaanschouwink3562
      @bastiaanschouwink3562 8 หลายเดือนก่อน +1

      the weissman barrier is the same as anti neolamarckism, i believe. noble is i think a lamarckist

  • @lokeshparihar7672
    @lokeshparihar7672 6 หลายเดือนก่อน

    21:30 julian huxley book

  • @keaton718
    @keaton718 7 หลายเดือนก่อน

    Humble looking home. You’d think a household name like Denis, in biologist households anyway, he’d have a grand home. In movies famous biologists are rich.

    • @hn6187
      @hn6187 หลายเดือนก่อน

      Value creators don't get rich ££££££, that's not what money is. the people who Own their ideas with accountancy grifts do... Do you see what money is? Indeed Noble can thank his lucky stars his fate wasn't that of Turing Socrates Spinoza Nietzsche ... "Ownership" / appropriation is of course violence on a scale. As a Brit I'm particularly ashamed of what the British police did to Turing our greatest war hero and innovator

  • @JungleJargon
    @JungleJargon 10 วันที่ผ่านมา

    Imagination drives evolution along with speculation conjecture assumption assertion and irrational fantasy.

  • @gemishedinterviews
    @gemishedinterviews ปีที่แล้ว +1

    I wonder if Mr. Noble knew my Grandpa, R. Schwyzer. He reminds me of the way he spoke to me when I was young.

  • @keaton718
    @keaton718 7 หลายเดือนก่อน

    I still think Denis is reaching here. But that he’s got a sense of something that is actually going on. But it’s not quite what he says it is.

  • @nancymatro8029
    @nancymatro8029 หลายเดือนก่อน

    Noble seems to suggest that every organelle has its own DNA which is passed on to it's offspring. How this is accomplished he doesn't say. I can't find anyone else who corroborates this point of view.

  • @tomato12terra
    @tomato12terra 11 หลายเดือนก่อน

    hmmm, is Noble advocating directionality of selecting and evolution? Does not convince me

    • @Iwansidi
      @Iwansidi 11 หลายเดือนก่อน

      Me neither...I am even a little annoyed that he is running victory laps as if the case was already settled. The condescending way in which he talks about the "writer" Dawkins is actually embarrassing.

    • @tomato12terra
      @tomato12terra 11 หลายเดือนก่อน

      @@Iwansidi yes, and without providing any evidenced alternative to the self replicator as unit of selection

    • @willsimp1273
      @willsimp1273 10 หลายเดือนก่อน

      Clearly you 2 kids don’t understand anything about what he is talking about and should stay silent and finish school

    • @vikkumar9301
      @vikkumar9301 10 หลายเดือนก่อน +3

      @@tomato12terra I thought he did provide a lot of evidences.

    • @alexnewton7484
      @alexnewton7484 9 หลายเดือนก่อน +4

      He provided plenty of evidence, both here and in his debate with Dawkins. If you'd like more, look up "Dias and Ressler 2014."

  • @wulphstein
    @wulphstein 11 วันที่ผ่านมา

    What drives evolution? Bad math.