Thanks for watching this episode with Dr. Nadir Ali! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙
I call utter nonsense on plants being chemical warfare entities. Animals eat plants. Hello?!? Is anyone hone? Animal flesh is biologically processed and concentrated plant matter. There is symbiosis in the food chain, not animosity. Well, until humans denutrify the soil, the plant and then add all sorts of toxins, that is.
Dr. Nadir Ali is absolutely the best on CVD. There are many doctors who are shedding light on the false cholesterol hypothesis, statins, heart disease and muddled dietary guidelines, but I have learned more from him than anyone else. (I need to cut my daily avocado down from the current 1/3, and reduce the amount of olive oil from 2 tbsps and increase the butter and ghee) Thanks, Jesse, great interview, very thoughtful questions that drew interesting insights.
Dr Nadir is one of my personal heroes 🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸 I agree there is not one diet for everyone…rather, diet should be individualized. Also agree we need much more research on all of this! Thanks Jesse - great discussion
Yes, but we have lots of people doing their own n=1 experiments. I'd say the collection of all those experiments can provide some very compelling evidence!
a Great episode and I never get enough of listening to Dr. Nadir Ali. Always information and well presented on how our digestion works and how cholesterol is so needed for the body. I just started a Carnivore challenge and already my brain works better. I can see now that the fiber that is blocking cholesterol and nutrients from being absorbed finally hits home.
Dr Ali is correct. Someone who is not metabolically healthy eating high fat can develop lipotoxicity. Too much glucose or too much fats consumed is both not good. Bart Kay explains this well in his Randal cycle presentations. Both fuel substrates can overwhelm the cell can lead to insulin resistance or high triglycerides
Just some anecdotal experience here. I suffered with such major heartburn/GERD that I considered Tums part of my daily food pyramid, and also took Nexium. Despite this, I sometimes had to supplement with baking soda. Last September, I went on a low carb diet, stopped eating bread, cookies, etc., and the symptoms disappeared -immediately and completely. Just saying.
I like Dr. Ali' s perspective on proper diet generally, especially the idea that one size doesn't fit all!. I have nothing against carnivore diet and if it solves health problems, i would certainly recommend or even follow, but it's not for everyone. About 7 months now I have been on a low carb diet. I was already a meat eater, so it was just cutting out sugars, refined foods and other carbs. I have lost 30 lbs since then. I am at the lowest end of my BMI and i do eat , some days, maybe 120 g of carbs. mostly above ground, low carb veggies, but most days its below 100g.
Wow, we only sous vide our steaks for 2 hours! It is still very tender. We use silicone sous vide bags to avoid the BPAs and phthalates. Since these bags arent vacuum sealed, sous vide magnets help keep the bags from floating around.
The discussion of plant sterols is very interesting. I've been watching Dr. Paul Mason recently and he implicates plant sterols in the formation of blood clots that cause arteriosclerosis.
Hardening of the arteries is from lack of d3 and k2 absorption that heals the arteries with calcium that is going into the arterial scarred tissues instead of into the bones.
Hi, thanks for the information. I did notice an immediate improvement in my ibs when I cut out sugar and bread, had meat (beef, lamb) and some vegetables. But I read Chris Wark's book and he beat his colon cancer eating fruit and veg after an operation and zero chemo. He looks very healthy, do I am curious about whether there's something that's missing in both carnivore and vegetarian research and how our body works and reacts.
I respect his view on metabolic individuals not starting out on high fat and high protein... I would also suggest what others have offered, and that is for those individuals to first eat the fat until it no longer tastes good and then start on the protein of the meat until it no longer tastes good. There is a definite stop when eating fat by itself. It is much much harder for the body to know how much fat to consume in a meal when eating it with the protein meat portion. One can easily experiment with this. I am naturally very lean so I have no experience with an overweight stuffed fat cell body to comment on whether or not their tastes would also respond to this way of eating fat first.
Thank you both for this wealth of information! As a lifelong hypoglycemic addicted to carbs, now fat adapted 62 year old, I’ve trained myself to fast without discomfort for up to 3-4 days. I’ve learned fat metabolism works best in context of fasting and occasional carbohydrate cycling.Ill try reducing fat intake now that I have healed decades of gallbladder issues. Also will try weaning myself off hydrochloric acid a bit.
I cured my A-fib by greatly reducing the oxalates in my diet! I was eating copious amounts of oxalate containing super foods for 3.5 decades. Theses oxalates locked up my calcium, magnesium and potassium which are the minerals that regulate the electrical signal to the heart. When i started tracking and reducing my oxalate intake all my arrhythmia issues went away!! Dr Ali is awesome!!
The vitamin C argument is so interesting. People always seem to argue as if somehow nature made a mistake by stopping human beings making their own vitamin C. (As well as some other other animals.) In fact, there may be longevity and health advantages. If you look into the biochemistry of the production of endogenous vitamin C there are some quite serious downsides. 1. **Metabolic Cost**: The synthesis of vitamin C requires energy and resources. The pathway involves multiple enzymatic reactions, which consume substrates and energy that could be used for other metabolic processes. 2. **Oxidative Stress**: The production of vitamin C can generate reactive oxygen species (ROS) as by-products, especially during the conversion of L-gulonolactone to ascorbic acid. These ROS need to be managed by the cell's antioxidant defenses to prevent damage. 3. **Enzyme Efficiency**: The efficiency of the enzymes involved in the pathway can vary. If the enzymes are not highly efficient, the organism might need to produce them in larger quantities to meet its vitamin C needs, which could be an additional metabolic burden. 4. **Regulatory Complexity**: The regulation of the vitamin C synthesis pathway must be finely tuned to balance production with the organism's needs. Overproduction of vitamin C can lead to unnecessary energy expenditure, while underproduction can lead to deficiency. 5. **Evolutionary Trade-offs**: In species that have lost the ability to synthesize vitamin C, such as humans, guinea pigs, and some primates, it is believed that the evolutionary trade-off may have provided some other advantage or simply that the loss was neutral in the context of their diet. Relying on dietary sources of vitamin C could have been less costly than maintaining the synthetic pathway.
I agree about not eating too much fat. I have been doing the meat and fat diet. But the weight wont budge. I was 4 days into a 5 day fast. My friend invites me over to help her fill in forms. She tempted me with scones and jam and cream. It was stressful filling in the form as she made a 30 min job into a 4 hour job. Then she produced cake muffins toasties. Well it was fast went fast out the window. I have not done a fast now for months. And my weight even on Carnivore is not going down.
I love this beautiful doctor and Jesse what a great interview! I was called a troll when a certain young lady 1:19:20 steak and butter influencer shows how she eats a stick of butter a day and a bunch of meat a day steak for that matter, and I commented to her post that she was a bad influence to certain people that cannot eat like that she made it sound like everybody should eat like that and it’s not true as Dr. Nadir is explaining here.
But how many are truly metabolically healthy? Many think they are healthy because they don't feel anything ... yet. I think the majority of the population, who have been eating a 'normal' diet, are not metabolically healthy.
So do we have a double advantage over animal carnivores, in that we also have more acidic stomachs than they do (or was the purpose of that to allow us to be able to handle meat that is not as fresh?)? Or are you saying that we need the higher acidity in our stomachs to ensure that what enters the small intestines is more germ free, due to their better absorption capability (so sort of a different trade-off than made by the evolutionary tract that typical carnivores followed)? By the way, Dr. Ali, I am very impressed with the depth of knowledge you have of the science behind nutrition!
So I must be 9 months into carnivore using eggs and lots of cheese to try and sustain weight. I went carnivore with the feeling that I was metabolicaly unhealthy although my bmi is within range. I feel at times eating this way my blood pressure rises... could this be due to high triglycerides combined with high fat?
I wouldn't assume all older people have depleted stomach acid... due to the widespread over use of antacids, many older people have poor stomach acid, but not all older adults
I don't understand what is ' zone 2 ' exercises. How does it look in practise? Is it light cardio, or some kind of HIIT, or short slow workouts with weights, or just walking?
Zone 2 is a specific heart rate range. Example would be 127-140 beats per minute. Doing an exercise that would keep your heart rate in this range, like running, cycling, maybe circuit training(depending on individual). For me zone 2 is definitely running. HIIT would have the heart rate way higher than zone 2 and walking is zone 1. Hope this helps. There are heart rate zone calculators online or if you wear a fitness watch, this will usually be calculated somewhere in your profile.
Walking leisurely over an extended period of time for example is zone 1. Running, rowing, doing crosstrainer at a miximum of 60-70 % of your miximum heart rate over an extended period of time is zone 2 training.
Thankyou Dr Ali for having the good sense to explain (12:00) why SOME plant food is fine for most humans who also eat meat and fish. And that we humans are Omnivores.
That’s not what he said. He said we don’t know enough yet, and that some people should absolutely *not* eat plants. It’s case by case. We have to hear what’s said not what we want to hear
@@truthtelleranon Yes, you’re right. He said “The human digestion is designed not to be a complete carnivore, but there are options of being an Omnivore also…etc”.
For someone who has Gilbert’s syndrome. Fasting and eating only two or less meals per day doesn’t work. Liver can’t handle the fat load. Have to eat about 4-6 small meals to avoid feeling awful.
I'm sorry but I disagree with the cooking time to sous vide steaks. Unless it's a ribeye roast it shouldn't cook any longer than 2 to 4 hours. Six hours to overnight is way too long. You might as well cook the steak in a crockpot. Another way is to reverse sear your steaks. I cook steaks in a low temperature oven, 210F for about 50 minutes turning it halfway through. Then I will heat up a cast iron pan about medium high (6 on electric range). Sear the steaks on all sides for about 30 seconds each side. You can also sear the steak on a grill. Throw the steak on a plate top it with some butter and salt. Done. A faster method is to start with a cold pan, I use cast iron, place the steak in it, turn the heat up to high (8) or so, flip the steak every 2 minutes for about 10 - 15 minutes depending on the doneness you like. You can use a meat thermometer to test it. That's it, in less than 20 minutes you have a juicy yummy steak.
Thanks for watching this episode with Dr. Nadir Ali! If you're finding it valuable, please vote by hitting the LIKE button on the video. This lets me know what type of guests to book for upcoming shows. Thanks! -Jesse 💙
I call utter nonsense on plants being chemical warfare entities.
Animals eat plants. Hello?!? Is anyone hone? Animal flesh is biologically processed and concentrated plant matter.
There is symbiosis in the food chain, not animosity.
Well, until humans denutrify the soil, the plant and then add all sorts of toxins, that is.
Jesse you are the best interviewer in The health space by far.
Thank you! 💙
Dr. Nadir Ali is one of the best cardiologist❤🫶💪🧠👍
Dr. Nadir Ali is absolutely the best on CVD. There are many doctors who are shedding light on the false cholesterol hypothesis, statins, heart disease and muddled dietary guidelines, but I have learned more from him than anyone else. (I need to cut my daily avocado down from the current 1/3, and reduce the amount of olive oil from 2 tbsps and increase the butter and ghee)
Thanks, Jesse, great interview, very thoughtful questions that drew interesting insights.
Much needed topic, people need to understand how vegetable/seed oil is destroying their body! Thank you!
Dr Nadir is one of my personal heroes 🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸🇺🇸
I agree there is not one diet for everyone…rather, diet should be individualized.
Also agree we need much more research on all of this!
Thanks Jesse - great discussion
Yes, but we have lots of people doing their own n=1 experiments. I'd say the collection of all those experiments can provide some very compelling evidence!
Thanks for your great content and bringing us these great guest. I've been following Dr. Ali for quite some time.
This is one of my first pioneers in reclaiming my health. Huge fan of Dr. Ali. And to top it off, he's an avid cyclist
a Great episode and I never get enough of listening to Dr. Nadir Ali. Always information and well presented on how our digestion works and how cholesterol is so needed for the body. I just started a Carnivore challenge and already my brain works better. I can see now that the fiber that is blocking cholesterol and nutrients from being absorbed finally hits home.
another great episode..you two compliment each other.when i don't understand what the Doc is saying i just wait for Jesse to clear it up
Thank you 🙌
Thank you Jess!
Dr Ali is correct. Someone who is not metabolically healthy eating high fat can develop lipotoxicity. Too much glucose or too much fats consumed is both not good. Bart Kay explains this well in his Randal cycle presentations. Both fuel substrates can overwhelm the cell can lead to insulin resistance or high triglycerides
Can you help me to find that video of Bart, I’d like to watch that.
Just some anecdotal experience here. I suffered with such major heartburn/GERD that I considered Tums part of my daily food pyramid, and also took Nexium. Despite this, I sometimes had to supplement with baking soda.
Last September, I went on a low carb diet, stopped eating bread, cookies, etc., and the symptoms disappeared -immediately and completely. Just saying.
That same result happens frequently to many other people!
Same happened to me
Ditto!
@@suewestby824
Excellent!
Me too. No migraine and asthma either. Autoimmune Sjogrens almost asymptomatic despite positive antibodies. Brain fog gone, sleep pattern better.
Jesse is the interviewer who tends to ask the most interesting and wide-ranging questions within this food/health universe! Good job young man!!
Thank you! 💙
Wow! lots of information, and I feel so lucky to hear from Dr. Ali for 2 hours!!! thank you!
Your questions and follow up on answers is top level!! Great interview!
I like Dr. Ali' s perspective on proper diet generally, especially the idea that one size doesn't fit all!. I have nothing against carnivore diet and if it solves health problems, i would certainly recommend or even follow, but it's not for everyone. About 7 months now I have been on a low carb diet. I was already a meat eater, so it was just cutting out sugars, refined foods and other carbs. I have lost 30 lbs since then. I am at the lowest end of my BMI and i do eat , some days, maybe 120 g of carbs. mostly above ground, low carb veggies, but most days its below 100g.
As long as you're doing and feeling good. Age is also a big factor!
Such an excellent interview, excellent questions and excellent answers by Dr Nadir Ali.
Thanks 🙌🏻
I love Dr. Ali's balanced view.
Great podcast, after I heard " we cannot ignore to look at the individual person, diet has to be individualize" 100% in agreement. Jesse, you rock!
So much information.. thank you both. 🙏
Wow, we only sous vide our steaks for 2 hours! It is still very tender. We use silicone sous vide bags to avoid the BPAs and phthalates. Since these bags arent vacuum sealed, sous vide magnets help keep the bags from floating around.
The discussion of plant sterols is very interesting. I've been watching Dr. Paul Mason recently and he implicates plant sterols in the formation of blood clots that cause arteriosclerosis.
Hardening of the arteries is from lack of d3 and k2 absorption that heals the arteries with calcium that is going into the arterial scarred tissues instead of into the bones.
Thanks a lot for this fantastic episode.
Very interesting our bodys are incredible , exercise. THANKS!😊
Wow dr Ali again knocking out of park, what a follow up episode 🙌👊🙏
Thanks so much, he's the best! I think the two chats together are a powerful combo!
@@JesseChappus first it takes a great host, u brought out his best, thanks for being so good at ur job, keep em coming we love u Jesse!
🙌💙
Jesse you are The best host Please get Senada Greca as your guest There’s lots to learn from her
Hi, thanks for the information. I did notice an immediate improvement in my ibs when I cut out sugar and bread, had meat (beef, lamb) and some vegetables. But I read Chris Wark's book and he beat his colon cancer eating fruit and veg after an operation and zero chemo. He looks very healthy, do I am curious about whether there's something that's missing in both carnivore and vegetarian research and how our body works and reacts.
And I feel Dr Nadir Ali is the kind who will re evaluate and question rather than arrogantly brush off anything that does not fit his narrative.
I respect his view on metabolic individuals not starting out on high fat and high protein... I would also suggest what others have offered, and that is for those individuals to first eat the fat until it no longer tastes good and then start on the protein of the meat until it no longer tastes good. There is a definite stop when eating fat by itself. It is much much harder for the body to know how much fat to consume in a meal when eating it with the protein meat portion. One can easily experiment with this.
I am naturally very lean so I have no experience with an overweight stuffed fat cell body to comment on whether or not their tastes would also respond to this way of eating fat first.
I value Dr Nadir opinion 💙💙
Jesse,
Another absolutely fantastic interview!!!!
I'll be listening to this several times.
Thank you !!!
Very informative video! Thanks
Thank you both for this wealth of information! As a lifelong hypoglycemic addicted to carbs, now fat adapted 62 year old, I’ve trained myself to fast without discomfort for up to 3-4 days. I’ve learned fat metabolism works best in context of fasting and occasional carbohydrate cycling.Ill try reducing fat intake now that I have healed decades of gallbladder issues. Also will try weaning myself off hydrochloric acid a bit.
I cured my A-fib by greatly reducing the oxalates in my diet! I was eating copious amounts of oxalate containing super foods for 3.5 decades. Theses oxalates locked up my calcium, magnesium and potassium which are the minerals that regulate the electrical signal to the heart. When i started tracking and reducing my oxalate intake all my arrhythmia issues went away!!
Dr Ali is awesome!!
The vitamin C argument is so interesting.
People always seem to argue as if somehow nature made a mistake by stopping human beings making their own vitamin C. (As well as some other other animals.)
In fact, there may be longevity and health advantages.
If you look into the biochemistry of the production of endogenous vitamin C there are some quite serious downsides.
1. **Metabolic Cost**: The synthesis of vitamin C requires energy and resources. The pathway involves multiple enzymatic reactions, which consume substrates and energy that could be used for other metabolic processes.
2. **Oxidative Stress**: The production of vitamin C can generate reactive oxygen species (ROS) as by-products, especially during the conversion of L-gulonolactone to ascorbic acid. These ROS need to be managed by the cell's antioxidant defenses to prevent damage.
3. **Enzyme Efficiency**: The efficiency of the enzymes involved in the pathway can vary. If the enzymes are not highly efficient, the organism might need to produce them in larger quantities to meet its vitamin C needs, which could be an additional metabolic burden.
4. **Regulatory Complexity**: The regulation of the vitamin C synthesis pathway must be finely tuned to balance production with the organism's needs. Overproduction of vitamin C can lead to unnecessary energy expenditure, while underproduction can lead to deficiency.
5. **Evolutionary Trade-offs**: In species that have lost the ability to synthesize vitamin C, such as humans, guinea pigs, and some primates, it is believed that the evolutionary trade-off may have provided some other advantage or simply that the loss was neutral in the context of their diet. Relying on dietary sources of vitamin C could have been less costly than maintaining the synthetic pathway.
I agree about not eating too much fat.
I have been doing the meat and fat diet. But the weight wont budge.
I was 4 days into a 5 day fast. My friend invites me over to help her fill in forms.
She tempted me with scones and jam and cream.
It was stressful filling in the form as she made a 30 min job into a 4 hour job.
Then she produced cake muffins toasties.
Well it was fast went fast out the window.
I have not done a fast now for months. And my weight even on Carnivore is not going down.
Thank you very much. GREAT interview… GREAT guest…GREAT questions Jesse! ❤️👏👏👏
Thanks a ton! :)
I love this beautiful doctor and Jesse what a great interview! I was called a troll when a certain young lady 1:19:20 steak and butter influencer shows how she eats a stick of butter a day and a bunch of meat a day steak for that matter, and I commented to her post that she was a bad influence to certain people that cannot eat like that she made it sound like everybody should eat like that and it’s not true as Dr. Nadir is explaining here.
But how many are truly metabolically healthy? Many think they are healthy because they don't feel anything ... yet. I think the majority of the population, who have been eating a 'normal' diet, are not metabolically healthy.
So so true!
He is so great, i found myself fall in love with him
So do we have a double advantage over animal carnivores, in that we also have more acidic stomachs than they do (or was the purpose of that to allow us to be able to handle meat that is not as fresh?)? Or are you saying that we need the higher acidity in our stomachs to ensure that what enters the small intestines is more germ free, due to their better absorption capability (so sort of a different trade-off than made by the evolutionary tract that typical carnivores followed)? By the way, Dr. Ali, I am very impressed with the depth of knowledge you have of the science behind nutrition!
He absolutely needs to clarify the HCTZ versus hydrochloric acid state
Hi
If you can get talks about oral microbiome
I am a dentist by profession but very much interested in learning in the whole body wellness
Thanks
So I must be 9 months into carnivore using eggs and lots of cheese to try and sustain weight. I went carnivore with the feeling that I was metabolicaly unhealthy although my bmi is within range. I feel at times eating this way my blood pressure rises... could this be due to high triglycerides combined with high fat?
I wouldn't assume all older people have depleted stomach acid... due to the widespread over use of antacids, many older people have poor stomach acid, but not all older adults
Digestive enzymes work brilliantly especially if you are burping after meals take a couple just before eating and you will notice the burping stopping
I don't understand what is ' zone 2 ' exercises. How does it look in practise? Is it light cardio, or some kind of HIIT, or short slow workouts with weights, or just walking?
Zone 2 is a specific heart rate range. Example would be 127-140 beats per minute. Doing an exercise that would keep your heart rate in this range, like running, cycling, maybe circuit training(depending on individual). For me zone 2 is definitely running. HIIT would have the heart rate way higher than zone 2 and walking is zone 1. Hope this helps. There are heart rate zone calculators online or if you wear a fitness watch, this will usually be calculated somewhere in your profile.
@@kylewtslaunwhite ok, thank you very much. ♥️🌹
Walking leisurely over an extended period of time for example is zone 1.
Running, rowing, doing crosstrainer at a miximum of 60-70 % of your miximum heart rate over an extended period of time is zone 2 training.
@@jaghad ok, thanks.
Thankyou Dr Ali for having the good sense to explain (12:00) why SOME plant food is fine for most humans who also eat meat and fish. And that we humans are Omnivores.
That’s not what he said. He said we don’t know enough yet, and that some people should absolutely *not* eat plants. It’s case by case. We have to hear what’s said not what we want to hear
@@truthtelleranon Yes, you’re right. He said “The human digestion is designed not to be a complete carnivore, but there are options of being an Omnivore also…etc”.
What are good carbs?
Complex Carbs... like leafy greens.
Can we get all the nutrients and minerals from Spirulina and Chlorella, along with eating meat
No, study more
Dear Jesse I want to talk with you from India how can I talk with you....
For someone who has Gilbert’s syndrome. Fasting and eating only two or less meals per day doesn’t work. Liver can’t handle the fat load. Have to eat about 4-6 small meals to avoid feeling awful.
I'm sorry but I disagree with the cooking time to sous vide steaks. Unless it's a ribeye roast it shouldn't cook any longer than 2 to 4 hours. Six hours to overnight is way too long. You might as well cook the steak in a crockpot. Another way is to reverse sear your steaks. I cook steaks in a low temperature oven, 210F for about 50 minutes turning it halfway through. Then I will heat up a cast iron pan about medium high (6 on electric range). Sear the steaks on all sides for about 30 seconds each side. You can also sear the steak on a grill. Throw the steak on a plate top it with some butter and salt. Done. A faster method is to start with a cold pan, I use cast iron, place the steak in it, turn the heat up to high (8) or so, flip the steak every 2 minutes for about 10 - 15 minutes depending on the doneness you like. You can use a meat thermometer to test it. That's it, in less than 20 minutes you have a juicy yummy steak.
Like and share
How long is low-fat how many grams of fat?
How low how many grams of fat is low fat
Please confirm if this guy is on the meat industry's payroll.
You look fit. Are you vegan? Lol.
Did Dr Ali say 4 or 40% of canola can be trans fats?
Close to 4% :)
@@JesseChappus Thanks - kept replaying but couldn’t catch it!
I was poised to type how poor this fellow is, (first part is very amateurish), but he got better. Glad I persevered. Avocados, Olive oil….😊
experts: don't fast but here have some ozempic 🤣🤣🤣🤣
Ozempic is a medicinal fasting. It forces the body into a fasting state. Dangerous for people with lack of self control.
All opposing sides have logic sounding points. This is not helping. Guess I'll stay in the middle.
What is an optimal diet for humans? Idk. But more air intake is probably part of it.
Cooking my steak in a plastic bag doesn't sit well with me