Genetic mutation | gene mutation

Genetic mutation in humans explained. This lecture explains about gene mutation and chromosomal mutation in animals. gene mutations and genetic mutations are dangerous and the effect is horrifying.
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A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most humans. Mutations variety in dimension; they are able to have an impact on wherever from a single DNA building block (base pair) to a huge segment of a chromosome that involves more than one genes.
Gene mutations can be classified in two most important approaches:
Hereditary mutations are inherited from a mother or father and are present for the period of a individual’s lifestyles in practically each mobile within the body. These mutations are also referred to as germline mutations due to the fact they're present within the mum or dad’s egg or sperm cells, which might be also called germ cells. When an egg and a sperm mobilephone unite, the resulting fertilized egg telephone receives DNA from both mum and dad. If this DNA has a mutation, the youngster that grows from the fertilized egg may have the mutation in every of his or her cells.
Acquired (or somatic) mutations arise at some time during a character’s lifestyles and are present handiest in specified cells, not in each telephone within the physique. These changes can also be induced by using environmental explanations corresponding to ultraviolet radiation from the solar, or can occur if a mistake is made as DNA copies itself for the period of telephone division. Acquired mutations in somatic cells (cells rather then sperm and egg cells) can't be passed on to the next iteration.
Genetic changes that are described as de novo (new) mutations can be either hereditary or somatic. In some cases, the mutation occurs in a man or woman’s egg or sperm mobile but isn't present in any of the character’s other cells. In other instances, the mutation happens in the fertilized egg quickly after the egg and sperm cells unite. (it's commonly unimaginable to tell exactly when a de novo mutation happened.) because the fertilized egg divides, each and every resulting phone within the developing embryo could have the mutation. De novo mutations could provide an explanation for genetic issues wherein an affected child has a mutation in each mobilephone in the physique however the mum and dad don't, and there is not any loved ones historical past of the sickness.

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[@5y3d_mu5h4h3d]

The term mutation refers to a permanent change in the genetic material or nucleotide sequence of a gene giving rise to a new genetic trait or genotype

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Please explain the mechanism of transition and transversion mutation

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[@manishaggarwal6729]

Sir u said at 2:08 " That many mutations are there where phenotypic change is not reflected by gene change " , sir is this statement same as to that " many mutations are there where gene change is not reflected by the phenotypic change " or u wanted to say second latter statement ????

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Sir please make video of this topic in hindi i.e Mutation and it's type

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[@lissadipity]

Hi everyone ! I know this may be sort of off topic but I am a 27 yo female and I have Essential Thrombocythemia with the “SF1” gene mutation/myeloid malignancy (48.5% proliferation). Is there anyone here that is familiar with SF1 and can possibly explain ? I am finding very little information on the mutation. I was diagnosed with a platelet count of 1.4 million and I am intolerant of oral platelet reducing drugs and interferon has negatively affected my thyroid function. I am seeking some answers. If any of you may have some insight, please feel free to respond ! ✊🏽

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Okay

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Sir,
Why mutation is helpful in secondary metabolite so plz tell me the reason

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is there any video regarding crossing over in detail?

[@gurkiratsingh0801]

Can we say this the generic mutation is major role player in evolution of human race or kind.?

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What's the difference between gene and genetic? ?

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thank you sir..

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THANK U

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[@iluvbeef11]

hi shomu. I have a question about the point additions that cause frame shifts. so when you added that A to the sequence, does the complementary DNA strand also get an addition (i.e. an additional T)? or is it just the one strand that gets mutated? thanks!

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Dada tumi khub vlo porou

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Thank you

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Some of the chenal make very long video
that make me feel scary to learn. But this video is great

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Sir there is question in the book.. Is it possible to say when a gene will mutate?

[@bridgetfhelm]

Usually during formation in the womb when it’s a genetic mutation. You are born with it. But the “symptoms” don’t always appear until later in life. My husband and daughter have a rare genetic mutation where at a splice site there is a T where there should be a G. Only my husband has mild symptoms of the mutation so far. Nothing anyone would notice - just a few small skin tags.

[@rahamatkhan3619]

Sir one question ...why microbial mutation is necessary for formentation process

[@dr.parasdayma8432]

Hello Sir
Can You please upload a video explaining the mechanism of UV rays on DNA. Tell me which of the UV wavelength is suitable to cause mutation in bacterial DNA. What is the Difference in absorption using 260 and 365 nm?

[@istiakrana8969]

Cutie 💞

[@pandapanda6341]

Can you please tell me how does the ph effect on mutations.

[@naitikchauhan580]

I have one question since 12th: Why insertion or deletion of multiple of 3 bp is not a frame shift mutation? Insertion may be any where, I may be b/w two codons or b/w bp of one codon.

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Is dna is most susceptible to uv radiation?

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Thanku sir

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In the quest to understand the basis of infertility in humans, researchers have identified a mutation in a gene associated with chiasmata. This protein normally acts to promote homologous recombination.
Why might a defect in homologous recombination have consequences for fertility?

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Sir please help us to learn about Pcr amplification

[@shomusbiologyofficial]

Video is already there

[@Christopher_Mang]

Can there be any mutation without foreign agent or factor?

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Does the mutation occur in every cell simultaneously or does it occur in one cell and we call it a mutation?

[@shomusbiologyofficial]

It start with one cell then it spreads to multiple cells

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Super

[@christoffer4862]

WHY do genes mutate, what are the mechanisms and factors in the frequency?

[@tuniyabeemroth1140]

Genes mutate by these factors like-:(1)temperature may cause changes.(2)alpha,beta,gamma rays and so on.....Hope ur doubt may clear

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Sir please explain Hprt assay

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Help me what is one copy of a double mutation mean, I need help understanding

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Nyc

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nice it's very helpfuf,

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Well

[@harsinmuhammadhamid5027]

Thank you, but I have a question, how mutation (which is almost all bad)is the basis of (evolution)?

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It can be good too

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sir I m not able to.understand...what is CLB method and what is attached X..method??..plzzz sir help me to understand this via ur lecture as soon as possible .. bcz my exams are coming 😞

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🙂🙂😚😚 exam is coll

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sir hindi Mena lecture

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In case of humans how to mutate a gene for own benifit , like if some genes are responsible for memory power we can mutate the gene and creat a intelligent person like einstein

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Hi