DNA Ligase enzyme and it's mechanism | DNA ligation | Bio science

DNA Ligase enzyme and it's mechanism | DNA ligation | Bio science
DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms may specifically repair double-strand breaks.
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[@sravyasunkara1995]

Clearly explained about the ligase enzyme thanku

[@mulasubramanyam422]

Tq sir for your nice video

[@tirthagaonkar7885]

very nicely explained. THANK YOU

[@architverma483]

bro you explained very well BUT,
All the three phosphate group are utilized in the formation of phosphodiester bonds 1 phosphate group is form the bond and the remaining two phosphate groups are consumed as a form of energy.

[@mulasubramanyam422]

Gud experience

[@sadafzaheer120]

Thank u so muchhhh very helpful

[@bioscience6853]

My pleasure

[@lemmymukoso5022]

Nice explanation

[@parvatimeena1687]

Very nice Bro.. Keep it up

[@bioscience6853]

☺☺

[@aravindgajjela9415]

Thank you

[@bmkrishnam4756]

Super explanation

[@karmacheme8421]

Thankyou Sir very well explained

[@bioscience6853]

My pleasure

[@tamadakameshwararao4263]

Such a nice explaination

[@bioscience6853]

☺☺

[@sumikhadeeja1267]

Nice explanation thank u

[@bioscience6853]

My pleasure

[@BiologyRoots]

Is this process same for T4 dna ligase?

[@sai_editz_0137]

NH Lys ani rasaru what is it mean could you explain it again

[@rthmjohn]

So, just to be clear, the two phosphates from the ATP will be eliminated?

[@bioscience6853]

Exactly

[@mulasubramanyam422]

Sir could you plz keep neural control and coordination

[@mulasubramanyam422]

Thanks sir

[@mulasubramanyam422]

❣️

[@abirbanerjee7100]

How many nucleotide can be added by lygase enzyme?

[@Champion9255]

You didn't explain what ligase actually does.. You just showed the ligation.

[@bioscience6853]

That ligation will be done by that ligase enzyme which i shown u clearly

[@Champion9255]

@@bioscience6853 I must have missed it. Where did you mention the OB fold domain and the adenylation domain making up the catalytic core of LIG, as well as other specialized domains such as the dna binding domain in LIG I

[@bioscience6853]

This explanation is for bsc level. Not for msc brother

[@Champion9255]

@@bioscience6853 I am a third year bsc student