Pulmonary Artery Hypertension | Clinical Medicine

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Ninja Nerds!
Professor Zach Murphy will be presenting on Pulmonary Artery Hypertension (PAH). We will be going into detail on the following main objectives:
1. Definition and Classification of Pulmonary Artery Hypertension
- Understand what pulmonary artery hypertension (PAH) is and how it differentiates from other types of hypertension.
- Familiarize yourself with the World Health Organization (WHO) functional classification system, which categorizes PAH based on symptom severity and limitations in daily activities.
2. Pathophysiology and Etiologies
- Delve into the underlying mechanisms that contribute to PAH, including vasoconstriction, vascular remodeling, and inflammation.
- Examine the role of various risk factors such as genetics, connective tissue diseases, and drug exposures in the onset and progression of PAH.
3. Clinical Manifestations and Presentation
- Learn to identify the common signs and symptoms associated with PAH, including but not limited to dyspnea, fatigue, and chest pain.
- Discuss the markers of disease severity and progression, such as exercise intolerance and the occurrence of syncope.
4. Diagnostic Criteria and Tools
- Understand the utility and interpretation of diagnostic tests like echocardiography, right heart catheterization, and pulmonary function tests.
- Familiarize yourself with the latest guidelines and consensus criteria for diagnosing PAH.
5. Initial Management Strategies
- Discuss evidence-based approaches for initial patient stabilization, focusing on pharmacotherapy with agents like endothelin receptor antagonists and phosphodiesterase-5 inhibitors.
- Understand the indications for supportive measures like oxygen therapy and diuretics.
6. Definitive Management Approaches
- Explore advanced treatment options such as prostacyclin analogs, soluble guanylate cyclase stimulators, and surgical interventions like lung transplantation.
- Evaluate the risks and benefits of each management strategy in light of the most current research and guidelines.
7. Complications and Prognosis
- Understand the potential complications of PAH, including right ventricular failure and arrhythmias.
- Discuss prognostic factors that can influence long-term outcomes, including WHO functional class, exercise capacity, and hemodynamic parameters.
Table of Contents:
0:00 Lab
0:07 Pulmonary Artery Hypertension (PAH) Introduction
0:37 Pathophysiology | Type I PAH
3:37 Pathophysiology | Type II PAH
5:39 Pathophysiology | Type III PAH
7:29 Pathophysiology | Type IV PAH
8:55 Complications | Right Heart Failure
13:17 Diagnostic Approach
17:26 Treatment
17:53 Vasodilator Therapy
19:52 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Pulmonary Hypertension...
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[@josephnorton9861]

Awesome video.. My son just became a PA in the cardiology dept. So he sends me cases and I learn and send him material also. Fun TY

[@mikefoster3582]

We love Ninja Nerd videos at our school here in Eldoret, Kenya. Small correction: at first of video you stated 5 classes of PH, but you wrote PAH. PAH is a subclass of PH. FYI

[@lemonfilloren2668]

Wow! That was very well explained. Very easy tp understand!

[@auroramojica5402]

Thanks for your videos!!! I am a cardiovascular sonography student and find ninja nerd videos to be helpful. I like the drawing out things on the board and the way things are explained.

[@hazaralaabed551]

WOW WOW WOW 😮
Thanks a lot
Couldn’t miss it due to the amazing experience of your previous lectures specially the newly updated ones

[@meryemmeryem5841]

It was very helpful. Thank you so much!

[@user-tj2hz7xu1e]

thank u so much, this was a great explanation.
you are the best!

[@user-ke9jl9uy1q]

As always, thank you😊

[@Natalia-RN]

Thank you❤

[@jackswinger8781]

Thank you so much 🤍

[@tmu8396]

really appreciate

[@luphelelemavuso8594]

Thank thank thank❤

[@user-ec1uy8jl3i]

Amazing ❤❤

[@Medperfect]

thank u

[@tanupriya5962]

Please make video on rare disease case we want to know the mechanism of disease which not available on youtube❤❤

[@osamaaljassem4256]

Very Very Nice

[@ananyaarya1736]

Thankyouuu

[@alimazin1]

You are amazing
Thank you

[@NinjaNerdOfficial]

Welcome 😊

[@mutharasans7207]

Please make a video of Pulmonary edema....

[@donnabetty9993]

Now I understand much better. I've been tolld that I have high pulmonary pressure and at high risk for stroke.

[@gracewulansari8907]

hi there is there any device can be implanted between left atrial and right atrial to regulate the flow ? it might help the symptom

[@ScottSchellhammer]

"Repetio es mater de estudio" is your forte Zach

[@WafaaJawesh]

❤❤❤

[@drfabsoonjd]

I have this condition. I am so sad that I can’t do what I used to.

[@SerenitywithLawna-Merry]

I think that having pulmonary arterial hypertension is a continuous cycle of grief... it ebbs and flows or at least that's what the last six months of my life have taught me since receiving the diagnosis. I hope that you are able to be gentle with yourself, and know that you can find ways to enjoy life in new ways so long as you are not hellbent on spending a lot of energy on hating the life you do have. I've started Serenity with Lawna which is the channel I'm posting this comment from to educate people about what its like living with this condition but also to find better ways to work with others so we can have some sort of quality to our lives. Hope you'll come check my videos, but mostly just hope you'll find peace. Sending light and love.

[@BeautyByCall]

I also have this condition,yes that's true your life changes, thanks SerenitywithLawna for your advise thanks a lot

[@cassandrakrupa7722]

I hate having this 😢

[@nannon591]

I didn't get why hypoxemia cause pulmonary hypertension???

[@WafaaJawesh]

V/Q mismatch