In the graph at 4:50, did you perhaps accidentally swap mobile with immobile proteins? It would seem to me that if the ROI recovers its fluorescence close to 100% before photobleaching, it would be due to diffusion of proteins
Could you go into more detail on what's happening in the sides of the fish keratin cell? If not much is known, maybe just an addendum to help define the 'tightly packed network'. Love your explanations :)
The sides of the cell are a lot like the back: actin is disassembled there to promote "pulling in" the sides so the cell moves forward and isn't torn in half! Actin filaments grow at one end and break down at the other end, and they can form branching structures with the help of accessory proteins (notably Arp2/3). Many, many proteins are involved in controlling how fast and where actin forms filaments! This video is just the tip of the iceberg on how actin contributes to cell crawling :)
This was the best explanation for anything I've ever asked ever.
Thanks! 🥰
Great explanation! Thank you for this video. Science can get overwhelming sometimes...until people like you simplify it, then, it is fun again!
Glad I could help make science fun again!
The best explanation on TH-cam! Thank you so much!
Love the music and love the bird's eye view explanation!!!
oh my gosh this was so helpful for my cell and molecular bio class amazing job and THANK YOU SO MUCH!
So clear ad interesting tutorial. Always fascinated with scientists' great invention
Such a good way of teaching. 10/10.
I absolutely understand it now.
Wish I met your channel earlier 😁
What a legendary explanation, Diamond. Thanks
This is such a good video. It is clear that you guys know how to explain difficult htings in a way everybody can understand. Thanks!
Thank you so much! Awesome explanation!
This is such a good content!
Excellent video. Thank you!
great video! super cool
In the graph at 4:50, did you perhaps accidentally swap mobile with immobile proteins? It would seem to me that if the ROI recovers its fluorescence close to 100% before photobleaching, it would be due to diffusion of proteins
This is great
Mam can you do a video on Fret technique
Gaylord Wall
Could you go into more detail on what's happening in the sides of the fish keratin cell? If not much is known, maybe just an addendum to help define the 'tightly packed network'.
Love your explanations :)
The sides of the cell are a lot like the back: actin is disassembled there to promote "pulling in" the sides so the cell moves forward and isn't torn in half! Actin filaments grow at one end and break down at the other end, and they can form branching structures with the help of accessory proteins (notably Arp2/3). Many, many proteins are involved in controlling how fast and where actin forms filaments! This video is just the tip of the iceberg on how actin contributes to cell crawling :)