Endochondral Ossification

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  • เผยแพร่เมื่อ 29 ก.ย. 2024
  • Endochondral ossification is the primary method for bone formation in the body. This video covers the process in a step-by-step method to help you understand exactly what is happening.
    Video Number- Anatomy 1 -11

ความคิดเห็น • 129

  • @roberte.6892
    @roberte.6892 4 ปีที่แล้ว +167

    Why do professors and authors refuse to teach like this? In a way I can understand. Thank you, thank you, thank you!

  • @Abdul-Y
    @Abdul-Y 4 ปีที่แล้ว +1

    So the primary ossification center of endochondral ossification was an intramembranous ossification center in the beginning, then turned to endochondral production after the gap formed by nutrients deficiency?

  • @ReasonsToSmile789
    @ReasonsToSmile789 9 ปีที่แล้ว +1

    I also tried to access your website, however, it seems to be 'unavailable', will it be up and running soon?

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +1

      Sou Keng Leng Hi Sou, yes the website will be back up and running very soon, however at the moment TH-cam has the majority of my lessons :). I will get back to the videos as soon as possible, just had to take a little bit of time off for a surgery. If you ever need any specific help, feel free to email me directly at asher.kidd@gmail.com Good luck with you studies!

  • @dreamerking5511
    @dreamerking5511 8 ปีที่แล้ว +253

    i am better than i was 13min ago. thankyou

    • @MrPridizzle
      @MrPridizzle 7 ปีที่แล้ว +6

      I am better than I was 6.5 minutes ago [watched on 2x speed]. thank you.

  • @rebeccayhb
    @rebeccayhb 9 ปีที่แล้ว +58

    first of all, your drawings are cute! i've looked through enough of explaining of how ossification process forms bones, yet most of them just confuse me with tons of words that i still struggle to remember. love how you explain everything so clearly. keep it up!!

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +5

      七七宝 You're very welcome, thanks for your feedback :)

  • @yuridesu7969
    @yuridesu7969 6 ปีที่แล้ว +19

    OMG NOW I GET WHAT THAT OSTEOBLASTS DOES AND WHERE IT IS COMING FROM! THANK YOU SO MUCH I CANT THANK YOU ENOUGH.

  • @DavidLee-jp6sd
    @DavidLee-jp6sd 7 ปีที่แล้ว +26

    You're the reason that I'm gonna pass my exam tomorrow. You rock! Thank you for dispensing that knowledge in a way that even I can understand.

    • @daisyruiz6194
      @daisyruiz6194 3 ปีที่แล้ว

      did you pass?

    • @DavidLee-jp6sd
      @DavidLee-jp6sd 3 ปีที่แล้ว +1

      @@daisyruiz6194 can't remember this exam but i finished the semester with a 4.0! videos like these no doubt saved my life.

    • @daisyruiz6194
      @daisyruiz6194 3 ปีที่แล้ว

      @@DavidLee-jp6sd wow thats so great. I’m struggling so bad tanking my gpa at 2.5

  • @aryaa3998
    @aryaa3998 8 ปีที่แล้ว +7

    I love your handwriting and your accent!

  • @Seenshadow
    @Seenshadow 3 ปีที่แล้ว +1

    Why would the osteoblasts create spongy bone just so it can be degenerated by osteoclasts in the next step later?

  • @colettebatman5888
    @colettebatman5888 7 ปีที่แล้ว +7

    As I have commented before your videos are the best...easy to watch over a few times without the slapstick humor in other videos...your handwriting is perfect 👌

  • @ghadaghada8150
    @ghadaghada8150 3 ปีที่แล้ว +5

    online med school has been hard, this just made my life easier! thank you

  • @15aacc
    @15aacc 7 ปีที่แล้ว +9

    Great video! Any chance you can turn on closed captioning ?

  • @archiejames3912
    @archiejames3912 6 ปีที่แล้ว +5

    Firstly, thank you! This video is really helpful.
    I just wanted to know at which point the periosteum appears, and how it does so? Something to do with Perichondrium?

  • @adnanasif7354
    @adnanasif7354 2 ปีที่แล้ว +3

    Now I can completely understand all the process of endochondral ossification.. Thank you soo much

  • @ReasonsToSmile789
    @ReasonsToSmile789 9 ปีที่แล้ว +31

    Hi Asher!
    I'm currently taking a anatomy& physiology course over the summer and I find your videos to be very helpful. Please continue making these videos and educating students about the human body!:D

    • @amrali1801
      @amrali1801 3 ปีที่แล้ว

      I am still 1st year
      Feelz upset 😡
      Still 5 years up to go for me

    • @ZainRules25
      @ZainRules25 ปีที่แล้ว

      @@amrali1801 same

  • @Emma-hx7yw
    @Emma-hx7yw 6 ปีที่แล้ว +3

    Your videos are so helpful ! thank you so much (from a French medical student ;) )

  • @saisumanth2378
    @saisumanth2378 5 ปีที่แล้ว +2

    Thank you very much that was very good🙏

  • @Daniel-tv1fe
    @Daniel-tv1fe 4 ปีที่แล้ว +3

    Really useful during quarantine. Thank you.

  • @Ali-wp9qy
    @Ali-wp9qy 7 ปีที่แล้ว +2

    To me it seems as though step 1 is moreso describing subperiosteal ossification as opposed to the internal endochondral ossification, anyone else agree? I'm having a hard time differentiating the two and this seemed to make that complication a bit worse for me - nonetheless, a very helpful video!

  • @milamauran4169
    @milamauran4169 3 ปีที่แล้ว +1

    Hello, great video! You help me a lot
    Could you add subtitles please

  • @andreiratiu7240
    @andreiratiu7240 ปีที่แล้ว +2

    You did an amazing job explaining this. You've helped more than you can imagine with studying from my textbook. Keep up the work you do 🙏

  • @nyile012
    @nyile012 7 ปีที่แล้ว +2

    Thank you !Thank you !Thank you !
    Thank you !Thank you !Thank you !
    Thank you !Thank you !Thank you !
    Thank you !Thank you !Thank you !
    Thank you !Thank you !Thank you !
    :)

  • @Akira_1008
    @Akira_1008 4 ปีที่แล้ว +1

    Question: you wrote in the second picture that osteoclasts degrade cartilage matrix. I though osteoclasts only degrade bone matrix?

  • @AjayKumar-wb9uh
    @AjayKumar-wb9uh 4 ปีที่แล้ว +1

    Please upload more videos...

  • @fcrick6967
    @fcrick6967 3 ปีที่แล้ว +1

    thank you very much indeed!

  • @vijayramaraju3522
    @vijayramaraju3522 2 ปีที่แล้ว

    Hello sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off crack line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....

  • @raymondclark5628
    @raymondclark5628 6 ปีที่แล้ว +1

    Nicely done. However, a minor correction - your sesamoid bones (such as your paired patellae) do not form via endochondral ossification. They form by intramembranous ossification.

  • @kenedynatumanya5543
    @kenedynatumanya5543 3 ปีที่แล้ว +1

    Waooo,,, like it

  • @volimantra
    @volimantra 5 ปีที่แล้ว +1

    Is this an Australian or a British accent

  • @philpegg
    @philpegg 5 ปีที่แล้ว +1

    which device/ software did you use to draw and record this? I am looking for an efficient digital way to store notes

  • @ameenalbostany266
    @ameenalbostany266 8 ปีที่แล้ว

    Damn thanx for ur fucking good video

  • @anonymousanonymous9831
    @anonymousanonymous9831 9 ปีที่แล้ว +1

    I thought cartilage was a vascular.
    In order for blood vessels to be present there needs to be channels?

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว

      Mature cartilage is avascular, correct :). But as with any building process in the body, temporary vascularisation helps with delivery of essential components. Once the whole process is complete, the only component of the bone that has direct nerve and vascular tissue is the bone itself.

  • @gvstaden
    @gvstaden 8 ปีที่แล้ว +2

    Awesome explanation!! Love your vids, thanks for posting.

  • @Shigellosis
    @Shigellosis 6 ปีที่แล้ว +2

    fantastic video! I learned & got engaged more in 13 minutes than I have been for the last 2-3 weeks. Thank you!

  • @gibcote
    @gibcote 9 ปีที่แล้ว +1

    Once the chondrocytes start dying, you've mentioned that a central "clearing" begins to appear as the calcified matrix begins to deteriorate. Does all of the matrix get disintegrated? Or parts of the calcified matrix are retained and provide a scaffolding to the osteoblasts to secrete osteoid? Please help.

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +1

      Hi Neely, you can think of the osteoblasts following the cartilage border as it deteriorates. This central clearing is what will become the medullary cavity, this is where we house yellow bone marrow, no osteoid type cells are there at all in the much later stages. I hope this answers your question, all the best!

  • @HumaWazir-v3e
    @HumaWazir-v3e 4 หลายเดือนก่อน

    It's an Amazing Video !! Thanks A Zillion Sir!✨

  • @rigzinangmo6948
    @rigzinangmo6948 5 ปีที่แล้ว +1

    Thank you so much . Helped me a lottttttttttttttttt.....u are too good

  • @sabashah3119
    @sabashah3119 4 ปีที่แล้ว +1

    I feel like he said last step like 20 times.

  • @omarmejiamorales9802
    @omarmejiamorales9802 4 ปีที่แล้ว +1

    your videos are incredibly useful. Thanks very much for sharing them.

  • @grounding123
    @grounding123 9 ปีที่แล้ว +2

    Great tutorial, I appreciate the clear and precise way it was taught-- you are a natural. Thank you!

  • @maviosmachethe144
    @maviosmachethe144 7 ปีที่แล้ว +1

    your videos play important rule in my course ,thanks

  • @danila.5181
    @danila.5181 ปีที่แล้ว

    7:18 why do osteoclasts resorb the cartilage and not chondroclasts? I dont understand 🙁

  • @realsnipercat
    @realsnipercat 8 ปีที่แล้ว +16

    Hi. You mentoned that endochondral ossification occurs for all bones below the skull with the exception of the clavicle. But what about the ribs, scapula and bones of the pelvis?

    • @mehakhussain8948
      @mehakhussain8948 8 ปีที่แล้ว

      those are just flat bones. I don't think they undergo this process.

    • @lfc_1233
      @lfc_1233 6 ปีที่แล้ว

      Tonmoy Khan they undergo intramembraneous ossification

    • @rznotorious6103
      @rznotorious6103 5 ปีที่แล้ว

      Ribs and bones of pelvis by endochondral ossification, not sure abt scapula

    • @RhodaChisanga-hw6qb
      @RhodaChisanga-hw6qb 6 หลายเดือนก่อน

      They undgo In intramembranous ossification

  • @HafizahHoshni
    @HafizahHoshni 6 ปีที่แล้ว +1

    Thank you for this great video! Very helpful and you explained it very well. Thank you 1/8/2018 :D

  • @sulekhanair2351
    @sulekhanair2351 4 ปีที่แล้ว

    what is central clearing ?

  • @saraedwards9499
    @saraedwards9499 6 ปีที่แล้ว +1

    Thank you! I feel much better about answering test questions about this tomorrow!

  • @romandean6541
    @romandean6541 5 ปีที่แล้ว +1

    Pleasd tell me sir.... At what age this growth stops

  • @phreshbrocoli
    @phreshbrocoli 8 ปีที่แล้ว +1

    do scapula and sternum also undergo endochondral ossification? I thought they were flat bones.

    • @nameless9491
      @nameless9491 8 ปีที่แล้ว

      The scapula undergoes intramembranous ossification and the sternum undergoes endochondral.

    • @mohammedbinsaleem5365
      @mohammedbinsaleem5365 7 ปีที่แล้ว +1

      I think sternum also undergoes intramembranous ossification

  • @DrHouse-iy8sn
    @DrHouse-iy8sn 8 ปีที่แล้ว +1

    Very good video. Thanks!

  • @chrisanderson7304
    @chrisanderson7304 7 ปีที่แล้ว +1

    Hi. Do you have the reference list?

  • @leapofthefrog
    @leapofthefrog 9 ปีที่แล้ว +2

    How do the enlarging chondrocytes signal the surrounding cartilage to calcify? I thought you had to have osteogenic cells for that to happen.

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +1

      +leapofthefrog Hi there, I believe you may have calcification confused with ossification?, which part of the video are you referring to. I'll have a quick look and try help out.

    • @leapofthefrog
      @leapofthefrog 9 ปีที่แล้ว

      +Medic Tutorials It's at about 3:57.

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +1

      +leapofthefrog Ah yes I see where you're at :). It's definitely the chondrocytes that secrete in this phase. They are not sending a groth message as such, just releasing intracellular components that cause matrix hardening and subsequent chondrocyte death due to lack of nutrients. You can think of it as an extremely tightly regulated form of controlled cell death.

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว +1

      +Medic Tutorials growth* derp :p

    • @leapofthefrog
      @leapofthefrog 9 ปีที่แล้ว

      Ah, thanks.

  • @phoco4
    @phoco4 6 ปีที่แล้ว +1

    your saving my collective ass! literally

  • @kanyisolaodusanya8369
    @kanyisolaodusanya8369 9 ปีที่แล้ว +1

    i wish the diagram was bigger, damn.

  • @shiyaraibrahim9653
    @shiyaraibrahim9653 7 ปีที่แล้ว +1

    I was wondering whether the scapula is an intramemberanous ossification or endochondral ?

    • @davidfazylov2090
      @davidfazylov2090 7 ปีที่แล้ว

      Most bones of the body develop through endochondral ossification including the scapula, vertebrae , ribs, sternum, pelvic girdle, and bones of limbs.

    • @syamimijalalal4660
      @syamimijalalal4660 7 ปีที่แล้ว +1

      scapula undergo intramembranous ossification, because scapula is a flat bones. other example of flat bones is ribs.you should see another of the his vid tittle intramembranous ossification

  • @pr00t33
    @pr00t33 2 ปีที่แล้ว

    the intro song is absolute garbage, I thought it was bad because I sped it up but damn even on normal speed its bad, I love the video though!!

    • @Medictutorials
      @Medictutorials  2 ปีที่แล้ว

      Unfortunately, ya can't win 'em all. I am really glad to hear that the video was useful for you though!

  • @MrDonIlyas
    @MrDonIlyas 9 ปีที่แล้ว +1

    is it the chondrocytes that die after the calcification of the matrix at 4.45

    • @j2184
      @j2184 9 ปีที่แล้ว

      +MrDonIlyas yes

  • @taru-randomandfacts7483
    @taru-randomandfacts7483 3 ปีที่แล้ว

    WAH BETAV.WAH TUM TOU BARAY HEAVY DRIVER HOON ......

  • @anisa_nisar
    @anisa_nisar 3 ปีที่แล้ว

    3 Stages of endochondral ossification?

  • @hassamalijouhar3302
    @hassamalijouhar3302 4 ปีที่แล้ว

    thanks alot

  • @eiklinoh9402
    @eiklinoh9402 8 ปีที่แล้ว +2

    thank you ❤❤❤❤

  • @muskandilbar2615
    @muskandilbar2615 3 ปีที่แล้ว

    Why don't you upload more videos?

  • @PrettyKombe
    @PrettyKombe 5 ปีที่แล้ว

    Does it increase bone length or width?

  • @anisa_nisar
    @anisa_nisar 3 ปีที่แล้ว

    N what is formed during each stage ?

  • @nghiango6339
    @nghiango6339 3 ปีที่แล้ว

    do anyone have transcript for this video ?

  • @vyoma1998
    @vyoma1998 4 ปีที่แล้ว +1

    This was Sooo helpful! Thank you so much!

  • @gilbertgrejp
    @gilbertgrejp 3 ปีที่แล้ว

    What about the sternum and the scapula?

  • @cynthiamartinez6583
    @cynthiamartinez6583 ปีที่แล้ว

    U write fast r u using Apple Pencil

  • @onlignebridge4224
    @onlignebridge4224 3 ปีที่แล้ว

    Thanks very much.
    A question: Ossification takes place before flesh development?

  • @elif7953
    @elif7953 6 ปีที่แล้ว +1

    i came from blg guys

  • @Hydraxit
    @Hydraxit 4 ปีที่แล้ว

    Good video, but basically just a reiteration of Marieb. Nevertheless, thanks for uploading!

  • @sheilagonzalez5398
    @sheilagonzalez5398 ปีที่แล้ว

    thank you sooo much for your effort in making this video, it was incredibly helpful.

  • @skhprwdm
    @skhprwdm ปีที่แล้ว

    Ossification enchondrale ❤

  • @DrP3natrator
    @DrP3natrator 9 ปีที่แล้ว +1

    Thank you. Good video!

  • @muayadgh6325
    @muayadgh6325 ปีที่แล้ว

    Wow ! Thank you so much. Was struggling for a whole hour.👏👏👏👏

  • @BabeeMilly
    @BabeeMilly 2 ปีที่แล้ว

    Where do the chondrocytes come from?

  • @maryammotamedian
    @maryammotamedian 3 ปีที่แล้ว

    thank you so much. I am going to watch all your videos. please make more

  • @paparon90fon
    @paparon90fon 6 ปีที่แล้ว +1

    Thanks again bro

  • @nessar6531
    @nessar6531 6 ปีที่แล้ว +1

    Thank you!

  • @lanana939
    @lanana939 5 ปีที่แล้ว +1

    This is great thank you :)

  • @ratikamahato8401
    @ratikamahato8401 5 ปีที่แล้ว

    How the periosteal bud formed???

  • @lucyb5028
    @lucyb5028 ปีที่แล้ว

    That was massively helpful and I really appreciate the visual aspect with clear explanations and colours, thankyou 😆

  • @mariammariam117
    @mariammariam117 3 ปีที่แล้ว

    Iam stupid i dont get it

  • @sudheeshna2424
    @sudheeshna2424 3 ปีที่แล้ว

    Please make a video on mechanism of cytotoxic t-cells

  • @czyu788
    @czyu788 7 หลายเดือนก่อน

    Thank you Sir

  • @inspired.art_o7331
    @inspired.art_o7331 11 หลายเดือนก่อน

    Thank you sir ....

  • @tarunssangha7605
    @tarunssangha7605 2 ปีที่แล้ว

    Thank you this was a very useful video👍

  • @saronsin7308
    @saronsin7308 9 ปีที่แล้ว +1

    super helpful, thanks!

    • @Medictutorials
      @Medictutorials  9 ปีที่แล้ว

      You're welcome Saron, glad it helped

  • @DanseurPetite
    @DanseurPetite 2 ปีที่แล้ว

    Thank you so much! This actually makes sense!

  • @julissa6715
    @julissa6715 3 ปีที่แล้ว

    Thank you so much for this video, you are a life saver!

  • @animon87
    @animon87 6 ปีที่แล้ว +1

    Perfect for me 👌

  • @lionsinescanor373
    @lionsinescanor373 ปีที่แล้ว

    great video!

  • @cameronwarttig1732
    @cameronwarttig1732 ปีที่แล้ว

    Handy

  • @alexandriafournier2497
    @alexandriafournier2497 2 ปีที่แล้ว

    this video helped so much

  • @gabrielagattelli5999
    @gabrielagattelli5999 5 ปีที่แล้ว

    Thanks for the explanation

  • @ronakonina
    @ronakonina 7 ปีที่แล้ว

    thanks for a helpful video!

  • @priscilla2525
    @priscilla2525 5 ปีที่แล้ว

    SO helpful. Thank you!

  • @ollymac2580
    @ollymac2580 8 ปีที่แล้ว

    Thank you so much this is top stuff.

  • @SuperYaniv12
    @SuperYaniv12 3 ปีที่แล้ว

    Thank you!!!

  • @sweet_panda9248
    @sweet_panda9248 5 ปีที่แล้ว +2

    this made me more confused.

  • @max_hanma
    @max_hanma 2 ปีที่แล้ว

    Who else is here because of a personal trainer course , like I did not expect to be digging this deep lol