Dave Feldman - 'Interpreting Common Low Carb Lipid Profiles'
ฝัง
- เผยแพร่เมื่อ 30 มิ.ย. 2024
- Dave Feldman is a senior software engineer, business developer and entrepreneur. He began a Low Carb, High Fat diet in April 2015 and after experiencing a significant rise in his total cholesterol he committed himself to learning everything he could about cholesterol and the lipid system.
As an engineer, Dave spotted a pattern in the lipid system that’s very similar to distributed objects in networks. Through research and N=1 experimentation he has revealed some very powerful data which he continues to share in this presentation and in further detail on his website; www.CholesterolCode.com - วิทยาศาสตร์และเทคโนโลยี
The thing I love most about keto is that ll of the presentations are backed up by actual information. There’s actual data.
The typical doctor, who subscribes to the conventional wisdom, when confronted by the breadth and cogency of the work that Dave Feldman has done, should be embarrassed. Despite not being a medical professional, Dave Feldman, as a software engineer, brings more clarity to the issue of lipidology than most doctors bring to the public concerning that topic. Thank you Mr. Feldman for all the great work you do. You are proof positive that some of the most substantive changes take place when outsiders to a particular issue get involved in the conversation. I would rather listen to you, and another engineer, Ivor Cummins, more than most of the doctors that surround me - men and women who still seem intent on adhering to the same old dogma that they were indoctrinated with decades ago.
says a lot about the medical professionals... most are looked in on what the current state of science seems to say is facts and they hardly can act against it nor ever question it publicly as its most likely causing them more trouble...
completely agree :) But as a medical professional there are SOME of us who know the place of a LCHF minimally processed paleolithic diet. Fat doesn't make one fat; insulin resistance from carbs does :) Convert one doctor at a time :)
What the public does not know is that most of the people we call doctors are merely physicians. This is similar to the difference between an auto technician and and automobile engineer. Or a computer technician and a computer engineer. It is not really the fault of the physicians; they are not taught to think critically, to analyze data or the design and function of the complex and interacting functions of the human body., or question assumptions. Physicians are taught to memorize labels - of anatomical structures, drug names, and also to (hopefully) use a diagnostic tree.
Physicians are essentially taught not to think - but what information to regurgitate. During their training and in practice, physicians can be penalized for thinking. few physicians these days work as independent professionals. If they work for an organization, they typically must adhere to 'Standard of Practice', and provide standard care.
@@Jefferdaughter More accurate to say that they're taught to minimize the risk of liability or a finding of professional misconduct. High cholesterol => prescribe statins. No ifs, and or buts. No judge or jury would rule against them for doing that. No doctor would testify against them. Ch-ching, cash the cheques and go home. Easy peasy.
@@gabrielyee9458 Chronic partial IR from any cause causes fatness. Just so happens that carbs cause it in almost everyone
Great piece, Dave. Had a heated argument with my GP who was very strident that I should go on a statin. I repeatedly mentioned my HDL/Trig ratio and he told me to "put Triglycerides aside for one moment because the 'bad' cholesterol...." at which point point I lost my rag and told him that his advice was always welcomed but the decision is, ultimately, mine. Sometimes it's just such a struggle to resist being pidgeon-holed.
Keep up the great work.
I applaud your non conformism.
Yeah, I'm a high HDL/lo TG/astronomical LDL guy on a LCHF diet. My cardiologist said, "ratios don't matter, TG doesn't matter. Only total cholesterol matters." Of course he strongly advised statins. When I demurred, he suggested the calcium CT scan. I asked how much radiation is that? He said "oh, about the equivalent of 100 xrays. F that! He doesn't put stock in CIMT, because it only deals with the carotid artery, which is far from the heart. I want to have faith in Dave's approach, but I've also got two kids who need me around for another 8-10 years.
Questions, not statements.
"Show me the mechanistic reason my LDL being high is bad."
Medical doctors prescribe medicine. It’s all they’ve got.
@@samuelreiter6412 Yep. Drugs and surgery.
Thank you for all your amazing work Dave. It is indeed a gift for humankind. I hope you win a nobel prize someday.
Out of all the Low Carb people I think Dave Feldman has the most open mind. Most of the other MD's I see just selling information (or books) or just adding to the echo chamber with anecdotes.
My fave low carb speaker and researcher/engineer. So awesome!
Thanks for making this public.
Excellent talk. Thank you, Dave!
It is funny. Not too long ago, I will question a non-professional delving into matters unrelated to his field of expertise. After watching Dave and Ivor, I realized there are things an outsider can see which the professionals cannot relate to because they are held by their pre-conceived education and training.
Hey, guess what? Low carb eating is NOT a field where conventional doctors are experts. In fact, they are the most ignorant when it comes to keto and carnivore. They still insist that the SAD diet is the best for you, even though the obesity rate and type 2 diabetes rate in this country has sky rocketed in the past 30 years. I would rather place my trust in an outsider's viewpoint than "conventional wisdom". "Conventional wisdom" was invented and pushed by big food and big pharma companies.
Both of you, well said. I can tell you shocking stories underlying what you say
plus Engineers more intelligent than docs anyways...?
I'm a pharmacist... Can confirm, medical/nursing/pharmacy school is just big pharma indoctrination. It consists of "here's a problem, here's the drug to treat it"... Anything outside of that paradigm is either blown off as wrong or simple, outdated info.
It takes an open mind and self-education to undo the 4 years of medical/pharmacy school.
Appeal to authority is the worst fallacy we commit. We see someone with the expert uniform(lab coat) and now socially we treat them like a psuedo priest class. People assume these experts have their best interest in mind and are open minded. Science is a method of exploration and experimentation not a truth telling tool.
Wow this presentation and the info in it is great!!
This has been tremendously helpful, as I was on a low-carb diet for about 6 months and a recent lipid panel came back with scarily high LDL and total cholesterol. My doc went into overdrive lecture mode regarding risk factors, etc. While I am adding more fiber and cutting out most dairy and red meat, I feel that I don't have to freak out and think that I totally screwed up my system with bad fats and keto. I love the reminder that guidelines are not always correct/accurate or suitable for everyone.
Why cut out red meat?
1. You don't need fiber, 2. fermented full fat dairy (cheese,plain yoghurt) is OK, 3. Don't cut out red meat - fatty read meat is 'heart healthy'.
Me too and Dr is freaking out. Not willing to go on statins. Fight will commence next month
Excellent information 🙂👍!!!
Glad he mentioned the possible glucose sparing in Lean Mass Hyper Responders. I fit the profile and my GP freaked out, afraid I’ll keel over any minute.
I have glucose sparing after 1.5 years of keto. My variability is very low in glucose And in fact after eating my glucose drops! 🤷♀️
Great vid. Thx for posting!
Thanks for the education!!!
One of the best talks to help me put my own bloodwork in context. High fasting glucose but very low fasting insulin, high HDL but very low trigs and moderate to high LDL. Distance runner and weightlifter.
Dave, I think you hit on something very important at 28:28. "Too much of an energy surplus" is probably a big issue for most people trying to get Triglycerides lower, or keep them low. Excessive energy intake can only increase Triglycerides. Even excessive low GI foods can cause a high GL. Most people I know do not bother to track calories, or don't do it accurately, so by the time they find out they are gaining weight, they have been over consuming consistently for a long time, and they wonder why their healthier diet is not working for their weight or their cholesterol numbers. They also don't have any idea what their maintenance calories are, so calories are likely excessive on average, by default. I've found the on-line BMR calculators to be mostly useless because they are far too generic. Maybe they get you within +/-300 calories per day, but that is not close enough. Plus, the maintenance number is a moving target.
Simple calorie calculation is pounds x 10 = BMR =Basic metabolic requirement [ lying in bed motionless ] BMR x1.3 =for light work, office etc,.BMR x1.4 =moderate exercise. BMR X1.5 =for heavy exercise . etc. Simple enough to remember
Great talk, Man
So, I guess I'm a hyper responder? After going on the diet and losing 45lbs my cholesterol (ldl mostly) spiked a lot. HDL low and triglycerides low. I'm confused. My dr wanted to put me on meds and I said no way. I'm improving in every other aspect so there's no way I'm stopping now. I feel TONS better. Headache migraine improving (rare now), arthritis (cut my meds by 2/3), fibromyalgia pretty much gone, GERD improved 80%, anxiety lessened 80%, panic attacks pretty much stopped. Stopped many of the medications I was on before.
Don't worry LDL. Google UCLA study. Shows out of 136k heart attacks half had LDL in the ideal range.
Brilliant!
How does your info and research relate to familial hypercholesterolemia?
Thanks
Love this guy .the way he is presnting
Please talk more about inherited lipoprotein (a). It has great relevance to all that you are sharing.
Hi! The observation about sudden lowering of hdl being an indicator to cancer could also correlate to acute health affections? I had a drop from 71 to 52 and I was literally sick from toxoplasmosis when I took the last blood test. It seemed prety intense to me. Could it have happened due to being sick? There was christmas in between... 🤦♀️
DONT TAKE A BREAK FOR THE HOLIDAYS!!
I lost 70 pounds, doing great, took said "break", and got back into old habits!
30 pounds and 9 months later, back on the downtrend.
9 montha is not a break
Open source science, I like it!
Dave, you should collaborate with Dr. Paul Mason.
if the goal is to remove carbs as much as possible isn't it best to go full carnivore?
Please update the website reporting tool. Thank you.
What do those studies say about the accepted “normal” or desired cholesterol levels?
this is 1 how a scientist should think
2 how a scientific journalist should present
In 2012, I asked my doctors (yes, I sought a second opinion) about the contradiction between risk factors: first, my very high LDL showed them very high risk; but my .7 ratio of TG/HDL was shown by others to show low risk and to be more important. My question then was which of the two better indicated, or indicated at all my risk of cardiovascular disease? All doctors I spoke with felt it was high LDL and that I'd better go on a statin right away. As far as very low TG and very high HDL I was told that, "the science isn't there yet"--even when I pursued with questions about types of LDL. May I ask a QUESTION? Does anyone know of a mitochondrial disease or metabolic disease specialist, ideally near New Haven, that might take on an older adult as a patient?
I'd be really interested in how exercise in the 12-14 hours preceding the blood draw affects the lipid panel.
FYI, by exercise, I mean all different kinds and times--so right before the tests, within 4 hours of the test, the night before, etc.
The non-MD finds beneficial outcomes that can come from behavior modification and data interpretation. The MDs find beneficial outcomes that can come via drug therapies.
More evidence to me that I need to avoid my MD.
Well said!
I find the more I avoid my Drs the better i do and feel. I got off all medicines a year and a half ago (I was on strong biologics and other drugs for autoimmune diseases). My Drs keep trying to put me on medications but I refuse and do so much better with all my dietary modifications. God gave me a path to health, why mess with it?
Hi. I have a question: how is the triglyceride/HDL related to blood pressure?
Can't give up Coffee, don't care.
So longer fasting should have the same effect on VLDL and LDL? Like 20 hours?
And if you thoroughly control your blood sugar then anything cholesterol probably doesn't matter in any case. . It is mostly inflammation that causes artery walls to be permeable to plaque. Keep BS under tight control, and keep your K2 levels up (protects artery elastin) and you pretty much protect yourself from most lifestyle self inflicted diseases.
What is BS and K2?
@@Avacado721 blòodsugar vitk2
That medical professionals are "pinging" you (is that the term?) is EXTREMELY hopeful to folks like me!
At 4:00 you measure LDL-C. The C means cholesterol in LDL (not fats) but then say that VLDLs containing fats NOT cholesterol and spike your LDL. Before it was chylomicrons with fat AND cholesterol. But then the LDL-C will be low not high because its measuring fat and not cholesterol. So the LDL will be high but the LDL-C will be low.
VLDL is 60% trigs, 14% cholesterol. LDL is 24% trigs, 32% cholesterol. HDL is 9%/14%.
I’ve just got HDL cholesterol, cholesterol level and non Hdl? I don’t have ldl listed. So not sure what that means. No tryglycerides mentioned.
What about eating raw meats and no vegetables or fruits at all? Sv3rige says all plant foods are toxic and are unnatural for humans. He says organic raw organ meats are the most nutritious such as sweetbreads, brains, kidneys, hearts, liver, tripe, blood, eggs, and raw milk. For my first time I tried eating a slice of raw liver and one raw egg and had a euphoric sensation for about half an hour.
Hail engineers.!!! Savior of humanity.!!
Looked up LDL on YT and found this vid. Had read that oxLDL would be better show of possible heart illness (clogging w plaque (Ca or fatty?)). You say best seems trigl. and HDL ratio. Can you have too high HDL? My nutrtion book says cholesterol can be lowered with biotin or vitamin C and want to test that. Has anyone else tried nutrients to feel better. Is Intima better that CAC imaging?
Can taking a blood test 2 hours after a workout alter results in a bad way?
For example:
total cholesterol: 270
LDL: 194
HDL: 49
TG: 128
Will using your 3 Day protocol raise my a1c?
It would not make mechanistic sense for it to send the BG high, but it wouldn't make sense for it NOT to tack up a mite.
Dave, what do you suppose happens to hyper responders if they are on a statin? Do they run in to an energy shortage?
I'll bet their basal insulin go up significantly to deal with the gluconeogenesis statins seem to cause "autophagy process" (ie muscle wasting).
I wonder this for diabetics that may be on metformin and a statin. It would seem this would be a really bad combination.
OMG, it has zero to do with energy. VLDLs purge fat from liver, that's all.
I have read before if you put an athlete on a statin they feel absolutely horrible and they cant do the running or marathons or the stuff they love doing. Because they do so much exercise they need the fuel to not only run but also to do the normal maintenance the body requires from all that activities. The statin stops the repairs and then they get joint pain or other issues. Feel horrible! So most will either quit the statin or quit the exercise. That's just what I had read.
If they are on statins then I and healthy people like me pay up for that.
Just recently our lab no longer ask patients to fast prior to blood lipid profiles ... go figure!!
Do I understand correctly if that means their LDL-C is lower when not fasting? But what about triglycerides?
@@Torcsen triglycerides are elevated until the 12th hour of fasting.
Have you seen any obese/high-body-fat lean-mass hyper responders?
They would have to be mildly hypothyroid.
I'm a bit confused. At the beginning he said the consumption of fat causes the liver to decrease LDL. In fact he said this in a number of his talks. Near the end he said in order to lower LDL, swap (yes I heard it🙂) the carb for the fat. Can someone 'unconfuse' me?
it's the thyroid. carbs raise t3
Hi Dave, I have been watching your work for whole year. I am quite impressed with that. But, how it can be explained, please. I am 72yo female on LC diet, no hypertension, no diabetes. TCl-399, HDL-120, TR-50, LDL-250. 3 heart attacks, last one 10 months ago and the results was STENT. All lipid profile are the same numbers, still on LC moderate Fat, regular exercises. Thank you for response.
Did you ever have a CAC score done? Just curious as it shows build up in the arteries.
Hope you are doing good !
Luba, I’m 74 with triple bypass. Went on LC diet, lost 40 lbs. but my numbers mirror yours. Doc yammers about statins which I have stoutly refused. I’m still wondering what’s up myself.
Your numbers did not *skyrocket*t MY numbers skyrocketed to 380
Mine too
He said that if you want more then fast more.
I just read the following RE carotid artery...
In the U.S. and all industrialized countries, more deaths result from heart attack and stroke than from any other cause. Increasingly it is proposed that many cardiac events occur following the rupture of minor, non-hemodynamically significant atherosclerotic plaque. Indeed many policy makers and some physicians have questioned the importance of traditional screening and treatment strategies for hemodynamically significant coronary artery lesions. As an alternative, it has been suggested that screening and treatment approaches should be guided by emerging data that support the predictive value of measures of inflammation, such as high sensitivity C-reactive protein, or of genetic markers. Our goal is review the biology of acute coronary events and the results of population-based studies and, in this light, consider the usefulness of the current “state-of-the-art” methods for diagnosing coronary heart disease.
Something I not unterstand, he says fat make ldl go down. So why on the carb diet they not go up but down more than when eat fat???
Indeed funny yes
What blood test kit does he use?
Dave, here was my first bloodwork in one year after I really watched and stayed off processed foods and did most meat and tried to stay under 20 carbs per day. I’m 64 and do no medication. Triglycerides 30, HDL 94 and LDL 194. Should I be alarmed with any of these numbers?
Your Trigs and HDL are incredible! I wish mine were that good! 👍 My Trigs were 108 (drank a lot of black coffee that day), and HDL 82. Do you drink coffee? Maybe I will have to switch to Decaf to get my numbers down to those levels.
Since my new doctor reported lab work showing I was pre-diabetic and closely following conventional guidelines (Cleveland Clinic, American Diabetes Assoc) made it worse, I began seeking online info and found a number of info sources on low carb diets. Have done very well following this diet (weight loss, A1C, blood pressure, inflammation issues. Had blood drawn yesterday, very hopeful that improvements will continue )
One channel I follow is Dr Rob Cywes, The Carb Addiction Doc. His episode 181 discusses lab work, and his target goals include Trig < 75 and HDL > 75. I have seen other presentations that come to essentially the same conclusions
In other words, your results are to be CELEBRATED!!! 👏👏🏆🥇
38:54 - People who lift heavy weights tend to have lower LDL-C. Could another explanation for this be the fact that lifting weights spikes testosterone, which is produced from LDL-C in the testes? So it quite literally is using some of the cholesterol up?
This explanation does not account for this effect in women.
Suggest a review of Dr. Paul Mason's video clarifying the LDL, Pattern A vs Pattern B. I believe your test and qualifier indicators should include a determination of Pattern A and Pattern B, LDL charts.
th-cam.com/video/NUY_SDhxf4k/w-d-xo.html
Interesting, I came back with high Hdl, low ldl, and fairly high triglycerides (although I wasn't fasted, ate lunch 2 hours prior).
In another talk this presenter stated the triglycerides stay elevated for up to 12 hours after eating. A full 12 hour fast is necessary.
@@MrDavidknigge this was also my experience
I think this presentation could have been better had he discussed how un-oxidixed LDL is healthy... and only becomes "bad" cholesterol when it is oxadized... this assumes he is familiar with that aspect of the subject.
have you scanned your arteries for plaque
Why are triglycerides always happy? They always make me unhappy [GRIN]
@tjsavage711 to a point. after the point it triggers repulsion.
How can black coffee increase Trigs?? Regular black coffee with no cream or any sugar makes no sense increasing Trigs. There has to be another factor.
Yeah, this proofs to me not all about Trigs are bad
Could possibly be the caffine prehaps?
Plant oils. All plant oils (fats) will damage cells. Now depending on cells you may end up with few months to few years of cell disability.
Caffeine damages nerve system. If you want to reverse some of that then try foods rich in ariginine. Like egg yolk, liver etc.
I'd love to see your data on those with familial hypercholesterolemia to see what keto does for them. I think this may be an unethical experiment since these patients have LDLs in the 300's. Maybe a disclaimer would be appropriate so those who are taking your word are increasing his or her risk of cardiovascular disease.
Well it would be an interesting experiment. I would presume TC/HDL ratio worsens as it does on keto.
@@TB1M1 Loaded language.
People can get a CAC score and Use that to determine their risk better than cholesterol levels that fluctuate.
Interesting comment, my LDL was persistently high at 300 when l started LCHF 3 years ago. Now its down to
I did the short pre-physical protocol plus giving up coffee. Either my doctor did not order the conventional lied panel with all of the other tests, or the lab simply failed to do them! What a total waste,
Hi Dave, I diary everything, BG each am. Carnivore Day 97. APO E 2 heterozygous. No tea coffee or dairy Day 37…. OMAD 16.
TG/HDL is not very useful to draw conclusions from. For you to be at high risk using that metric you need to have high cholesterol at baseline > 200mg/dl. If you have low cholesterol TG/HDL does not imply high risk! I suspect there is a threshold at which triglycerides starts ramping up artery disease some where over 150 mg/dl
www.ahajournals.org/doi/full/10.1161/01.cir.92.6.1430
Show me the mechanism.
First
Love this guy
Hi Dave,
To be honest I still can't make out what the heck you are talking about. I am concerned about cholesterol because I underwent triple bypass surgery.
I started on KETO / IF eight months ago, lost 23kg, 7ins of my waist, reversed my BP and diabetes. Now I have graduated to OMAD my BP and diabetes is better controlled.
Now what I understand is that once you are on LCHF your body has switched from glucose to fat as source of energy, every single cell in your body needs triglyceride. Can't understand why even bother about cholesterol as far as my bird brain reasons it is a non issue why so much fuss about cholesterol?
Have you had an NMR lipid profile done recently? Some keto dieters have very high numbers (myself) and their doc would try to put them on statins because conventional medicine dictates that's dangerous. He was trying to get to the bottom of this. Is high LDL-C an issue or not? What about LDL-P? Cholesterol seems to be more complex than we might have been taught to think
Rooben...Check out Nadir Mir Ali, a cardiologist TH-cam channel, he explains this and other issues very well!! He even used Dave's explanation, but with more visuals. Good luck!
Reckless and dangerous advice.
lol, found the butt hurt vegan
For big pharma profits