Learn to use KLIFS Database on Google Colab. A course of CADD

[@abubakarraja7605]

😊😊😊

[@Bioinformaticsinsights]

Thanks

[@Bioinformaticsinsights]

Thanks

[@priyankaahlawat1745]

Hi Sir.. can you please upload tutorial for covalent molecular docking using autodock

[@Bioinformaticsinsights]

@Priyanka, I have already uploaded tutorial on AutoDock Vina, both using on Google Colab and in offline setup. AutoDock and AutoDock Vina are developed by the same lab, and almost use the same procedures, though Vina is relatively bugs free than AutoDock.

[@priyankaahlawat1745]

@@Bioinformaticsinsights sir i wanted to ask that if the flexible and covalent docking are same or not

[@Bioinformaticsinsights]

@priyankaahlawat1745 these are different approaches. The opposite approach of flexible docking is rigid docking, while in covalent docking we focus on covalent bond formation between ligand and receptor, and it can be performed by a flexible or rigid way. Please read literature for further discrimination.
Regards

[@derivoid]

Sir, what do we do when our protein is not in KLIFS?

[@Bioinformaticsinsights]

Dear KLIFS contains only kinase proteins not all. I have already discussed some where in the video. It means you are not dealing Kinase - therefore you can skip this tutorial.