Thank u for your useful tutorial. I have a little query. What if the protein is not bound to a ligand in PDB, and i have to find out the binding site in a protein with a new organic ligand.
Dear Dr. Nisar, in that case you have to probe the active site residues first. Nowadays, too many trained models are present, like AlphaFold, Chai, and Boltz. It is better to test them. Also, you can pick these information from the literature.
An Info-riched lecture
Waleed sabar, Yar sar kujany da time nhe. :-)
Very nice classes.
Keep watching
Very good tutoial dr
Continue Please
Thanks @ES-yd1ze for the support and encouragement.
Thank u for your useful tutorial. I have a little query. What if the protein is not bound to a ligand in PDB, and i have to find out the binding site in a protein with a new organic ligand.
Dear Dr. Nisar, in that case you have to probe the active site residues first. Nowadays, too many trained models are present, like AlphaFold, Chai, and Boltz. It is better to test them. Also, you can pick these information from the literature.
@@Bioinformaticsinsights Thank you