At seems to me that every video I watch has different levels of detail on the same concept and the ones that express the most detail such as mentioning WHY certain things happen as opposed to "lipid just oxidises" and "A blood clot then forms" are the best ones. and I cannot learn and understand concepts that superficially. I have to know the details and this video does a good job of going past the details given in my specific lecture giving me a more understanding which means better chances of remembering! I am set with this. Thank you!
wfpb diet is the only thing that can cure almost all deseases of our rich societies,, mostly raw even better (vegsources on youtube,, many doctors explains in detail (dont think that much in detail,, but im too dumb to get it so i hope you can follow their explanations better then i can
This is brilliant. I've been searching for days for a clear explanation of this... sifting through text books, google and journal articles. In 6:05 minutes you have made it all click. Thank you.
Watched for the first time and u held my attention all the way through. Like your voice and animations. Will share with other nursing student. Not everyone can teach good video. Please release more.
I loved this video the animation and the perfect and simple explanation was made it very easy for me to study this topic. I really really wish you could make more such video with this type of clear and simple animations and explaination of o pathogenesis of other disease also it really help us students a lot to study. My teacher actually recommended this video.
That was brilliant. Thanks! I saw a photo of cholesterol building up so much that it formed sharp crystals underneath which then cut and burst through the endothelial lining.
This video helped me find the answer that I have been looking for the whole time. I even tried to look up but I could barely understand. For example, where do oxidized LDLs come from? Why there are macrophages in the tunca intima? I am so so grateful!!!!!
Tiến Nhật LDL and other lipoproteins can become oxidized through a number of ways. Reacting with ROS, glycation, binding to proteoglycans, ect. Oxidized LDL in the blood plasma isn’t an issue in this context. It’s only when it’s oxidized in the intima is it a problem. Monocytes will travel through the Endothelial into the intima and become macrophages. OxLDL being trapped in the intima triggers them to come into the intima.
Eating too much oxidized polyunsaturated fats, oxidation continues in the body. When ApoB receptors are damaged (by oxidation or glycation), the liver can't identify the LDL any longer, they keep circulating until they crash. To me this is a much more credible description than "too many LDL".
I just saw your video Sir, it was straight to the point I read the book and couldn't understand it. I took everything u said lmao. Thank you having a quiz on Wednesday for CAD
Could you do a video on what steps to take to prevent or minimize initiating the process in the first place? This is a worry of us - the senior group. Your explanation is easy to understand- hence the request for you. Thank you so much.
switch to a low carb diet. This way you minimise the amount of glucose in your system which damages endothelial cells. There are many, many other reasons why a low/no carb diet is beneficial for your health. I really do encourage everyone to do some research on this. Its a very interesting rabbit hole to go down.
There seems to be so little focus in these similar models on the initial irritation and damage to delicate arterial walls. High BG, HT, etc are mentioned but surely the number of irritating sources are much higher in modern living and interact- so the blood flowing through arteries today is like a sewer from the thousands of industrial chemicals in our foods, air, personal products, and inactive ingredients in pharmaceuticals. It would be helpful if these types of models connected the problem with the upstream causes from our industries. The model is very clear about what happens if we dont turn off the poison coming into our bodies. Thanks
Hyperinsulinemia ( Chronically high blood sugar levels) has been identified as the culprit of the damage to arterial walls... What follows, as in the video, is mostly a collateral damage of Syndrome X...
This is so helpful and explains fantastically what I struggled to understand from my powerpoint presentation. Would you be able to tell me how collagen plays a part here? According to my slides, smooth muscle cell proliferation occurs due to further endothelial damage from oxidative stress from fatty streaks - this then leads to collagen production . Would I be right in saying the collagen forms over the hardened plaque in this instance, and the thrombus attaches on top of it? Or is collagen part of what forms the plaque? Any help would be appreciated! :)
Where does the atherosclerotic lesion come in? I'm a bit confused about the difference between the lesion and the plaque. Thanks for the video though, a true life saver :)
It’s the same thing. The lesion or plaque may change over time with disease progression. For example as calcium is added to the atherosclerotic plaque it becomes more rigid.
At seems to me that every video I watch has different levels of detail on the same concept and the ones that express the most detail such as mentioning WHY certain things happen as opposed to "lipid just oxidises" and "A blood clot then forms" are the best ones. and I cannot learn and understand concepts that superficially. I have to know the details and this video does a good job of going past the details given in my specific lecture giving me a more understanding which means better chances of remembering! I am set with this. Thank you!
wfpb diet is the only thing that can cure almost all deseases of our rich societies,, mostly raw even better (vegsources on youtube,, many doctors explains in detail (dont think that much in detail,, but im too dumb to get it so i hope you can follow their explanations better then i can
🙏🙏🙏😊
Who tf picks that kind of username? “ Jihad”.
@@adnertga6559 what's wrong with it?
@@alexx_93 Take a wild guess
I always come back to this video whenever I forget the visuals of this pathogenesis. It is so simple and well created! Thank you!
Same same watched it in 2nd yr for pathology now 2yrs later for medicine
Concise and perfectly animated and narrated, THANK YOU for this incredibly helpful video!!!
If it wasnt for this video, i would never understand atherosclerosis, thank you very much for telling the story of atherosclerosis
The video was amazing!!!! Will def rewatch a few more times in preparation for my patho exam! Thank you!!
Good job, sir. I wish my teacher could explain it like you did.
I know right......
This man's narration is at the perfect speed to really understand this!
This is brilliant. I've been searching for days for a clear explanation of this... sifting through text books, google and journal articles. In 6:05 minutes you have made it all click. Thank you.
That’s very kind thank you very much
This video is so amazing. It makes the concept so easy to grasp. Thank you so much for this masterpiece
well done bro ,I watched 1 hour lecture my doctor and your video only 6 min soooo help me to understant thank you❤️❤️❤️
Watched for the first time and u held my attention all the way through. Like your voice and animations. Will share with other nursing student. Not everyone can teach good video. Please release more.
I loved this video the animation and the perfect and simple explanation was made it very easy for me to study this topic.
I really really wish you could make more such video with this type of clear and simple animations and explaination of o pathogenesis of other disease also it really help us students a lot to study. My teacher actually recommended this video.
Brilliant thank you, I have been reading a lot but it just didn't make sense to me, this helps so much being able to see it. Thank you
Glad it helped!
Glad it helped!
Thank you for such a detailed informative video! best one i've watched on the topic. Subscribed!
My exam is in an hour. Thank you for simplifying this and filling in my knowledge gaps.
Best of luck!
Saved my 30 mins of reading thru the book. Thank you
Awesome thanks!
This was so helpful! So on point and easily understood. Thank you so much!
So that’s what my professor meant 😅
Simple , clear with intelligence way 👌
Thank you soo much sir ❤️ lot's of love from India
That was brilliant. Thanks! I saw a photo of cholesterol building up so much that it formed sharp crystals underneath which then cut and burst through the endothelial lining.
wouldn't it be ApoB instead of LDL?
This video helped me find the answer that I have been looking for the whole time. I even tried to look up but I could barely understand. For example, where do oxidized LDLs come from? Why there are macrophages in the tunca intima?
I am so so grateful!!!!!
Tiến Nhật LDL and other lipoproteins can become oxidized through a number of ways. Reacting with ROS, glycation, binding to proteoglycans, ect. Oxidized LDL in the blood plasma isn’t an issue in this context. It’s only when it’s oxidized in the intima is it a problem. Monocytes will travel through the Endothelial into the intima and become macrophages. OxLDL being trapped in the intima triggers them to come into the intima.
Eating too much oxidized polyunsaturated fats, oxidation continues in the body. When ApoB receptors are damaged (by oxidation or glycation), the liver can't identify the LDL any longer, they keep circulating until they crash.
To me this is a much more credible description than "too many LDL".
I clicked like on an educational video for the first time. What a year of change.
Awesome best of luck in your pursuit of knowledge
Omg! This is absolutely amazing! High five ✋
Thanks sir for explaining the concept in a very nice way ❤️
awesome illustration!! my brain was able to connect all of the dots with the help of the animations
The best explaination of ATS formation ive ever watched !
So succinct. Great video
this is just so good, thank you!
Best ilustration from youtube imo
I just saw your video Sir, it was straight to the point I read the book and couldn't understand it. I took everything u said lmao.
Thank you having a quiz on Wednesday for CAD
Very well explained. Thanks.
Brilliant explanation, thank you!!
Thanks,my lecturer couldn't even dream to explain it like this.😂
I can't believe this doesn't have more views
TOTALLY AGREE
Excellent. Watched this with my daughter, and it has motivated me not to miss taking my cholesterol medication.
Excellent, that’s great
You are amazing! Your videos are incredibly helpful. Such smooth voice and fantastic animation!
Thanks, that is so kind. I really appreciate it :)
Perfect! Just perfect!
😭. Thank you. My prof doesn't do visuals. He does very word dense and lengthy ppt lectures.
Thank you so much! This really helped me understand the concept before my exam. 🤗
Glad it was helpful. Hope you ace your exam
This was so great!!!! thank you
Those summary quizzes are the best idea for an educational medical lectures video. Hope to see more of those in the future
Thanks for the feedback; glad it was helpful
Thank you very much
Excellent Video.
Thanks so, so much for this!!
Thank you so much! This is such quality material you’re presenting.
Subscribed! Look forward to seeing more of your videos.
Thanks, very much appreciated
Thank you so much ! This made me understanding what my lecturer has been teaching all the while 😂
Thank you your explanation was detailed and very helpful.
Thank you sir.
Thanks, it was really helpful!!
Glad to hear that!
Amazing 😍
Thank you so much!!
Wow never understood it so well! Thankyou for this!!
OMG, this is PERFECT !
Very very useful animation. Keep doing more videos sir❤
Sure 👍
thank you it was very good explanation
You are welcome!
Superb ❤
Thank you so much ❤
Wonderful explanation
Could you do a video on what steps to take to prevent or minimize initiating the process in the first place? This is a worry of us - the senior group. Your explanation is easy to understand- hence the request for you. Thank you so much.
switch to a low carb diet. This way you minimise the amount of glucose in your system which damages endothelial cells. There are many, many other reasons why a low/no carb diet is beneficial for your health. I really do encourage everyone to do some research on this. Its a very interesting rabbit hole to go down.
Smoking is also a huge factor, if you smoke please quit
@@infj.creature Thank you for your reply. I dont smoke so that is somewhat reassuring.
Good job 👏
There seems to be so little focus in these similar models on the initial irritation and damage to delicate arterial walls. High BG, HT, etc are mentioned but surely the number of irritating sources are much higher in modern living and interact- so the blood flowing through arteries today is like a sewer from the thousands of industrial chemicals in our foods, air, personal products, and inactive ingredients in pharmaceuticals. It would be helpful if these types of models connected the problem with the upstream causes from our industries. The model is very clear about what happens if we dont turn off the poison coming into our bodies. Thanks
Brilliant Video Thank you!
Hyperinsulinemia ( Chronically high blood sugar levels) has been identified as the culprit of the damage to arterial walls... What follows, as in the video, is mostly a collateral damage of Syndrome X...
Best explanation, easy to understand thankyou so much
That was an awesome video! Thank you
Very good explanation and animation. thank you
You are welcome!
Thank you so much, You Expalined like a pro..🔥
Amazing! It cleared up the concept very well. :)
Fantastic video it really helped explain Atherosclerosis to me!
Great glad it was helpful
Tqu sir love from India
I looooooove your content thank yoooooou I'm so happy that we have you
I'm here again
Thank you for that! This is very informative.
Can we get this man to 100,000 subscribers? This 6 minute video explained 50 slides in my lecture.
Thank you for clarifying the foam cells, I thought they ate one lipid and died.
Thanks, thats great feedback
THIS IS VERY INFORMATIVE. THANK YOU!
thank you!
tysm! this was easy to follow
Such a good explanation
Thank you very much for this video
Excellent.
Thank you
Thanks 🙏🏼
thanks, way better than Khans
Thanks so much
Thank you. Very good explanation
Glad it was helpful!
My favourite explanation
Thank you so much sir..
❤great video thank you
Sir, I salute you.
Perfect explanation ✨
very good explanation
Insulin resistance and glycation.
If you eat fat, don't eat carbs. Or...if you eat carbs don't eat fats.
Great explanation , thank you 😊
A very good job guys ....just loved the video ❤️❤️
Awesome, thank you very much
This is so helpful and explains fantastically what I struggled to understand from my powerpoint presentation. Would you be able to tell me how collagen plays a part here? According to my slides, smooth muscle cell proliferation occurs due to further endothelial damage from oxidative stress from fatty streaks - this then leads to collagen production . Would I be right in saying the collagen forms over the hardened plaque in this instance, and the thrombus attaches on top of it? Or is collagen part of what forms the plaque? Any help would be appreciated! :)
the proliferation of smooth muscles and collagen is also caused by PDGF produced by the platelets
Thank you sir
new subscriber💙✨
Amazing explanation 👍🏻👍🏻
Amazing lacturee
Where does the atherosclerotic lesion come in? I'm a bit confused about the difference between the lesion and the plaque. Thanks for the video though, a true life saver :)
It’s the same thing. The lesion or plaque may change over time with disease progression. For example as calcium is added to the atherosclerotic plaque it becomes more rigid.