I see a couple issues with this video. First, it's missing what happens to the lagging strand. The DNA Polymerase enzyme can only add the new DNA from the 3 prime end to the 5 prime end. It has to go the opposite direction on the lagging strand. (That would mean we are missing Okazaki fragments and the adding and removing of the Primer). Also, the separation of the DNA causes tension at the twisted end and there is an enzyme called DNA Gyrase to fix that. Without it, the Helicase couldn't separate the DNA all the way.
These enzymes are also missing: The SSB proteins which protects the strand from degradation and prevents it from pairing. Ligase enzyme which joins the okazaki fragments. .
It would've been good if you explained how the second strand is duplicated as it's not the same as the first... which could be misleading to those that do not know that... for those that need that information, keep searching the videos dudes for more accurate info.
It’s a good video but it isn’t detailed enough, there is no mention of Okazaki fragments, the 5 prime to 3 prime way the dna polymerase has to go and enzymes like ligase, topoisomerase and more
Your videos are fantastic!! We consider them the best videos on this topic. Can you plz guide us which software do you use for generation of these videos
those don't exist.. neither do okazaki fragments.... apparently serious answer tho, I think this just for like introductory biology, like high school level
Thank you so much for this explanation.. though it covered the concept but I needed in a more deeper way like of you have mentioned about replication fork ,ssbp,other more enzymes involved etc.. Btw the animation & visualisation was good ✨
No, this happens in Interphase before mitosis and meiosis. Prophase is part of the cell division
11 หลายเดือนก่อน
The reason "why" the double helix coils down, is because of the "movements of energy"! AGCT is a scientific name of the strands, but similarly, these strands "commit" to energies, that are not included in these studies, because: SCIENCE is based on "hypothesis", and they lack the "spiritual side" of the making! Therefore, "we" keep on studying with names, and forget to think! ENERGYS.....these are the "sublime" units that build up life, itself! - Yours, CLEOPATRA 2000+
These is the only video on youtube which explain DNA replication in a great and proper way
Look further, it's very lacking in some necessary details
Wonderful work! This series deserves far more views than it seems to have.
Agree with you
I see a couple issues with this video. First, it's missing what happens to the lagging strand. The DNA Polymerase enzyme can only add the new DNA from the 3 prime end to the 5 prime end. It has to go the opposite direction on the lagging strand. (That would mean we are missing Okazaki fragments and the adding and removing of the Primer). Also, the separation of the DNA causes tension at the twisted end and there is an enzyme called DNA Gyrase to fix that. Without it, the Helicase couldn't separate the DNA all the way.
These enzymes are also missing:
The SSB proteins which protects the strand from degradation and prevents it from pairing.
Ligase enzyme which joins the okazaki fragments. .
It would've been good if you explained how the second strand is duplicated as it's not the same as the first... which could be misleading to those that do not know that... for those that need that information, keep searching the videos dudes for more accurate info.
@@Bub-n-Luci the process is different in how each strand is produced, one is continuous duplication, the other is done in stages
He also didn't mention SSBP, toposiomerase, DNA primase ligase function along with okazaki fragments lagging strand and leading strand
Exactly
*Nucleus Medical Media Thank You So Much ! You're Blessing for Us* 🤠
thank you for explaining in a simpler but yet in a very clear and educative way.💯
Glad it was helpful!
Thank you soooooo much. I don't know how I could understand biology without your videos ❤❤❤❤❤
Best animated tutorial I never watched before like this
Finally understood how it's replicated. Very clear animation. Super 👍
It’s a good video but it isn’t detailed enough, there is no mention of Okazaki fragments, the 5 prime to 3 prime way the dna polymerase has to go and enzymes like ligase, topoisomerase and more
I'd be very grateful if you'd kindly considering making this sort of videos covering the whole A level syllabus!
Thank you!
Thanks so much help me for exam very good explanation
Best visual explanation, I have ever seen, very well explained. Thanks
It would be good if you suggested the right order of watching the videos you have made. Thank you
Watching this video for my biology high school final exams
This channel is super helpful
@@jakegordz101 it's lacking vital information, it this is for your exam search further, the second stand is duplicated differently
@@soulfuljuiciness thanks but it covers what's in my syllabus
@@jakegordz101 I tutor biochem, this video doesn't include how the second strand is duplicated, just make sure you don't need to know that then
@@soulfuljuiciness I'm 100% sure I don't but thanks very much
The way you explain it is so great. Thanks a lot
This channel is the best
By far the most exquisite video explaining this. So awesome! Big shout out to the creator!
Unbelievable!! Now, I know where the nucleotides that bind to the template come from!! THANK YOU!!!!!
this vid was ok, could definitely go more into depth though, it doesn't even touch on the more important aspects of DNA replication
Thank youthese videos have helped me so much!!
Thanks sir for Very impressive and clear teaching
the primer is a sequence of nucleotides after the helicase places the primer and then the DNA polymerase adds the nucleotides
Underrated guy...💀
WoW best animatic video in this topic to clear your base .💙🙏
Your videos are fantastic!! We consider them the best videos on this topic. Can you plz guide us which software do you use for generation of these videos
Great video but, what about de SSB proteins? When the helicase cuts the hydrogen bonds, DNA needs a complex which maintain each strand separated.
This is the best video I have ever seen about DNA replication. Kudos!
Thank you for this video. I didn't understand it when I read it in my textbook, but now I do!
Okazaki fragments?
Aap kaha se hai sir which city
what about leading and lagging strand? primase and ligase?
those don't exist.. neither do okazaki fragments.... apparently
serious answer tho, I think this just for like introductory biology, like high school level
Forever Thanks.
Well explained
Where is topoisomerase..?!
Please make another associated video about how mutation occur during DNA replication.
amazing! thank you.
Such a life saver❤❤
Hi! Great video! I cannot find your translation video, though. :)
Wow!!! thanks a lot.I am from Bangladesh 🥰🥰
Thanks
Very useful video👍👍👍👍👍
Thank you very much sir
Thank you so much for this explanation.. though it covered the concept but
I needed in a more deeper way like of you have mentioned about replication fork ,ssbp,other more enzymes involved etc..
Btw the animation & visualisation was good ✨
Thank you so much!!
Thank you
Can you make more videos plssss
What does helicase and polymerase mean?
Screw the lagging strand
why didn't u talk about DNA ligase
Good explain .......
impressive kudos
Nice info 👍
Keep it up 👍
Thank you sooooo much 💐💐💐
Tnx so much
Please upload videos more frequantly
we want more videos and quizzes based on biology ncert 🙏 ❤️ Love from India
Thanks!
Why they dont teach us with védios like that it's just very clear and simple ❤
Thank u sir❤
That was the thing that was trubbling that how the cell maintane the no. Of cromosome thankyou ❤😊
my science teacher said this was good
Does this happens at prophase stage of mitosis and meiosi?
yes! this is the process dna goes through to replicate for both mitosis and meiosis
No, this happens in Interphase before mitosis and meiosis.
Prophase is part of the cell division
The reason "why" the double helix coils down, is because of the "movements of energy"! AGCT is a scientific name of the strands, but similarly, these strands "commit" to energies, that are not included in these studies, because: SCIENCE is based on "hypothesis", and they lack the "spiritual side" of the making! Therefore, "we" keep on studying with names, and forget to think! ENERGYS.....these are the "sublime" units that build up life, itself! - Yours, CLEOPATRA 2000+
Wth
DNA is the condensed network in the form of chromosomes so why chromosomes are not divided in S-phase?
Chromosomes divide in the G1phase
No mention of primase or ligase, or the flow of polymerase from 3' to 5'.
3.5/5.
Disappointing!
All your other videos have been fantastic!
Right! He doesn’t even talk about leading or lagging strands and the Okazaki fragments
What can I say exept THANK YOU
Anyone got a summary of the vid
greatttttt
❤❤❤❤
Thanks🙏🙏🙏🙏🙏🙏🧨🧨🧨🧨🧨🎄
salam seko jawa tengah lek
Ok thanks vai 🆗🇧🇩
Ok maninho isto já não ta a ter piada, a salomé não me ensinou nada destas brincadeirinhas…. Abraço!
Where is the RNA??
Ribonuclic acid
You are so cool UwU 🎉
Where free nucleotide come from
they're floating freely in the nucleus
سبحان الله ♥️😍
Such a life saver❤❤