Webinar | Precision Medicine in Lung Diseases: New Developments

Join us for a webinar focused on tissue remodeling, inflammation and biomarkers for pulmonary diseases. Our panel of experts will shed light on the tissue changes occurring in pulmonary diseases including idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease, and how this is affected by the intricate interplay between fibroblasts, epithelial cells, and immune cells.
The speakers will take you on a journey from discovering novel biomarkers to implementing them in clinical trials and clinical practice. They will discuss why blood-based biomarkers are needed for pulmonary diseases, and how biomarkers of ECM remodeling and immune cell activity may aid in the identification of novel endotypes and improvement of drug development.
Some of the talking points include:
• How changes in the composition of the ECM in lung fibrosis impact cellular function
• How the ECM organization changes in lung fibrosis, and implications for disease-driving processes
• How matrix stiffness is altered in fibrosis and the cellular responses to these changes
• How the above changes can be incorporated in model systems in vitro to expand our understanding of disease underlying mechanisms
0:00 Intro
4:48 Dr. Janette Burgess - Extracellular Matrix is an Active Agent in Lung Fibrosis
32:07 Dr. Gisli Jenkins - The Role of Alveolar Epithelium in Fibrotic Matrix
52:50 Dr. Jannie Sand - Prognostic and Pharmacodynamic Biomarkers of ECM Remodeling
1:14:30 General Discussion and Q&A
#ipf #copd #webinar #drugdevelopment #fibrosis