I’m a new person taking Kesimpta. I’m doing better than I have in 10 years. It’s remarkable! Heat intolerance, fatigue, cognitive issues and energy much improved. And super easy dosing. Many in group doing better than when on O. I’d love to know why!
I think, personally, it's just less load for our bodies. Like, carrying 100lbs all at once vs carrying 20lbs 5 times. It's why I went with K, it just makes more sense
I know from experience why some of the people on Kesimpta may be doing better than those on Ocravus: I'm on Ocravus, and around 1.5 months before my infusion, I guess my wayward immune system starts coming back to life and I feel like 💩. After that, it's ANOTHER month till I get back to myself. I guess that this phenomenon wouldn't occur if my doses of B cell depleater were given regularly, once a month. Makes me consider switching to Kesimpta as a solution to the "crap gap", because Lord knows my new neurologist has been turned down by the insurance for anything else she's tried to prescribe. Food for thought. Thanks for asking.
@kkaci5 That's great to hear! I just started Kesimpta and will take my third shot of the initiating dose series tomorrow. Thank you so much for sharing!
Glad it is working well for you! I am just switching from Tysabri to Kesimpta and am hoping it also works well for me. Thanks for sharing your experience and best to you 💕
My mother has been treated with Rituximab and chemotherapy when she was 78 and had Non-Hodgkin (cancer). After the chemo she still was treated with Rituximab for a period of time. She had no side effects of this drug. Maybe this helps to get a more positive opinion about this succesfull treatment with this drug, bc she is now 92 years old.😉
Thanks, Dr. Boster! Very informative as always. I appreciate these videos. I’ve been on Ocrevus five years, but will be de-escalating or stopping. My compromised immune system, including very low IgG levels has caught up with me. In the hospital right now for the third time this month with severe covid pneumonia and organizing pneumonia that keeps progressing. I am very grateful for the five years on Ocrevus. Other than this final infection, it has been a wonderful DMT for me. I don’t at all want to scare people. I would do it all over in a heartbeat.
I’m on Ocrevus infusions. It’s a day in out patients here in Perth Western Australia. I go in for the day, every 6 months. I’m one of the lucky ones. It’s my 1st meditation and we have seen lesion shrinkage. Absolutely fabulous results! 😊
There’s a rumour swirling on one of the Facebook support groups for Kesimpta that taking probiotics is contraindicated for anyone taking a B Cell depleting DMT. Meanwhile, probiotics seem to be recommended generally for those with MS for improving the microbiome. I would love to know your thoughts on the issue.
I am in my 70's and was diagnosed late onset PPMS and was put on Ocrevus with great results, no new lesions, shrinkage of existing lesions, and no problems of secondary infections of any kind. Blood tests were always fine. Dr. retired, new doctor will not let me continue Ocrevus because of my advanced age. Furthermore, trying to find a neurologist willing to even speak with me about returning to Ocrevus infusions is impossible. I have called multiple doctors with the same response - not taking new patients (never mentioned but I'm sure a deciding factor, age). I am now beginning to see accelerated deterioration in my walking and strength. Last MRI showed the possible beginning of new a new lesion. Angry, doesn't begin to describe my current outlook. Sorry for the rant. Wish I lived in Ohio!
Who that is unbelievable that 0 is was working so well and your doctors won’t continue with what’s working. I was well take O and it working just fine for me. Maybe you could find a doctor out in a different area from where you live. I hope you get the O you need maybe try contacting your Medicare and your insurance provider and see if they can help you. I wish you well and prayers.
I hope you have success with Kesimpta! I have been on it for 1-1/2 years since my diagnosis. Thankfully, I can still do most everything I want to do from before diagnosis. I was diagnosed at 54. I do try to prioritize sleep and exercise and eat well even though I love sweets! Cutting out dairy & much gluten makes me feel better. I don't really drink alcohol much anymore and it's good. Lots o & lots of water and yoga too help me. Also, very important to keep stress as low as possible. love from Colo
They are doing a study in Denmark compering the ocrevus vs rituximab, blind study you get one of the 2 without knowing witch one and doctors don't know either. 1/3 get rituximab and 2/3 get ocrevus. Think this is because then people can convince themselves it is most likely the get ocrevus. I was not accepted in because I didn't check all boxes for the study. So the put me on kesimpta.
Wow I've got frickn mouse protein in my system 😢smh man this sooo gross I've got progressive multiple sclerosis had absolutely no idea what I was being injected every six months
This is appropriate to wake up to, I just spent most of last week in hospital after a really bad reaction to Kesimpta and was told I can no longer take it. I’ve been wondering if I’ll be able to take any of the B cell depleters or if I’ll have to switch to a different type.
Thanks Dr. B! I've been on Ocrevus for a year now and it's been great for me. I got my second full infusion 10 days ago at the faster rate, but overall still took 4 hours. All of my symptoms went silent within a few months after the first infusions and I didn't have much fatigue during the "crap gap" before my last infusion (I did before the one 6 months ago). If BTKs show similar efficacy and safety, I'd switch as a long term plan to restore my full immune system and eliminate the infection risk factors. Can you post a video discussing the current state and prospects of BTK inhibitors?
Kesimpta holds my cd19 level at 0, but ocrevus only held the number at 0 for around 4 months, so it wasn’t powerful enough I’m assuming. It seems I need the monthly treatment regiment.
All my MS symptoms were much worse in the days after my 2nd half dose of Ocrevus. Should I expect this every time I get Ocrevus? It's very difficult to deal with.
Ocrevus that’s what my neurologist put me on when I was diagnosed in 2020 because I was positive for JC. O has worked wonders for me. I wish you well…!
Very timely video! Thank you! I had been on Ocrevus for 3 years. Dose changed to every 5 months due to crap gap. Thought I would try Kesimpta, because it was a B cell depleter and seemed so much easier. Big mistake. Feel like I’ve fallen into the crap gap continuously for the past few months. I’m switching back to Ocrevus next month. I know these meds have not been studied head-to-head, but has your anecdotal experience been that patients do about the same? Thanks again!
RE: colitis - my guess is that it's not as uncommon as stated. keep in mind that no IBD patients were a part of the Kesimpta (another CD20 antibody) clinical trials. not only does ocrevus now have a warning (thankfully) but Therapeutic Advances in Neurological Disorders published guidelines for treating MS and other autoimmune disorders in 2021 specifically stating to avoid cd20 antibodies for those with IBD. I spent the last eight weeks in pure hell because of that contraindication. definitely not worth it, more neuros need to understand the risks for their patients that have IBD. I know that wasn't the original question. I think the original question was talking about the risk without IBD, but I can't help make this point.
I’m about to start on Briumvi. I’ve been on Vumerity and have a new lesion and 2 old lesions have grown significantly in the last year so - we’re changing meds. Ugh. Here’s hoping. 🤞🏻
Next month is my second dose of ocrevus, but I feel so tired these days. Is this normal? Will these symptoms disappear after taking the medication? Thank you
Ty for letting explaining this! Helps alot! Question: how about surgeries and taking these meds? I ask because I'm taking Kesimpta and I probably need a hysterectomy
I was on Ocrevus for 2 years and went into secondary progressive MS, switched to Kesimpta. Had to miss 3 months of it due to an initial hospitalization for an MS flare with a fever, they treated the fever as if there was an infection, as I would expect (I’ve been a nurse for 30 years), 2 more hospitalizations after that because the initial hospitalization they gave me strong antibiotics which caused CDif, then I had a rebound case of it which really messed with my MS. Been on kesimpta for about 1 1/2 years, this was my first big flare. I know Ocrevus and kesimpta are the newest meds out there . Are there any new meds, that show promise, coming soon for secondary progressive?
So sorry... Oh my! You are going through a lot! I got side effects + rate reactions from every DMT I tried before Ocrevus became available. Now I'm thinking I'm better with my original MS dx vs. all the potential side effects of new meds.
If Rituxan is a cd20 depleter, then why isn’t it checked in blood work? My cd19 is low (zero), but cd20 isn’t even checked. Cd16, cd56 above normal. Others normal and IGG and IgM normal. It seems strange these other CD types are checked, but not cd20. Is there a reason for this? I don’t care if answer is “nerdy.” 😂
Hey Doc! Urgent, important QUESTION: Are you going to address the unspoken but obvious change you've made??? The big metal Brain Games toy over your shoulder looks like an interesting conversation piece...😉 Excellent topic!!
I took my first Briumv B shot and had minimal side effects like chest tightness, muscle soreness. And 10 days into it, I am feeling extremely tired, fatigued, and even more muscle soreness, but I noticed it wears off the more I rest. Then the full 450 mg dose is in two weeks. 🙏🏼❤️
My medical insurance has been switching to the B-cell depletors. I asked my doctor if there was any difference in efficacy between Ocrevus and Rituxan and he didn't think there was. He seems to think Ocrevus was developed to cash in on the success of rituximab, which is much cheaper, being a generic.
Is funny you made this video, I was just thinking about this very subject, our blood tests. My MS sister or brother had my same thoughts it would seem! Thank you Dr. B 🧡🧡🧡
I will be receiving the Riabrii in a week or so. I have received Rutuxin but that was before the pandemic. Out of caution I did not receive any since 2020. I am 67 y/o and what my neurologist described as “ an outlier). I as diagnosed at the very beginning of 2018.
What do you think about the clinical trial that suggesting that N-acetylglucosamine restores neurological function in Multiple Sclerosis patients? Would be really interesting to cover this as well
Thank you for these very informative videos. My son (35 years old) was diagnosed 2 years ago with MS. Ocrevus has been a miracle. He has had no flare ups while on it. Previous medications did not work. At his last visit his neurologist said if his anitbodies drop lower, he will have to come off Ocrevus. She did not tell us about the infusion of IvIg antibodies so he could stay on it. We are very scared of trying a different medication, as others did not work. Should we find a new doctor in light of her not giving us all the choices you explained?
Question: if lemtrada is an IRT by killing b and T cells, such that only 2-3 doses are needed in most patients, why are the B cell depleters not also considered an IRT, such that they need to be taken indefinitely? What’s the difference?
I don’t know but Lemtrada is the most badass treatment In my Drs opinion(The Dr Aaron Boster 😊) Ocrevus and Lemtrada have had the best patient results. Hands down. I’m at 8 years of no treatment after doing Lemtrada No new damage of any kind. After 20 years of progressive disease course, I’m officially in remission, 5 years of no treatment and no disease progression
Hi Aaron, at a later Q and A session, could you address Ocrevus infusion times. I am on the IV drip for approx 8 hours because my body can only tolerate a full doze at a certain speed. I get dizzy, nauseous and have blinding headache despite having taken pain relief and an antihistamine before the infusion as well hydrating and eating throughout the process. Is this something I should be concerned about? Does it mean I am not tolerating through drug? I had a similar reaction with Rituximab.
I have MS, Trigeminal Neuralgia, Chiari Malformation (Surgery 2012) and Addisons Disease. i had plasmapheresis to start. Then multiple hospital stays for Soli-Medrol within the last year, i was on Tysabri for 8 months & continued to develop lesions. I just had round 2 of Ocrevus & im Praying it works..I went from being at the gym to in a wheelchair within a year. 💜
(From Montreal) Hello Aaron. I'm on Ocrevus infusion (every 6 months). I would like to know why I must wait 4 and a half month after the infusion, and 1 before the next one, to receive a vaccine. And thanks so much for your videos and such useful information :)
I had this question as well and what I was told pertains to the the actual B-cells. Most vaccines function from a B cell response, meaning that the dead virus that's injected via vaccine needs B cells to generate antibodies against that virus. So when you are taking a B cell killing medication, you don't have the B cells in your system to create the antibodies, meaning the virus has a lower efficacy. I'm on Ocrevus as well and this was the simple answer and understanding I have of the situation. Hope this helps!
My neurologist has asked me to research and consider the bi annual Ocrevus infusion, after a recent MRI shows two new lesions on my spine since the last MRI three years ago. Looking on Google, the good, the bad and the ugly has become very confusing. For the most part it seems to have some very nasty side effects - which is a bit disconcerting. I’m currently taking a daily Gilenya capsule which has been very effective in stopping the yearly relapses I was having while on daily Copaxone injections (and a far more pleasant way to fight MS). With Gilenya I’ve only had one relapse in several years and was surprised to hear of the new lesions. Could you please share your valuable experience with what to expect and the scenarios you have witnessed. Thank you for all you informative videos, it’s wonderful to hear your no nonsense and learned opinions. ❤
@@ecarlson4987no it’s not. I’ve been on 5 DMTs and failed at them all but Lemtrada has me at over 8 years. With no treatment. Since 3 days at the end of year 1
Hi from Israel as usual interesting data I hope to have more information about taking vaccinces during taking treatment to theMS especially on Tysabri and Ocrevus thanks what is the best time to get them
I’m a new person taking Kesimpta. I’m doing better than I have in 10 years. It’s remarkable! Heat intolerance, fatigue, cognitive issues and energy much improved. And super easy dosing. Many in group doing better than when on O. I’d love to know why!
I think, personally, it's just less load for our bodies. Like, carrying 100lbs all at once vs carrying 20lbs 5 times. It's why I went with K, it just makes more sense
I know from experience why some of the people on Kesimpta may be doing better than those on Ocravus: I'm on Ocravus, and around 1.5 months before my infusion, I guess my wayward immune system starts coming back to life and I feel like 💩. After that, it's ANOTHER month till I get back to myself. I guess that this phenomenon wouldn't occur if my doses of B cell depleater were given regularly, once a month. Makes me consider switching to Kesimpta as a solution to the "crap gap", because Lord knows my new neurologist has been turned down by the insurance for anything else she's tried to prescribe. Food for thought. Thanks for asking.
@kkaci5 That's great to hear! I just started Kesimpta and will take my third shot of the initiating dose series tomorrow. Thank you so much for sharing!
Glad it is working well for you! I am just switching from Tysabri to Kesimpta and am hoping it also works well for me. Thanks for sharing your experience and best to you 💕
@atanamorell2 hey hope it works out well for you. May I ask what made you switch from Tsyabri from Kseimpta?
My mother has been treated with Rituximab and chemotherapy when she was 78 and had Non-Hodgkin (cancer). After the chemo she still was treated with Rituximab for a period of time. She had no side effects of this drug. Maybe this helps to get a more positive opinion about this succesfull treatment with this drug, bc she is now 92 years old.😉
Thanks for sharing this with us! I am glad your mom had positive results! May she continue to live a good life! Blessings!
Another perfect dose of highly relevant and useful information. Thank You very much, Dr.Boster
Thanks, Dr. Boster! Very informative as always. I appreciate these videos.
I’ve been on Ocrevus five years, but will be de-escalating or stopping. My compromised immune system, including very low IgG levels has caught up with me. In the hospital right now for the third time this month with severe covid pneumonia and organizing pneumonia that keeps progressing.
I am very grateful for the five years on Ocrevus. Other than this final infection, it has been a wonderful DMT for me.
I don’t at all want to scare people. I would do it all over in a heartbeat.
I’m on my way to a full recovery now. Yay!
I’m on Ocrevus infusions. It’s a day in out patients here in Perth Western Australia. I go in for the day, every 6 months. I’m one of the lucky ones. It’s my 1st meditation and we have seen lesion shrinkage. Absolutely fabulous results! 😊
I am in Perth too and use Kesipmta. Very easy to administration and super effective it is also on PBS
Can you please make a video on the -so called- "inverse vaccine" which is under trial..?
was about to ask the same thing would love to hear his thoughts :)
Will I turn into Mighty Mouse?
😆 thanks, made me laugh
😂
There’s a rumour swirling on one of the Facebook support groups for Kesimpta that taking probiotics is contraindicated for anyone taking a B Cell depleting DMT. Meanwhile, probiotics seem to be recommended generally for those with MS for improving the microbiome. I would love to know your thoughts on the issue.
what is their reasoning? considering there are more bacteria in your gut than cells in your body, therefore this seems like a rumour.
On kesimpta and this video just reminded me I really need to do my blood tests! going next week.
Mavenclad depletes B and T correct? Only 2 times a year.Have you had any good luck with this?
I'm waiting to move over to Ofatumumab. Can't come quick enough.
It's great
I am in my 70's and was diagnosed late onset PPMS and was put on Ocrevus with great results, no new lesions, shrinkage of existing lesions, and no problems of secondary infections of any kind. Blood tests were always fine. Dr. retired, new doctor will not let me continue Ocrevus because of my advanced age. Furthermore, trying to find a neurologist willing to even speak with me about returning to Ocrevus infusions is impossible. I have called multiple doctors with the same response - not taking new patients (never mentioned but I'm sure a deciding factor, age). I am now beginning to see accelerated deterioration in my walking and strength. Last MRI showed the possible beginning of new a new lesion. Angry, doesn't begin to describe my current outlook.
Sorry for the rant. Wish I lived in Ohio!
Who that is unbelievable that 0 is was working so well and your doctors won’t continue with what’s working. I was well take O and it working just fine for me. Maybe you could find a doctor out in a different area from where you live. I hope you get the O you need maybe try contacting your Medicare and your insurance provider and see if they can help you. I wish you well and prayers.
That's horrible. It's ageist and cruel. I am so sorry this is happening to you. It's inexcusable. Rant away! 🫂❤
Thank you, Dr. Boster~😎
I’m scared because I’m jvc positive and neuro recommends Briumvi ,PML risk?
I just started Kesimpta just a little over 3 weeks ago. I'm already seeing a big difference!
I hope you have success with Kesimpta! I have been on it for 1-1/2 years since my diagnosis. Thankfully, I can still do most everything I want to do from before diagnosis. I was diagnosed at 54. I do try to prioritize sleep and exercise and eat well even though I love sweets! Cutting out dairy & much gluten makes me feel better. I don't really drink alcohol much anymore and it's good. Lots o & lots of water and yoga too help me. Also, very important to keep stress as low as possible. love from Colo
They are doing a study in Denmark compering the ocrevus vs rituximab, blind study you get one of the 2 without knowing witch one and doctors don't know either. 1/3 get rituximab and 2/3 get ocrevus. Think this is because then people can convince themselves it is most likely the get ocrevus. I was not accepted in because I didn't check all boxes for the study. So the put me on kesimpta.
Wow I've got frickn mouse protein in my system 😢smh man this sooo gross I've got progressive multiple sclerosis had absolutely no idea what I was being injected every six months
😂
So after several ocrevus infusions how can they tell if the treatment is killing any B cells and helping? Thanks Dr Boster appreciate your videos
I’ve been on Kesimpta for 6 months. Really hoping that it works for me 🎉
Glad to hear that ,For how many years
Hi Dr B - Is Kesimpta more humanized also? and is it tolerated as well as Ocrevus?
Thank Dr Boster for this community
Thank you for this information.
This is appropriate to wake up to, I just spent most of last week in hospital after a really bad reaction to Kesimpta and was told I can no longer take it. I’ve been wondering if I’ll be able to take any of the B cell depleters or if I’ll have to switch to a different type.
If it turns out you can't take them, I really recommend Gilenya
How far along were you on it?
I'm so sorry... What kind of reaction put you in the hospital if you don't mind sharing?
Thanks Dr. B! I've been on Ocrevus for a year now and it's been great for me. I got my second full infusion 10 days ago at the faster rate, but overall still took 4 hours. All of my symptoms went silent within a few months after the first infusions and I didn't have much fatigue during the "crap gap" before my last infusion (I did before the one 6 months ago). If BTKs show similar efficacy and safety, I'd switch as a long term plan to restore my full immune system and eliminate the infection risk factors. Can you post a video discussing the current state and prospects of BTK inhibitors?
Kesimpta holds my cd19 level at 0, but ocrevus only held the number at 0 for around 4 months, so it wasn’t powerful enough I’m assuming. It seems I need the monthly treatment regiment.
All my MS symptoms were much worse in the days after my 2nd half dose of Ocrevus. Should I expect this every time I get Ocrevus? It's very difficult to deal with.
No, no, you'll get used to it and your future infusions will surely be tolerated well. Best wishes from Jerusalem!
Please can you tell me if i can take Rituxan instead of Ocrevus ? ( i have primary progressive ms )
Rituxen isn’t approved for PPMS
Witch medicine would be compatible for JC virus?
Ocrevus that’s what my neurologist put me on when I was diagnosed in 2020 because I was positive for JC. O has worked wonders for me. I wish you well…!
I am ,66. Is this safe for Ocrevus ?
Very timely video! Thank you! I had been on Ocrevus for 3 years. Dose changed to every 5 months due to crap gap. Thought I would try Kesimpta, because it was a B cell depleter and seemed so much easier. Big mistake. Feel like I’ve fallen into the crap gap continuously for the past few months. I’m switching back to Ocrevus next month. I know these meds have not been studied head-to-head, but has your anecdotal experience been that patients do about the same? Thanks again!
And where are they getting these “human proteins”?
I'm on teciferda now
Is this anything like IVIG treatments
Great information Doc- these answer a lot of questions I’ve heard. #Sharingiscaring
Great to hear!
Ditto
RE: colitis - my guess is that it's not as uncommon as stated. keep in mind that no IBD patients were a part of the Kesimpta (another CD20 antibody) clinical trials. not only does ocrevus now have a warning (thankfully) but Therapeutic Advances in Neurological Disorders published guidelines for treating MS and other autoimmune disorders in 2021 specifically stating to avoid cd20 antibodies for those with IBD.
I spent the last eight weeks in pure hell because of that contraindication. definitely not worth it, more neuros need to understand the risks for their patients that have IBD. I know that wasn't the original question. I think the original question was talking about the risk without IBD, but I can't help make this point.
I just started my first brumvri on Saturday and I'm going back to get the booster on the 13th
I’m about to start on Briumvi. I’ve been on Vumerity and have a new lesion and 2 old lesions have grown significantly in the last year so - we’re changing meds. Ugh. Here’s hoping. 🤞🏻
Next month is my second dose of ocrevus, but I feel so tired these days. Is this normal? Will these symptoms disappear after taking the medication? Thank you
Thank you, Dr. Boster!!
Ty for letting explaining this! Helps alot!
Question: how about surgeries and taking these meds? I ask because I'm taking Kesimpta and I probably need a hysterectomy
He answers that question in this video at 10:28
I was on Ocrevus for 2 years and went into secondary progressive MS, switched to Kesimpta. Had to miss 3 months of it due to an initial hospitalization for an MS flare with a fever, they treated the fever as if there was an infection, as I would expect (I’ve been a nurse for 30 years), 2 more hospitalizations after that because the initial hospitalization they gave me strong antibiotics which caused CDif, then I had a rebound case of it which really messed with my MS. Been on kesimpta for about 1 1/2 years, this was my first big flare. I know Ocrevus and kesimpta are the newest meds out there . Are there any new meds, that show promise, coming soon for secondary progressive?
So sorry... Oh my! You are going through a lot! I got side effects + rate reactions from every DMT I tried before Ocrevus became available. Now I'm thinking I'm better with my original MS dx vs. all the potential side effects of new meds.
Thank you Dr Boster excellent informative answers to some great questions from the fabulous MS community. 🔥🔥💖🔥🔥
Glad it was helpful!
Hello, what do you think about TYSABRI?
He has many videos talking about his fav 5 DMTs and videos on Tsabri
If Rituxan is a cd20 depleter, then why isn’t it checked in blood work? My cd19 is low (zero), but cd20 isn’t even checked. Cd16, cd56 above normal. Others normal and IGG and IgM normal. It seems strange these other CD types are checked, but not cd20. Is there a reason for this? I don’t care if answer is “nerdy.” 😂
I was taken off Ocrevus after my first full dose, because I had diarrhea for more than 4 months following that dose.
Hey Doc! Urgent, important QUESTION: Are you going to address the unspoken but obvious change you've made??? The big metal Brain Games toy over your shoulder looks like an interesting conversation piece...😉
Excellent topic!!
Happy Monday and thank you!❤
❤❤❤good morning
I took my first Briumv B shot and had minimal side effects like chest tightness, muscle soreness. And 10 days into it, I am feeling extremely tired, fatigued, and even more muscle soreness, but I noticed it wears off the more I rest. Then the full 450 mg dose is in two weeks. 🙏🏼❤️
My medical insurance has been switching to the B-cell depletors. I asked my doctor if there was any difference in efficacy between Ocrevus and Rituxan and he didn't think there was. He seems to think Ocrevus was developed to cash in on the success of rituximab, which is much cheaper, being a generic.
Is funny you made this video, I was just thinking about this very subject, our blood tests. My MS sister or brother had my same thoughts it would seem! Thank you Dr. B 🧡🧡🧡
PPMS. Can't take ocrevus due to having breast cancer, 2018.
How long do I have to wait after Covid to start Rituximab? Nervous.
I will be receiving the Riabrii in a week or so. I have received Rutuxin but that was before the pandemic. Out of caution I did not receive any since 2020. I am 67 y/o and what my neurologist described as “ an outlier). I as diagnosed at the very beginning of 2018.
What do you think about the clinical trial that suggesting that N-acetylglucosamine restores neurological function in Multiple Sclerosis patients? Would be really interesting to cover this as well
Thank you for these very informative videos. My son (35 years old) was diagnosed 2 years ago with MS. Ocrevus has been a miracle. He has had no flare ups while on it. Previous medications did not work. At his last visit his neurologist said if his anitbodies drop lower, he will have to come off Ocrevus. She did not tell us about the infusion of IvIg antibodies so he could stay on it. We are very scared of trying a different medication, as others did not work. Should we find a new doctor in light of her not giving us all the choices you explained?
Incredibly enlightening
Thank you Doc
Be 🙏well
Excellent information!! Thank you!😊
So if O has less infusion reactions, do you think O will be used in place of R for cancer chemo treatments?
What kind of human portein??
WHAT ABOUT IF QUANTIFERON IS WEAK POSTIVE , CAN I START OCRIVUS?
I take teridlumide what does that do? I tried ocrevus had a reaction
You have a printing press!
Correction it’s.Riabni.
Question: if lemtrada is an IRT by killing b and T cells, such that only 2-3 doses are needed in most patients, why are the B cell depleters not also considered an IRT, such that they need to be taken indefinitely? What’s the difference?
I don’t know but Lemtrada is the most badass treatment In my Drs opinion(The Dr Aaron Boster 😊) Ocrevus and Lemtrada have had the best patient results. Hands down. I’m at 8 years of no treatment after doing Lemtrada No new damage of any kind. After 20 years of progressive disease course, I’m officially in remission, 5 years of no treatment and no disease progression
Hi Aaron, at a later Q and A session, could you address Ocrevus infusion times. I am on the IV drip for approx 8 hours because my body can only tolerate a full doze at a certain speed. I get dizzy, nauseous and have blinding headache despite having taken pain relief and an antihistamine before the infusion as well hydrating and eating throughout the process. Is this something I should be concerned about? Does it mean I am not tolerating through drug? I had a similar reaction with Rituximab.
Sounds like it means you do lousy on infusions in general. I'm also always telling them not to speed it up. 😏
I have MS, Trigeminal Neuralgia, Chiari Malformation (Surgery 2012) and Addisons Disease. i had plasmapheresis to start. Then multiple hospital stays for Soli-Medrol within the last year, i was on Tysabri for 8 months & continued to develop lesions. I just had round 2 of Ocrevus & im Praying it works..I went from being at the gym to in a wheelchair within a year. 💜
I hope and pray that Ocrevus works very well for you! love from Colo
Hugs
I’m a zipperhead as well 2020
❤
(From Montreal) Hello Aaron. I'm on Ocrevus infusion (every 6 months). I would like to know why I must wait 4 and a half month after the infusion, and 1 before the next one, to receive a vaccine. And thanks so much for your videos and such useful information :)
I had this question as well and what I was told pertains to the the actual B-cells. Most vaccines function from a B cell response, meaning that the dead virus that's injected via vaccine needs B cells to generate antibodies against that virus. So when you are taking a B cell killing medication, you don't have the B cells in your system to create the antibodies, meaning the virus has a lower efficacy. I'm on Ocrevus as well and this was the simple answer and understanding I have of the situation. Hope this helps!
I recall he did a video addressing that specific question previously. He should have that video on his channel.
@@Fishbone8891 Thanks :)
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My neurologist has asked me to research and consider the bi annual Ocrevus infusion, after a recent MRI shows two new lesions on my spine since the last MRI three years ago. Looking on Google, the good, the bad and the ugly has become very confusing. For the most part it seems to have some very nasty side effects - which is a bit disconcerting. I’m currently taking a daily Gilenya capsule which has been very effective in stopping the yearly relapses I was having while on daily Copaxone injections (and a far more pleasant way to fight MS). With Gilenya I’ve only had one relapse in several years and was surprised to hear of the new lesions. Could you please share your valuable experience with what to expect and the scenarios you have witnessed. Thank you for all you informative videos, it’s wonderful to hear your no nonsense and learned opinions. ❤
P.S. I live in Australia so may or may not have access to all that is available in your country.
If you have new lesions then the drug is not really working.
@@ecarlson4987no it’s not. I’ve been on 5 DMTs and failed at them all but Lemtrada has me at over 8 years. With no treatment. Since 3 days at the end of year 1
Hi from Israel as usual interesting data I hope to have more information about taking vaccinces during taking treatment to theMS especially on Tysabri and Ocrevus thanks what is the best time to get them