Dr. Paul Mason - 'Sunlight and health - from Vitamin D to Fish oil'
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- เผยแพร่เมื่อ 19 ก.พ. 2019
- Dr Paul Mason obtained his medical degree with honours from the University of Sydney, and also holds degrees in Physiotherapy and Occupational Health. He is a Specialist Sports Medicine and Exercise Physician.
Dr Mason developed an interest in low carbohydrate diets in 2011. Since then he has spent hundreds of hours reading and analysing the scientific literature.
For the last three years, Dr. Mason has been applying this knowledge in treating metabolic and arthritis patients who have achieved dramatic and sustained weight loss and reductions in joint pain. - วิทยาศาสตร์และเทคโนโลยี
I don't care what the topic is. If Paul Mason is speaking, im listening.
When a doctor is 40 years old and looks like he's under 30, I tend to believe that he knows what he's talking about when it comes to nutrition...
Spot on
youfe very naive if thats all it takes
I've found judging anything by appearances doesn't cut it, lots of slender healthy looking people get diabetes etc, and the more dolled up quite often the more messed up. But as in everything not always the case. But I have seen and experienced much to support this drs hypotheses.
How about K2
I've followed him for some time now and was always amazed that such a young guy could be so grounded, knowledgeable, and supremely confident. Then I found out he was quite a bit older than I thought. I rather suspect that his physical appearance is likely due to epigenetics, though there are exceptions, but time and again I have observed that people who put effort into health and wellness age more gracefully.
As for TOFI's (thin outside, fat inside/NAFLD/diabetics, etc), that's absolutely true, but they very often have outward manifestations that are telling, ie, nail, skin, hair, eye conditions, even facial formations. There may even be manifestations on the bottom of feet as there are meridians that run through the body that carry signals or "refer". As for facial formations dictated by health and posture, Drs. Mike Mew and his father (dentists) give amazing proof that epigenetics is the determinant in most cases. I could go on.... stop.
Dr. Mason is aging beautifully and that is noteworthy.
I'm fair skinned 72 yo Scandinavian. Since removing vegetable oils, I no longer sunburn. I've been on Hawaii past 2 months, and even spending 2-3 hours in sun doesn't result in a burn. Also, age spots on my hands are disappearing. I stopped supplementing with omega 3s several years ago.
What oils do you use instead ? Thanks.
@@liverpix coconut oil ✅
NO seed oils 👈🏿. NONE.
@@snowyowl6892 I've discovered the same thing. It's interesting I do not burn anymore at all. I quit all seed oils and sugars.
I quit eating seed oils and sugar, - so now I just eat things like cake and potato chips
the same is happening to me.....sunbathing used to sting my skin. Now it doesnt and being fair skinned I dont burn like i used to. Especially sing eating a lot of saturated fat.
Following Paul Masson for many years now. Such a smart man
Loved this! I'm a natural redhead and have always been warned to "stay out of the sun!" by doctors, friends and family, but I just ignore them all. I try to never burn, but I get outside in the sun every day it doesn't rain just because it feels so delicious on my skin and I've never believed that being a pasty-face looked or actually was healthy!
I am a 61 yr old redhead,roofing contractor, in the sun a lot hundreds of burns on the back, all the freckles grew together for a permanent tan, the sun is great, smearing poison on the skin is a fraud. the answer always seems to be the same, natural is best. i do wear a hat for protection ,and no sunglasses or limited.
Hi...we are told to listen to our senses (our instincts), and I have always had this feeling of being happy/relaxing/soothing/comfort from the Sun. If I may say to other's - be careful using sunscreen, as our skin absorbs these chemicals. Back to the Sun...Beautiful. Excluding some insects/sea life in the deeps...Sun is important for the growing and the Living.
I agree with you Laurie!! Fellow ginger here!! We have been tracking our vitamin D levels and have not had any Covid myself and like you said I feel much better soaking the sun! We have our wine time in the sunny evening. Don’t you think it’s funny that the Pale, sun avoiding people always get the skin cancer? I’d more tend to believe sunscreen and seed oil consumption causes melanoma before sun does!
Sun is our one and only good. Bask in its benevolence and never dare stare back at it
30 minutes to an hour without protection before 11:00 am and evening. He mentioned the shadow rule. Best time to sun bath is morning and evening.
There's a huge problem with the first study discussed at 14:22. The experimental group was given only 800 IU's of Vitamin D, a significantly lower dose than is recommended by numerous organizations which concede that even as much as 2000 IU's are generally not enough in adults.
That is a study that should be taken with a grain of salt.
100%
@@karenf9137 Yes, My anecdotal experience with Vitamin D (10,000IU daily) over the last 2 years has resulted in a huge reduction in respiratory infections in my case (virtually zero) while I still have all of the risk factors.
So I think that especially for us in the northern latitudes supplementing with vit D3 is still useful for immune system performance.
The information provided however seems extremely valuable. I was aware that there seemed to be advantages in sun exposure and light therapy for other issues including as blood flow and pressure. I am delighted to see that his research suggests that I might still receive some health benefits from sun exposure even in winter.
Couldnt agree more. Just commented this lol.
The level used to be 20. The reason that children had rickets was not lack of vitamin d... It was because we worked them in factories and there was no mandatory education. When they were able to play on the sunshine again they quit needing supplementation of vitamin d which is actually a hormone. There's also numerous types of vitamin d, but only one is tested for. This guy is a doctor to Olympians. He didn't graduate at the bottom of his class.
the question i have is, does vit. D supplementation promote nitric oxide release at all? Or only exposure to uv-a does
Love this guy
Rachel Britton me too!
@@archereaster611 Yeah I bet he's a real hit with most of the ladies!
The muscles are pretty obvious. I am hungry now
OMG!!!!!! You have just given me the answer to what I have noticed has changed in my increased SUN EXPOSURE TOLERANCE..... I thought it was just due to ONLY being low carb high fat KETO but now I know it is also to do with my fish oil supplements - you have no idea how amazing this info is for me.... for years I have burnt in just 10 mins even at 7am of a morning living in coastal Brisbane recently I went to Toowoomba and walked around in the blazing sun for 6 hours in shorts but with a long sleeve cardigan and a hat and only ended up with a bit of sunburn at the tops of my calf muscles on the back of my legs. I am amazed!!!!!! You have provided me with such strong info to explain my experience. I used to suffer with lupus (1989) too but I over came that 10 yrs later too! This is a GREAT presentation and yes, I do understand association does not prove causation. THANK YOU xxx
Also look into Omega-6 / Omega-3 balance. Reducing your intake of Omega-6 (vegetable oils, fats from seeds and nuts) etc, and replacing these fats with animals fats and thereby improving your 6/3 ratio should have a similar effect on sun tolerance.
Yes Omega3 increases VitD absorption. So I feel this doctor has missed the connection between the 2. Fish oil has D and Omega 3
what sort of fish supplement do you take?
Don't eat margarine, or vegetable oils, eat butter, extra virgin olive oil, avocado oil, good fats. Don't use sunscreen. Coconut nut oil good on skin.
The vitamin D study you reference was only giving 800 iu per day, which is very low. I'd like to see a study where they give 5,000 iu per day.
yup, me too
Same
Walking to and from work on sunny days would make a lot of sense.
Walk outside during your lunch break :) Or sit and eat in the grass, bare skin touching the earth.
Thanks, now I know what happened to me. I have an undiagnosed problem where just randomly my blood pressure would spike up to scary levels for half an hour. After two years I realized the problem mostly only happens during the winter. Got a UV lamp and was magically cured. No doctor or nurse could tell me what the skin does with the sunlight that could prevent erratic blood pressure. Now I know.
Hi, what kind of UV lamp did you buy? I want to buy one too, but I heard they can make cancer as they damage the DNA.
I had the same problem... My cure was a carnivorous diet. I went off two blood pressure medications and am down to 1/4 of the remaining one. I have been ambulanced off of work and twice from my home from extremely high blood pressure even on those three different medications. Now it's typically 110 over 65.
At 14:25, he talks about a Vit D study where participants are given either 800 IUs per day or placebo. It is well documented that 800 IUs per day cannot significantly raise one's Vitamin D levels very well. To raise 25(OH)D levels significantly, one needs to take a minimum of 4000 IUs (100 mcg) of D3 per day. Of course that study that he cited didn't see any difference. The designers of the study didn't use enough! I'm with Sanguine here, Dr. Mason is drawing conclusions he can't back up.
4000IU/day is noted the upper safe limit. That 800IU/day cannot raise VD levels I would like to see the source for this. 'Significant' rise doesn't help your argument as it simply implies that a small rise has a noticeable beneficial effect, and thus large dosing isn't neccessary.
My immediate reaction as well, we've seen the same problem with trials of epa/dha supplementation where they low ball the dosage to ineffectiveness. 5mL of water a day won't prevent dehydration, that doesn't mean water is ineffective for that purpose.
@@akanecortich8197
4000IU/day is not the safe upper limit. No deleterious effects have been found up to 30000IU/day.
Akane Cortich , I don’t think 4,000IU is the upper limit. I fill prescriptions for 50,000IU capsules that are to be taken 1 per week, that would equate to nearly 7,150IU daily, also wouldn’t taking 50,000IU be ill advised if 4,000 is the safe limit.
P Retzel - you've remained quiet - why haven't you defended your position
Need to consider dose response to vitamin D supplementation. 800 IU is very low dose.
And if i'm correct this Vitamin D in supplement form gets poorly absorbed, unlike the vitamin D from the diet, especially in animal food.
Excellent lecture, a lot of work went into it, thanks Dr Paul.
Never had skin issues when I work under the sun all the time. Now that I’m avoiding the sun I’m getting skin issues such as keratosis and acne 😔
I absolutely love the smile plus the challenge of the medical "established standards" of health. This is the Sherlock Holmes of medicine: nothing is true unless researched, thought about it and then confirmed correct. Love this doctor!! He clearly loves human kind and wants health for all. Can't fake this. Interesting he is not from the USA. Food for thought.
Totally agree with you
Excellent presentation Dr. Mason. Thanks a lot
My skin is normally pretty pale in winter months but after cutting out processed foods seed oils and going carnivore I no longer burn with long term sun exposure anymore.. I shave my head and it normally peels from sunburn a few times a year. Last summer it didn't peel once even with a Florida vacation without sunblock or a hat being worn. That was 6 straight days in the sun at theme parks. Not only did I not burn I had a rather dark tan that some of that color still remains now in February. I heard an explanation in a few places that this could be from a better omega-3 to omega-6 fat ratio? I do eat cod liver salmon and sardines off and on to boost my Omega-3 along with daily cod liver oil iodine and lots of sea salt as my only supplements. This information is huge for me since my mom passed away a couple years ago from melanoma that started in her eye and spread everywhere after her eye was removed
Excellent lecture. Well done Paul.
I have brown skin and my diet includes a bunch of fatty fish, so I can tolerate more UVB without getting sunburned. Yay for me.
Me too homes :)
Interesting how opinions and interpretation is dynamic and continually evolving! On a very recent pod cast with Paul Mason & Shawn Baker, Paul states that most liquid fats such as fish oil and olive oil are very oxidised and that the best way to ingest Omega 3 oils are through grass fed meats and the actual salmon or mackerel itself, he doesn't now recommend the oil supplements...
im on a path of trying to find out if fish oils are a waste of money... everyone is all over the map concerning the efficacy.
@@alistairbalistair9596 please let us know of the results of your research
@@alistairbalistair9596 Try and find out what Bart Kay says about it.
I know.
I saw that earlier video too.
So, should we take fish oil or not.
I was going to give it up, based on earlier video. Just try to eat wild caught fish, mainly salmon, which I love.
Humm🤔
@@alistairbalistair9596
No doubt
did not think id watch this entire thing but here I am at the end. great content.
great talk, thank you.
That was an amazingly information-packed presentation!
I live in Phoenix and i never sunburn no matter how much I get. I’m convinced this is due to my strong nutritional profile
Once your skin is tanned and conditioned you can stay in the Sun all day long without burning.
You probably don't eat highly reactive seed oils to make your skin cell membranes out of.
Me too.. actually I live in Peoria..
I burn in phoenix easily cause in stuck inside an office all day
What’s your nutritional profile ?
What can we do in Ireland? We have blue white skin and even when we try to tan on holiday abroad our skin goes red and can blister easily.
Keep up the great work
Easy listening,well presented info.Thanks!
When I take Vit-D in the fall and winter, I don't get colds and flus. Before I took Vit-D, I got horribly sick two to three times every fall and winter.
Another brilliant talk , thank you.👍💖🇬🇧
This is so interesting. I learned so much.
I've always felt that the sun was healing me when I was in it!
Thank you for this. Very well presented and clear.
Really good information. Thanks
Excellent presentation
also together, D3, Mg and K2mk7 is associated with improved bone health, reduced vascular calcification and also maintaining elastin integrity of the vascular system, thus protecting against future CVD.
But...does this apply to everyone? I read African Americans do not need vitamin d3 for bone health....
Akane Cortich Just make sure you fully research D3. Read my comments above. Google: D3 - Cholecalciferol Rat POISON.
What vitamins do you recommend taking daily? Or is a multivitamin enough?
''smokers who had the highest level of sun exposure had an equivalent level of mortality as non smokers who have the lowest'' wow......!!! i am smoker but my D level 51, thank you.
Great talk!
Thank you Dr. Paul Mason for this enlightening presentation. It clears up a lot of confusion concerning sun exposure.
Enlightening indeed! He has shined a light on the data, illuminating the salient points. He is a bright doctor with a sunny disposition whose intellect shines with brilliance. I was dazzled by your glowing comment, and although I could never outshine it, I wish to kindle the warm glow engendered by your light-hearted praise until it bedazzles the whole world.
Am grateful for all the good info you share Dr. Paul Mason. Thank you very much.
On skin and sun rays, though, am skeptical. The reason is simple. I have experienced sea changes in one's tolerance to sun light with regular intake of a local herb fruit for a couple of weeks. Like you can actually go out in the sun in the middle of June in my home town of Multan in the south of Punjab province in Pakistan, and actually contemplate whether or not the heat was greater today compared to earlier. There is no reddening of the skin and no troubling discomfort from the excessive heat of the sun which is VERY strong in my hometown where some time it is as high as 51 Celcius!
So we were very concerned when we moved back to Multan from Lahore in 1999. It is part of the local lore that this herb fixes the issues with heat tolerance. So we not only took it ourselves but also gave it to my daughter, 6 and son only 2 then. We lived in a mud house in a village for seven years and the kids would play with other village children out in the sun a lot of the time during the day!
So, I think there is nothing in the UV rays per se. Rather it appears to be some needed food bestowed immunity you folks seem to be lacking. The herb in question is known as Aksan, which is the name of the plant whose roots are called Ashwaganda and the part we took was its ripe fruit called "Paneer Doda". It is the fruit that is used to curdle the milk for vegetarian cheeses!
Best regards.
PS: only a water infusion of the fruit is taken. The fruits are thrown away after being soaked overnight. 20 pieces to a cup of water for each adult is the regular dose for two to three weeks that makes you immune to the heat throughout the summer and my hometown is known for its grilling hot sunshine!
Wow i am from karachi and always played outside as a kid. Multan is definitely hot!
That's very interesting, thanks for sharing!
Nonsense, you're confusing the difference in skin colour with nutrition. Your skin is adapted to warm climates (a Sub-Saharan African would be even more), while the doc's skin is adapted to cold climates - your skin wouldn't absorb enough in a cold climate, while his is absorbing too much in Australia. Being raised in this or that climate helps though, as children are incredibly resiliant and growing up in an extremely warm climate, the doc's much better adapted to live there than someone like me, who's grown up in a much colder climate, even though our complexion is about the same - and it's for the same reason your children were able to take it, the fruit water most likely just helps to keep you people hydrated, as plain water can be hard for our bodies to use in extremely warm climates.
Great lecture 👍
Good stuff Doc!
Great video, great research, great presentation. Thank you. I'm going to get some sun now.
They were only getting 800I/U of vitamin d in the study you displayed. I take 10,000I/U per day. RCT's show that only intakes above 30,000I/U p/day begin to produce 'toxic levels'.
Wrong! Up to 50,000IU a day is safe.
Very informative.
He made love me love margarine in the first part of his lecture, then hate it in closing.
This dr is a genius! Aaa+
Nah. There are more accurate and deeper presentaions. But at least he looked and shared his findings even if he has missed a couple of things.
@@Noor-jw2tn well, who does it better?
Thank you
Omega3 increases absorption of VitD.
I've read/watched many studies that said most fish oil is rancid and could have a negative reaction to your system after prolonged use. Any opinions?
11:33: Any discussion about health should not mention margarine unless it is to highlight the fact that it is an inherently *unhealthy* option... even if it is fortified with Vitamin D.
He did. Listen to what he said about it
Don't doctors prescribe the D2 form of D? What form was used in the test subjects? D2 or D3? Was K added to the D as well? So many questions.....
Dr. Mason,
You mentioned that people with skin cancer lived longer than people that have never had skin cancer.
Is it possible that this is due to the fact that people who have had any form of cancer will get regular and frequent medical check-ups for years after their diagnosis/cure, whereas many non-visibly sick people just don’t bother with precautionary check-ups? The result being that the non-skin cancer people end up dying from all of the usual conditions, and the post-cancer patients get these hidden conditions noticed and addressed before they become a killer issue.
I wondered if the difference in the Swedish studies (people who take sunbathing holidays have better mortality outcomes than those who don't) reflected their incomes. Poorer Swedes would miss out on holidays or holiday locally, or at less expensive, less sunny times of the year, whereas the well-off would be able to afford to go to the sun at peak times.
That's just one of many confounding variables in these studies, you have to take them with a grain of salt.
What about high mortality among people that watch youtube all day
lol....that study needs to be redone..it all depends on what you are watching ;)
Very helpful
For those of us who live in cold, icy climates where there is no sun much of the year, are tanning beds a relatively healthy alternative? Thanks!
Thank you dr Paul Mason for excellent presentation.
The ginger is strong with this one.
(From one to another!)
Studies giving 800IU per day should not be expected to show any effects, the dost is far too low. On a sunny day, we can easily make 25,000IU. And while nitric oxide is a benefit of sun exposure, there is also systemic production of melatonin, which may be a more important effect for health and longevity.
As long as money is the driving force in science ,there would be no be no great benefit for humanity!
The darker the skin, the more sun exposure we need to boost d3 levels. Uva and uvb work with each other both are essential.
That's why they are present at the same time. Of course they are essential. 😁
but what happens if you have to stay in hawaii sun for hours?
It would be interesting to do this study in Canada; with its long, dark, very cold winters, requiring us to bundle up head to toe, and our short, not always warm enough to go outside with minimal clothes summer.
Tinned sardines in olive oil, might be our best source of Omega-3 fatty acids, especially since fresh fish is expensive here.
Avoidance of Omega-6 fatty acids is vital; it is hidden in so many foods…. Inflammatory.
im surprised you never talked about infrared light
Did they control for actual rise in serum concentration when they conducted their studies? What if 800I.U od vit D did just not increade the blodd levels substantially?
Great presentation by a total cutie!
I’m not gay but I certainly would.
Not really. Your taste in men is poor then… if he’s cute then I’m a god
Top of the game Paul
In the study where 800 IU of D3 were given (14:36) this dose is far too low to prove anything. Its like saying we gave patients a quarter of an aspirin a day but concluded it does not improve the symptoms of a headache. People should be taking 5000IU of D3 a day at least IMHO
Thank you Dr. Paul, generally what about the darker skin types, (Black, brown..etc)?
Not only do people with darker skin tolerate more sunshine better ......but they need more sunshine to create the same amount of vitamin D as people with lighter skin.
Matter of fact there's a theory that the reason many black people in North America have high blood pressure is in large part due to the fact that they don't get enough sunlight to create the required amount of vitamin D.
Just get more sunlight. Darker skin means you'll absorb less. Also means you won't get burned or end up with skin cancer though. I'm sure you probably know all this by now but I decided to answer anyways lol.
study with Amount of Supplemental of D 800 ? Considered by some experts to be too Low to raise vitamin D levels to adequate levels. The other two studies cited did not list level of D given.
Also I heard from Dr. Mercola that you shouldn't wash immediately after sun exposure because it washes away the oil needed to produce the vit D
Would direct sunlight be contraindicated in those with rosacea...and specifically, cause the progression of rhynophima?
So, is it good to take fish oil or not? In one of your other videos you said, most fish oils tested, were rancid/oxidized.🤔
Humm?
Thanks Doc
ClassicJukeboxBand
2 years ago
When a doctor is 40 years old and looks like he's under 30, I tend to believe that he knows what he's talking about when it comes to nutrition...
I like to go tanning at a UVB bed. Looks like I'll start trying the higher UVA beds. I also like to take off my glasses and look in the direction of the sun, having it shine in my eyes but not directly.
Huberman talks about this stuff in many of his utubes. .. i inferred UV A good UV B bad probably to big a problem to infer either... natural (liver made) Vit D probably more important than any pill D2 D3 label wrong anywaZ
I drive a truck. Sunlight through glass does not make Vit D. usually have drivers side window open thoigh so that should give plenty.
Have seen pic of truck drivers facing the wi dos with .ore Sun damage than side that is not.
Doctor Mason i love your work but would it not be true that those who went on holiday would be wealthier and therefore have access to better food and education than those who could not afford a vacation?
There are always quality differences in types of vitamins eg. synthetic/fractionated vs. natural, organic food- extracted complete vitamin complexes with huge differences in effects. Do the studies specify the types of vitamins used
Is sitting in the shade or being out on cloudy/rainy days factors in amounts of available vitamin D vs. being out in full sunshine?
Isn’t there a need to supplement bioavailable magnesium with VitD for the body to properly metabolize D3?
And K2 to help with calcium absorption?
Flax seed have the highest ratio of omega 3, as do chia seeds, and Salmon, walnuts,.. Flax and chia seeds should be soaked before consumption to reduce the phytic acid and aid digestion.
plant sources are short chain not long chain which are what is actually required by the body.
All seeds and nuts should be soaked to reduce anti nutrients...
May I use your slides for my presentation .
Thanks in anticipation
the diabetes drug metformin is being studied for it's positive effects of longevity. The current speculation is that it reduces overall cellular inflammation
Exercise works better than Metformin
That drug aged me. It robs you of vitamin b12. No one tells you that. I was on death’s door and had to figure it out myself thanks to the internet NOT USELESS DOCTORS.
I wonder how long the advantages of exposing yourself to UVA last for and how often we need to be exposed to it?
If not in a climate like Australia then has to be by diet or supplementation.
yeah more details would be useful?
Dr Paul Mason: 'vit D supplementation doesn't help longevity, sun&UV good for health/longevity, nitric oxide > vit D(for longevity)'. Comments 'Wow thanks Dr Mason, I have been taking 1000 000 IU per day, feeling great.'
I used to burn and peel easily but now I eat grassfed beef I'm not peeling, just getting darker. I've read gf beef is high in zinc.
Great lecture as always from Paul Mason. Unfortunately no info on benefits or lack of benefits from sunscreen, it's a really controversial topic.
Check out Dr Jack Kruse (neurosurgeon) re the truth about our need for sun.
NO SUNSCREENS and
NO SUNGLASSES
- he will explain …
Since I eat mostly fatty meat I don't burn my skin and I love being outside so much now.
We found Vit D lowered the BP quite significantly (post Covid), so those with Hypotension should measure Vit D intake against their BP propensity.
How many minutes should we be exposed to the sun in a day?
Correct for ice on the roads?
Your an Aussie, so easy for you to say. What do you say to us Canadians who don't see the sun sometimes for weeks at a time? I was raised in the Caribbean, with all that sunshine they are no healthier? Notice the question mark.
I think the problem of sickness is lack of boron in the soil in the Carribean.
Im Aussie I take 20,000 IU daily.
there are loads of people in the low carb movement saying fish oils are ineffective.
Correct me if I'm wrong...Nitric oxide is produced when we breathe through our nose.
Does windscreen glass attenuate UV rays? I live in the tropics and have never worn sunglasses but my optometrist says my eyes were protected behind the glass.
Yes. UVB doesn't pass thru glass.
May i know what is the Final word, do we need sunshine in the mornings? Or mid morning?
I'm going to sunbathe. thanks doc
800 IU D is a very low amount.
Study didn’t specify if D2 or D3 used.
Nor did it say if Vitamin D3 cofactors were used and dosed correctly.
Vitamin D does not work alone.
Need
Vitamin K2 (not K1)
Magnesium (not oxide form)
I wish they had shown what
5000-10,000 IU D3 benefits were.
How does one find a physician who is willing to discuss, consider, or even look into these studies that contradict their institutional medical dogma?
So is sunlight/UVA the only way to get our skin to produce nitric oxide?
There was no mention of taking dietary sources of nitric oxide such beets, pomegranate seeds, etc. Is it fair to assume that this is as beneficial as a source?
I think due to the extremely high oxalate content of beets, they should be avoided as a means of increasing nitric oxide, or anything else, for that matter.