Glutathione, Methylation & Nutrition w/ Dr. Russell Jaffe
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- เผยแพร่เมื่อ 21 ก.ค. 2024
- Science says eating just one meal per day can improve your health.
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Episode #56: Russell Jaffe, MD PhD - Glutathione, Metallothionein and Vitamin C: key detox molecules
Dr. Jaffe shares his top tips to increase glutathione, metallothionein and methylation.
➢ Link to full show notes and Dr. Jaffe's contact info: highintensityhealth.com/russel...
➢ Listen to the Audio in iTunes: highintensityhealth.com/itunes
----------------------------------------Lets Connect-------------------------------------
➢ Facebook / mikemutzelms
➢ Instagram / metabolic_mike
-------------------------------------Key Takeaways---------------------------------
06:27 The Power of Epigenetics: We have shifted from a focus on metabolism and biochemical individuality, to epigenetics - your lifestyle, habits, and choices regarding what you eat, drink, think and do determines 92% of your lifetime health that is not genetic. A small fraction of our health is determined by our DNA and our genes.
08:30 Effects of Toxins: It is your internal adaptations that determine the effect that toxins will have on you. For example: toxic metals can be a serious problem, but if you have enough healthy metallothionein to take up and detoxify those metals, they do not stay in your body. If you have switched from this elective/protective mode into survival mode, then your body cannot devote the energy to detoxification in order to deal with the immediate crisis.
10:41: How Does Metallothionein Work? Metallothionein is a protein made of two amino acids: glycine and the sulfur-containing cysteine. Metallothionein is a magnesium/zinc rich protein that gives up its magnesium or zinc and irreversibly binds to any of the toxic metals, like mercury or lead. They are then excreted from the body through sweat, stool, or urine. Metallothionein is everywhere in our bodies and is measureable. When we shift to survival mode, toxic metals begin to accumulate. The same happens with persisting pollutants, volatile chemicals and the risk of exposure to radioisotopes or other environmental pollutants.
12:44 How to Upregulate Metallothionein: A diet rich in sulfur foods, you can build metallothionein, if you stay alkaline and you have a balanced nutrient intake, appropriate for your lifestyle. Metallothionein is very important to our long term health and survival. Nutrition begins in the kitchen, in the cooking pot. It begins with whole foods that you consume in as whole a form as possible. GGOBE is an acronym he uses for top sulfur-rich foods. It stands for garlic, ginger, onions, brassica sprouts and eggs.
16:55 Whey Protein: Whey protein is high in cysteine.
19:22 Metallothionein and Glutathione: The purpose of both of these is to protect us. Glutathione is synthesized inside of cells. Oral glutathione may help the gut and the mucosal barrier, but it does not go to your body’s cells. Glutathione is an important intermediary in keeping oxidative stress low. If we give the precursor amino acids for glutathione production in cells, GGOBE foods or supplements that contain cysteine, methionine and we have a healthy alkaline cell with mitochondria are healthy, we can make glutathione.
21:58 Mitochondria and Cell Health:The cell protects the mitochondria and the mitochondria give the cell ATP. The mitochondria also detoxify things like pesticides, persisting pollutants and hormone disruptors. These must be detoxified inside the mitochondria. If the mitochondria are overwhelmed, then the energetics of the cell slows and uses up Coenzyme Q10, which is the electron shuttle, impairing things further. About 66% of our detoxification happens in the liver. Maybe 15% of detox happens in the kidneys. A small percentage takes place in the spleen. Some also happens in our skin. Every muscle, every cell of the body does some detoxification and utilizes mitochondria to do that.
24:50 Ascorbate and Raising Glutathione: Unlike vitamins, ascorbate does not activate catalysts. It is used directly. It is a sub straight. It is used up in the course of detoxifying, energizing and protecting the other antioxidants in the body. Ascorbate is the correct name. It is the mother protective molecule for all other protective molecules in the body. The best way to raise glutathione in the cell is to give ascorbate. The amount of glutathione that you generate is proportional to having enough ascorbate.
27:42 C-Cleanse: Quickly saturate the body with mineral ascorbate, so you have calcium, magnesium, potassium and zinc minerals along with the ascorbate. Toxins and fluid are flushed out of the body. When you have taken in the amount of ascorbate you need to protect from oxidative stress, you are also maximizing the glutathione inside the cells.
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Thumbs up for telling food sources at start of video rather than making people wait.
What hamble man 🌹👍🏻
@@abdulelahkhunji6871 Humble 😉
I loved that to, very respectful so everyone gets that vopied and c a n then really get into the discussion happening. I learned about metalle thiamin. I fwdwd this video to a friend who has been bed ridden since her 20s when she had amalgams placed.
I shared this immediately! Here's praying.
@@imsaltylit3101 ❤
You do an extraodinarily good job at interviewing your subjects. Never floundering, right on point with them, asking good questions, engaging, quick, focused. I've only seen a about three so far, but I wish some professional journalists would watch you and learn how it SHOULD be done! Bravo! So glad I found your informative channel. You're a breath of fresh air from the stammering idiots who attempt to interview really knowledgeable people and completely blow the opportunity by being disinterested, unprepared, and disingenuous, which always leaves me feeling like, "well, I'll never get those 45 minutes back, thaaanks." Really good job in my humble opinion. More, please.
Why thank you, Rob! So grateful for your feedback.
Hope you've enjoyed some recent shows,
Mike
I agree! I was feeling the same gratitude...carry on. You are wonderful! You bring out the best in each person and it is inspiring. Blessings and aloha, Claire
Thank you, Claire!
Much appreciated,
Mike
High Intensity Health, I agree with the comments on your interview skills. You are lucid and humble, allowing Dr. Jaffe to gracefully go on his tangents (which are incredibly informative), and redirect him with ease. Thank you for your contribution here. It's the first video I have seen of yours.
Why thanks, Bradley!
Keep working on it everyday.
Cheers,
Mike
It is always a good idea to follow dr jaffe on his tangents!!!
Well said, he's phenomenal at what he does
this guy is brilliant, we need more of him
Agree, Linda!
Have you seen this episode with Dr. Jaffe? th-cam.com/video/7yEaelfx7f4/w-d-xo.html
Linda Puertes Deals
Actually, I'm sorry to say, he isn't...b/c you COMPLETELY DESTROY all the health benefits of garlic when you roast it...
This was incredible. I was surprised to find this showing up since it is 8 years old. This man knocked my socks off with the level of information in such a short and concise manner. I really appreciate Dr. Jaffe and you Mike you getting him on your podcast.
When I was diagnose with stage four bone marrow cancer, I soon after had an intuition to use plenty ginger, both fresh, and ginger powder in my morning smoothie.
I also ferment garlic in honey. Anyway, I am at 75 years young, and nine years in remission, and in excellent health. I have no need for any pharmaceutical junk medicine. If I did I
would find a natural way to cure myself.
I'm dealing with histamine intolerance, severe brain and cognition problems and I had intution to look up histamine intolerance and methylation and it led me to metalothionein and that led me to this video. I do believe in Jesus Christ and I do pray alot and I just woke up today about an hour ago with this though (which i believe came from God) and led me hear, and I immediatly looked roasted garlic recipe. I have been craving onions and garlics anyways! never knew you could roast a whole bulb! I hope to find healing and thank God my father through Jesus Christ for this all because if not for my faith, i would have ended my life over 20+ times due to such bad spiritual and physical problems the past 36 years i have lived on this earthl
use high dose of msm+vitamin c, you will live up to 100 years
MasterofPlay7 ☺️
MasterofPlay7 how do you know?
Wow such a generous man this Doctor is that he came here to share his knowledge with us! I'm really grateful, thank you 🙏
Finally, a real doctor on TH-cam.
whereistherealslimshady? Check out Dr. Mark Sircus, too!
What about Dr Ken Berry and Shaun Baker. I thought they were real doctors?
I have been studying translational medical science for many years. Dr. Jaffe has the best combination of basic deep understanding of chemistry, through biochemistry, through molecular biology and how to apply it to the practicalities of living of any qualified clinician-scientist tfhat I have found so far on the web. My hat is off to you, sir. I can't get enough of your wisdom.
I'm dealing with histamine intolerance, severe brain and cognition problems and I had intution to look up histamine intolerance and methylation and it led me to metalothionein and that led me to this video. I do believe in Jesus Christ and I do pray alot and I just woke up today about an hour ago with this though (which i believe came from God) and led me hear, and I immediatly looked roasted garlic recipe. I have been craving onions and garlics anyways! never knew you could roast a whole bulb! I hope to find healing and thank God my father through Jesus Christ for this all because if not for my faith, i would have ended my life over 20+ times due to such bad spiritual and physical problems the past 36 years i have lived on this earth.
How is your health now?
I can relate with the physical and spiritual battle.
I am reminding myself that I need to trust The Lord with my life and that no matter whether He leads me to healing here on earth or until I’m in heaven that He is still good, merciful and worthy to be praised.
Eat nettle
This is amazing. I am overwhelmed with emotion at all this valuable information. Thank you
Valuable information! Dr Jaffe is brilliant, and the interview, as always, was enjoyable. Thank you for what you do, Mike 🙌
this is freeking amazing what a video man should have much more views..
simpy awesome interview, one of the best I've ever seen..well done to both of you
Mike thank you so much for doing what you do. This video was a game changer for me. I deeply appreciate your seeking out and sharing vital and intelligent information for the betterment of our health and well being. Keep rocking it!!!!!
This MD is amazing. Thank you so much for this talk with such an informed individual. I subscribed.
This sounds very complicated, I went through all the various diets, strict vegan for 13 years. Macrobiotic, plant based, omnivore, spent tens of thousands of dollars on various supplements, whey, spirulina, multivitamins, juicing, Made my own sauerkraut did the raw Hippocrates thing for years. Stayed away from red meat for 30 years. Ate garlic and onions til I reeked. Nothing but slow weight gain, a few pounds a year, grey hair started at 23 years old, my teeth started to decay, cavities, and grinding my teeth at night. constipation even though pumping the raw vegetable's, fruit, kraut ect. I am 64 now and went to nothing but animal foods, mainly grass fed meats and organs, bone broth, some raw milk cheeses wild caught fish.. Lost 25 pounds of body fat, gained unbelievable strength, I feel like great mentally, energy is way up. Not concerned about bowel movements. Gas and bloating gone. I feel my colon is starting to heal after all the fiber The only supplements I take now D3, Selenium, Iodine, MSM. cod liver oil.
That's fantastic! Similar experience here! Switched recently to mostly animal foods, I feel better than ever before! Lots of energy, brain fog gone, no more bloat belly. Meat heals! 🙂
What is your blood type? You must be O+
@MsPerfectly Imperfekt Methylsulfonylmethane
@@kwasikumah3491 Please, could you direct me to any resources regarding blood type and health?
this is the best talk i ve seen in awhile .excellent interviewer .thank you for the info.
A Great Interview!!! Everyone should take note. Thanks Doctor Jaffe.
Where was this video! As I regret no having seen it before. In just eleven minutes of video and I already feel like I need to know more.
thank you for having patient in going deep.. Its so awesome.. i want to work in this area again @58 yrs old.. Please keep it coming❤️
Dr Russel is a genius
thank you so so much for this amazing information and some history behind the nutrients, it was refreshing to hear a medical person giving such wonderful advice. very grateful to you all
love and light
karen
Thank you Mike you do a great job talking with Dr. Jaffe! I agree with the prior comment, but this is TMI, where do you start? thanks again, this is a wealth of info. & i love you!
EXCELLENT tutorial. Thank you both very much!
So i did not understand something
Is Ascorbate the same as Ascorbic Acid?
Otherwise this whole interview was video gold,may this doctor be healthy and keep spreading knowledge!
What an extraordinary man. Fascinating, and enormously informative.
DEFINATELY LOVE all holistic doctors helping people understand the real Importance and need for eating properly and using proper supplementation...AWESOME!!!
Great information. I only wish I would of been more informed about this years ago. Never too late.
I often daydream about what would have happened if Linus Pauling had lived another 30 years and we had his wisdom today. He would have acquired this kind of understanding that Dr. Jaffe has, coupled with the all the other analytical and pattern memory etc. etc. that made him oen of the greatest experimental scientists of all time. To any physician scientists, qualified or self-taught to that level, reading this, please mention others who you think have reached this level that Dr. Jaffe shows. I would love to have some names to go to.
Dr you gave me goosebumps, so simple yet effective explanation. God bless you.
I, Likewise previous comment below, your interview skills are brilliant. Straight to the point without fluffing about. Well done 👍🏿
Thanks for the video . Right to the point. Truly appreciate the intro/promo. 😊
The synchronicities are uncanny! I had a very physically/emotionally stressful event an hour ago. As soon as I saw my bag of goji berries, I went crazy and started gobbling goji berries like crazy, while watching the video. Once he started talking about Ascorbic Acid, I looked it up. Very rich in Ascorbic acid! 🙌🏼🙌🏼🙌🏼
Love this guy, thanks for the informative podcast!
Thank you Dr. Jaffe and Mike you're sharing your brilliance on Health and Longevity.
JP
Helpful show notes. So clear and well organized.
One thing that Dr. Jaffe left out is that it takes SEVEN zinc atoms for every metallothionein protein created. If you’re heavy metal toxic, then you’ll need at least seven zinc atoms per single heavy metal atom that you wish to remove.
That's fascinating! I'm heavy metal toxic with high levels of zinc 🤔
@@joebobmarley2854 you’ll have to find out if the zinc you are toxic with is bioavailable or biounavailable. If you’re a welder or work around/with galvanized materials, you might be loaded with zinc oxide which I infer from some studies that the body doesn’t really use (it doesn’t really affect the rate of hair growth compared to other better forms of zinc). Tons of sunscreen (the chalky white kind) and fortified foods are also other sources of zinc oxide.
From my perspective, (I had Alzheimer’s, cured myself and am now getting younger), the fastest way to roughly assess you zinc bioavailability status would be to preform an oral zinc sulphate test. If it immediately tastes very bitter, then you have sufficient bioavailable zinc. If instead you taste water, you’re likely loaded with useless biounavailable zinc.
@Taiwo Omotosho in general yes, but there are many, many nuances to it that I still have to learn. Ie. Oats, although they have many benefits, are actually highly acidic when broken down, ditto for wheat, meat and dairy.
Thank you both for that info packed interview! Mind blown...
First time I hear of this smart man, impressive.
loved all the information...thank u for sharing!!
I must admit I feel overwhelmed and all this has gone above my head!!!!!
Take a deep breath, step away for the moment, and listen and re- listen to the video. Relax don't try to comprehend everything all at once. Write down a few things you hear and feel are revelant to you. Then dive back in for more. 🙏🤗
The product of what we eat drink think and do. Absolutely brilliant Dr. Jaffe. A huge lesson in itself. Thank you gentlemen for this amazing video and life lessons.
Thank you Mike, JP
YEAH YOU! AGAIN YOU HA E THE BEST VIDEOS. NOT ONLY ARE YOU TOP NOTCH IN ALL YOU BRING Y TO THE SUBJECTS SND DISCUSSIONS, BUT ONLY THE BEST PEOPLE AS GUEST TOO! I FEEL BLESSED TO HAVE FOUND THIS WEATH OF HEALING.
Bravo for being the best host because you stay engaged, contributing but not taking over. You have an excellent grasp of keeping the program happening. Better then well done.
Do you know how they test for obsenogens? How do you test for flouride toxcity.
Thanks for posting this essential information.
WOW dr russell jaffe is genius in his knowledge i like this guy
Excellent interview. Very beneficial.
Thank you for sharing. This is wonderful
There are WAY more foods high in sulfer than what he's mentioned. All veggies in the allium genus: including but not limited to onion, garlic, chives, shallots, leeks. Also all veggies in the brassicacaea family aka cruciferous veggies including broccoli, cauliflower, collards, cabbage, bok choy, turnip, radish, etc.. Also, most meats have sulfur. Especially crab, chicken, lobster, organ meats, and others. Not sure why his list is so small.
Meat and organ meats are almost always ignored as a source of nutrition, in spite of being among the most nutrient-dense foods around.
Please have more of Dr. Jaffe.
Glad I found this video, subscribed!
Thanks, Eddie! Glad you found it, too.
Cheers,
Mike
New sub. Thank you for sharing! You both are great!
Very informative. Thank you.
Thank you so much!,,
Great interview!
HIH, thank you for the valuable notes which made it easier to understand.
Amazing! I'm inspired and motivated! Wow!
AWESOME INTERVIEW!!!!!!!
Best explanation I've heard..Superb information
Thank you! - massively informative
That old guy's hair-do looks epic from that camera angle
Funky Bee lol
Great Interview Mike! I had some crazy detox type reactions and symptoms recently when I started drinking fresh squeezed lemons daily. I had to lower the amount because I was feeling pretty sick with symptoms.. After the symptoms get better, I feel better. It's crazy how toxic my body is. It's mind blowing.
Lemons are high in histamine.
@@tigertalks1567 they are not high in histamine though they trigger the body to produce histamine.
Amazing, thank you so much for sharing! Everyone needs to see this
This is priceless, thank you!
Dr. Jaffe is GREAT!!!
Could you please put those last links Dr Jaffe mentioned at the end of this Video Information??
What about people who have mutations that make sulfur and ammonia build up in their system? I have three double mutations that do this to me and at one point I had so much ammonia in my system that I was going into liver failure from it. Lowered my levels with an infrared sauna but still a huge issue. I avoid eggs, onions, garlic like the plague.
Hi Laura. I had this issue a few years ago and tried so many food types in search of a cure, took me many years to get well. Don't worry about eggs, onions, garlic etc. Get yourself a bag of Ascorbic Acid and a bag of MSM and take generous quantities dissolved in orange juice...eat greens...reduce animal proteins (or quit)...do not eat dairy. Wish you well : )
Do you have any links to products he recommended, Native Way counter flow whey protein??
Hi, does anyone on here know whether there are any benefits to taking NAC while taking wellbutrin/bupropion for treatment of MD? many thanks.
Zinc
Magnesium
Elective protective mode to survival
Tremendous! Thanks so much.
Music to my ears...thank you 🙏💖🌷
Hello Dr Jaffe, we miss you in Houston.
So, what are those foods? Can anyone pls list them? Thank You
Hello sir what would u recommend me to raise my antibodies level??igG levels
what an amazing person!
Dr. Russell Jaffe you are brilliant! Excellent interview wonderfully placed questions designed perfectly to inform us. Thank you and I hope you invite him back now in 2022.
Curious if Glutathione is effective in patch form and does it methylate properly? The military has used these patches for soldiers in submarines for long periods of time including using stem cells in patches.
Very valuable info regarding homocystine testing.
Whats the best way to reach Dr. Jaffe?
My son-in-law was a special ops medic. I know the military has been responsible to developing some amazing medical things. Since our family eats organic I am surprised he never mentioned anything about stem cells in patches. Interesting for sure!
Ha hahaha... I love all them foods! I have always ate all them foods since my father introduced me to onion and sardine sandwich when I was preteen! Now days I just drop the bread and eat off a plate with mustard and butter!
Same here hahah. Love it
First time i ever heard of a person saying they have a hard time digesting eggs that is fascinating to me i wonder why about that
Your picture in the background isn't centered. haha Had to say it, but this was a great video!
Mark Beleski. The camera angle makes the background look off.
Whey PROTIEN is very expensive is there other ways to get this source? Thanks, Dawn
Excellent information 🙌🤩🤩
Can native whey come from fermenting raw cow or goat milk; in essence making kefir and separating whey out by straining by gravity over night.
Great information!
Does Ascorbate could be taking as a supplement or it should be through foods?
The Ginger Root Lemons and Limes and red peppers to taste with some crushed garlic glove can be blended together with some water or coconut water. Add a date or 2 with a finger size fruit of Thai Tamarind Fruit to mix all together in our blender. Pour the mixture into a large glass mason jar and add more water to the top. Your water must be filtered or boiled rainwater that we use. Place a glass lid or saucer over the mouth of the mason jar . Then place this room-temperature tea outside in your garden for some SUN exposure for a day or two. Then strain the liquid through a straining basket into another jar and refrigerate your probiotic solar herbal tea for Detox and Cleansing a therapy that the Garden Villa Phuket Thai Nature Retreat does on a regular basis. This is a good all-around tonic for your health.
What is a well-known sulphur deficiency state? The one that people obtain if they lack those recommended sulphur rich foods
do we need to do this vitamin c flush every day???
Would you consider in the pyramid of Fats that's the AHA recommended margarine and high pufa fats are the antithesis to Glutathione? Coukd you help me understand this?
I having trouble find grassfed weigh protein concentrate from native counterflow
I have intolerance to sulfur foods. Especially get severe ibs with garlic and onions.
I have learnt so much from your videos
can we perform c cleanse with perque 1000 mg c guard tabsules....if powder is not available???
Great episode the guest sounds kind of like the voice of dr. Kines Father from the audiobook of dune. 😁
What brand of Ascorbic do you recommend??
I have sulfur intolerance. I take molybdenum for two years but still have sulfur intolerance. What can I do? Thank you
Very informative lecture
I think the same thing with the vitamin c flush happens when you take nac.
So Ascorbate is active ingredient in Ascorbic Acid that needs to be reduced with catalyzers to mineral salts to act directly?
Are mineral salts of ascorbate called 'buffered vitamin C' better version of Vitamin C? Why pure ascorbate is not a thing?
I heard that people mix baking soda with l-ascorbic acid to reduce acidity and drink it, but that is a lot of sodium!
Is there a better way to cheaply make mineral salts ascorbate that contains all the proper necessary minerals?
In my exerience I found that ascorbic acid + magnesium + B6 + taurine + eggs helps a lot with hangover, especially taken during drinking.
Great information. Thank you so much. I'm curious, which is better for boosting the immune system, sodium ascorbate powder or pure ascorbic acid crystals?
Ascorbate is the true one
Just watched this video for the first time and I’m definitely going to watch it again. I had the same question as you (and many more). Have you implemented a protocol including ascorbate? Do you have a TH-cam channel or site for ripped fitness over 50?
@@amperage8032 m
Hello, Is it good to get vitamine C injection instead ? Thanks for the answer