Here's a ChatGPT summary: - Autophagy is a self-degradative process targeting damaged or aged cell constituents for degradation. - Exercise is a powerful enhancer of autophagy, influencing muscle health and longevity. - Customizing fasting protocols depends on exercise levels; more exercise may reduce the need for prolonged fasting. - Dysfunctional autophagy can lead to acute and chronic diseases like obesity, type 2 diabetes, and neurodegenerative diseases. - Both acute and chronic exercises enhance autophagy, with chronic exercise providing long-term benefits. - Overtraining can disrupt autophagy and cause cellular damage, highlighting the need for balanced exercise. - Skeletal muscle mass maintenance is linked to moderate autophagy, which is crucial for muscle function. - Exercise-induced autophagy improves mitochondrial function and muscle performance. - Cardiomyocytes (heart muscle cells) benefit significantly from autophagy, which helps maintain cardiac function and prevent heart disease. - Liver health is also improved by autophagy, which can be monitored through liver function tests. - Fasted exercise can significantly increase autophagy, promoting the breakdown of glycogen and damaged proteins. - Chronic exercise raises baseline autophagy levels, supporting long-term cellular health. - Autophagy plays a role in preventing and managing type 2 diabetes by improving mitochondrial function and insulin sensitivity. - Lipophagy, a subtype of autophagy, is crucial for fat loss and preventing obesity-related complications. - Combining exercise with calorie restriction is an effective strategy for weight loss and improving metabolic health. - Main message: Exercise is a powerful tool for enhancing autophagy, which is crucial for maintaining muscle, heart, liver, and overall cellular health, and should be combined with fasting and calorie restriction for optimal benefits.
A better prompt is • [Create a greater contextual outline using bullet points with subcategories and parenthesis for definitions pertaining to medical terminology] Gives you an easier optical summary to digest things easier. IMO not judging just offering another alternative It helps me out! ❤
Thanks for the videos on fasting. I just completed my first water-only fast and made it 60 hours. I'll try again for 120 hours in two weeks and build from there.
@@andredaedone5 Wow, I barely knew fasting was a thing that normal people did until I started following High Intensity Health and a few others over the past few years.
You sound like a MAGA supporter who doesn’t believe Biden is a genius. Biden is a super genius with superior cognitive function. He proved it in the debate. Trump is a liar by claiming 2 plus 2 is 4.
@@brianbachmeier34looking back at some photos my family took when we were at Cocoa Beach in 72, the beach was filled with relatively fit people. I went back just last month and took another photo and there were many more overweight and obese people compared to the photo taken in the 70’s. Just an observation but worth mentioning.
Great video. My personal anecdotal evidence is that exercise during a fasted state significantly increases autophagy. For the last four years I have done heavy lifting, deadlifts etc., while finishing a 16 hour fast. The results have been amazing. My friends all look old but I’ve kind of stopped time.
My results with fasting, exercise and good sleep at 74 are amazing. One year later, body fat from 31 to 26%, weight loss 155 to 137 lbs. I now have slimmer waist. I'm round where it counts. My face looks amazingly younger too. I'm eating hi-protein, mid-fat and low-carb. I'm not doing heavy, I vary my exercise routine to keep the body challenge going and I tack my food.
I do OMAD carnivore and I’m working 24 hrs fasted sometimes on my ranch at 7200 ft altitude tons of sun ketones pumping at the end of the day, good to know it’s keeping me healthy!
@@andrewrivera4029 I wouldn’t be surprised if down the line a study comes out that claims sun exposure increases ketone production and assimilation or something along those lines 😂
@@gabriel1095 no it’s the fasting that creates the ketones but I do benefit from living at altitude so when I visit back east I do not have any problems peddling mtn bike with my buddies, unfortunately there is no easy way, although bariatric therapy is extremely popular for cancer where people sleep in a high oxygen environment.
Exercise in the morning gives you energy and clarity of thought to make the most out of your day. Plus you are being rewarded with excellent health ! I learn so much from your videos during my morning routines, Thanks.
I’ve found that fasting and carnivore is very effective for weight loss & pretty easy if you drink an electrolyte drink that’s specifically for fasting. It’s surprisingly effective and easy. 👍
i do a daily TRE 16/8 since I'm prone to overindulge otherwise. Saying 'no' to my hunger for a portion of every day keeps me in control & not led by my appetites
I lost a lot of muscle by fasting for too long with a very active lifestyle. I don't workout, but I am a 50 year old contractor who walks tens of thousands of steps on an off day. I just move a lot. So I found that eating just a very small amount of hamburg, steak, chicken or clean protein like that, in the morning, both breaks my fast and also keeps my protein in good shape. I no longer 'fast' like I did but I use many of the principles that I used to use, fasting was just a part of the puzzle. I should add. I am 6 feet tall, weighed roughly 172-174 for a couple of years, then started intermittent fasting, went to 168 for a year, that's cool. Then all of the sudden I went to 164 and people were asking what was going on. I added a handful of nuts in the morning to break the fast, but then moved on to 2-3 ounces of protein so that I get better amino acids. Now I am 178, have good muscle and am feeling good.
WOW so you’re telling me you started off the day by inducing muscle protein synthesis??? It’s almost like when it comes to getting bigger body builders know what their talking about 😱
@@luisdelgado7764 I have a sister who is a spokesperson for a grocery store (dieticien/nutrician) and I trust weight lifters more than her, yes. Weightlifters actually have to get results, other people just talk, talk, talk.
You have to workout. Your body needs to know that muscle is necessary and it will make it want to hold onto it, as long as you are eating ENOUGH PROTEIN
If you don't workout....ie use your muscles, then you'll lose it, and even quicker while fasting. You say that you do lots of steps, but that's not enough. Walking doesn't put enough stress on your legs to induce muscle growth, and walking doesn't work all the muscles in your upper body.
And "guess what" "for longevity" you can finish eating early, do fitness at end of work and have a LOT MORE autophagy (during night) as you've already started it Good with the fitness
Dr. M, thank you for all the information you provide. I have listened to many of your TH-cam videos and have incorporated your suggestions. I especially love the fact that you talk about moving more and being active. I just had a checkup and my doctor told me that I am in great shape…and to keep it up. So thank you again for all you do to keep us informed about our health.
Autophagy only works at cleaning intercellular processes. The channel should also talk about the external mechanism that clean outside of the cell. That’s as important as any.
Long time faster, and definitely familiar with the unique words associated with this WOL, but sounds like the author of the book put all the fasting science words together in every sentence. If brain activity is a form of exercise, then reading the book will be like running a brain marathon! Thank you for your video to sum it all up!
Bodybuilding, we have our weeks of bulking, yes, but we do have a cutting period where we do go into a calorie deficit, especially 4 weeks out from showtime. It’s why we can drop into the single digits of body fat.
Why do so many body builders drop dead at very young ages? One of the most unhealthy pursuits. Narcissistic too. Work on strength and not a show body. Strong guys much more appealing then vain body builders, who are weaker pound for pound then your average construction worker. Building your body for show is a feminine pursuit. Not masculine at all and most look more freaky than good
I’m 5’ 11” and went from 295 to 170 five years ago. I got married 3 years ago and went back up to 215, and I’m on my way back down (currently 195). We’re working together, and are realizing just how little food we actually need to feel good and be healthy. Thank you for videos like this helping me understand better what my body’s really doing during this process, and then later as we maintain with time restricted and healthy eating. We really appreciate it:)
With my fasting routine, I find it works best when I am fairly firm but not just ridiculous about it. During my water fasts, I do allow the occasional banana or brownie, I love brownies, and by making this minor change it has helped me get through five and even six day fasts without any problem.
I over exercise quite often, especially in the ocean. Therefore I don’t fast much. Good days, I may not eat for 14 - 15 hours but most days I try to have at least 11 - 12 hours break from eating. The priority should be on my sleep first.
HIIT training should be limited to 1-2 times/ week. Resistance training should be everyday. Include weight training and body sculpting. The eating window should be 8 hours or less daily preferably a 4-6 hour eating window. Include more clean 🎉red meat. Check out Dr. Anthony Chaffee also Dr. Mindy Pelz.
I am about to finish my first ever 72 hours in about -/+ 4 hours. It has been a breeze. Constant energy, felt zero hunger. The thought of autophagy is what kept me going. I’ve already been eating high fat several years now.
Fasting and feasting, great information Mike! Autophagy is also highly anti cancer, and regenerative. Your muscle coordination will improve due to regenerating your cerebellum.
How many more ways can one verify the simple idea that, in order to go up, you must first go down? Once you see that, you can’t unsee it. Some kind of polarity governs all things in this universe. Deprivation. Pain. Deployed in smart ways, they create and build. What is anything without its opposite? Nothing at all. Unity and emptiness are the same thing. It’s why Buddha said all life is suffering. Because without tension between opposing forces, without a struggle against death, there can be no life.
3g of HMB prevents catabolism during salt water fasting while resistance training/ intense cardio on empty stomach - it is a thing - it works GREAT!!! - get to keep lean muscle mass while releasing TONS of body fat and water weight.
I really like that video Dr Mike. It accompanied me during a bit of landscaping, which was vigorous exercise, day 2 of a 72 hour fast, was perfect timing haha. I liked the way you explained the subject was very cool.
I been doing a lot about learning how everything works from many people. I guess after a year, I am upping my game of understanding. This was a good video.
My understanding is that autophagy during exercise is activated in the muscles being worked out, and therefore any effects on the brain, etc. are indirect. To activate autophagy in the brain, etc., fasting is required. Is this understanding correct?
This is an exemplary video Mike. Really thorough and balanced unlike much of the nonsense that autophagy is an ‘on/off’ process. I will need to check out that book 📖 you cited. Thanks for all you do and perhaps we’ll see you on my podcast in the future 🙏🏻
Calorie restriction is good for weight loss considering insulin levels are low. However, it should only be done very short term to prevent your metabolic rate from decreasing. 36-48 hour water only fasting done once per week will produce better results and will increase your metabolic rate without having to worry about loose skin as the fat comes off. Plus you get the benefit of boosting HGH. This is a much better option for people who are insulin resistant and are not metabolically flexible - meaning they are unable to go in and out of ketosis every 12 hours or so. Burning glycogen for fuel during the day and burning ketones from lipids at night while asleep.
Great video! Although I believe Vinnie Tortorich may have made electrolytes with Redmond’s years ago through pure vitamin club. Regardless, thanks for bringing up supplement quality!
I started working out in the morning after fasting and no meal. I am obese. I work out at 7am in the morning and have my first meal around 11:30am. is that okay? like I said before I am obese. but I can walk many miles and work out cardio and some muscle for 20 minutes. I also have multiple sclerosis.
I’ve been IF for 45 days and lost 20 pounds so far. I’ve been training with weight also, alternate days. I’m feeling very good! Carnivore in my eating window , specially fish mixed with green leaves only.
In other words, working out physically.Exerting yourself while starving on some occasions Speeds of autophagy it may actually increase your vascular health and increase overall circulatory health
Would love to see more variety of flavors in the styx. Been using both yours and LMNT, but prefer their flavors. (Seems petty, I know). I like the fact that I know you have real salt in yours.
During my 51 day water fast, I had a hard time exercising. I would get out of breath quickly and had trouble with balance. I noticed a similar effect on my current diet (Lion's Diet) The solution? Vitamin C. After supplementing with C for awhile, I noticed my respiration has improved significantly. I now am back to exercising and my performance is through the roof. Interestingly, on the Lion Diet I don't experience DOMS. I'm not sore for days after working out. So I'm able to push even further
Wow 51 days? That's something you really have to be careful with. Actual starvation and muscle/organ wasting. Do you have a lot of excess weight to use as energy?
51 day water fast!? You know your body better than I do, but I'd take a wellness break every 14 days and keep it going after making sure my functioning was optimal.
@@BBWahoo My only regret is the muscle loss. It was an incredible experience and had a lot of benefits. I’m on the Lion’s Diet now, which mimics the effects but also allows me to build muscle
It's rare I get healthy info that works well with my current workout routine. I've already been scheduling cardio days as a sort of active rest day for weight training. One was a VO2 max training day and the other was just endurance cardio, but now I can make it a fasted cardio day.
I just completed 120 hrs water fast …..finished Friday ….it was tough ….but have been feeling great since ….not sure how often this should be repeated …more info on this would be great 🙏
Once per month, five day water fast would make you bulletproof. You could eat, drink anything you want. Rhonda Patrick mentions this in a interview with Longo.
I got my blood work this week, the first time in 18 years. I am a little acidosis and being Carnivore I introduced a few high ph foods and baking soda into my diet. My triglycerides and LDL were high so I am going into a fast for autophagy next week. I will try for five days. I also introduced prebiotics not probiotics in my diet. I normally fast everyday for 18 hours. I will say this is my one year Carnivore maintenance cycle. I exercise like a maniac.
I take my supplements first thing in the morning and then have a cup of black coffee. Do my supplements break my fast? More specifically, do my beef organ and cod liver supplements technically break my fast? I don't eat my first meal for several hours after waking.
I take supplements in fasting window and still lose weight. Unless I forgot, I take them at the very end of my eating window, advice per Dr. Wendy Pelez in “Fast Like a Girl,” for best fortification from hair loss. If I forgot, I take them while fasting, still lose weight, and I don’t worry about it.
I didn't know any of this. However, over the last 3 weeks I've been having my last meal by 8pm, and the start kettlebell workouts between 10am - 1pm (~30mins actual workout time) then eat at 4pm. I target different areas of my body each day. How do I know if I am exercising too much?
When I do a fast from 7 pm to 8 am, it is a 12 hour fast. However, at bedtime I take a sleeping aid supplement which contains glycine, taurine, GABA, theanine, choline, calcium Pantothenate, and 5 mg of glucose. Does the 5 mg of glucose take me out of a fasted state??!!
how much is to much? i lift 5 days a week for 1 1/2 hours and15 cardio before and after and a cardio day including 30 min cycle and 30 min rebound and a hike. then one day off.
2:11 the organ systems that were designed lol because if we didn't have these functions, and we had to wait thousands of years for each organ to somehow form itself, the species would have never continued. Just like that random fish that washed up on shore that somehow could breathe and feed itself, on land, to give itself enough energy to reproduce with itself even though it didn't have that function. It would have died and evolution would have never happened if that were the case. It's funny that Google will say that your shoulder muscles evolved from the oblique muscles but how would you have been able to feed yourself if you couldn't lift your arm (ou need food for energy to reproduce)?How would you have been able to feed yourself with proper foods if you didn't have working memory to begin with to remember what foods to eat and what foods not to eat, as well as to remember that eating is going to get rid of that hunger feeling you somehow didn't know you had? When you take the reality-test, it's so easy to disprove Evolution over and over again. How would our bodies have even been able to form mitochondria if we couldn't live without it to begin with? I know this has nothing to do with the video but I still have to take advantage of opportunities to remind people that every system in our body had to function immediately so that we were able to survive adapt and thrive, otherwise every last species in the world would have died off before it had the chance to reproduce because the reproduction of code itself is a design
Minimising insulin promotes autophagy on the carnivore diet .Fasting isn't necessary .Bodybuilders eat Processed carbs that mess with their blood sugars and insulin , so autophagy deficit is the least of their problems, (compared to insulin resistance wrecking arteries).
Here's a ChatGPT summary:
- Autophagy is a self-degradative process targeting damaged or aged cell constituents for degradation.
- Exercise is a powerful enhancer of autophagy, influencing muscle health and longevity.
- Customizing fasting protocols depends on exercise levels; more exercise may reduce the need for prolonged fasting.
- Dysfunctional autophagy can lead to acute and chronic diseases like obesity, type 2 diabetes, and neurodegenerative diseases.
- Both acute and chronic exercises enhance autophagy, with chronic exercise providing long-term benefits.
- Overtraining can disrupt autophagy and cause cellular damage, highlighting the need for balanced exercise.
- Skeletal muscle mass maintenance is linked to moderate autophagy, which is crucial for muscle function.
- Exercise-induced autophagy improves mitochondrial function and muscle performance.
- Cardiomyocytes (heart muscle cells) benefit significantly from autophagy, which helps maintain cardiac function and prevent heart disease.
- Liver health is also improved by autophagy, which can be monitored through liver function tests.
- Fasted exercise can significantly increase autophagy, promoting the breakdown of glycogen and damaged proteins.
- Chronic exercise raises baseline autophagy levels, supporting long-term cellular health.
- Autophagy plays a role in preventing and managing type 2 diabetes by improving mitochondrial function and insulin sensitivity.
- Lipophagy, a subtype of autophagy, is crucial for fat loss and preventing obesity-related complications.
- Combining exercise with calorie restriction is an effective strategy for weight loss and improving metabolic health.
- Main message: Exercise is a powerful tool for enhancing autophagy, which is crucial for maintaining muscle, heart, liver, and overall cellular health, and should be combined with fasting and calorie restriction for optimal benefits.
Thanks a lot.
A better prompt is
• [Create a greater contextual outline using bullet points with subcategories and parenthesis for definitions pertaining to medical terminology]
Gives you an easier optical summary to digest things easier. IMO not judging just offering another alternative
It helps me out! ❤
You rock!!
TY!!
Whew! Thank you, listening to his sentences quoted from the was exhausting!
Good on you for pointing out a very important irony; overexercise can cause more harm than good
Thanks for the videos on fasting. I just completed my first water-only fast and made it 60 hours. I'll try again for 120 hours in two weeks and build from there.
The most i ever did was 40 and i felt pretty good. Yesterday in did 21
I used to fast for up to two weeks when I was in my 30's. Now almost 70, it seems to be a lot harder. I will go for five days next week.
@@mark2073being a Carnivore I do 18 hours everyday and for a while I was fasting on Mondays from Sunday night until Tuesday afternoon.
@@andredaedone5 Wow, I barely knew fasting was a thing that normal people did until I started following High Intensity Health and a few others over the past few years.
I feel great eating once a day
Make Health Great Again
You sound like a MAGA supporter who doesn’t believe Biden is a genius. Biden is a super genius with superior cognitive function. He proved it in the debate. Trump is a liar by claiming 2 plus 2 is 4.
Boo, health was never good in the USA. So it only gets better every year.
@@ComputersAndLife Really? What's the percentage of people are obese?
@@brianbachmeier34looking back at some photos my family took when we were at Cocoa Beach in 72, the beach was filled with relatively fit people. I went back just last month and took another photo and there were many more overweight and obese people compared to the photo taken in the 70’s. Just an observation but worth mentioning.
@@ComputersAndLifeyou need to lay off the crack! We've never been MORE unhealthy, ever!
Great video. My personal anecdotal evidence is that exercise during a fasted state significantly increases autophagy. For the last four years I have done heavy lifting, deadlifts etc., while finishing a 16 hour fast. The results have been amazing. My friends all look old but I’ve kind of stopped time.
My results with fasting, exercise and good sleep at 74 are amazing. One year later, body fat from 31 to 26%, weight loss 155 to 137 lbs. I now have slimmer waist. I'm round where it counts. My face looks amazingly younger too. I'm eating hi-protein, mid-fat and low-carb. I'm not doing heavy, I vary my exercise routine to keep the body challenge going and I tack my food.
I do OMAD carnivore and I’m working 24 hrs fasted sometimes on my ranch at 7200 ft altitude tons of sun ketones pumping at the end of the day, good to know it’s keeping me healthy!
What are sun ketones?
@@k14michael aliens
@@k14michael sorry, punctuation: tons of sun, ketones…
@@andrewrivera4029 I wouldn’t be surprised if down the line a study comes out that claims sun exposure increases ketone production and assimilation or something along those lines 😂
@@gabriel1095 no it’s the fasting that creates the ketones but I do benefit from living at altitude so when I visit back east I do not have any problems peddling mtn bike with my buddies, unfortunately there is no easy way, although bariatric therapy is extremely popular for cancer where people sleep in a high oxygen environment.
Exercise in the morning gives you energy and clarity of thought to make the most out of your day. Plus you are being rewarded with excellent health ! I learn so much from your videos during my morning routines, Thanks.
Morning exercise is the ultimate self-love & gratitude practice- at the end of physical exertion we reach the spiritual
I’ve found that fasting and carnivore is very effective for weight loss & pretty easy if you drink an electrolyte drink that’s specifically for fasting. It’s surprisingly effective and easy. 👍
What drink do u suggest
@@joeybloggs6357I want to know too!!
@@joeybloggs6357snake juice apple cider potassium salt and water
I’m getting back into my extended, prolonged fasts of 24+ hours. I feel it helps w my fat loss
i do a daily TRE 16/8 since I'm prone to overindulge otherwise. Saying 'no' to my hunger for a portion of every day keeps me in control & not led by my appetites
@@luzaguirre2830What is TRE?
@@kittendkat5100
time restricted eating
@@luzaguirre2830 got it, thanks
I lost a lot of muscle by fasting for too long with a very active lifestyle. I don't workout, but I am a 50 year old contractor who walks tens of thousands of steps on an off day. I just move a lot. So I found that eating just a very small amount of hamburg, steak, chicken or clean protein like that, in the morning, both breaks my fast and also keeps my protein in good shape. I no longer 'fast' like I did but I use many of the principles that I used to use, fasting was just a part of the puzzle.
I should add. I am 6 feet tall, weighed roughly 172-174 for a couple of years, then started intermittent fasting, went to 168 for a year, that's cool. Then all of the sudden I went to 164 and people were asking what was going on. I added a handful of nuts in the morning to break the fast, but then moved on to 2-3 ounces of protein so that I get better amino acids. Now I am 178, have good muscle and am feeling good.
I bet you look good too
WOW so you’re telling me you started off the day by inducing muscle protein synthesis???
It’s almost like when it comes to getting bigger body builders know what their talking about 😱
@@luisdelgado7764 I have a sister who is a spokesperson for a grocery store (dieticien/nutrician) and I trust weight lifters more than her, yes. Weightlifters actually have to get results, other people just talk, talk, talk.
You have to workout. Your body needs to know that muscle is necessary and it will make it want to hold onto it, as long as you are eating ENOUGH PROTEIN
If you don't workout....ie use your muscles, then you'll lose it, and even quicker while fasting. You say that you do lots of steps, but that's not enough. Walking doesn't put enough stress on your legs to induce muscle growth, and walking doesn't work all the muscles in your upper body.
And "guess what" "for longevity" you can finish eating early, do fitness at end of work and have a LOT MORE autophagy (during night) as you've already started it Good with the fitness
Dr. M, thank you for all the information you provide. I have listened to many of your TH-cam videos and have incorporated your suggestions. I especially love the fact that you talk about moving more and being active. I just had a checkup and my doctor told me that I am in great shape…and to keep it up. So thank you again for all you do to keep us informed about our health.
Autophagy only works at cleaning intercellular processes. The channel should also talk about the external mechanism that clean outside of the cell. That’s as important as any.
Could you explain this like i'm 5?
Long time faster, and definitely familiar with the unique words associated with this WOL, but sounds like the author of the book put all the fasting science words together in every sentence. If brain activity is a form of exercise, then reading the book will be like running a brain marathon! Thank you for your video to sum it all up!
This message is one of your most important. You hit on all the key points.
Bodybuilding, we have our weeks of bulking, yes, but we do have a cutting period where we do go into a calorie deficit, especially 4 weeks out from showtime. It’s why we can drop into the single digits of body fat.
Why do so many body builders drop dead at very young ages? One of the most unhealthy pursuits. Narcissistic too. Work on strength and not a show body. Strong guys much more appealing then vain body builders, who are weaker pound for pound then your average construction worker. Building your body for show is a feminine pursuit. Not masculine at all and most look more freaky than good
I’m 5’ 11” and went from 295 to 170 five years ago. I got married 3 years ago and went back up to 215, and I’m on my way back down (currently 195). We’re working together, and are realizing just how little food we actually need to feel good and be healthy. Thank you for videos like this helping me understand better what my body’s really doing during this process, and then later as we maintain with time restricted and healthy eating. We really appreciate it:)
With my fasting routine, I find it works best when I am fairly firm but not just ridiculous about it. During my water fasts, I do allow the occasional banana or brownie, I love brownies, and by making this minor change it has helped me get through five and even six day fasts without any problem.
Yes. Eating really does make the fast easier.
Are you trolling? Eating during your fast?? 😂
😂😂😂
Eating means not fasting. You’ve got to be joking? Please be.
I eat triple cheese burger in my fast as it helps me get through… good luck kings
I over exercise quite often, especially in the ocean. Therefore I don’t fast much. Good days, I may not eat for 14 - 15 hours but most days I try to have at least 11 - 12 hours break from eating. The priority should be on my sleep first.
HIIT training should be limited to 1-2 times/ week. Resistance training should be everyday. Include weight training and body sculpting. The eating window should be 8 hours or less daily preferably a 4-6 hour eating window. Include more clean 🎉red meat. Check out Dr. Anthony Chaffee also Dr. Mindy Pelz.
Bonk training. It’s what makes the last 6.2 of a marathon such a blast. Gotta take it down to the studs sometimes. You’ll find they’re made of steel.
I am about to finish my first ever 72 hours in about -/+ 4 hours. It has been a breeze. Constant energy, felt zero hunger. The thought of autophagy is what kept me going. I’ve already been eating high fat several years now.
Fasting and feasting, great information Mike! Autophagy is also highly anti cancer, and regenerative. Your muscle coordination will improve due to regenerating your cerebellum.
How many more ways can one verify the simple idea that, in order to go up, you must first go down? Once you see that, you can’t unsee it. Some kind of polarity governs all things in this universe. Deprivation. Pain. Deployed in smart ways, they create and build. What is anything without its opposite? Nothing at all. Unity and emptiness are the same thing. It’s why Buddha said all life is suffering. Because without tension between opposing forces, without a struggle against death, there can be no life.
Thanks Mike! 🙂
Mike awesome job, but important thing that was left out. Fasting will naturally increase growth hormones inside for weight lifting
Exercise depletes l-carnitine. It is used for fat adaptation and metabolism. I would supplement that when fasting.
3g of HMB prevents catabolism during salt water fasting while resistance training/ intense cardio on empty stomach - it is a thing - it works GREAT!!! - get to keep lean muscle mass while releasing TONS of body fat and water weight.
I've always found that fasting is more effective when you don't eat.
I call it starving
Fasting is too much. I like slowing.
What?! Fasting is not eating!
@@0ptimal
Where is cheat sheet for lab work my brother , didn’t se it , thanks so much , great info and channel , God bless
Any research on effects of prolonged water fast with different metabolic diseases? 7 days to 40 days water fast
Great information! Thank you!
I really like that video Dr Mike. It accompanied me during a bit of landscaping, which was vigorous exercise, day 2 of a 72 hour fast, was perfect timing haha. I liked the way you explained the subject was very cool.
I been doing a lot about learning how everything works from many people. I guess after a year, I am upping my game of understanding. This was a good video.
My understanding is that autophagy during exercise is activated in the muscles being worked out, and therefore any effects on the brain, etc. are indirect. To activate autophagy in the brain, etc., fasting is required. Is this understanding correct?
i needed to hear this. gonna start doing my zone 2 and 4x4 fasted again.
This is an exemplary video Mike. Really thorough and balanced unlike much of the nonsense that autophagy is an ‘on/off’ process. I will need to check out that book 📖 you cited. Thanks for all you do and perhaps we’ll see you on my podcast in the future 🙏🏻
Calorie restriction is good for weight loss considering insulin levels are low. However, it should only be done very short term to prevent your metabolic rate from decreasing. 36-48 hour water only fasting done once per week will produce better results and will increase your metabolic rate without having to worry about loose skin as the fat comes off. Plus you get the benefit of boosting HGH. This is a much better option for people who are insulin resistant and are not metabolically flexible - meaning they are unable to go in and out of ketosis every 12 hours or so. Burning glycogen for fuel during the day and burning ketones from lipids at night while asleep.
Great video! Although I believe Vinnie Tortorich may have made electrolytes with Redmond’s years ago through pure vitamin club. Regardless, thanks for bringing up supplement quality!
I started working out in the morning after fasting and no meal. I am obese. I work out at 7am in the morning and have my first meal around 11:30am. is that okay? like I said before I am obese. but I can walk many miles and work out cardio and some muscle for 20 minutes. I also have multiple sclerosis.
This is awesome thank
You!!
I’ve been IF for 45 days and lost 20 pounds so far. I’ve been training with weight also, alternate days. I’m feeling very good! Carnivore in my eating window , specially fish mixed with green leaves only.
Where is the bloodwork paper to give our dr? Great video
Can GKI be a measure for Autophagy? Low insulin levels? Any research?
Always great info
I was overweight, I went on OMAD and regular exercising and loss 3 stones but now I have baggy skin. I'm 71 y skin is no longer elastic.
Thank you 🙏🏿
We love ya Mike -
Great video, Mike
Thank you
In other words, working out physically.Exerting yourself while starving on some occasions Speeds of autophagy it may actually increase your vascular health and increase overall circulatory health
Would love to see more variety of flavors in the styx. Been using both yours and LMNT, but prefer their flavors. (Seems petty, I know). I like the fact that I know you have real salt in yours.
During my 51 day water fast, I had a hard time exercising. I would get out of breath quickly and had trouble with balance. I noticed a similar effect on my current diet (Lion's Diet)
The solution? Vitamin C. After supplementing with C for awhile, I noticed my respiration has improved significantly. I now am back to exercising and my performance is through the roof. Interestingly, on the Lion Diet I don't experience DOMS. I'm not sore for days after working out. So I'm able to push even further
Oh and I realize that the trouble with balance is because of losing muscle from fasting lol
Wow 51 days?
That's something you really have to be careful with. Actual starvation and muscle/organ wasting. Do you have a lot of excess weight to use as energy?
@@grantlawrence4600 Yes, plenty of excess weight. So the prolonged fast was necessary. I would be bed bound if I hadn’t started fasting
51 day water fast!? You know your body better than I do, but I'd take a wellness break every 14 days and keep it going after making sure my functioning was optimal.
@@BBWahoo My only regret is the muscle loss. It was an incredible experience and had a lot of benefits. I’m on the Lion’s Diet now, which mimics the effects but also allows me to build muscle
Where is your bloodwork cheat sheet?
Excellent share 👊🏾
Great Work!
Read "THE SWITCH" by James W Clement. Total autophagy explanation!
It's rare I get healthy info that works well with my current workout routine.
I've already been scheduling cardio days as a sort of active rest day for weight training. One was a VO2 max training day and the other was just endurance cardio, but now I can make it a fasted cardio day.
I just completed 120 hrs water fast …..finished Friday ….it was tough ….but have been feeling great since ….not sure how often this should be repeated …more info on this would be great 🙏
Once per month, five day water fast would make you bulletproof.
You could eat, drink anything you want.
Rhonda Patrick mentions this in a interview with Longo.
How fat you are is your guide, fast often till you reach correct mass
Please make a video about low iron!!
I got my blood work this week, the first time in 18 years. I am a little acidosis and being Carnivore I introduced a few high ph foods and baking soda into my diet. My triglycerides and LDL were high so I am going into a fast for autophagy next week. I will try for five days. I also introduced prebiotics not probiotics in my diet. I normally fast everyday for 18 hours. I will say this is my one year Carnivore maintenance cycle. I exercise like a maniac.
I take my supplements first thing in the morning and then have a cup of black coffee. Do my supplements break my fast? More specifically, do my beef organ and cod liver supplements technically break my fast? I don't eat my first meal for several hours after waking.
Im not certain but pretty sure ive heard that anything besides water breaks a fast.
Coffee, fat break the fast.
ANY CALORIES break a fast, probably why you're not seeing results.
I take supplements in fasting window and still lose weight. Unless I forgot, I take them at the very end of my eating window, advice per Dr. Wendy Pelez in “Fast Like a Girl,” for best fortification from hair loss. If I forgot, I take them while fasting, still lose weight, and I don’t worry about it.
Doing a 24 hour fast as I listen!
Same!
I didn't know any of this. However, over the last 3 weeks I've been having my last meal by 8pm, and the start kettlebell workouts between 10am - 1pm (~30mins actual workout time) then eat at 4pm. I target different areas of my body each day. How do I know if I am exercising too much?
The study on atophogy referenced 24 hours, but was in mice...what would be a similar length of time for humans? It would seem like maybe 4 or 5 days?
When I do a fast from 7 pm to 8 am, it is a 12 hour fast. However, at bedtime I take a sleeping aid supplement which contains glycine, taurine, GABA, theanine, choline, calcium Pantothenate, and 5 mg of glucose. Does the 5 mg of glucose take me out of a fasted state??!!
Yes
@@chrisvoss451 UGH!
Thoughts on dry fasting?
I wouldn't mind dry hoomping
Following
So is too much autophagy bad, or is high levels of autophagy without an antique nutritional replacement bad?
Thanks Mike. I've been doing the metabolic Mike early time restricted feeding for a while now. 😊
So should I be exercising fasted to get the best results?
Anyone think armless Palmer stops autophagy? It’s a drink with a tiny bit of agave nectar.
It does break the fast & autophagy.
What don't you dummies understand about NO CALORIES.
JESUS CHRIST.
how much is to much? i lift 5 days a week for 1 1/2 hours and15 cardio before and after and a cardio day including 30 min cycle and 30 min rebound and a hike. then one day off.
I have heard it said by a famous longevity doctor that autophagy only occurs in long term fasting. Is this true?
I’m actually lysing my misfolded proteins as I type this
Nobody talks about when not to fast. About 12% of people have ACAT1-02 genetic mutation. For them keto and fasting is a bad idea.
how do you fix lesions from to much exercise?
I guess I’m not understanding the Stix deal. Either the website isn’t processing the 2nd box or I’m not understanding how to do that.
Love your vids man !!!!!
Where, though, does it all start... isn't in a lot of digestión
Creatinine ok during fast?
Great lighting!
Can someone give the main idea or summary that answers the title
Discount code is valid till ? I tried it but it failed. Tks anyway
Fasting is an interesting experience. 3 to 5 days is not that difficult. 👌
The book costs almost $300.00 on Amazon
Pro metabolic people are saying you shouldn't fast but i think they're confusing fasting with not getting enough calories
You need to pray when you fast.
That's what fasting is for 🙄
pray to satan
The real power
Does drinking the electrolyte stix break a fast?
Read labels if it has calories or sugar yes
Does the equally apply to people over 65 years old?
Eat well..train well...sleep well...
Eat between 1030am and 330pm every day and workout @4am
👍 give 👍 a 👍 like 👍 for 👍 Mike! 👍
8:54 and watching Vitamin D levels 4 times a year
How do we know what the the line is that crosses over into over-training? I'm sure it's different for each individual. How would one know??
2:11 the organ systems that were designed lol because if we didn't have these functions, and we had to wait thousands of years for each organ to somehow form itself, the species would have never continued. Just like that random fish that washed up on shore that somehow could breathe and feed itself, on land, to give itself enough energy to reproduce with itself even though it didn't have that function. It would have died and evolution would have never happened if that were the case.
It's funny that Google will say that your shoulder muscles evolved from the oblique muscles but how would you have been able to feed yourself if you couldn't lift your arm (ou need food for energy to reproduce)?How would you have been able to feed yourself with proper foods if you didn't have working memory to begin with to remember what foods to eat and what foods not to eat, as well as to remember that eating is going to get rid of that hunger feeling you somehow didn't know you had? When you take the reality-test, it's so easy to disprove Evolution over and over again. How would our bodies have even been able to form mitochondria if we couldn't live without it to begin with?
I know this has nothing to do with the video but I still have to take advantage of opportunities to remind people that every system in our body had to function immediately so that we were able to survive adapt and thrive, otherwise every last species in the world would have died off before it had the chance to reproduce because the reproduction of code itself is a design
I can guess with 100 percent certainly that you are a Christian and a creationist, right?
Has this been tested on women?
Minimising insulin promotes autophagy on the carnivore diet .Fasting isn't necessary .Bodybuilders eat Processed carbs that mess with their blood sugars and insulin , so autophagy deficit is the least of their problems, (compared to insulin resistance wrecking arteries).
Wow. The book cost $90!
🇮🇱
Kayla Cox walks six miles a day and fasts...
Don't you think a low protein meal helps fasting???
Doesn't melatonin clean out mitochondria?
3 year deep still dont have my smell or taste back fully. Maybe 20% atleast I can't smell skunk..
Take this sub