The Forgotten Fruit Behind the Fight Against Leprosy - CHAULMOOGRA FRUIT (History Unpeeled)

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  • เผยแพร่เมื่อ 2 ส.ค. 2024
  • Episode: 777 Chaulmoogra
    Species: Hydnocarpus sp.
    Location: Bangkok, Thailand & NYC, USA
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    + MUSIC:
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    Licensed under Creative Commons: By Attribution 3.0 License
    creativecommons.org/licenses/b...
    ---
    Sources
    www.webmd.com/vitamins/ai/ing...
    archive.org/details/americand...
    confusion with gynocardia odorta, still goes on today, researchgate.net gets it wrong..
    www.austriaca.at/0xc1aa500d_0...
    www.statista.com/statistics/8...
    theconversation.com/humans-ga...
    www.cdc.gov/leprosy/symptoms/...
    www.britannica.com/science/le...
    www.cdc.gov/leprosy/world-lep...
    a bit about g. odorata
    medicineonscreen.nlm.nih.gov/...
    www.nytimes.com/1924/07/14/ar...
    www.latimes.com/archives/la-x...
    ---
    Chapters
    0:00-2:34 What does chaulmoogra fruit taste like?
    2:34-4:12 The legend of how chaulmoogra was discovered
    4:12-7:21 What is leprosy?
    7:21-13:45 The Social Stigma about Leprosy Past and Present
    13:45-19:10 How Leprosy used to be treated
    19:10-23:49 Traditional use of chaulmoogra oil
    23:49-27:00 How Chaulmoogra was introduced to the West
    27:00-29:53 Chaulmoogra Seed review
    29:53-36:18 Alice Ball and an improved leprosy medication
    36:18-39:14 Moogral Review, a manufactured medicine for leprosy
    39:14-41:49 How Chaulmoogra Fruit came to be grown in the USA
    41:49-47:23 The Problem with Chaulmoogra Oil
    47:23-51:08 How Leprosy is cured today
    51:08-54:41 Will there ever be an end to Leprosy?
    54:41-57:15 How Leprosy will be defeated
    + SPECIAL THANKS:
    Smarter Every Day, Joseph McCorkle, Bill T
  • บันเทิง

ความคิดเห็น • 580

  • @WeirdExplorer
    @WeirdExplorer  หลายเดือนก่อน +36

    If you enjoyed this and want to see another history heavy episode, check out my 5 part series on the Coco de Mer! th-cam.com/video/GqicsIDYmgU/w-d-xo.html

    • @aryanprivilege9651
      @aryanprivilege9651 หลายเดือนก่อน

      The information is wrong, mycobacterium are super resistant to whole body of PO antibiotics. Gram negative and positives are different in extremes solubility through wax coating, Bell’s input is unfortunately not significant and can be accessed or figured out in minutes. Know the chemical you have the solubility. It’s that she had a minor admixture of African blood in minor and female that this is artificially lionized. Especially in absence of many. The toxicity of these uv antibiotics is serious as the illnesses. I was attacked in the bandit lands of mountain to rainforest Pacific Ocean zone in indigenous communities post war. No laboratory antibiotics sensitivity tests just trail by error, no internet there police clinicians. I was a foreigner only speaking native language English. I’d mastered Spanish in 3 months there the language of nation whoch many Indios couldn’t speak and had dozens of own languages and groups not aware of a pidgin or would have quickly picked it up. It was so bad on thigh was to femur, left limped out to where legends started typical of superstition in population. Most had not seen a tall pale blonde blue eyed strong human. None certainly that would even speak to the lowest caste or be kind weep for dead, give blood or cheap meds too. Told I was one of few Northern Americans ever to go that weren’t Canadian or European. Parents were European. The smell of this infection is a foul sort of anaerobic hard to explain. Not leprosy! Though been through other tuberculosis epidemics never had bovine. Luckily doctor had read article and heard story of crazy Indios and person who couldn’t exist, could read their glyphs knew history saved them and was so prophetic blah blah said walked out of ocean returned but swam often so just error or disappeared into dark forest. Which could be mistaken from me taking path out of area to roads where go ride into next town to bus to retrace steps 2000 km to city airport next country fly home. Argentine MD said you were near there was just thinking about you, when showed leg he hit emotional asked me to wait outside office and called doctors said you will see him today. If you do not take his money to do you job, no excuses and he loses leg or life. I assure you I will see you ruined and we will both be surely damned. He apologized for years of “ mistreatment,” had met my mother which destroyed many people. Said would honor medical calls Rx requests and make it up too me? Doctors tropical medicine only recalled Cade as was so rare and name was so extraordinary, wanted to write story down, heard before. IV in patient cleared it, knock on likes cancer inducing, one so far. Lost benefits and insurance still as being persecuted over other issues helping folks research didn’t like, banks wealth pharmaceutical governments and what cannot mention. About a war. Not interesting story but happened have had infinitely more horrible or seen things photographed lectured few times on pretty much secret it disbelieved. But matters of public record. Easy to verify. I never researched this as was too busy in large efforts of research far more pressing, human crisis…I’m certain may still kill me before recover millions stolen by step brother and others from other work. I’m fairly certain it’s only 9 banded armadillo or one species unlikely vector of human zoonotic think remember from comparative vertebrate anatomy physiology or bacteriology maybe micro? I did zero research this is off the top of head. Folks don’t put any plants in mouth to skin. Phytotoxins are designed to drop you, stop you eating them by any many necessary like mycotoxins on fungi, venom etc…The microbes of our planet have been on constant accelerating warfare eternal struggles over killing controlling or keeping area food resources and competition to low or none. But we benefit in their arms races. There are trees near you that are do dangerous they are illegal or require signs, not supposed to touch or shelter under, sleep near. Never mind eat, ie saw a manzanita or little death apple other day in mangrove and city. Common you probably know, like drugs, Angel trumpets ☠️ & death caps, daturas, pseudo Tropanes alkaloids, drugs drug precursors, opio, opium. Heard expert on ibogaine say it was in Africa, Rohan said similar but always wto g like fentanylogues info are wrong 100% time. It experts and absurd. I solved this will not let me release it. Iboggain DMTs rest are surely local thought of several can walk to or get a garden store, botanical gardens or hybridized self. Trust nobody especially if say it cannot be done. That’s a challenge to disprove. Poor research or just plagerism is whatever you wish too call it, it was I believe entertaining. I’ve never taken any botany. Never offered when had opportunity. My immunity to major human killers may too die with me and few others who carry the protein coat. Other gifts, of evolution gotta explain function of allergies now, then find chemicals likely funeral or doctor visit meds that are money or life rico class organized crime crooked act. Cartels aren’t this bad as met in Puerto Arrista and Zipolite. Hope if read unlikely not offended as not my intent. Disclaimers verify all for self, host did also make proper disclaimers!

    • @aryanprivilege9651
      @aryanprivilege9651 หลายเดือนก่อน

      I know that no poco loco in the coco! If go to source, smuggle me a palm or nut. Floated here I’ll claim in post. Collected 100s as walked earth, sister cut them down extinct or one of kind hybrids maybe 3 left. But as Hass Avolcado one saves all. None shall mine! Might tear out my transplanted Sri. L. E. coca tonight.

    • @johnmchumphreson7095
      @johnmchumphreson7095 หลายเดือนก่อน

      Can I sit next to an armadillo on a plane, though?

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +2

      @@johnmchumphreson7095 yes. just don't drink its soda

    • @dannydetonator
      @dannydetonator หลายเดือนก่อน +2

      @aryanprivilege9651
      Read your own post again. And next time avoid DMT before writing anything public, if you're indeed a native anglophone.

  • @-7070
    @-7070 หลายเดือนก่อน +244

    The most impressive part about this entire story was how much research you put into it, major credit to you. Super interesting video

    • @aryanprivilege9651
      @aryanprivilege9651 หลายเดือนก่อน

      The information is wrong, mycobacterium are super resistant to whole body of PO antibiotics. Gram negative and positives are different in extremes solubility through wax coating, Bell’s input is unfortunately not significant and can be accessed or figured out in minutes. Know the chemical you have the solubility. It’s that she had a minor admixture of African blood in minor and female that this is artificially lionized. Especially in absence of many. The toxicity of these uv antibiotics is serious as the illnesses. I was attacked in the bandit lands of mountain to rainforest Pacific Ocean zone in indigenous communities post war. No laboratory antibiotics sensitivity tests just trail by error, no internet there police clinicians. I was a foreigner only speaking native language English. I’d mastered Spanish in 3 months there the language of nation whoch many Indios couldn’t speak and had dozens of own languages and groups not aware of a pidgin or would have quickly picked it up. It was so bad on thigh was to femur, left limped out to where legends started typical of superstition in population. Most had not seen a tall pale blonde blue eyed strong human. None certainly that would even speak to the lowest caste or be kind weep for dead, give blood or cheap meds too. Told I was one of few Northern Americans ever to go that weren’t Canadian or European. Parents were European. The smell of this infection is a foul sort of anaerobic hard to explain. Not leprosy! Though been through other tuberculosis epidemics never had bovine. Luckily doctor had read article and heard story of crazy Indios and person who couldn’t exist, could read their glyphs knew history saved them and was so prophetic blah blah said walked out of ocean returned but swam often so just error or disappeared into dark forest. Which could be mistaken from me taking path out of area to roads where go ride into next town to bus to retrace steps 2000 km to city airport next country fly home. Argentine MD said you were near there was just thinking about you, when showed leg he hit emotional asked me to wait outside office and called doctors said you will see him today. If you do not take his money to do you job, no excuses and he loses leg or life. I assure you I will see you ruined and we will both be surely damned. He apologized for years of “ mistreatment,” had met my mother which destroyed many people. Said would honor medical calls Rx requests and make it up too me? Doctors tropical medicine only recalled Cade as was so rare and name was so extraordinary, wanted to write story down, heard before. IV in patient cleared it, knock on likes cancer inducing, one so far. Lost benefits and insurance still as being persecuted over other issues helping folks research didn’t like, banks wealth pharmaceutical governments and what cannot mention. About a war. Not interesting story but happened have had infinitely more horrible or seen things photographed lectured few times on pretty much secret it disbelieved. But matters of public record. Easy to verify. I never researched this as was too busy in large efforts of research far more pressing, human crisis…I’m certain may still kill me before recover millions stolen by step brother and others from other work. I’m fairly certain it’s only 9 banded armadillo or one species unlikely vector of human zoonotic think remember from comparative vertebrate anatomy physiology or bacteriology maybe micro? I did zero research this is off the top of head. Folks don’t put any plants in mouth to skin. Phytotoxins are designed to drop you, stop you eating them by any many necessary like mycotoxins on fungi, venom etc…The microbes of our planet have been on constant accelerating warfare eternal struggles over killing controlling or keeping area food resources and competition to low or none. But we benefit in their arms races. There are trees near you that are do dangerous they are illegal or require signs, not supposed to touch or shelter under, sleep near. Never mind eat, ie saw a manzanita or little death apple other day in mangrove and city. Common you probably know, like drugs, Angel trumpets ☠️ & death caps, daturas, pseudo Tropanes alkaloids, drugs drug precursors, opio, opium. Heard expert on ibogaine say it was in Africa, Rohan said similar but always wto g like fentanylogues info are wrong 100% time. It experts and absurd. I solved this will not let me release it. Iboggain DMTs rest are surely local thought of several can walk to or get a garden store, botanical gardens or hybridized self. Trust nobody especially if say it cannot be done. That’s a challenge to disprove. Poor research or just plagerism is whatever you wish too call it, it was I believe entertaining. I’ve never taken any botany. Never offered when had opportunity. My immunity to major human killers may too die with me and few others who carry the protein coat. Other gifts, of evolution gotta explain function of allergies now, then find chemicals likely funeral or doctor visit meds that are money or life rico class organized crime crooked act. Cartels aren’t this bad as met in Puerto Arrista and Zipolite. Hope if read unlikely not offended as not my intent. Disclaimers verify all for self, host did also make proper disclaimers!

    • @acuddlyheadcrab
      @acuddlyheadcrab หลายเดือนก่อน +7

      first weird comment has been achieved congrats aryanpriviledge9651

    • @natzos6372
      @natzos6372 26 วันที่ผ่านมา

      Did you actually write this​@@aryanprivilege9651

    • @harmonic5107
      @harmonic5107 3 วันที่ผ่านมา

      ​@@aryanprivilege9651 seek help.

  • @FishareFriendsNotFood972
    @FishareFriendsNotFood972 หลายเดือนก่อน +148

    How this channel has broadened from 'what fruits taste like' to 'medical history' is fascinating and so, so exciting!

    • @Hsssssssssssssssssss
      @Hsssssssssssssssssss หลายเดือนก่อน +3

      He has envolved from a caveman mindlessly chewing on stuff to an alternative medicine doctor 😂

    • @willywonka7812
      @willywonka7812 หลายเดือนก่อน

      Sounds like a natural progression ​@@Hsssssssssssssssssss

    • @censusgary
      @censusgary หลายเดือนก่อน +2

      The channel has developed in a great way. It gets better and better.

  • @wyattblaine7066
    @wyattblaine7066 หลายเดือนก่อน +72

    22:22 if you take chalmugra with a grain of salt, you live 400 years

  • @benibear2995
    @benibear2995 หลายเดือนก่อน +92

    The quality of your episodes has been superb lately! Not just video and audio quality but the storytelling, going into depth on subjects, amazing work! I loved the old eating random fruits in a hotel room too, just love the depth and effort you put into them lately, and this one just pulled it up another notch! And such an important subject, done with respect!

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +24

      Glad to hear it!

  • @sproutingresilience4787
    @sproutingresilience4787 หลายเดือนก่อน +101

    With some research into chaulmugric acid, (there is actually quite a lack of current research on this molecule surprisingly. But what i found shows that it does have antibacterial properties just as you suspected, the authors theorize based on there finding that it inhibits the growth of new cells by disrupting cell membrane processes (Cabot MC, and Goucher 1981). Also it may have been able to help with neurological symptoms in some capacity as it can act as an activator of protein phosphatase 5 which if inhibited by disease can cause neurological symptoms. (Cher C, Tremblay MH, Barber JR, Chung No S, Zhang B, 2009)

    • @censusgary
      @censusgary หลายเดือนก่อน +4

      If it disrupts cell membranes and inhibits the growth of new cells, I wonder if it could be the basis for an anticancer drug.

    • @dingdonglong803
      @dingdonglong803 หลายเดือนก่อน +4

      It’s been used since ancient times, it can’t be for nothing. I believe there is something to the fruit that helps treat/cure it. I would hope there’s more research into the compounds of the fruit.

    • @cursedlight6606
      @cursedlight6606 หลายเดือนก่อน +1

      @@dingdonglong803 There are tons of plants which have been used since ancient times which we now know do absolutely nothing or worse, actually harm you, it really wouldn't be surprising that this fruit did nothing too.

    • @dingdonglong803
      @dingdonglong803 หลายเดือนก่อน

      @@cursedlight6606 what about some of the cases where some people were cured? Maybe somewhere along the way the Western method bastardized it and made it ineffective.
      He mentioned in the video they eventually narrowed it down to two chemicals in the seeds and they began only extracting those two compounds, what if that person who discovered those compounds were wrong and left something else behind.
      Or maybe it has properties to treat other skin maladies…who knows, but we shouldn’t quickly toss it out just yet, especially with modern technology that wasn’t available back when they did all these experiments, there’s still a lot that we don’t know…

    • @koushuu
      @koushuu หลายเดือนก่อน

      @@cursedlight6606 Indeed. Placebo effect is more often than not a very effective drug

  • @rachel4483
    @rachel4483 หลายเดือนก่อน +71

    The mycobacteria genus is one of my least favorite. I feel like across the biological world there's a mycobacterium for every species of animal that almost always terminally sickens and kills the organism and is impossible to kill within the living and it contaminates the environment for anywhere from years to forever. I'm so glad we've mostly moved past that point with humans. The world doesn't need a human version of Johnes disease, CRD, snuffles, fish TB, mycoplasma pneumonia, resistant abscesses or any of the other things I wish we didn't have to be aware of.

    • @censusgary
      @censusgary หลายเดือนก่อน +3

      Isn’t that “flesh rotting” organism also a mycobacteria species?

    • @seisage
      @seisage หลายเดือนก่อน

      Fun fact! Humans can contract fish TB (mycobacterium marinum). It's the only zoonotic disease from fish. Thankfully, it manifests much differently in humans than it does in fish. It's still bad news in humans, and treatment is lengthy and intensive, but at the very least, it's slow-growing tubercle lesions on the hands instead of whole-body wasting and death. Edit: it's also extremely rare in humans, so don't fret about sticking your hands in fish tanks. Still best to avoid doing so when you have open wounds though.

    • @MandrakeFernflower
      @MandrakeFernflower หลายเดือนก่อน

      ​@@censusgaryBuruli ulcer
      Also mycoplasma is different from mycobacterium

  • @LindaB651
    @LindaB651 หลายเดือนก่อน +22

    I'm old now, but I remember my Dad telling me about when he was in the Military Police before I was born, in the Philippines, just at the end of WW2. He said he'd sometimes pick up "lepers" that needed a ride, but they had to stay waaay back in the bed of the jeep, and/or truck, and be dropped off somewhere relatively private, so no one could see they'd been assisted. Dad would get somebody (a paid local person) to scrub down the vehicle at the end of the day. He wasn't particularly afraid, but he wasn't taking too many chances.
    I'm glad we can finally move beyond the mindset that disease equals unclean because, although hygiene and lifestyle choices can have a marked influence upon health, quite often we're at the mercy of happenstance!

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +10

      Very interesting! thanks for sharing. Do you know if that was that the Culion facility? I believe it was the largest lazzaretto in the world, one of the ones that had their own currency

    • @LindaB651
      @LindaB651 หลายเดือนก่อน +5

      @@WeirdExplorer Alas, I've no way of knowing. Dad didn't share a lot of his military experiences with us, and his untold stories passed with him in 99, never to be revealed.
      As for currency, my father said he'd pay the housemaid with food, cigarettes, and chocolate, but he never discussed actual monetary exchanges.

  • @JTMusicbox
    @JTMusicbox หลายเดือนก่อน +83

    Still watching but convinced that the claymation is the best part despite not having seen it all

    • @mleshoestar777
      @mleshoestar777 หลายเดือนก่อน +4

      & orange stop motion intro ☺

    • @hopegold883
      @hopegold883 หลายเดือนก่อน

      Def a high poont

  • @demonkiller479
    @demonkiller479 หลายเดือนก่อน +54

    I'm not finished yet, but I'm really really enjoying this longer more documentary style breakdown of a fruit and its history.
    I just finished the video and yeah this video was phenomenal and I hope we can get some more of these in the future.

  • @WeirdExplorer
    @WeirdExplorer  หลายเดือนก่อน +129

    I hope you enjoy my deep dive into the incredible history of this fruit.
    TONIGHT I will be doing a live stream to talk about some weird stuff that happened when I made this episode and also do a live Q&A about the episode and what's next on the channel.
    Tune in 7pm EST.

    • @kijanajenkins2546
      @kijanajenkins2546 หลายเดือนก่อน +4

      Great videos. 👍🏾

    • @sandrastreifel6452
      @sandrastreifel6452 หลายเดือนก่อน +4

      I love healthcare history!

    • @richardbidinger2577
      @richardbidinger2577 หลายเดือนก่อน +5

      You should do this more often.

    • @paulwright8378
      @paulwright8378 หลายเดือนก่อน +3

      That's midnight in the UK

    • @erzsebetkovacs2527
      @erzsebetkovacs2527 หลายเดือนก่อน +4

      Great video, enjoyed it despite its horrific subject matter. Just a note: as so often in medical history, a disease in the past may not be same disease in the present, even though both are called by the same name. What the Bible calls leprosy might have been (at least in some cases) non-contagious skin diseases, not true leprosy.

  • @pattheplanter
    @pattheplanter หลายเดือนก่อน +22

    History Unpeeled, delivered with zest, separating the pulp fiction, getting all the juicy facts, sowing the seeds of scientific curiosity and comes in bite-size segments.

  • @takforalt
    @takforalt หลายเดือนก่อน +13

    Since you referenced Hawaii several times. The leper colony on Molokai, known as Kalaupapa, was established in 1866 to isolate people with Hansen's disease (leprosy). Father Damien, a Catholic missionary, arrived in 1873 and improved living conditions until his death from the disease in 1889. Medical advances in the 1940s reduced the need for isolation, leading to better treatment and the eventual closure of the colony. Today, Kalaupapa is a National Historical Park managed by the National Park Service, preserving its history and educating the public.

    • @juliemcgugan1244
      @juliemcgugan1244 หลายเดือนก่อน +2

      Where I grew up, in Singapore, we also had an island that became a leper colony, called St John's Island. It was also used as isolation space for Cholera and Beri-Beri. Until people knew more about treating these diseases and stopped persecuting these poor people. Then, it served as a penal colony for drug offenders. Luckily, this was also stopped, although the death-penalty remains in-place, for certain drug offenses to this day, including importing drugs into the country with intent to sell (Which is only determined by amount.) So not all lessons have been learn, until this day, unfortunately.

    • @takforalt
      @takforalt หลายเดือนก่อน

      @@juliemcgugan1244 That was very interesting. By the way, I live in Phuket, Thailand. There are no leper colonies here that I know of, but I have seen those unfortunate enough to have the disease.

    • @juliemcgugan1244
      @juliemcgugan1244 หลายเดือนก่อน

      @@takforalt I've been to Phuket. Thailand is a lovely country and the people are so kind and welcoming.

  • @Hortifox_the_gardener
    @Hortifox_the_gardener หลายเดือนก่อน +29

    Wow a one hour Weird Explorer video? What a treat! Awesome. Would love more of that format. Thanks so much for researching it.

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +9

      More to come!

    • @applegal3058
      @applegal3058 หลายเดือนก่อน

      So excited to see more like this video...deed dive of historical uses of plants and fruits!

    • @keegsmarshall6610
      @keegsmarshall6610 หลายเดือนก่อน

      I would suggest you create teaser videos because a lot of people are put off by long form videos.​@@WeirdExplorer

  • @sharendonnelly7770
    @sharendonnelly7770 หลายเดือนก่อน +12

    Jared, i think this was your best video ever. You took a fruit, found the correlation between a disease and its effect, researched it, and gave us a very detailed history and application. Wow! Then reality hits, Awesome deep dive! Really enjoyed this, (always enjoy your videos!), and appreciated very much all the hard work you put into this. Thank you!

  • @nickc3657
    @nickc3657 หลายเดือนก่อน +7

    Bonus fun fact! Dapsone is still saving people from “monstrous” skin. It’s used for spider bite infections, but also for acne! It helped clear my face almost completely. Some people will regard severe acne like leprosy, so Dr. Fromm you kind of succeeded!

    • @soniarose1983
      @soniarose1983 3 วันที่ผ่านมา

      Wow. My son needs some of this, they’re turning into deep scars that look like burn scars on his back and face

    • @nickc3657
      @nickc3657 2 วันที่ผ่านมา

      @@soniarose1983 I’m so sorry to hear that :( my dermatologist is who prescribed it after other antibiotics stopped working. I think it’s a matter of just trying different stuff until you find the combination that works. For me it’s a prescription retinoid, dapsone, and sports wash (because I sweat a lot.) I 100% recommend a dermatologist, and if you feel like they’re not helping, try another (I did so twice).

  • @lindasilva666
    @lindasilva666 หลายเดือนก่อน +5

    As someone with a fascination for infectious diseases and ethnobotany, I quite enjoyed this episode. This takes me back to my first job in Thailand in the early 90s when it was not uncommon to see beggars with advanced leprosy panhandling on the streets of Bankok's shopping districts. Cheap though multi-drug treatment might have been, it was not until WHO started providing free treatment in the mid-90s that the rates really started dropping in the more remote corners of the world.

  • @wisecoconut5
    @wisecoconut5 หลายเดือนก่อน +12

    In Kansas, our department of wildlife regularly tests the local armadillo population for Leprosy. So far, they say our armored pigs are healthy. Still, don't eat road kill folks! Great video. I loved the claymatiom and illustrated story telling.

    • @loris3595
      @loris3595 17 วันที่ผ่านมา

      Armadillos do not get leprosy. They survive being hit by cars sometimes and are all skinned up.

    • @wisecoconut5
      @wisecoconut5 3 วันที่ผ่านมา +1

      @loris3595 Armadillos do, in fact, carry leprosy. And, they do, in fact , fail to survive being hit by cars. Moreover, they have a sense of humor and laugh about it all.

  • @ns_abel3460
    @ns_abel3460 หลายเดือนก่อน +14

    I almost clicked off the video when I saw the time but ended up watching the whole video in one go.
    Really interesting

  • @Steph-zo5zk
    @Steph-zo5zk หลายเดือนก่อน +14

    I this is my favourite video of yours I've seen so far, the history of obscure fruits and their uses is so cool. Lovely to take the opportunity to draw attention to Alice Ball's contributions as well, she sounds like a brilliant mind, so sad she died young I'm sure she would have been a gift to medical research

  • @sethlievense8371
    @sethlievense8371 หลายเดือนก่อน +21

    That claymotion was amazing 😍

  • @noahrouleau9598
    @noahrouleau9598 หลายเดือนก่อน +14

    This long-form heavily-researched content is excellent. Loved seeing the journey from brashly trying an unknown fruit to learning all about it. I think lots of us will spread awareness as you requested, but it'll be a balancing act trying to share unsolicited fun facts about leprosy, without becoming a [...] social [...] persona non grata.

  • @Eskermo
    @Eskermo หลายเดือนก่อน +2

    Thank you for the extensive video essay on chaulmoogra and its connection to leprosy! I hope that this and John Green's videos on tuberculosis start a trend on TH-camrs raising awareness for treatable illnesses so that help reaches the places that need it the most but have the least access.

  • @capnstewy55
    @capnstewy55 หลายเดือนก่อน +7

    A leprosy documentary from my favorite fruitologist!?! Of course I'll watch the whole thing. Oscar! Oscar!

  • @patricioiasielski8816
    @patricioiasielski8816 หลายเดือนก่อน +6

    Great one. I hope you make more of these episodes, would love to see one about Quinine or Pyrethrins

  • @Eveseptir
    @Eveseptir หลายเดือนก่อน +6

    Beyond the well earned praise you already got for this, I gotta say I really appreciate the little animation you made about the king in the forest. Seeing that little dude walking in the woods put a smile on my face.

  • @hatface240
    @hatface240 หลายเดือนก่อน +15

    Love the way you did this video, and its great that you are raising awareness about the treatment of people with leprosy in the modern day.

  • @jordov9398
    @jordov9398 หลายเดือนก่อน +3

    I swear, you’re one of the coolest people to have ever lived.

  • @Indianny
    @Indianny หลายเดือนก่อน +4

    I love the long format video @WeirdExplorer. I don’t know what exactly it is, but your style has strong PBS vibes and I love it.

  • @kyrab7914
    @kyrab7914 หลายเดือนก่อน +2

    This has such arthouse film vibes. Much credit for the claymation and just entire opening. Also the history, and stories you tracked down. All the research. V well done

  • @dakota3347
    @dakota3347 หลายเดือนก่อน +11

    Whoa! Ngl, i think this is one of your best videos!

  • @darriendastar3941
    @darriendastar3941 หลายเดือนก่อน +5

    This was great. It's probably the most interesting (and entertaining) thing I'll see on TH-cam this year.
    Thank you for taking the time and effort to make this video.
    As a result of your video, I've made a donation to the charity Lepra (mentioning you and this video) that's aimed at eradicating the disease. So, because you made this video, I hope at least two people will be cured. 🙂

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +3

      That's wonderful. thanks so much

  • @middlemuse
    @middlemuse หลายเดือนก่อน +5

    This video is so impressive and educational! I really hope it does well, I’m going to share it around with my friends.

  • @Locut0s
    @Locut0s หลายเดือนก่อน +3

    I look forward to every video you make! But these long form historical videos are really amazing! Fantastic work!

  • @tktyga77
    @tktyga77 หลายเดือนก่อน +3

    Came in for the food uses of the fruit, left with the medical help is one fitting way to describe the video

  • @davids9027
    @davids9027 หลายเดือนก่อน +2

    Thank you for attempting to inform people with correct information about leprosy. the superstitious belief that "if I don't understand it, it must be a curse (miracle, if it benefits me.) Unfortunately I have met people who insist on learning about the world by reading nonscientific religious tracts rather than studying scientific studies. Kudos for Miss Ball's research to improve treatments of leprosy.

  • @Gearmond
    @Gearmond หลายเดือนก่อน +1

    having followed you since you've had 4 figure followers, this is your best video on so many levels and your sincerity about every aspect of this fruit and its history is wonderful and you do good diligence with this video for the sake of others in a way that feels very genuine

  • @Allenar4
    @Allenar4 หลายเดือนก่อน +1

    I hope this video does well with the algo because this is one of my favorite videos on the platform (not just you) and I would love for this format to be profitable so we can get more.
    The deep research the disclosure of your expertise (or non expertise) on the subject, the measured conclusion based on the evidence. Chefs kiss. Basically following scientific principles in a format that exaggeration is rewarded instead.

  • @fokkerd3red618
    @fokkerd3red618 หลายเดือนก่อน

    You deserved to be awarded for this presentation. I learned more about Leprosy from your program than I've ever known. The hours of research you must spent on this subject is very impressive. Well done.

  • @arnaldorentes5371
    @arnaldorentes5371 หลายเดือนก่อน +5

    Dear Jared, I'm not sure how long I've been following your work, but it's been a few years. And you GREW, as this episode demonstrates. CONGRATULATIONS!
    I contribute as much as I can at the moment. Brazil has a terrible history with leprosy. Doctors created a secret society that kidnapped sick people from their families and took them to distant leper colonies. There's so much more and it's all very sad. Anyway.
    The curiosity is that there is a tree native to our Atlantic Forest that was called "brazilian chaulmoogra" and was also used against leprosy. It is the "sapucainha" (or little sapucaia), Carpotreche brasiliensis. The botanical family is the same, Achariaceae. Also woody, the fruit is similar in size, but is all ridged, vaguely reminiscent of an old granade. Likewise, the medicine is the oil from the seeds. Its medicinal history was brief, as it lost its position in the 1920s to synthetic sulfones, primitive but effective antibiotics. The fact that patients were not isolated was decisive for the early retirement of the "Brazilian chaulmoogra". If you are interested, you will find more information in articles from the Oswaldo Cruz Foundation (FIOCRUZ), in Rio de Janeiro. That was it and once again, congratulations on all your work and for this precious video!

  • @diplenski
    @diplenski หลายเดือนก่อน +2

    Not surprised it’s Florida tbh. I know they’re low hanging fruit, but they are also known to mess with wildlife against better judgement

  • @luisledesma586
    @luisledesma586 หลายเดือนก่อน +1

    I have watch your work for a couple of years now and enjoy almost everything you have presented; this one is on a whole different level, a very fine piece of investigative journalism, thank you so much.

  • @acccardone7679
    @acccardone7679 หลายเดือนก่อน +1

    Thank you for this fascinating deep dive into the history of this fruit, and of Leprosy! As a hobbiest in both history and the history and modern uses of herbology, I found this video fascinating. In addition, the way you presented this information had me listening with enthusiasm at every point of this video. Great job!

  • @isaacthedestroyerofstuped7676
    @isaacthedestroyerofstuped7676 หลายเดือนก่อน +1

    Awesome video!!! I would LOVE to see more of this kind of content! However, I absolutely anticipate these being few and far between with the sheer amount of effort you put into this.

  • @PeterTea
    @PeterTea หลายเดือนก่อน +1

    Wow! Thank you for your hard work in bringing us this story. The potential eradication of leprosy reminds me of another eradication effort, polio. Since polio is only found in humans, when it is eventually eradicated it will cease to be a public health problem. And right now, what used to be a public scourge, is only found in 3 countries with dwindling numbers of infections.

  • @JHaven-lg7lj
    @JHaven-lg7lj 16 วันที่ผ่านมา

    I watched your non-dairy milk competition compilation last month and thoroughly enjoyed it. And now I’m delighted to see that you’re dabbling in storytelling again, with the wonderful claymation!

  • @MikePuorro
    @MikePuorro หลายเดือนก่อน

    I've been watching weird fruit explorer from the beginning. It's been amazing to our protagonist go from hunting fruits from local stores, to traveling the world, and now doing some serious journalism, the likes of which rivals PBS and National Geographic.

  • @Varudox
    @Varudox หลายเดือนก่อน

    I absolutely adore this style of video, you’re a very good storyteller! I’ve also noticed your video and audio quality have been improving a lot lately, keep up the great work! i’m hoping this type of content can be sprinkled into your uploads between the typical reviews and such, fascinating!

  • @maccakhan1628
    @maccakhan1628 หลายเดือนก่อน +1

    This is quite possibly the best video you have released on this channel.
    Great job!

  • @TheGreatDrAsian
    @TheGreatDrAsian หลายเดือนก่อน +1

    Super awesome episode man!!
    Very well researched and written.
    You did a brilliant job of celebrating history, telling the story, and staying real.
    I love your camerawork and editing too.
    Fantastic work bro. 10/10

  • @mudgetheexpendable
    @mudgetheexpendable หลายเดือนก่อน +2

    Yay science! All of it is science-driven, and the conclusion not including the beginning's efforts shows that science as a framework for thought and action WORKS!

  • @MUtley-rf8vg
    @MUtley-rf8vg หลายเดือนก่อน +3

    It took me a couple days worth of freetime to swallow this bastard but it was worth it.
    Just want to say thanks for the clear amount of hard work that has gone into this video. Have always enjoyed your longer format videos. Appreciate your skills as a documentarian, your storytelling ability, and information presented without pretense, including healthy amounts of skepticism, humor, and absolutely terrible lo-fi effects. :)

  • @sdfkjgh
    @sdfkjgh หลายเดือนก่อน +3

    6:40 Decades ago, I came up with the idea for a snow leper. It's known for the bits of it that keep dropping off and melting, and by its cries of "UNCLEAN! UNCLEAN! COLD AND UNCLEAN!"

  • @elliephants7047
    @elliephants7047 หลายเดือนก่อน

    I love your longer-form videos! I know that they sometimes don't do as well as you'd hope, and I'm more than happy to watch anything you give us, but I love learning!!! This is really interesting history as well, something I've never learnt about. Thank you!!

  • @ducky169
    @ducky169 หลายเดือนก่อน

    Thanks for producing such a great historical poignant and informative documentary
    Love the whole deep dive into such a seemingly insignificant fruit.
    You clearly run your channel with care and love (not just pumping out money grabbing effortless videos) ❤
    Your a legend mate and hope you never stop

  • @aidanjohnson3169
    @aidanjohnson3169 หลายเดือนก่อน

    Probably the best video you’ve put out yet, really well done

  • @shadownite3378
    @shadownite3378 หลายเดือนก่อน

    I always appreciate how well researched and honest your work is. You don't try to misrepresent or misconstrue anything. This is definitely one of my favorite videos from you by far.

  • @ZeroToMidnight
    @ZeroToMidnight หลายเดือนก่อน

    Such fantastic work! This is probably the best video I’ve seen on YT this week!

  • @Amy-Bo-Bamy
    @Amy-Bo-Bamy หลายเดือนก่อน +1

    Wow, so eye opening. My heart goes out to all the poor helpless souls whose lives have been broken by this disease. 😢

  • @LisaKini
    @LisaKini หลายเดือนก่อน +2

    These keep getting better!!

  • @davidcatanach2620
    @davidcatanach2620 หลายเดือนก่อน

    Great episode! Love the deep dive and greatly respect your rational approach to the topic.

  • @Castaway67
    @Castaway67 หลายเดือนก่อน

    Haven't come across you're channel before. Happy to say you scratched my itch for in depth history of something I knew absolutely nothing about. Well done.

  • @Thebritcoll
    @Thebritcoll 16 วันที่ผ่านมา

    Damn I commented on another video that I hadn’t seen you in a while… I really like this turn in content towards history, research, and script. This video hit hard while also keeping in the channel spirit. I’ll share idk how to help that well... Good content do what your heart says!

  • @jamestboehm6450
    @jamestboehm6450 หลายเดือนก่อน +4

    A truly fascinating deviation from your normal videos. I learned things that i didn't know and rearranged thoughs on misconceptions. Thanks bud, this was well worth the watch time.

  • @dreckken
    @dreckken หลายเดือนก่อน

    This was awesome! Great video Jared!

  • @BozackZodiack
    @BozackZodiack หลายเดือนก่อน

    This was SUPER interesting! I love how you string together the history, the controversies, the fruit, the exploring, and the characters - you are a great story teller!

  • @gatomaru
    @gatomaru หลายเดือนก่อน

    omg you did stop motion again! i've been asking since the covid video! i'm so happy, it was great!

  • @kirktown2046
    @kirktown2046 หลายเดือนก่อน

    Hey this is getting pretty good, you seem to be stepping up your game and productions! Keep it up mate, loving this channel since Destin plugged you on SED.

  • @prehistoricpleb
    @prehistoricpleb หลายเดือนก่อน

    This is your best video to date. Well presented and researched. I love history.

  • @fakkelplemp
    @fakkelplemp หลายเดือนก่อน +2

    thanks for the very complete story,
    I hoped you would mention the sunk cost fallacy when pointing out why they kept researching a placebo

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน +1

      You're right. it's a great example of that

  • @interestings7866
    @interestings7866 หลายเดือนก่อน

    Love these longer essay style videos from you!

  • @GarysBBQSupplies
    @GarysBBQSupplies หลายเดือนก่อน

    Very well done episode. I am very impressed with the depth of research you did on this one. Thank you for sharing.

  • @Ucceah
    @Ucceah หลายเดือนก่อน

    OP just transcended several power levels!
    once i subscribed for amusing vids of picking weird ass fruits with a drunken local at a road side, and failing to make them edible. and it sure was fun to wach!
    but this is S-TIER content, with immaculate research and editing, and not s second of my time wasted.
    i am SO looking forward to more ethno/histo-biology lessons of this epic calibre.

  • @canadiansmarties
    @canadiansmarties หลายเดือนก่อน

    Beautifully edited video. Love the animation. Very excited to see the channel continue to grow ❤️

  • @sinisterthoughts2896
    @sinisterthoughts2896 หลายเดือนก่อน

    Phenomenal video! Thank you for putting in all that hard work to ahare this with us.

  • @michaelperrone3867
    @michaelperrone3867 หลายเดือนก่อน +1

    Amazing research as always!

  • @bullchargersc
    @bullchargersc หลายเดือนก่อน

    Love me some food history, and your animations are always a joy to watch.

  • @MermaidMakes
    @MermaidMakes หลายเดือนก่อน

    LOVING this new format!! The history of fruit is fascinating, even for the most seemingly mundane fruits. You will have plenty of material to work with for this series!

  • @objective_psychology
    @objective_psychology หลายเดือนก่อน +1

    I absolutely LOVE the new series! Keep up the (un)peeling!

  • @animeleepocket7984
    @animeleepocket7984 หลายเดือนก่อน +1

    Since 2020 I've gone back and watched EVERY. SINGLE. VIDEO. As well as EVERY. SINGLE. PATREON. EXCLUSIVE. I proudly wear my durian shirt! This is probably my favourite video of yours I've had the pleasure of watching, I was attached to the screen the entire way through. Your diligence is astounding as I'm certain the vagaries of traditional medicine journals and sentiments lost in translation proves research to be frustrating and teeming with dead ends. I really hope this pops off and is recommended like crazy on this site. Amazing.

  • @kensmith5694
    @kensmith5694 หลายเดือนก่อน +3

    An interesting thought is that they may have missed something. They focused on the oil of the fruit's seeds. What it the real effect is from the pulp of the fruit or something else from the seeds. Could it be that there is something in there that in general improves diseases like an inti-inflammatory or pain killer.

    • @JP_Names
      @JP_Names หลายเดือนก่อน

      Yeah, and it probably wasn't a miracle medicine, and especially when they went back to retest it later on down the line, they likely had better alternatives for whatever medical effects it was doing. Sort of like comparing an ice bath to ibuprofen for handling a fever

  • @walterduncan1778
    @walterduncan1778 หลายเดือนก่อน +1

    You're on your way to becoming the Joe Scott of fruit. Great episode!

  • @LMF1716
    @LMF1716 หลายเดือนก่อน

    This was an incredible video to watch, I had no idea about most of this story but it was very interesting to listen to!

  • @juanrojas2595
    @juanrojas2595 17 วันที่ผ่านมา

    This is the greatest video you've made! Just by the way you talk in this video, I can tell it might have been a little difficult to research a topic this dark, but I think us viewers all very much appreciate your presentation of a past forgotten by many around the world.

  • @laureeeent
    @laureeeent หลายเดือนก่อน

    great episode mr jared!

  • @acelticmiscellany
    @acelticmiscellany หลายเดือนก่อน

    That was great, I would enjoy more of your content like this, well done

  • @randomname7321
    @randomname7321 หลายเดือนก่อน +1

    It was so good it gave me chills. Please do more videos like this. Also I really enjoyed the livestream after party! As long ad you are comfortable maybe try doing those more!

  • @Shizukanexen
    @Shizukanexen หลายเดือนก่อน

    Oh wow! This was a fantastic history video! Amazing work!

  • @aza8800
    @aza8800 หลายเดือนก่อน

    I love seeing the shots of your groups! Hopefully I can go on one someday. Great, informative video!

  • @sum_rye_hash_321
    @sum_rye_hash_321 หลายเดือนก่อน

    The Coco de Mer series is what really got me subbed to your channel, I thoroughly enjoyed this deep dive into Chaulmoogra and subsequently Hanson's Disease (Mmm bop disease? lol) I also liked the Iceland Banana Saga, can't wait to see what random deep dive/extended docuseries or whatever comes next!

  • @MrJBLH
    @MrJBLH หลายเดือนก่อน

    Fascinating video, really enjoyed watching it all and learning more as usual.

  • @falcolf
    @falcolf หลายเดือนก่อน

    Awesome little documentary, I'd never heard of this fruit and this was an epic history of leprosy/Hansen's Disease! ❤ Epic hard work on this!!

  • @alexis-zt6xd
    @alexis-zt6xd หลายเดือนก่อน

    I absolutely love your full length videos. Great work. This was fascinating!

    • @WeirdExplorer
      @WeirdExplorer  หลายเดือนก่อน

      Awesome, thank you!

  • @PhosphorAlchemist
    @PhosphorAlchemist หลายเดือนก่อน

    Love the mix of classic short tasting videos and these long-form documentaries.
    I was glad to hear Alice Ball come up. She was among the first women to be independent professional chemists at all (as opposed to "lab assistants" whose ideas had to be carried by a man), and I'm glad she's getting more name recognition. As you say, the thing she did was still big, enabling a tolerable dosage form and commercialization.

  • @Ariel-ns4yr
    @Ariel-ns4yr หลายเดือนก่อน

    So very interesting! Thank you for doing so much historical research and sharing. Really enjoyed watching.

  • @WeirdOneOz
    @WeirdOneOz หลายเดือนก่อน

    Thanks for sharing the story of the fruit and about its history in our lives. Well researched and presented.

  • @ferretyluv
    @ferretyluv หลายเดือนก่อน +9

    Just say “leper.” And leper colony is different from a leprosarium. The latter is just a building. The former is an isolated settlement, sometimes an island. Hence the term colony.
    Yeah India still has a problem with leprosy. You can avoid leprosy in America by not touching armadillos.

    • @SeekingTheLoveThatGodMeans7648
      @SeekingTheLoveThatGodMeans7648 หลายเดือนก่อน +1

      Could armadillos be given medication to cut down armadillo leprosy?

    • @ferretyluv
      @ferretyluv หลายเดือนก่อน +1

      @@SeekingTheLoveThatGodMeans7648 not really. It takes long term treatment, it’s not like a rabies shot. It’d be more likely to create drug resistant leprosy than help. Cases are in the single digits so it’s not exactly a priority.

    • @JP_Names
      @JP_Names หลายเดือนก่อน

      ​@@ferretyluvand it's only one of the like two major varieties of armadillos, the other one doesn't really carry it

    • @ferretyluv
      @ferretyluv หลายเดือนก่อน

      @@JP_Names Nine banded armadillos are the most common and they carry leprosy. They’re the kind that’s often roadkill.

    • @hoperules8874
      @hoperules8874 หลายเดือนก่อน

      idk without checking but think it is part of their natural biology, like the plague is native to prarie dogs

  • @Noctiluca333
    @Noctiluca333 หลายเดือนก่อน

    This is was absolutely fascinating. By far one of the best historical accounts of a fruit I have ever watched!

  • @balancehd5657
    @balancehd5657 หลายเดือนก่อน

    Absolutely wonderful, I LOVE long format videos like these. I'd give it a bit of time, it'll find the right crowd shortly

  • @lfuboi
    @lfuboi หลายเดือนก่อน

    Great episode!