I Grew Real Spider Silk Using Yeast

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  • เผยแพร่เมื่อ 22 ธ.ค. 2024

ความคิดเห็น • 6K

  • @whatdamath
    @whatdamath 4 ปีที่แล้ว +2338

    dude...

  • @no_name4485
    @no_name4485 3 ปีที่แล้ว +2596

    mad scientists in movies: I will take over the world
    mad scientists in real life: I will make beer out of spiders

    • @greenaum
      @greenaum 3 ปีที่แล้ว +99

      Technically making spiders out of beer.

    • @tartanhandbag
      @tartanhandbag 3 ปีที่แล้ว +49

      @@greenaum technically making something not very beer-like out of a yeast variant with spider DNA spliced into it

    • @Butter-Milk
      @Butter-Milk 3 ปีที่แล้ว +15

      We have more realistic goals, then?

    • @morro570
      @morro570 3 ปีที่แล้ว +9

      @@Butter-Milk who’s we you aren’t a mad scientist

    • @what908
      @what908 3 ปีที่แล้ว +3

      mado scientisto in animes: El Psy Congroo.

  • @user-N20
    @user-N20 4 ปีที่แล้ว +10175

    No wonder Tony Stark looked so impressed when Peter said he manufactured his webbing all by himself.

  • @zebbofrags494
    @zebbofrags494 ปีที่แล้ว +197

    Sad to see this experiment hasn’t been taken any further in 3 years. This genuinely made me feel interested in science for the first time in my short 20 year life.

    • @thethoughtemporium
      @thethoughtemporium  ปีที่แล้ว +234

      It's being worked on, but we're trying to commercialize it so can't share updates yet

    • @_dylansaeed
      @_dylansaeed 11 หลายเดือนก่อน +34

      @@thethoughtemporiumthanks, I was wondering why it wasn’t being continued

    • @sasukekun1997
      @sasukekun1997 9 หลายเดือนก่อน +28

      This had made so damn happy. I thought this project was long forgotten

    • @Delapadation
      @Delapadation 9 หลายเดือนก่อน +15

      ​​@@thethoughtemporiumI would think that this would get funding fairly easily due to how strong spider silk is and the amazing utility we could get out of growable high strength building materials, and something I just thought of while watching the video explaining the structure, spider silk is a fabricy version of reinforced concrete.

    • @Yogaismehh
      @Yogaismehh 8 หลายเดือนก่อน +3

      @@thethoughtemporiumlike a suburban superhero???

  • @jacob2802
    @jacob2802 4 ปีที่แล้ว +2625

    Dude, I cant believe you're making this technology open source. I've been reading about the possibilities of harnessing spider silk since I was a dork in middle school, and remember thinking the guys making the spider goats were cool as hell. I really hope you manage to extract and polymerize silk from this.

    • @aserta
      @aserta 4 ปีที่แล้ว +318

      Because he's one of the good guys, not subverting science for the highest bidder. He's one of those scientists that need crowdfunding the most, to keep him free of the likes of bigCorpo who'd put a life patent latch on it and shut it for good.

    • @davidbergmann8948
      @davidbergmann8948 4 ปีที่แล้ว +13

      Haha yeah it's awesome, right? 🍄

    • @rihardsrozans6920
      @rihardsrozans6920 4 ปีที่แล้ว +51

      Right? I remember watching Ripley's believe it or not as a child and one of the guys featured there had made a really durable, strong suit out of bunch of materials including spider silk he milked out of actual spiders and since then I wondered about the possibilities of creating some super hero costume out of spider silk. It's truly wonderful that people are coming together to make education easily accesible and likely creating future scientists.

    • @garethbaus5471
      @garethbaus5471 4 ปีที่แล้ว +1

      Same here.

    • @suhanrahaman4342
      @suhanrahaman4342 4 ปีที่แล้ว +13

      Even though spider sill is a real good material it also get most of its strength through how the spider twists the silk together

  • @cg2229
    @cg2229 4 ปีที่แล้ว +5943

    me laying in bed eating cheetos: ah yes of course biomineralization peptides

    • @ghostlydude6478
      @ghostlydude6478 4 ปีที่แล้ว +192

      This is basically me trying to understand how kars survived falling into lava, but with *Spiders*

    • @aog1747
      @aog1747 4 ปีที่แล้ว +19

      Hell yea😂😂😂

    • @xephyre6955
      @xephyre6955 4 ปีที่แล้ว +56

      I dont even understand algebra let alone this. But the idea is interesting enough for me.

    • @v1298
      @v1298 4 ปีที่แล้ว +39

      I saw a post online about the iron snail a couple of days ago, so I'm basically an expert

    • @saki1333
      @saki1333 4 ปีที่แล้ว +8

      @@v1298 yes xD

  • @Nighthawkinlight
    @Nighthawkinlight 4 ปีที่แล้ว +2567

    Instant thumbs up. Been waiting for this one.

    • @-NGC-6302-
      @-NGC-6302- 4 ปีที่แล้ว +2

      Me too. Great videos from the both of you.

    • @jonapple2325
      @jonapple2325 4 ปีที่แล้ว +1

      Are you okay

    • @JKTCGMV13
      @JKTCGMV13 4 ปีที่แล้ว +4

      This comment prompted me to give the video an instant thumbs up

    • @PakleniVuk
      @PakleniVuk 4 ปีที่แล้ว +2

      I will combine Yeast and Starlite and rule the World!

    • @stiepanholkien605
      @stiepanholkien605 4 ปีที่แล้ว

      Now he just needs little wrist siphons.

  • @joelswartzentruber9561
    @joelswartzentruber9561 3 ปีที่แล้ว +99

    Instead of wet spinning, try electrospinning. It should give you aligned fibers instead of randomly oriented ones from wet spinning. You should be able to cut a section and twist the web fibers into actual thread that are theoretically aligned so you get better load sharing on each fiber.

  • @davieuacho
    @davieuacho 4 ปีที่แล้ว +757

    Me, not understanding anything but still enjoying it none the less: "Ah, shit, they can't print repetitive sequences, what a bummer dude"

    • @evangrimm1702
      @evangrimm1702 4 ปีที่แล้ว +9

      😭

    • @hardanalljr.3138
      @hardanalljr.3138 4 ปีที่แล้ว +14

      Yup I'm a total Chad ,don't understand shit but it's cool

    • @liviawong6928
      @liviawong6928 4 ปีที่แล้ว +1

      @@hardanalljr.3138 Are you build as a Chad as well? Cause, cool.

  • @MagnusDangerMagnus
    @MagnusDangerMagnus 4 ปีที่แล้ว +541

    30:15 I love that I live in the future. The idea that I share the world with a TH-cam-vectored, open-source, melt-printable, github-published bio-kevlar makes me happier as an adult than ice-cream did as a child. Thank you.

    • @makarismaileadnan
      @makarismaileadnan 4 ปีที่แล้ว +19

      I really don't get what you're saying, but I'm happy that someone's happy in this world

    • @gavart4509
      @gavart4509 4 ปีที่แล้ว +30

      Makar Ismaile Adnan
      He’s happy that the creator of this video is so transparent with his process and so willing to share his results. Plus, the fact that this content is distributed for free.

    • @pacificxplorer
      @pacificxplorer 4 ปีที่แล้ว +1

      This is really “the future” it’s the transitional period between the past and the future. Right now everything cutting edge is being discovered and all these cool products will most likely be widely available by the time we’re all dead or really old.

    • @samuelr.6046
      @samuelr.6046 3 ปีที่แล้ว +5

      Is it just me or is it crazy that they can Patten certain animal genes, that's absolutely some dystopian stuff right there.

  • @AppliedScience
    @AppliedScience 4 ปีที่แล้ว +5916

    Wow, what an incredible project! Your dedication and perseverance is an inspiration!

    • @thethoughtemporium
      @thethoughtemporium  4 ปีที่แล้ว +479

      Thank you so much! Once I've got some fibers made, I'd be happy to send them over for you to play around with if you'd like

    • @KnowBigDeal
      @KnowBigDeal 4 ปีที่แล้ว +121

      Here's an idea: Electron Microscopy videos of all the mineralised silks!

    • @simonRTJ
      @simonRTJ 4 ปีที่แล้ว +51

      @@thethoughtemporium Maybe Ben could X-ray diffract image them, or run them through a mass-spec, or the Electron mic, or ALL THREE! amazing work, there should be a "TH-cam science medal" or something.

    • @MrEtronic
      @MrEtronic 4 ปีที่แล้ว +26

      i think we are on the cusp of a revolution ... who needs elsevier , springer or iEEE these dudes together with a couple other sci-tubers are doing more cutting edge research than many well funded snob colleges.

    • @Srfingfreak
      @Srfingfreak 4 ปีที่แล้ว +34

      @@thethoughtemporium Growing fibers is cool - But I would reccoment that you try mixing some into a Kombucha brew and make a SCOBY - you'll get nanocellulose tied to fibroin... it might be revolutionarily strong. Use weak/white tea if possible, and you can actually just use mineral supplements in sugar water for a "cleaner" SCOBY.
      Also, that way, the yeast/bacteria make the sheet for you, and you don't have to worry about the fiber weaving process.

  • @sparking023
    @sparking023 ปีที่แล้ว +247

    I have absolutely zero biochemistry background, but I somehow feel like I understood most of what you explained in this here video. Amazing work, and as a Spider-Man fan, I'm eager to know more about the possibilities of IRL webshooters

    • @Noflippingwaydude
      @Noflippingwaydude ปีที่แล้ว +2

      Don’t worry once I have money I’ll make them

    • @the_undead
      @the_undead 11 หลายเดือนก่อน +4

      This part you probably already knew, but using IRL web shooters with absolutely be one of the most dangerous things you've ever done or did anyone could realistically ever do, but spider silk binded with carbon nano tubes. Could absolutely if made correctly hold the weight of multiple humans, I don't think you're doing Oh that the web shooter could do in a little canister. That's the size of your pinky but in especially designed flat pack tank that goes over your stomach, now we're talking.
      Because of how easy it would be to vary the properties of the silk when you produce it, depending on which particular strand of genes you use, everything you see Spider-Man doing with webs would be at least theoretically possible to do with at least a version of what is demonstrated in this video

  • @jadegreenleaf781
    @jadegreenleaf781 4 ปีที่แล้ว +782

    Arachnologists for decades: "If only we could produce spider silk"
    Thought Emporium: "hold my spider beer."

    • @TheWretchedOwl
      @TheWretchedOwl 4 ปีที่แล้ว +40

      Now I want a “hold my spider beer” shirt.

    • @omniscientbarebones
      @omniscientbarebones 4 ปีที่แล้ว +16

      Hold my Southern Black-Widow in Ethanol*

    • @ultrachad289
      @ultrachad289 4 ปีที่แล้ว +2

      O-O WHAT THE FUCK

    • @alba2162
      @alba2162 4 ปีที่แล้ว +5

      I wonder what spider beer taste like

    • @trajectoryunown
      @trajectoryunown 4 ปีที่แล้ว +15

      Spider Cider - Made with real spiders

  • @lukasd.4389
    @lukasd.4389 4 ปีที่แล้ว +1935

    "I've become quite competent at designing dna from scratch"
    Why does this sound so menacing.
    But dude, youre awesome

    • @0Clewi0
      @0Clewi0 3 ปีที่แล้ว +15

      because of prions

    • @hunterbakko9306
      @hunterbakko9306 3 ปีที่แล้ว +46

      I mean he's kinda playing God so yes it is menacing

    • @adventurer3288
      @adventurer3288 3 ปีที่แล้ว +4

      You WHAT

    • @superchinmayplays
      @superchinmayplays 3 ปีที่แล้ว +18

      i can now become spiderman

    • @wobblewokgaming655
      @wobblewokgaming655 3 ปีที่แล้ว +11

      *He's becoming a Spider-Man villain*

  • @Shotgun_Gospel
    @Shotgun_Gospel 4 ปีที่แล้ว +5627

    Guy who invented penicillin: "Patent? That's absurd. You wouldn't patent the sun, would you?"
    Biotech firms: "Spider silk? Oh that was us, we invented that. Ours".

    • @sontapaa11jokulainen94
      @sontapaa11jokulainen94 3 ปีที่แล้ว +877

      Capitalism go brrrrr

    • @Hoshimaru57
      @Hoshimaru57 3 ปีที่แล้ว +734

      If someone could patent the sun they would

    • @nucleartoaster01
      @nucleartoaster01 3 ปีที่แล้ว +296

      Let's not encourage them

    • @nzoomed
      @nzoomed 3 ปีที่แล้ว +206

      @@Hoshimaru57 its called nuclear fusion!

    • @nzoomed
      @nzoomed 3 ปีที่แล้ว +371

      Can someone explain how anyone could hold a patent to a gene found in spiders to begin with?

  • @VirtualGobllim47
    @VirtualGobllim47 8 หลายเดือนก่อน +111

    "It's [spiders] silk gene wasn't protected by any patents" you guys realize as well how nightmarish is this sentence?

    • @magicsasafras3414
      @magicsasafras3414 4 หลายเดือนก่อน +1

      Yup

    • @carinhadoscomentarios4325
      @carinhadoscomentarios4325 4 หลายเดือนก่อน

      Why?

    • @cooldud7071
      @cooldud7071 4 หลายเดือนก่อน +21

      @@carinhadoscomentarios4325 nobody should own the right to naturally-occurring sequences of chemicals

    • @mikoajciemiega8018
      @mikoajciemiega8018 3 หลายเดือนก่อน +5

      ​@@cooldud7071 big corpo preparing to sue every spider on earth

    • @bearox8302
      @bearox8302 2 หลายเดือนก่อน +3

      @@mikoajciemiega8018 Ohhh you little jumping spider you used my compound!? You are getting sued

  • @nicholassoultanian5455
    @nicholassoultanian5455 4 ปีที่แล้ว +592

    Someone give this guy a like a giant research fund. he deserves it.

    • @diamond4xe734
      @diamond4xe734 4 ปีที่แล้ว +14

      IKR dis crap is insane

    • @minermortal1997
      @minermortal1997 4 ปีที่แล้ว +22

      Where’s Oscorp when you need’em

    • @EmmaHopman
      @EmmaHopman 4 ปีที่แล้ว +6

      Patreon

    • @fuckdeadfaces
      @fuckdeadfaces 4 ปีที่แล้ว +3

      @@theunknowngamer5477 You know those movies are fake right lol

    • @fleurgymcheurgy9267
      @fleurgymcheurgy9267 4 ปีที่แล้ว +8

      @@fuckdeadfaces for now...

  • @JoelCreates
    @JoelCreates 4 ปีที่แล้ว +5445

    I'll be following the development closely since, you know, I'm something of a scientist myself...

    • @kenzima6934
      @kenzima6934 4 ปีที่แล้ว +92

      Lmao when is the Hot Glue Web shooter swinging video coming up?

    • @ivoryas1696
      @ivoryas1696 4 ปีที่แล้ว +28

      Joel Creates
      I wanna say same, _but..._ I don't know calculus yet (among many _many_ other things that would likely leave me a bumbling fool in most any *_real_* lab) 😞.

    • @JoelCreates
      @JoelCreates 4 ปีที่แล้ว +82

      @@ivoryas1696 I was referencing the Spider-Man meme, since I recently built a hot glue web shooter. Technically I'm a musician...

    • @ivoryas1696
      @ivoryas1696 4 ปีที่แล้ว +21

      @Joel Creates
      Neato! I'll check it out.
      -Also, I'm somewhat of a musician myself!-

    • @norlavine
      @norlavine 4 ปีที่แล้ว +11

      Me too - my latest project is observing the time it takes to cook a '3 minute egg'.

  • @tatianatub
    @tatianatub 4 ปีที่แล้ว +346

    "the plasmid has been shared on my github repo for that want to mess around with it"
    imagine saying that sentence to someone in genetic engineering 25 years ago

    • @otheraccount5252
      @otheraccount5252 4 ปีที่แล้ว +34

      well, we didn't have git back then

    • @ArnoldsKtm
      @ArnoldsKtm 4 ปีที่แล้ว +10

      @@otheraccount5252 NO SHIT SHERLOCK

    • @recklesflam1ngo968
      @recklesflam1ngo968 4 ปีที่แล้ว +3

      @@otheraccount5252 wow really

    • @Josuh
      @Josuh 4 ปีที่แล้ว +6

      @@otheraccount5252 Really???? I thought github was like hundreds of years old omg thank you

    • @theawsomnessdude
      @theawsomnessdude 4 ปีที่แล้ว +7

      @@Josuh the whacky part is that this sentence might someday be true.

  • @ShDw-cc1bs
    @ShDw-cc1bs 3 ปีที่แล้ว +148

    So what is the current status of this project? Have you scaled up the process and/or have enough of a sample to play around with for a video demonstration?
    Would be incredibly interested in obtaining a sample of the yeast for a related personal project (involving kombucha SCOBY bacteria) if at all possible.

  • @ViktorVano
    @ViktorVano 3 ปีที่แล้ว +867

    I am a software developer, but I am totally amazed how advanced and well understood biochemistry is.

    • @instantnoodles8640
      @instantnoodles8640 2 ปีที่แล้ว +61

      I am a teenager, but I am totally amazed how advanced and well understood biochemistry is.

    • @themblue8236
      @themblue8236 2 ปีที่แล้ว +85

      I am an idiot, but I am totally amazed how advanced and well understood biochemistry is.

    • @philcollinslover56705
      @philcollinslover56705 2 ปีที่แล้ว +9

      @@themblue8236 lmaoo

    • @mastershooter64
      @mastershooter64 2 ปีที่แล้ว +52

      I am a biomolecule, but I am totally amazed how advanced and well understood I am

    • @johndawson6057
      @johndawson6057 2 ปีที่แล้ว +11

      @@mastershooter64 you win this thread

  • @crackedemerald4930
    @crackedemerald4930 4 ปีที่แล้ว +672

    *shakes yeast vigorously*
    "they're a bit of a diva ngl"

  • @TechIngredients
    @TechIngredients 4 ปีที่แล้ว +766

    As fellow You Tubers we continue to try to improve our content aware of the friendly "competition". You keep raising the bar...Damn
    Excellent video, keep it up!

    • @thethoughtemporium
      @thethoughtemporium  4 ปีที่แล้ว +56

      Thanks!!

    • @eatonkuntz
      @eatonkuntz 4 ปีที่แล้ว +2

      hey Tech Ingredients I love your channel too

    • @VengeanceCore
      @VengeanceCore 4 ปีที่แล้ว

      @@communist754 lol

    • @spambotbro839
      @spambotbro839 4 ปีที่แล้ว +4

      @@thethoughtemporium You should collab with NileRed

    • @bmxscape
      @bmxscape 4 ปีที่แล้ว +1

      @@communist754 why would he collab with someone who no one knows xD he doesnt even know if you know anything about the topic

  • @regulargreg
    @regulargreg 2 ปีที่แล้ว +8

    I had a professor in college. This is the kind of project he was barking about in his often encouraged tangents during biopolymer class. Your project is like a customized and detailed exploration that goes well beyond what he could elaborate on in class. Thank you for peaking my interest!

  • @TheMysticGauntlet
    @TheMysticGauntlet 4 ปีที่แล้ว +432

    Peter Parker : No one can figure out my super secret spider web recipe.
    The Thought Emporium : Hold my beer.

    • @uxleumas
      @uxleumas 4 ปีที่แล้ว +6

      isn't all beer made out of yeast though?

    • @bovanshi6564
      @bovanshi6564 4 ปีที่แล้ว +61

      Hold my spider beer*

    • @pete8420
      @pete8420 4 ปีที่แล้ว +4

      Hold my test tubes

    • @TheMysticGauntlet
      @TheMysticGauntlet 4 ปีที่แล้ว +22

      @@bovanshi6564
      Spiderbeer Spiderbeer...
      Does everything a spider can...
      Make a web? Anytime...
      Look out...
      Here comes the Spiderbeer...

    • @SquaredSmith
      @SquaredSmith 4 ปีที่แล้ว +24

      Hold my beer but don't drink it. It's full of spider silk and tastes terrible.

  • @ElderSign32
    @ElderSign32 4 ปีที่แล้ว +191

    it's insane that this is even possible. i feel like a caveman listening to this

  • @kentvandervelden
    @kentvandervelden 4 ปีที่แล้ว +203

    Pretty cool, and there's more power in presenting on TH-cam instead at academic conferences.

    • @Barskor1
      @Barskor1 4 ปีที่แล้ว +10

      But my tenure!

    • @philanthropicnightmare1206
      @philanthropicnightmare1206 4 ปีที่แล้ว +34

      A lot more. Get ready for an influx of scientists making TH-cam channels.

    • @icdeamons112
      @icdeamons112 4 ปีที่แล้ว +11

      'With great power, comes great responsibility.

    • @catwithagun902
      @catwithagun902 4 ปีที่แล้ว +3

      @@blackjoker2345 REALLY great profit margins

  • @reedbrooks3887
    @reedbrooks3887 4 ปีที่แล้ว +362

    Spiders: You will never be able to farm our silk...
    Humans: Ok, we’ll just steal your genes and put them in other organisms.

    • @Salt_discriminater
      @Salt_discriminater 4 ปีที่แล้ว +70

      Hippity hoppity your genes are my property

    • @nightelfmohawk9821
      @nightelfmohawk9821 4 ปีที่แล้ว +5

      Surely nothing can go wrong when mankind tampers with nature...
      GMO is scary stuff

    • @fred_e
      @fred_e 4 ปีที่แล้ว +17

      @@nightelfmohawk9821 Well, I mean, spiders are scary too, I guess.

    • @fred_e
      @fred_e 4 ปีที่แล้ว +21

      @@nightelfmohawk9821 And chihuahuas

    • @lolgamez9171
      @lolgamez9171 4 ปีที่แล้ว +13

      @@nightelfmohawk9821 k but, how is farming spider silk dangerous

  • @wataruishihara1570
    @wataruishihara1570 4 ปีที่แล้ว +2104

    I’m just sitting here wondering how Peter Parker did all of this

    • @BRONZETOAST
      @BRONZETOAST 4 ปีที่แล้ว +118

      I'm wondering why I've been searching for a Spiderman comment. Thank you

    • @lordofhnajuty
      @lordofhnajuty 4 ปีที่แล้ว +100

      Same as tony, with a box of scraps but in a slightly nicer apartment.

    • @brdiejustvibin143
      @brdiejustvibin143 4 ปีที่แล้ว +34

      did it in high school too ..,like how

    • @EthanbloxBiggestFan
      @EthanbloxBiggestFan 4 ปีที่แล้ว +18

      The excuse is that Peter feels the necessity of making spider silk so that’s why he can make it? It’s really weird if I’m honest

    • @gavinhicks7621
      @gavinhicks7621 4 ปีที่แล้ว +45

      Well Toby McGuire his webs were natural Andrew Garfields were stolen from oscorp and Tom Holland I don’t know but I’m pretty sure in the comics (I’ve never read them so this might be wrong) the spider bite gave him the formula composition and he was able to buy the products to make it

  • @TacetCat
    @TacetCat 4 ปีที่แล้ว +515

    My mind is blown. I knew bioengineering was a field that existed, but had never *really* thought about it. When I watch a video on chemistry or physics, I usually get most of it. I understand enough about chemistry to usually follow along with whatever video I'm watching, even if it goes to the slightly more technical side of things.
    *This* video was 33 minutes of me going "wat." Okay, making yeast produce things. I've heard of that. Wait, you can just write DNA like you're a programmer? Wait, there are companies that will print DNA projects for you? This is common enough that a business can be made for it? Wait, you're taking a bunch of different genes and randomizing them and somehow you get the properties you want? Oh, silk sort of doubles back on itself for added strength; I get th- Wait, you can just add properties to it like it's a new spell in a video game? Wait...
    Suffice it to say, I think the remainder of my day is going to be spent learning as much as I can about this. Fascinating is too weak a word.

    • @neut1121
      @neut1121 4 ปีที่แล้ว +29

      that's exactly what was going on in my mind watching this video

    • @HELL0RWIN
      @HELL0RWIN 4 ปีที่แล้ว +13

      Yep. I feel totally the same. I want to know more.

    • @TheMightyZwom
      @TheMightyZwom 4 ปีที่แล้ว +7

      Same here... just... wow...

    • @nikkoa.3639
      @nikkoa.3639 4 ปีที่แล้ว +2

      You've found your resolve my friend.

    • @Someone-ig7we
      @Someone-ig7we 4 ปีที่แล้ว +6

      IKR it's like a game xD. You can just add whatever you want??? Lmao sign me up!

  • @Jeff-ti4pd
    @Jeff-ti4pd 2 ปีที่แล้ว +8

    Man im so happy for you! I watched the first video a couple years ago and I was very anticipating the final and finished product! Congratulations on figuring it out and getting it to work!

  • @kastiak06
    @kastiak06 4 ปีที่แล้ว +524

    "New merch coming soon! Who wants some homegrown T-shirt?!"

    • @billeethesciencegeek
      @billeethesciencegeek 4 ปีที่แล้ว +32

      "I love it so much, I can't seem to take it off!"

    • @GuilhermeCargnelutti
      @GuilhermeCargnelutti 4 ปีที่แล้ว +11

      The yellow ones are edible, but don't try the blue ones

    • @Scott_C
      @Scott_C 4 ปีที่แล้ว +5

      Only $9,999.00. 😄🤑

    • @pablozurita2996
      @pablozurita2996 4 ปีที่แล้ว +2

      @@GuilhermeCargnelutti I'm gonna eat the blue one

    • @tryplot
      @tryplot 4 ปีที่แล้ว +3

      the colors wouldn't even need to be dyed. they could actually be from the silk it's self

  • @nezgroul666
    @nezgroul666 4 ปีที่แล้ว +92

    As a molecular biologist, the explanations in this video are better than most of my uni courses. Difficult principles made simple. Explaining something so that someone uninitiated can understand is a gift. Kudos for the job well done, your countless hours spent on this project were not in vain, sir!

  • @natorious314
    @natorious314 3 ปีที่แล้ว +628

    I can't express how much I love that you document all this content for us to watch. Science in all fields can be so interesting, but it's so insular and stuck in the world of papers and journals that the average citizen will never hear about all the cool shit going on. You and many other science youtubers are really doing a great service.

    • @3asianassassin
      @3asianassassin 3 ปีที่แล้ว +3

      It's often that insularity that convinces people to take up and believe pseudoscience and eventually erode trust in science and data

    • @tbs0000
      @tbs0000 3 ปีที่แล้ว +6

      You call fax I mean we are all forced so deep into the thought that science is all boring stuff on paper but no it's fun aswell like artificial meat or aerogel and theories like our universe isn't finite and it's a loop from one point to another or that aerogel can be used in rockets as insulators.

    • @assfuckerthejointpounder5834
      @assfuckerthejointpounder5834 2 ปีที่แล้ว +1

      I remember how in the action lab they mentioned that the structural strength of steel regarding tensile strength is in the gigapascals. Even specialized steel it's not like it's 10,000 times which spider silk can handle or whatever. Who knows how many creatures have a shell made out of nacre oh, it's tensile strength depending on the species is 170 gigapascals, even if one gigapascal is 2 megapascals this is still a whole lot more than steel. The trouble is this bad boy takes 170 gigapascals to bend, or is that bend it to a point that it will no longer Bend back. Either way that is a whole lot. I did the conversion for both of those, 170 gigapascals is more than 24 million pounds per square inch, and 70 is more than ten million. I did the conversion for both, I checked the conversion multiple times for the tensile strength. I'm pretty sure that I did the 70 kg pascals correctly given how much of it was copying and pasting, and using an online calculator. This is far beyond Steel. Now this is so strong because of the way that it is aligned, according to Google it's like more than 300 or something times stronger than the material it's made out of. So imagine graphene was in the structure that this material is in. And I'm not talking about the structure of which its atoms are aligned. This bad boy is made in a structure of pretty much interlocking tiles, so imagine this was what was going on with a flat thing of the functionally two-dimensional graphene oh, that bad boy would be incredible however graphene is very flexible so this might defeat the purpose. However something tells me that if the graphene were to be bio mineralized to be interwoven with the nacre be beneficial.

  • @darkestwilightt
    @darkestwilightt 3 ปีที่แล้ว +8

    23:42
    "Thing number one.... be gentle with the yeast...."
    I just love the way he said that

  • @Gennys
    @Gennys 4 ปีที่แล้ว +348

    Someone needs to explain to me how any natural, unmodified living organism can have patents put on their genes in the first place...

    • @btw1095
      @btw1095 4 ปีที่แล้ว +83

      Brian thats what we get in a a country run by corporations

    • @ahtheh
      @ahtheh 4 ปีที่แล้ว +9

      Huh
      I've been learning that sht to get marks from the 9th Grade and now I can use that knowledge to brag to a random guy on the internet because I know it and he doesn't
      [I now realize that's all that information is every going to be useful for]

    • @senjugold6977
      @senjugold6977 4 ปีที่แล้ว +48

      Lmao imagine existing and the big companies are like: "your genes are mine!"

    • @Larantula
      @Larantula 4 ปีที่แล้ว +13

      Kinda reminds me of the tree that legally owns both itself and the land around it.

    • @onidaaitsubasa4177
      @onidaaitsubasa4177 4 ปีที่แล้ว +3

      I know right, it seems that there would be some legal trouble with whoever made the patent and the original genetic designer of the animals, or would the actual spider be the patent holder of the silk since it originally created it, either way it doesn't exactly seem legal.

  • @ShamelessDuck
    @ShamelessDuck 4 ปีที่แล้ว +218

    I can't imagine I live in the time when THIS is possible. You are in my "God-Tier TH-camrs" list

    • @tormodhag6824
      @tormodhag6824 4 ปีที่แล้ว +4

      ShamelessDuck like you can print DNA?! that is kinda crazy, just humans writing their very own DNA designed specifically to hijack in this example yeast. I searched DNA printing on google and you can apparently make custom creatures with it, which is insane

    • @ShamelessDuck
      @ShamelessDuck 4 ปีที่แล้ว +2

      @@tormodhag6824 I dream of future when we will use GMOs legally in our everyday life without it being marketed as "non-GMO" and without this whole stigma around it.

    • @puppypi9668
      @puppypi9668 4 ปีที่แล้ว

      Ikr
      And I love how the God-Tier TH-camrs all know each other XD
      Applied-"I built a scanning electron microscope from scratch in my shop"-Science and Tech-"I made a nanostructure imprinted chocolate bar diffraction grating"-Ingredients both commented here alongside us! XD

  • @acompletelynormalhuman6392
    @acompletelynormalhuman6392 4 ปีที่แล้ว +55

    Congratulations I know you've been working on this project for a while and it's really exciting to see you succeed

  • @samdwichenjoyer
    @samdwichenjoyer 2 ปีที่แล้ว +3

    Rewatching this video a second time and chuckled thinking about how people used to think everything was made of air, water, fire, and earth, and here you are doing this sorcery

  • @Hlebuw3k
    @Hlebuw3k 4 ปีที่แล้ว +185

    "I was able to purchase a whole vile of nightmare fuel for a grand total of 15 dollars"
    I did not need to know the price of an arachnophob's sanity.

    • @minermortal1997
      @minermortal1997 4 ปีที่แล้ว +17

      Secret Santa gone hardcore

    • @knctvrknctvr
      @knctvrknctvr 4 ปีที่แล้ว

      @@minermortal1997 now THATS what I call an office party!

  • @legendarysideburns2213
    @legendarysideburns2213 4 ปีที่แล้ว +584

    Next project: yeast that makes spiders

    • @sleezymechanic
      @sleezymechanic 4 ปีที่แล้ว +77

      Next next project: spiders that make beer

    • @notajalapeno4442
      @notajalapeno4442 4 ปีที่แล้ว +24

      @@sleezymechanic next next next project:yeast that makes dimonds

    • @cg_pizza
      @cg_pizza 4 ปีที่แล้ว +17

      @@notajalapeno4442 next next next next project: yeast that make any material

    • @NewsChannel-y4g
      @NewsChannel-y4g 4 ปีที่แล้ว +16

      next project: watch youtube and feel like I have done something

    • @NewsChannel-y4g
      @NewsChannel-y4g 4 ปีที่แล้ว +12

      next project: clean kitchen

  • @aflyingpumpkin1073
    @aflyingpumpkin1073 4 ปีที่แล้ว +264

    This was the fastest I have ever clicked on a notification.

  • @patrickhayes3099
    @patrickhayes3099 ปีที่แล้ว +1

    Glad to see this! 40 years ago I walked through a black widow web and began wondering about how to harvest the silk to make fabric.

  • @crookeddesk
    @crookeddesk 4 ปีที่แล้ว +154

    "I've become quite competent at designing DNA from scratch"
    "and just have a company PRINT the DNA"
    Jesus christ watching your videos always makes me awe at the times we live in...

    • @kingbroseph9773
      @kingbroseph9773 4 ปีที่แล้ว +9

      wait till he can print his own DNA without a company

  • @Blaze22F
    @Blaze22F 4 ปีที่แล้ว +51

    *28:05** this moment left a big smile on my face*
    *Congrats my guy*

  • @venus1051
    @venus1051 4 ปีที่แล้ว +89

    I'm an art student but I'm sitting here, 5:15 pm, watching a man make spider's silk out of yeast.
    This is the coolest shit I've seen all day dude. Can't wait to see what you come up with next. Love the mad science bro.

  • @BeaChapman
    @BeaChapman ปีที่แล้ว +22

    I still can't believe people can write DNA in Google docs. I hope to do that someday.

  • @booker...
    @booker... 4 ปีที่แล้ว +721

    Haha that spiders pretty hot amiright guys

    • @BitterTast3
      @BitterTast3 4 ปีที่แล้ว +37

      Can't wait for the video on "spidey-sense".

    • @0th_Law
      @0th_Law 4 ปีที่แล้ว +6

      @@BitterTast3 The real question: how would you go about achieving it?

    • @bleachisgoodforu9341
      @bleachisgoodforu9341 4 ปีที่แล้ว +14

      Get bit by every spider

    • @LOOTS243
      @LOOTS243 4 ปีที่แล้ว +2

      Spiderboiii

    • @ViktorTheMusician
      @ViktorTheMusician 4 ปีที่แล้ว +8

      @@0th_Law Tarantula DNA? They use their hair to detect changes in the air. Spidey Sense was meant more to represent an invisible web of sorts, though I've also seen it as representing the 8 eyes spiders have though they actually have really bad eyesight. But by coincidence Tarantulas already have a spidey sense going for them.

  • @Ryan6.022
    @Ryan6.022 4 ปีที่แล้ว +67

    Spidey yeast
    Spidey yeast
    Produces proteins a spider can
    Makes a fiber any size, matches kevlar any time
    Look out here comes the spider yeast
    Is it strong? Listen bud,he's got enhanced gene strands.
    Can it be made into a thread? Take a look over head.
    Hey there goes the spider yeast!

  • @transformerslov
    @transformerslov 4 ปีที่แล้ว +408

    Its so weird. He makes me feel like I can understand everything he is saying but at the same time I'm like
    👁👄👁 okay 👍

    • @mechadonia
      @mechadonia 3 ปีที่แล้ว +22

      4 mins in “what is he even talking about”
      20 mins in “of course the pPCI9k needs to be linearized with a restriction enzyme! You can’t have those DNA rings, duh!!!”

    • @auve0G
      @auve0G 3 ปีที่แล้ว +1

      it sounds like foreign language

    • @nateracing
      @nateracing 3 ปีที่แล้ว +2

      I interpreted this as an informal video-essay type of report on his findings, truly fascinating, yet extremely confusing to people without bio-majors, like me ;)

  • @FSantora
    @FSantora ปีที่แล้ว +2

    I can't believe you were able to explain this in a way I almost completely understand! I learned SO MUCH from this!

    • @FSantora
      @FSantora ปีที่แล้ว

      I would be interested in where LOTUS silk falls on the graph at 10:10

  • @colby3896
    @colby3896 3 ปีที่แล้ว +290

    I’m actually amazed at how much of your research I understood as a freshman biochem major. Stuff like this makes me hopeful that I could potentially make a career out of genetics because before college, I really doubted my ability to be successful in the field

    • @jadenmead1928
      @jadenmead1928 3 ปีที่แล้ว +14

      never doubt yourself ;)

    • @ninjadel2
      @ninjadel2 2 ปีที่แล้ว +5

      As a recent physiology grad this makes me hopeful to one day start working on unique avenues of research as well

    • @dgs_susave1324
      @dgs_susave1324 2 ปีที่แล้ว

      Keep going. Who knows. You may pull a TASM again with the genetic spider 😂don’t give up on your dreams‼️

    • @assfuckerthejointpounder5834
      @assfuckerthejointpounder5834 2 ปีที่แล้ว +1

      Well if you want to make something like Godzilla be realistic then try using biomineralization to put nacre in its bones and scales oh, you probably want pockets of stuff like methane in there, methane is a gas produced by living things the most common example that not many people might necessarily know has it in there is when you fart. But farting is made by the methane or swallowed air, by making it have nacre the bones would take literally millions of pounds to not only Pull-A-Part but also Bend, or is that bend it to a point that it will no longer be able to bend back to its original shape. The tensile strength is 170 gigapascal, there are 70 for its strength for the bending thing. 170 gigapascals after I checked my conversion this correctly comes out to more than 24 million pounds per square inch, even if you use the metric system that is obviously a very high amount. The action lab which is a another Dependable source of science information said that steel is generally in the megapascal range, it takes a lot of megapascals to make a single gigapascal. And if its skin is made out of graphene, or whatever term is used for the soft flexible stuff that is what is responsible for holding the scales together on the skin of a snake or lizard. That bad boy would be very durable, for context just some graphene that is the size of Saran Wrap would require Force equivalent to a fully grown male African elephant balancing on a pencil. Not to mention that the Wonder material is also a very effective superconductor so you could probably use this to get rid of the issue of the Godzilla that is more than 100 m tall taking more than a second for anyting to register in its brain because the electricity take so long to move through the body. This graphene could eliminate that issue oh, so we could react without needing to be 15 M tall at maximum. And if it's hunched over like your average T-rex or Utahraptor this could help with blood flow at such a gargantuan scale. And if you argue that it doesn't have enough energy from the atmosphere to oxygenate it, there is an organism that can survive without any oxygen, also considering out at our degraded can literally live for multiple days in the vacuum of space. Something tells me there's probably the required already existing genetics somewhere in the world to let something survive at such a gargantuan scale. But maybe not after all a hundred meters is a very high number for the size of an organism on Earth.

    • @Ideas795
      @Ideas795 2 ปีที่แล้ว +1

      Nice👍 I plan on majoring in biochem

  • @PauloOlveira
    @PauloOlveira 3 ปีที่แล้ว +237

    Just leaving this out here: A silk/graphene composite generating yeast that survives high salinity would be prime candidate for regenerating tidal turbines

    • @ninjanyan1579
      @ninjanyan1579 ปีที่แล้ว +57

      I understood all of those words separately and am proud of myself for that.

    • @ThisLockIsJammed
      @ThisLockIsJammed ปีที่แล้ว +23

      If this is true, on top of making it a commercial clothing or building material, this guy could be looking at a Nobel.

    • @wedmunds
      @wedmunds ปีที่แล้ว +11

      I think that could do a lot more than just repairing turbines

    • @thecallankids4718
      @thecallankids4718 ปีที่แล้ว

      While it could do that, would it not also coat the ocean floor in carbon doped silk?

    • @Gigan--a
      @Gigan--a 11 หลายเดือนก่อน +3

      @@thecallankids4718that I’d assume degrades faster than thousands of years

  • @ramabary
    @ramabary 4 ปีที่แล้ว +189

    Make the web cure faster is hard enough. Let alone:
    1. It can carry the man size weight
    2. Produce a length of string
    3. Infinite strings.

    • @sonofanutcracker4207
      @sonofanutcracker4207 4 ปีที่แล้ว +52

      4. Become spiderman

    • @darknobz3560
      @darknobz3560 3 ปีที่แล้ว +25

      @@sonofanutcracker4207 5. Great responsibility

    • @urtooslow4415
      @urtooslow4415 3 ปีที่แล้ว +17

      @@darknobz3560 great stress and late rent debt

    • @benbruder
      @benbruder 3 ปีที่แล้ว +10

      @@urtooslow4415 7. *MENACE!!!!*

    • @praddhyumnmani7925
      @praddhyumnmani7925 2 ปีที่แล้ว +4

      @@benbruder 8. Get forgotten by everyone

  • @harrisoncord3680
    @harrisoncord3680 3 ปีที่แล้ว +14

    make a web shooter and only if the silk was strong enough, you could be spiderman.

  • @giacomoarturogrelli8904
    @giacomoarturogrelli8904 3 ปีที่แล้ว +103

    This is huge, it's amazing how you managed to succeed, this sounds like science fiction and yet you made it reality, I admire you

  • @Palitato
    @Palitato 4 ปีที่แล้ว +514

    "I couldn't isolate the DNA, so I just made it myself."

    • @davidmella1174
      @davidmella1174 4 ปีที่แล้ว +12

      ...

    • @aferrone92
      @aferrone92 4 ปีที่แล้ว +28

      I literally lost it when he said that

    • @ProctasisLimerna
      @ProctasisLimerna 4 ปีที่แล้ว +31

      I will make my own DNA with hookers and blackjack

    • @Lucas-iSL
      @Lucas-iSL 4 ปีที่แล้ว +4

      @@ProctasisLimerna and without the N.A.T.O!

    • @minermortal1997
      @minermortal1997 4 ปีที่แล้ว +9

      @@ProctasisLimerna this sounds like a Cave Johnson quote.

  • @altofmoleperson
    @altofmoleperson 4 ปีที่แล้ว +307

    Why am I watching this, my experience with biology is “the mitochondria is the powerhouse of the cell” and “sometimes, plants eat the sun.”

    • @imcoolerthanallofyou7751
      @imcoolerthanallofyou7751 4 ปีที่แล้ว +40

      I’m imagining a plant just biting a giant chunk out of the sun

    • @altofmoleperson
      @altofmoleperson 4 ปีที่แล้ว +25

      @@joshuanetanel9174 Of course, the kale kills.

    • @Grumpy_old_Boot
      @Grumpy_old_Boot 4 ปีที่แล้ว +11

      Soylent green is people too.

    • @patricknkwo652
      @patricknkwo652 4 ปีที่แล้ว +5

      lol, same, I'm just curious to see what emerges in the next 25 years from him & this field

    • @hahayoucantstopmehawokenha4059
      @hahayoucantstopmehawokenha4059 4 ปีที่แล้ว +5

      i would love to see a plant eating the sun

  • @JeskaDax
    @JeskaDax 2 ปีที่แล้ว +1

    Been following your progress on this for so long. It's awesome to hear you're over that major hurdle!
    I look forward to hearing how the rest of your experiments go!

  • @nerobaal6655
    @nerobaal6655 13 วันที่ผ่านมา +1

    This has progressed my work farther and faster than I was hoping for. I appreciate your work and I thank you.

  • @user-N20
    @user-N20 4 ปีที่แล้ว +805

    All the people who want to be Spiderman: *_confused but encouraged_*
    "Write that down! Write that down!"

    • @jameskelly9277
      @jameskelly9277 3 ปีที่แล้ว +21

      Lmaooo why would you call me out like this!!

    • @nightastheold9094
      @nightastheold9094 3 ปีที่แล้ว +21

      Lol I was in 7th grade and the 2002 Spider-Man came out. My friend and I thought we could make web shooters from aluminum cans and webbing from kitchen spices and cleaners.

    • @alionicle
      @alionicle 3 ปีที่แล้ว +1

      Aight, that's me right now

    • @Eatmywalnutz
      @Eatmywalnutz 3 ปีที่แล้ว +7

      I want to make a web shooter

    • @kete6640
      @kete6640 2 ปีที่แล้ว +3

      Ive been tryna figuring out how to be spider man for the past 3 yrs lol, and I DIDN’T RUN A SINGLE TEST BECAUSE 12 YR OLDS CAN’T GET A HOLD OF NYLON 6, 10 SILICONE AND ADHESIVE GEL. I ALSO WANTED TO ADD HIS SPIDER SILK LIQUID THING BUT I’M TO “UN-INTELLIGENT” TO MAKE IT. AND DON’T ASK WHY I’M YELLING BECAUSE IDK

  • @ziggiey
    @ziggiey 4 ปีที่แล้ว +161

    All i can imagine is him looking at the genetic code and going "mmmm, silky"

  • @Funlifedoga
    @Funlifedoga 4 ปีที่แล้ว +49

    We have been waiting for this for sooo long!!!

  • @lancewalker2595
    @lancewalker2595 2 ปีที่แล้ว

    This is by far the most incredible, most inspiring thing I've ever seen. People like you are the future, I truly believe that. Unbelievable.

  • @ganf
    @ganf 4 ปีที่แล้ว +66

    23:07 Stuff like this is why I love the internet. It's so nice to see researchers come together and help each other out :)

  • @LizardWizard1005
    @LizardWizard1005 3 ปีที่แล้ว +207

    "A whole vial of nightmare fuel" I've never heard that be so damn accurate

    • @BahhBahhBrownSheep
      @BahhBahhBrownSheep 11 หลายเดือนก่อน

      I’m pretty sure that’s a statement you’ve never heard before, or in the two years since. So that’s not particularly impressive

    • @passingrando6457
      @passingrando6457 10 หลายเดือนก่อน

      ​@@BahhBahhBrownSheepCounterpoint: the Pony Jar Project exists.

  • @kingarthurthe5th
    @kingarthurthe5th 4 ปีที่แล้ว +47

    Giving a whole new meaning to “silky smooth beer”

  • @MaleniaLi
    @MaleniaLi หลายเดือนก่อน +1

    It’s crazy going from “wow that’s pretty cool, no idea how you did that, but it’s cool” when watching science TH-cam to “huh, I did something similar in class last week, cool!”

  • @defectivetoaster7713
    @defectivetoaster7713 4 ปีที่แล้ว +247

    Everyone here who has no clue what you’re saying just going along like “ah yes the graphene binding peptides have worked”

    • @0th_Law
      @0th_Law 4 ปีที่แล้ว +24

      It's actually decently intuitive. If the yeast produces a protein with the ability to bind graphene, then the graphene oxide will naturally coagulate around the proteins, and therefore the yeast, because it is being bound to the proteins.

    • @TheIdiotFr0102
      @TheIdiotFr0102 4 ปีที่แล้ว

      @@0th_Law hUh 😐

    • @0th_Law
      @0th_Law 4 ปีที่แล้ว +1

      @@TheIdiotFr0102 If you want, I can clarify stuff for you; just tell me what doesn't make sense. (This is assuming that you mean that what I wrote didn't make sense. If that isn't the case, then never mind.)

    • @TheIdiotFr0102
      @TheIdiotFr0102 4 ปีที่แล้ว

      @@0th_Law you said some smart stuff but I think this comment is meant to be a joke and you added some smart stuff to it, so idk

    • @0th_Law
      @0th_Law 4 ปีที่แล้ว

      @@arrowsaurus7561 You're going to have to be more specific than that. Otherwise, the answer will probably just be something like "Cell Signaling" or "Conformational Changes"

  • @Z31HoodMoments
    @Z31HoodMoments 4 ปีที่แล้ว +115

    “Was able to purchase a whole vile of nightmare fuel”

  • @tinnfinn7293
    @tinnfinn7293 4 ปีที่แล้ว +314

    Everyone watching this that has no idea what he’s saying: “You know, I’m something of a scientist myself.”

    • @estebancino5426
      @estebancino5426 4 ปีที่แล้ว +2

      ¿Is that that a Raimi reference?

    • @cleosvoyage
      @cleosvoyage 3 ปีที่แล้ว +5

      @@estebancino5426 no.

    • @nicholass5621
      @nicholass5621 3 ปีที่แล้ว +4

      @@cleosvoyage yes - the quote is from sam raimi's spiderman movies

    • @ytshorts9609
      @ytshorts9609 3 ปีที่แล้ว

      I studied abt genetic engineering

    • @DamianDeEu
      @DamianDeEu 3 ปีที่แล้ว

      @@ytshorts9609 I studied the entire ABC of English alphabet and got it all memorised now! Pretty cool, huh? 😎

  • @huntercool2232
    @huntercool2232 2 ปีที่แล้ว +6

    “I grew real spider silk using yeast!”
    *Peter Parker wants to know your location*

  • @baldiesss
    @baldiesss 4 ปีที่แล้ว +143

    Type of guy to clone himself and go on vacation and we won't notice

  • @KiJ0_0
    @KiJ0_0 4 ปีที่แล้ว +130

    Spider-Man’s web fluid is now becoming a reality

    • @zmalque
      @zmalque 4 ปีที่แล้ว +4

      FAVIAX Delatorre hol up

    • @alejandrobernal4987
      @alejandrobernal4987 4 ปีที่แล้ว

      Indeed it is, my friend

    • @Josuh
      @Josuh 4 ปีที่แล้ว

      @FAVIAX Delatorre 😤😤😤ಠ‿ಠ

    • @nikkiofthevalley
      @nikkiofthevalley 4 ปีที่แล้ว +1

      @FAVIAX Delatorre That's f**ked up.

    • @KiJ0_0
      @KiJ0_0 4 ปีที่แล้ว +2

      FAVIAX Delatorre get out.

  • @bumpket
    @bumpket 4 ปีที่แล้ว +54

    The dislikes are just the other spiders being jealous about this amazing silk.

    • @greengreen110
      @greengreen110 4 ปีที่แล้ว +1

      And the big corps geting mad because the plasmid is open source

  • @blueechodragon99
    @blueechodragon99 7 หลายเดือนก่อน +2

    11:00 thanks to high school biology, I can actually understand this. Thanks for showing a interesting use for the stuff we are learning!

  • @nutsandbolts1264
    @nutsandbolts1264 4 ปีที่แล้ว +194

    This guy: *invents yeast spider silk*
    Everybody: SPIDERMAN SPIDERMAN DOES WHATEVER A SPIDER CAN

    • @erumaaro6060
      @erumaaro6060 4 ปีที่แล้ว +1

      it does add another meaning to "spider can", right?

    • @kiriki4558
      @kiriki4558 4 ปีที่แล้ว +2

      Yeah, i was especting that. But i'm more interested in the practical use of spider silk, cause it's resistance is legendary.

    • @erumaaro6060
      @erumaaro6060 4 ปีที่แล้ว

      @@kiriki4558
      I was referring to a Beer-CAN full of silk. (assuming you are replying to my comment that is)
      The practical applications are a no brainer.
      10 years ago i would have shelved this under sci-fi, jet here you are actually doing it.
      btw, the biomineralisation feature sounds amazing. I cant even imagine what properties spider silk bonded to carbon nanotubes would have, but i'm sure it would get you out of a sticky situation, or create them for that matter.

  • @pvc988
    @pvc988 4 ปีที่แล้ว +231

    "First, its silk gene wasn't protected by any patents…"
    Wait, WUT?

    • @Plotatothewondercat
      @Plotatothewondercat 4 ปีที่แล้ว +146

      The first entity to isolate a particular gene gets to file a patent on it under the current biotech regs. Leads to some very undesirable possibilities. It's one reason to be suspicious of those 'we'll analyze your DNA to determine your ancestry/risks' things, because it's potentially a mechanism for someone to gain a monopoly on all commercial use of one of your genes for the next few decades.

    • @wacesferpit
      @wacesferpit 4 ปีที่แล้ว +99

      capitalism

    • @Plotatothewondercat
      @Plotatothewondercat 4 ปีที่แล้ว +56

      @@wacesferpit That's the more succinct explanation yeah.

    • @eichenbrain6170
      @eichenbrain6170 4 ปีที่แล้ว +19

      @@Plotatothewondercat ... and then (after the 20 years) your own personal gene is open to the public to use as they see fit.

    • @Plotatothewondercat
      @Plotatothewondercat 4 ปีที่แล้ว +32

      @@eichenbrain6170 Twenty years after a corporation had the opportunity to raise the price of whatever treatment it may have turned out to be useful for to the point that thousands of potential beneficiaries went past the point of no return without ever having the capability to pay for the treatment.

  • @sarahellis7429
    @sarahellis7429 4 ปีที่แล้ว +60

    I think you did a really good job on the visual side of this video, the diagrams, infographics, tables etc. As a graphic designer I was impressed. Awesome video.

  • @VirtualGobllim47
    @VirtualGobllim47 8 หลายเดือนก่อน +2

    The FACT this all evolved through eons of probability is astounding

  • @shortkinga11Da4
    @shortkinga11Da4 4 ปีที่แล้ว +382

    Everyone’s talking about him using big words. Me thinking how he could be the next Spider-Man

    • @dragonmania1749
      @dragonmania1749 4 ปีที่แล้ว +13

      "Could be used for -coughs and shows picture of spiderman- s p e c i f i c uses"

    • @colonelh1875
      @colonelh1875 4 ปีที่แล้ว +2

      I'm thinking about spider kevlar

    • @noodlesgamebox5903
      @noodlesgamebox5903 3 ปีที่แล้ว +2

      They might not all SAY it, but we were all at least thinking it.

    • @Tom-ku8bu
      @Tom-ku8bu 3 ปีที่แล้ว +1

      I think in the Korean war they used spider silk for an bullet proof vest. But nowadays the bullets have more energy so it doesn't protect anymore

    • @mastere6115
      @mastere6115 2 ปีที่แล้ว

      @cosmify Check the video at 20:25 hahahaha

  • @asmolbean9300
    @asmolbean9300 4 ปีที่แล้ว +122

    Biology brain me: ah yes an excellent video, a true breakthrough, very exciting.
    Normal brain me: hehe pretty colours

  • @GGShinobi77
    @GGShinobi77 4 ปีที่แล้ว +54

    What I also learned: The Web Shooters that Spider-Man uses wouldn't quite work just like that as it's shown in the comics... They would need to produce different kinds of silk depending on the use case... but he always just presses the same button. Still pretty cool though.

    • @ikathesquid0921
      @ikathesquid0921 4 ปีที่แล้ว +21

      newer media of spiderman actually expand upon this by showing that he controls what kind of silk that comes out via tech in his web shooters. like from homecoming when veronica asks him what kind of webbing he wants

    • @ikathesquid0921
      @ikathesquid0921 4 ปีที่แล้ว

      @@arrowsaurus7561 my bad lmao

    • @ikathesquid0921
      @ikathesquid0921 4 ปีที่แล้ว +3

      @@arrowsaurus7561 mixed up hulk buster ai with Pete's

    • @AK-Drakoin
      @AK-Drakoin 4 ปีที่แล้ว

      @Dan Public ……You- by the original version you seem to be implying the Sam Raimi Spider man movies. Which was based on the comics.. The original comics where Spider man used web shooters and couldn’t have webbing organically.
      Ie. No The first movies were not the original version of Spider man

    • @AK-Drakoin
      @AK-Drakoin 4 ปีที่แล้ว +2

      @Dan Public oh no sir I am very sorry! I am sorry for my condescendence and I didn’t mean you any disrespect! I respect the fact that you hold the original films to such a high regard and liked Spidey so much! I completely understand, I merely thought you were someone who held the original comics to no meaning- in where Spidey originally developed his own web shooters (The original films probably decided to have it come out of him for screen time, and because a few other comics later on did have him have that ability)
      I’ll be honest, I thought you were an ignorant nerd 😝 and didn’t realize the whole state of the matter.
      You shouldn’t have to remove your comment because of my own condescendence.
      I wish you the best during 2020 sir! And I hope you live a good life 🙂

  • @santiagomakoszay5090
    @santiagomakoszay5090 6 หลายเดือนก่อน

    I LOVE YOUR VIDEOS, they’re absolutely amazing. I really appreciate that you go through the whole process in detail. It’s really helpful for people not as close to the field :)

  • @choovick
    @choovick 4 ปีที่แล้ว +7

    I have 0 biology and chemistry skills, but I love to see similar concepts and ingenuity you can find in many engineering fields! This is amazing!

  • @shasni626
    @shasni626 4 ปีที่แล้ว +67

    "First: It's silk gene wasn't protected by any patents" whoa whoa whoa, hold on, what? What kind of cyberpunk is this?

    • @herrpez
      @herrpez 4 ปีที่แล้ว +18

      I'm cool with that. Assuming the spiders are the patent holders.
      But that strikes me as being somewhat unlikely.

    • @SomethingSmellsMichy
      @SomethingSmellsMichy 4 ปีที่แล้ว +3

      @@herrpez spider lawyer

    • @datboii2877
      @datboii2877 4 ปีที่แล้ว +6

      @@SomethingSmellsMichy HAHAHAHAHHAHAH
      Spider Lawyer, Spider Lawyer, does whatever a lawyer does, does he defend? Yes he does, he can also climb the laws, watch out here comes Spider Lawyer!

  • @GIRGHGH
    @GIRGHGH 4 ปีที่แล้ว +46

    This whole thing seems almost like a no-brainer in hindsight, dang this is cutting edge.

    • @culinarycow3181
      @culinarycow3181 4 ปีที่แล้ว +3

      The term is bleeding edge

    • @GIRGHGH
      @GIRGHGH 4 ปีที่แล้ว +6

      @@culinarycow3181 I've heard it both ways. Just used the first that came to mind. There are surprisingly many ways to say the same thing sometimes :]

    • @culinarycow3181
      @culinarycow3181 4 ปีที่แล้ว

      @@GIRGHGH bleeding edge refers to thd science as it com out and cutting edge is the newest available technology available to scientists/ what ever specialist is in each feaild

    • @culinarycow3181
      @culinarycow3181 4 ปีที่แล้ว +1

      @@GIRGHGH just for future reference

    • @GIRGHGH
      @GIRGHGH 4 ปีที่แล้ว +5

      @@culinarycow3181 I'm pretty sure the context is what determines if it's for research or technology, not which word you put in front of edge.

  • @Flesh_Wizard
    @Flesh_Wizard ปีที่แล้ว +2

    Mad Scientists in movies: The world will be mine!
    Mad Scientists IRL: spider beer, spider beer, does whatever a spider beer does...

  • @kamilag2791
    @kamilag2791 4 ปีที่แล้ว +7

    I literally wrote about you in my university application. You're the reason I'm going to university. Thank you for creating videos and making them high quality and interesting!

  • @TheDro
    @TheDro 3 ปีที่แล้ว +173

    I have a few bugs as pets as well, if you ever need anything lmk!

  • @guacamole2993
    @guacamole2993 4 ปีที่แล้ว +47

    Oml I am learning this in my AP Bio class as we speak: gene expression. Seeing it used in a real world scenario and having you explain this made my life so much easier! Thank you, and continue doing cool stuff.

  • @aloysiuskurnia7643
    @aloysiuskurnia7643 ปีที่แล้ว +1

    Vortexing nad pipetting up and down is one _hell_ of a difference of force.

  • @ultrapika1875
    @ultrapika1875 4 ปีที่แล้ว +49

    This is actually really interesting. I also sometimes forget that people just do this kinda stuff for fun/a living.

  • @TwistedHound14
    @TwistedHound14 3 ปีที่แล้ว +16

    I honestly didn't understand what you were talking about. But I was intrigued the entire time. I didn't even know it was possible to PRINT DNA. This is some crazy stuff

  • @natureabioros8686
    @natureabioros8686 4 ปีที่แล้ว +17

    This is so cool, as a researcher who works with genetically engineering microorganisms to produce proteins, this is a huge inspiration

  • @Goon1995
    @Goon1995 3 ปีที่แล้ว +5

    Me after watching this video: *"You know, I'm something of a scientist myself."*

  • @calebgebhard7863
    @calebgebhard7863 4 ปีที่แล้ว +247

    Peter Parker: Would Like to Know Your Location

    • @ashketchum6585
      @ashketchum6585 4 ปีที่แล้ว +1

      Underrated comment😂

    • @syntaxusdogmata3333
      @syntaxusdogmata3333 4 ปีที่แล้ว +2

      @@ashketchum6585 Indeed. It could have 10x the likes, and still be underrated.

  • @LaceworkDreams
    @LaceworkDreams 4 ปีที่แล้ว +19

    Man really said "fine. I'll do it myself."

  • @FreaKazaN
    @FreaKazaN 4 ปีที่แล้ว +50

    "Use yeast to produce spider web, hence SPIDER BEER"
    Never have I ever been WTF'ed so fast

  • @Leatherargento
    @Leatherargento ปีที่แล้ว

    There's I love your channel. I'm in my late 40s, and I'm still surprised, and often, by your content.