Multiple Sclerosis and the Myelin Sheath

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  • เผยแพร่เมื่อ 19 มิ.ย. 2024
  • Multiple Sclerosis (MS) is an autoimmune disease that causes signals travelling through our nerves and brain to slow down significantly or stop completely, leading to a wide range of debilitating neurological symptoms. Clearly, neurons are being damaged...but by what? Check out this week's episode of Medicurio to learn more about this disease.
    Medicurio episodes are short and only give a relatively condensed explanation of the disease. To learn more about multiple sclerosis, or to donate to its research, check out the following websites:
    MS Society of Canada: mssociety.ca/
    Multiple Sclerosis Foundation: msfocus.org/
    National Multiple Sclerosis Society: www.nationalmssociety.org/
    In the video, I've simplified the movement of electrical signals because they actually involve more ion channels that open and close in response to each other and the potential. For a more in-depth understanding of these electrical signals, known as action potentials and electrotonic transfer, check out this cool animation by Neuroscience 5e: sites.sinauer.com/neuroscience...
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ความคิดเห็น • 69

  • @drmanakias
    @drmanakias 5 ปีที่แล้ว +15

    ABSOLUTELY perfect examples , 2 years on neurology misunderstood, explained in 10 min . Hope I had professors with your creativity

    • @colour2690
      @colour2690 3 ปีที่แล้ว

      Kudos for the Video! Sorry for the intrusion, I would appreciate your initial thoughts. Have you heard about - Liyaraah Sclerosis Redemption (do a google search)? It is an awesome exclusive product for overcoming the symptoms of multiple sclerosis minus the hard work. Ive heard some amazing things about it and my old buddy Taylor at last got great success with it.

    • @stalinescalante6093
      @stalinescalante6093 3 ปีที่แล้ว

      the talk about - Liyaraah Sclerosis Redemption (google it)? It is a great one off product for overcoming the symptoms of multiple sclerosis without the hard work. Ive heard some pretty good things about it and my good mate called Gray got great results with it.

    • @bobleclair5665
      @bobleclair5665 ปีที่แล้ว

      I’m hearing positive things on vitamin b1

  • @hfof
    @hfof หลายเดือนก่อน

    omg, the way how you illustrated everything is just beyond perfection. I hope you keep going, you've definitely helped so many people, and I hope you keep on making the same cool content. Thank you so much, love and guidance.

  • @stevencross6461
    @stevencross6461 3 ปีที่แล้ว +4

    That video was amazing. The words made sense and the animation was SUPER helpful.

  • @dr.nikolov
    @dr.nikolov 6 ปีที่แล้ว +9

    recently subscribed, very fascinating videos, please do not stop uploading, I believe your channel will grow!

  • @wellnesshearddifferently5920
    @wellnesshearddifferently5920 3 ปีที่แล้ว +6

    interesting video! I love educating myself on this topic! Though I live with MS I hope to learn so much about myelin so that I can improve my piano playing, thinking, walking & my overall life.

  • @fulstop8871
    @fulstop8871 6 ปีที่แล้ว +2

    Excellent video. Really clear presentation. Thanks for making it.

  • @wanda7198
    @wanda7198 5 ปีที่แล้ว +3

    Thank you so much for making this video! Extremely helpful

  • @RossDaBoss1
    @RossDaBoss1 5 ปีที่แล้ว +2

    Amazing explanation, subscribed!

  • @fehmisigindi1498
    @fehmisigindi1498 5 ปีที่แล้ว +2

    Very good explanation. Please keep going this way on the other medical subjects.

  • @J.M..
    @J.M.. 2 ปีที่แล้ว +1

    I wish that you could make more videos. These are great!

  • @TheLivingBreathingWendy
    @TheLivingBreathingWendy 7 ปีที่แล้ว +5

    My mom has MS and I have never understood anything about it. Thank you for making these videos to explain. These videos are so quality! Been watching since the first! (I have CF)

    • @Blackwido88
      @Blackwido88 6 ปีที่แล้ว

      Wendy's World look up Dr Joel Wallach on Alzheimer's disease. Its caused by using statin drugs that reduce cholesterol. Myelin is mostly cholesterol. Dr. Wallach knows how to help your mom.

    • @noleftturnunstoned
      @noleftturnunstoned 6 ปีที่แล้ว

      Alzheimer's is not caused by demyelination. That is the easiest way I can explain that to you.

  • @olaabdallah3607
    @olaabdallah3607 หลายเดือนก่อน

    Amazing explanation. You made this easy and clear. Thank you ❤❤

  • @dragonmares59110
    @dragonmares59110 7 ปีที่แล้ว +4

    Another great video !
    It was nice to see that the electrical vocabulary was used correctly too.

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว

      Thanks for your kind words!

  • @clairehenzel9975
    @clairehenzel9975 5 ปีที่แล้ว

    Amazing explanation

  • @kaushalkafle3609
    @kaushalkafle3609 6 ปีที่แล้ว +8

    I am also a ms patient : thanks for this educational video

    • @WalkofLifewithSumit
      @WalkofLifewithSumit 3 ปีที่แล้ว

      I have MS too. This has inspired me to start my owm TH-cam journey. Please check out and support.

  • @virtue1495
    @virtue1495 11 หลายเดือนก่อน

    Thank you. Very informative🙏🏾💗

  • @tony-gy2bq
    @tony-gy2bq ปีที่แล้ว

    Good video, very informative.

  • @tracytownley5130
    @tracytownley5130 4 ปีที่แล้ว +1

    very well explained - no one has ever explained this to me - i have secondary MS and was diagnosed 20 years ago

    • @Medicurio
      @Medicurio  4 ปีที่แล้ว +1

      Thank you! I'm glad to have helped and I wish you the all the best in your battle against MS.

  • @cariboowho
    @cariboowho 7 ปีที่แล้ว +32

    Keep going man. Your videos are very good, and eventually the views will come.

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว +5

      Thank you!

    • @user-angelicaddlos
      @user-angelicaddlos 4 ปีที่แล้ว

      Thanks for the video content! Apologies for the intrusion, I would appreciate your initial thoughts. Have you heard about - Liyaraah Sclerosis Redemption (should be on google have a look)? It is a great exclusive product for overcoming the symptoms of multiple sclerosis minus the headache. Ive heard some unbelievable things about it and my cousin at very last got great success with it.

    • @MariaMora31
      @MariaMora31 3 ปีที่แล้ว

      Thanks for the Video! Forgive me for chiming in, I would love your thoughts. Have you researched - Liyaraah Sclerosis Redemption (search on google)? It is a smashing exclusive guide for overcoming the symptoms of multiple sclerosis without the normal expense. Ive heard some super things about it and my m8 at last got cool success with it.

    • @thanhphongtran9808
      @thanhphongtran9808 3 ปีที่แล้ว

      Kudos for the Video! Sorry for chiming in, I would appreciate your initial thoughts. Have you heard about - Liyaraah Sclerosis Redemption (google it)? It is an awesome one of a kind product for overcoming the symptoms of multiple sclerosis minus the normal expense. Ive heard some extraordinary things about it and my friend Sam got astronomical results with it.

    • @viajedali7663
      @viajedali7663 3 ปีที่แล้ว

      33k, you were right

  • @vsatyanarayanach6664
    @vsatyanarayanach6664 3 ปีที่แล้ว

    Thank you so much

  • @mariemac5347
    @mariemac5347 5 ปีที่แล้ว

    Great! Thank you

  • @jackierubinstein548
    @jackierubinstein548 2 ปีที่แล้ว

    Amazing video! I just have one question, so the blood-brain barrier is damaged.. is there a way to repair it so that the immune cells don't have access to the brain?

  • @SantoshKumar-tr8gj
    @SantoshKumar-tr8gj 3 ปีที่แล้ว

    excellent

  • @SaadAli-qv9nf
    @SaadAli-qv9nf ปีที่แล้ว +1

    I know that Schwan cells are responsible for myelin sheath development but I have read some papers about the Oligodendrocyte Progenitor vit-D receptor cells. Is there any connection b/w them?

  • @pgraghupathi4411
    @pgraghupathi4411 4 หลายเดือนก่อน

    Good analysis for comon man

  • @darrenanimatic9675
    @darrenanimatic9675 4 ปีที่แล้ว +2

    Hey yo, can u make more videos?

  • @ernestk522
    @ernestk522 2 ปีที่แล้ว

    3:43 to 4:17 made it easier to understand but still the whole video was great

  • @samyan_saleem4252
    @samyan_saleem4252 3 ปีที่แล้ว

    Thnx

  • @eien7228
    @eien7228 3 ปีที่แล้ว

    sir where is the potassium gate in myelinated axons?

  • @sajidkhanmahmood
    @sajidkhanmahmood 4 ปีที่แล้ว +1

    will B12 supplementation help to prevent

    • @Medicurio
      @Medicurio  4 ปีที่แล้ว +1

      According to the National MS Society, B12 deficiency can mimic multiple sclerosis symptoms, and some people with MS also have B12 deficiency, but a causal link has yet to be established. If a patient has B12 deficiency, supplementation is recommended, but there is no evidence that B12 supplementation with normal B12 levels does anything to treat/prevent MS.
      Reference: Bowling, A. Vitamins, minerals, and herbs in MS - an introduction. National MS Society, 2018

  • @spazmatt3000
    @spazmatt3000 6 ปีที่แล้ว +1

    I'd really like you to explain what different drugs and smoking Tabaco effects on the brain and body, different adhd and psychological medications on the brain and body. I'd literally promote your videos till the day I die, I'd even offer my self to help in any way lol

    • @spazmatt3000
      @spazmatt3000 6 ปีที่แล้ว

      Your very good at explaining everything and you seem like you actually understand what's what

  • @Orthodox.777
    @Orthodox.777 4 ปีที่แล้ว +2

    5:30 😂😂😂 i was laughing lol!

    • @ajsassy788
      @ajsassy788 4 ปีที่แล้ว

      Why? Nothing funny about any of this.🤬

  • @nero91
    @nero91 7 ปีที่แล้ว

    Great video again, keep em coming, but how about some background music? Nothing fancy or intruding, just simple maybe.

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว +2

      Thanks for the support! The last time background music was brought up, slightly more people wanted no music, so I've kept it that way. I'll incorporate some non-intrusive background music in my next video to see if I like it better than no music.

  • @mven
    @mven 7 ปีที่แล้ว

    This really makes me wonder what would happen if we could artificially boost the speed of the signal. If we take that further than just curing MS, boosting the signal to faster than baseline.
    What would the effects of artificial "anti-MS" be? Would that even be biologically sustainable?

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว +3

      Interesting point, I've never really thought of that. From what I understand, the distances between the Nodes of Ranvier are evolutionarily adapted so that the distance are just long enough to maximize the distance the signal travels electronically (which is very fast), but short enough so that the signal doesn't dissipate before hitting the next node. Therefore, I think we are at our maximum signal speed - increasing this speed may not even be biologically possible.
      However, if we are somehow able to increase this speed, I would imagine it would increase our thought processing and reflexes immensely. Maybe induce some kind of heightened state of mind. That would be pretty awesome.

    • @mven
      @mven 7 ปีที่แล้ว

      Evolutionary biology is limited by the materials available to it, though. Could we come up with better solutions if we're not afraid to graft some modern materials science into our cells?

    • @Medicurio
      @Medicurio  7 ปีที่แล้ว

      That might be possible, but that seems to be delving into biotechnology, which I don't have too much knowledge in. What you proposed could be a cure for MS though, if it does exist.

  • @TomeRodrigo
    @TomeRodrigo 2 ปีที่แล้ว +1

    The immune system can be such a stupid thing. Organism attacking itself. I will never understand it.

  • @joseluisdiaz233
    @joseluisdiaz233 5 ปีที่แล้ว +1

    Fucking amazing, keep on man. 👌🤜

  • @GenesisGameGenie
    @GenesisGameGenie 6 ปีที่แล้ว +2

    After watching many of your videos, I've come to the conclusion: The immune system is kind of a dick sometimes.

  • @NEWSBYTES.
    @NEWSBYTES. 4 ปีที่แล้ว

    👌

  • @Sherirose1
    @Sherirose1 6 ปีที่แล้ว +1

    👐👏👏👏👏👏👏👏👏👍👍👍👌👌👌

  • @siddyboi6929
    @siddyboi6929 3 ปีที่แล้ว +4

    LOL who is here because of biology

  • @davegregory7869
    @davegregory7869 3 ปีที่แล้ว +2

    say PNS fast

  • @ranaabuobaid5577
    @ranaabuobaid5577 4 ปีที่แล้ว

    👍❤️👍❤️👍

  • @Svnfold
    @Svnfold ปีที่แล้ว +1

    This is creepy

  • @Rando-vu6hl
    @Rando-vu6hl 3 ปีที่แล้ว +1

    E