Went on the carnivore diet a year ago blood work was incredible. HDL went from 35 to 58. LDL did go up from 101 to 144, triglycerides went from 100 to 52 yet my doctors said that she wants me a cholesterol drugs, which I Declined. I am 62 and feeling better than I have in a very long time. I was in severe pain with arthritis until the carnivore diet. Now I am pain-free. It’s a miracle when you think about it, in my case anyway. Will continue with it.
My high LDL used to be a conundrum until I found the LMHR group and Dave Feldman. I think the Lipid Energy Model explains it beautifully. My LDL has run around 250 for 7 years now on a carnivore diet. I had a CAC done after year one which was a perfect zero. This year after 6 years of a high fat carnivore diet I had a CTA with CAC done. My CAC was still a perfect zero and the CTA showed no plaque in the arteries around my heart! With zero carbs consumed on a low carb/carnivore diet, your liver produces LDL as an energy source/substrate. Carnivore is the best thing that ever happened to me. Now I know that high LDL and ApoB are not a bad thing in the context of Keto/carnivore
My LDL runs about the same after being on a ketovore, almost entirely carnivore, diet seven months, but my recent CAC score was 243. That was my first time to take that test, so the high calcium score may reflect the years I spent eating a grain and vegetable heavy diet with only a few servings a meat per week. Now I will have to wait until I can talk my doctor into ordering another CAC to compare how this diet is impacting it going forward.
@@okiebasiltry getting a PET scan instead to look at flow. Your arteries can reform. If you have no symptoms, and the flow is normal, its likely the calcium isn't narrowing your arteries.
Can’t tell how amazed I am carnivore for almost a year at 59 years young with several cheat days a month but mostly carnivore 95% of the time BP is a steady 110/70 plus I’m at the weight I was when I did the Ironman triathlon 20 years ago without having to do all the training! In addition im extremely vascular with exceptional blood flow if you get my drift, I’m not worried about LDL at all.
@ then I would try supplementation of Vitamin D3 with Magnesium, Zinc and Berberine. Also add K2, it moves calcium caused by Vitamin D3 from arteries to bones
I can speak for myself. I have been on interval LCHF since February 2021. Since February 24, I switched to LCHPWF (6/18). The last measurement of blood cholesterol: total 410 mg/dl, HDL 90, TG 80. Doppler ultrasound shows no problems with the Intima Media complex. But when I saw an increase in total cholesterol in 2022, I signed up for liver elastometry. For two days I ate only boiled meat with a small rice amount before the study. On the day of the ultrasound, I donated blood for a lipid profile. Total cholesterol was 255 ng/dl, HDL 75, and TG 65. This shows how quickly the concentration of cholesterol in the blood changes. You don't need to pay attention to total cholesterol. The TG/HDL ratio is important. After switching to a Ketogenic diet, I have never had >1. The cardiologist says: statins are unnecessary, your heart and blood vessels are fine at 52 years old, just keep watching.
I went on a low carb diet in June when my A1c crept up to 5.8, My blood test results showed it declined to 5.6 by early October. My HDL and triglyceride were 70 and 82, respectively. All my life I struggled to get HDL above 40. My LDL was at 115 but my doctor said that was OK. I also lost about 7 pounds. Fasting glucose was at 100 which was a slight decline. I will get another metabolic and lipid panel early next year. What I’m struggling with is a sudden rise in systolic blood pressure. Used to average about 120 but is now about 135. That is what prompted to doctor visit in June so it is not a result of the low carb diet. I am of non-obese BMI, do either weights or cardio almost every day. Body fat is about 16% I am 65, so I suspect some kind of hormone change. I also started waking up to urinate once a night regularly. I thought it might be micro plastics from the Keurig coffee pods so I stopped using them. The night time urination has stopped but the blood pressure is still high. Really don’t know what other lifestyle changes I can make. I drink little alcohol, avoid processed foods make everything at home. Probably have to go on blood pressure meds.
Sorry but cholesterol is the same the vehicle maybe different (i.e. LDL, HDL) .... therefore cholesterol is not the issue. But we have drugs that reduce LDL so its obviously the problem (great for profit) and forget the facts.
Human Cholesterol Metabolism - Carbohydrates - Thyroid T3 - Vitamin-C - Fiber - Adipose Tissue - Carbohydrates Yes, the amount of carbohydrates in your diet can affect your levels of triiodothyronine (T3), the active form of thyroid hormone: High-carb diets: These diets are associated with higher T3 levels. Low-carb diets: These diets can reduce the activity of the enzyme that converts T4 into T3, resulting in lower T3 levels. Fasting: Prolonged fasting or calorie restriction can reduce T3 production When you drastically reduce or eliminate carbohydrates from your diet, your T3 thyroid hormone levels can decrease, as carbohydrates play a crucial role in the conversion of T4 (inactive thyroid hormone) to the active T3 form, meaning a lack of carbs can potentially impair thyroid function and lead to lower T3 levels; this is particularly concerning for individuals with hypothyroidism. - Thyroid T3 Yes, thyroid hormone T3 is closely linked to cholesterol levels: Underactive thyroid (hypothyroidism) When the thyroid doesn't produce enough T3, the liver can't process and remove excess cholesterol from the body. This can lead to high levels of LDL and total cholesterol. T3, the active form of thyroid hormone, plays a significant role in regulating cholesterol levels by stimulating the conversion of cholesterol into bile acids, thereby promoting the elimination of excess cholesterol from the body through bile secretion; essentially, when T3 levels are adequate, it helps the liver efficiently process and remove cholesterol by increasing bile acid production and excretion. - Vitamin-C Vitamin C is involved in regulating cholesterol metabolism and the production of bile acids: Vitamin C is necessary for the transformation of cholesterol into bile acids. The liver's rate of cholesterol to bile acid conversion is reduced in animals with vitamin C deficiency. This can lead to cholesterol accumulating in the liver and blood serum. A deficiency in vitamin C can indirectly lower cholesterol absorption. This is due to a reduction in the availability of bile acids, monoglycerides, and fatty acids Humans and other primates, like apes, are unable to synthesize vitamin C because of a mutation in the gene for gulonolactone oxidase, the enzyme that's needed to produce - Fiber Dietary fiber, particularly soluble fiber, can lower cholesterol levels by binding to bile acids in the intestines, preventing their reabsorption back into the bloodstream and ultimately leading to their excretion from the body, thus reducing the amount of cholesterol that can be absorbed from food; this process is key to the cholesterol-lowering effect of fiber-rich diets. - Adipose Tissue Adipose tissue, or fat tissue, is a major storage site for cholesterol in the body. In fact, more than half of the body's cholesterol can be stored in adipose tissue in people who are obese
"The only way to produce atherosclerosis in a carnivore is to take out the thyroid gland; then, for some reason, saturated fat and cholesterol have the same effect as in herbivores." "Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.[1]" "Thyroid Disease and the Heart" "Review of multiple cross-sectional studies demonstrates that ≈30% of patients with congestive heart failure have low T3 levels. The decrease in serum T3 is proportional to the severity of the heart disease as assessed by the New York Heart Association functional classification" "Reduced serum T3 is a strong predictor of all-cause and cardiovascular mortality and, in fact, is a stronger predictor than age, left ventricular ejection fraction, or dyslipidemia" "Thyroid Dysfunction and Atherosclerosis: A Systematic Review" "Hypothyroidism and subclinical hypothyroidism (SH), which is characterized by elevated thyroid stimulating hormone (TSH) levels and normal circulating free thyroid hormones, are independent risk factors for the pathogenesis of atherosclerosis and cardiovascular disease, affecting adversely the endothelial function (1-3). More specifically, they are correlated with i) high levels of low-density-lipoprotein cholesterol (LDL), ii) abnormal diastolic blood pressure, iii) low-grade inflammation and iv) hypercoagulability (4)." "Besides affecting cardiovascular risk factors, longstanding mild thyroid hormone deficiency can lead to structural changes in the arterial wall." "Evidence from in vitro and animal model studies have demonstrated a remarkable effect of thyroid hormones to fibroblasts, especially in regards to collagen type I expression." "Thyroid function influences serum apolipoprotein B-48 levels in patients with thyroid disease" "Conclusion: Increased serum apoB-48 concentrations and CMR may contribute to the increased risk of atherosclerosis and premature coronary artery disease in the hypothyroid state" "Thyroid hormones and coronary artery calcification in euthyroid men and women" "In a large cohort of apparently healthy young and middle-aged euthyroid men and women, low-normal free thyroxin and thyroid-stimulating hormone were associated with a higher prevalence of subclinical coronary artery disease and with a greater degree of coronary calcification." "Triiodothyronine (T3) therapy can rapidly lower plasma lipoprotein(a) (Lp(a)) levels in patients with hypothyroidism. This is because thyroid hormone regulates plasma Lp(a) and apo-B in a parallel manner" "Hypothyroidism is associated with increased levels of Lp(a), which can increase the risk of cardiovascular disease. This is because hypothyroidism also increases levels of other lipid profile markers, such as total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol"
"An Amazon-based Bolivian tribe called the Tsimane may hold the secret to perfect health and longevity for their 16,000 members, according to new research published in the Journals of Gerontology. For two decades, researchers have sought to understand why this indigenous tribe has lived almost completely free of heart disease, obesity, diabetes, and age-related cognitive decline." "Indigenous South American group has healthiest arteries of all populations yet studied" "An 80-year-old from the Tsimane (pronounced chee-MAH-nay) group had the same vascular age as an American in his or her mid-fifties" 'World's Healthiest Arteries' Found to Be the Most Elastic "These arteries recently were found to be exceptionally elastic and to age more gradually, according to a study presented at the 2023 Annual Congress of the American Heart Association in Philadelphia." "Some of the world's lowest rates of dementia found in Amazonian indigenous group" "A new study reveals that two indigenous groups in the Bolivian Amazon have among the lowest rates of dementia in the world" "Their diet is largely carbohydrate-based (72%) and includes non-processed carbohydrates which are high in fibre such as rice, plantain, manioc, corn, nuts and fruits. Protein constitutes 14% of their diet. The diet is very low in fat with fat compromising only 14% of the diet -- equivalent to an estimated 38 grams of fat each day, including 11g saturated fat and no trans fats." "The Tsimane diet is most like the Okinawa diet, named after the island in Japan whose inhabitants have some of the highest life expectancies in the world. Okinawans eat a lot of rice and purple sweet potato and limit their consumption of meat, seafood and dairy to small amounts. Both diets focus on complex, not refined, carbohydrates." "According to research, the Tsimane people, an indigenous population in Bolivia, have exceptionally low LDL cholesterol levels, averaging around 72mg/dL"
My doctor prescribed a statin because I had slightly elevated LDL , mid normal range Cholesterol , HDL, Total C/HDL, non HDL. I will ask for APOB/APOA ratio and (lipoprotein a) tests next visit. Nobody will ever tell me I can stop taking the statin. That decision will have to be mine alone.
Went on the carnivore diet a year ago blood work was incredible. HDL went from 35 to 58. LDL did go up from 101 to 144, triglycerides went from 100 to 52 yet my doctors said that she wants me a cholesterol drugs, which I Declined. I am 62 and feeling better than I have in a very long time. I was in severe pain with arthritis until the carnivore diet. Now I am pain-free. It’s a miracle when you think about it, in my case anyway. Will continue with it.
Your story mirrors mine exactly. I politely declined to be out on statins. Statins scare the hell out of me. Just look at the potential side effects.
LDL of 144 is nothing. Mine is 328.
My numbers did almost the same. HDL now higher than TGL whereas my TGL used to be 3-4 times higher than my HDL. Feeling great.
Cholesterol is good for you. Being a Carnivore my HDL was 129, LDL 440. I just ate a 2 pound Tomahawk Steak. I am stuffed.
LDL-C of 440 mg/dl will cause your heart disease to get worse
My high LDL used to be a conundrum until I found the LMHR group and Dave Feldman. I think the Lipid Energy Model explains it beautifully. My LDL has run around 250 for 7 years now on a carnivore diet. I had a CAC done after year one which was a perfect zero. This year after 6 years of a high fat carnivore diet I had a CTA with CAC done. My CAC was still a perfect zero and the CTA showed no plaque in the arteries around my heart! With zero carbs consumed on a low carb/carnivore diet, your liver produces LDL as an energy source/substrate. Carnivore is the best thing that ever happened to me. Now I know that high LDL and ApoB are not a bad thing in the context of Keto/carnivore
My LDL runs about the same after being on a ketovore, almost entirely carnivore, diet seven months, but my recent CAC score was 243. That was my first time to take that test, so the high calcium score may reflect the years I spent eating a grain and vegetable heavy diet with only a few servings a meat per week. Now I will have to wait until I can talk my doctor into ordering another CAC to compare how this diet is impacting it going forward.
@@okiebasiltry getting a PET scan instead to look at flow. Your arteries can reform. If you have no symptoms, and the flow is normal, its likely the calcium isn't narrowing your arteries.
Love the truth you've been puttin out, especially around this topic. Keep it up!
Can’t tell how amazed I am carnivore for almost a year at 59 years young with several cheat days a month but mostly carnivore 95% of the time BP is a steady 110/70 plus I’m at the weight I was when I did the Ironman triathlon 20 years ago without having to do all the training! In addition im extremely vascular with exceptional blood flow if you get my drift, I’m not worried about LDL at all.
On the Carnivore diet, blood pressure lowered to an average of 125/73 from 139/89. I feel much better as well.
My blood pressure is the only thing that has not improved from a low carb diet.
@ then I would try supplementation of Vitamin D3 with Magnesium, Zinc and Berberine. Also add K2, it moves calcium caused by Vitamin D3 from arteries to bones
Magnesium (supplemental) and potassium (food) makes a huge difference to BP.
What did your ApoB do?
I’m 66 ldl hdl both went up after I turned carnivore tris went down and I feel fantastic hdl was 109 tris were 69 ldl was 365 love my lipid panel 👍😊
Spain. High sun exposure.
Adn Finland quite the reverse
First and foremost, I want to know who funded ANY study I aee.
I can speak for myself. I have been on interval LCHF since February 2021. Since February 24, I switched to LCHPWF (6/18). The last measurement of blood cholesterol: total 410 mg/dl, HDL 90, TG 80. Doppler ultrasound shows no problems with the Intima Media complex. But when I saw an increase in total cholesterol in 2022, I signed up for liver elastometry. For two days I ate only boiled meat with a small rice amount before the study. On the day of the ultrasound, I donated blood for a lipid profile. Total cholesterol was 255 ng/dl, HDL 75, and TG 65. This shows how quickly the concentration of cholesterol in the blood changes. You don't need to pay attention to total cholesterol. The TG/HDL ratio is important. After switching to a Ketogenic diet, I have never had >1. The cardiologist says: statins are unnecessary, your heart and blood vessels are fine at 52 years old, just keep watching.
Low GI carb group results look pretty good. I wonder how much carbs the low carb group was eating and if they were high GI or low GI.
Mike is the man
I went on a low carb diet in June when my A1c crept up to 5.8, My blood test results showed it declined to 5.6 by early October. My HDL and triglyceride were 70 and 82, respectively. All my life I struggled to get HDL above 40. My LDL was at 115 but my doctor said that was OK. I also lost about 7 pounds. Fasting glucose was at 100 which was a slight decline. I will get another metabolic and lipid panel early next year.
What I’m struggling with is a sudden rise in systolic blood pressure. Used to average about 120 but is now about 135. That is what prompted to doctor visit in June so it is not a result of the low carb diet. I am of non-obese BMI, do either weights or cardio almost every day. Body fat is about 16% I am 65, so I suspect some kind of hormone change. I also started waking up to urinate once a night regularly. I thought it might be micro plastics from the Keurig coffee pods so I stopped using them. The night time urination has stopped but the blood pressure is still high. Really don’t know what other lifestyle changes I can make. I drink little alcohol, avoid processed foods make everything at home. Probably have to go on blood pressure meds.
Hey are you using mouthwash? That is known to increase your blood pressure.
@@iss8504 - Yes but I’ve used the same alcohol and flouride free mouthwash for years when my BO was 120/65
What would you replace LDL with as a higher-is-bad marker? ApoB? Or could you measure small, dense, damaged/oxidized LDL level?
I just got health insurance. Gonna get some basic bloodwork for the first time in 14 years.
You just mention LDL as a whole. What about big fluffy vs small density ldl particles?
LDL if far more associated to CVD risk than HDL
What do you think of Dana White's triglycerides of 764?
a long way to say the old rule that we need to lower the ratio of total cholesterol to ldl
Nice camera(s)
Sorry but cholesterol is the same the vehicle maybe different (i.e. LDL, HDL) .... therefore cholesterol is not the issue. But we have drugs that reduce LDL so its obviously the problem (great for profit) and forget the facts.
Human Cholesterol Metabolism
- Carbohydrates
- Thyroid T3
- Vitamin-C
- Fiber
- Adipose Tissue
- Carbohydrates
Yes, the amount of carbohydrates in your diet can affect your levels of triiodothyronine (T3), the active form of thyroid hormone:
High-carb diets: These diets are associated with higher T3 levels.
Low-carb diets: These diets can reduce the activity of the enzyme that converts T4 into T3, resulting in lower T3 levels.
Fasting: Prolonged fasting or calorie restriction can reduce T3 production
When you drastically reduce or eliminate carbohydrates from your diet, your T3 thyroid hormone levels can decrease, as carbohydrates play a crucial role in the conversion of T4 (inactive thyroid hormone) to the active T3 form, meaning a lack of carbs can potentially impair thyroid function and lead to lower T3 levels; this is particularly concerning for individuals with hypothyroidism.
- Thyroid T3
Yes, thyroid hormone T3 is closely linked to cholesterol levels:
Underactive thyroid (hypothyroidism)
When the thyroid doesn't produce enough T3, the liver can't process and remove excess cholesterol from the body. This can lead to high levels of LDL and total cholesterol.
T3, the active form of thyroid hormone, plays a significant role in regulating cholesterol levels by stimulating the conversion of cholesterol into bile acids, thereby promoting the elimination of excess cholesterol from the body through bile secretion; essentially, when T3 levels are adequate, it helps the liver efficiently process and remove cholesterol by increasing bile acid production and excretion.
- Vitamin-C
Vitamin C is involved in regulating cholesterol metabolism and the production of bile acids:
Vitamin C is necessary for the transformation of cholesterol into bile acids. The liver's rate of cholesterol to bile acid conversion is reduced in animals with vitamin C deficiency. This can lead to cholesterol accumulating in the liver and blood serum.
A deficiency in vitamin C can indirectly lower cholesterol absorption. This is due to a reduction in the availability of bile acids, monoglycerides, and fatty acids
Humans and other primates, like apes, are unable to synthesize vitamin C because of a mutation in the gene for gulonolactone oxidase, the enzyme that's needed to produce
- Fiber
Dietary fiber, particularly soluble fiber, can lower cholesterol levels by binding to bile acids in the intestines, preventing their reabsorption back into the bloodstream and ultimately leading to their excretion from the body, thus reducing the amount of cholesterol that can be absorbed from food; this process is key to the cholesterol-lowering effect of fiber-rich diets.
- Adipose Tissue
Adipose tissue, or fat tissue, is a major storage site for cholesterol in the body. In fact, more than half of the body's cholesterol can be stored in adipose tissue in people who are obese
"The only way to produce atherosclerosis in a carnivore is to take out the thyroid gland; then, for some reason, saturated fat and cholesterol have the same effect as in herbivores."
"Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.[1]"
"Thyroid Disease and the Heart"
"Review of multiple cross-sectional studies demonstrates that ≈30% of patients with congestive heart failure have low T3 levels. The decrease in serum T3 is proportional to the severity of the heart disease as assessed by the New York Heart Association functional classification"
"Reduced serum T3 is a strong predictor of all-cause and cardiovascular mortality and, in fact, is a stronger predictor than age, left ventricular ejection fraction, or dyslipidemia"
"Thyroid Dysfunction and Atherosclerosis: A Systematic Review"
"Hypothyroidism and subclinical hypothyroidism (SH), which is characterized by elevated thyroid stimulating hormone (TSH) levels and normal circulating free thyroid hormones, are independent risk factors for the pathogenesis of atherosclerosis and cardiovascular disease, affecting adversely the endothelial function (1-3). More specifically, they are correlated with i) high levels of low-density-lipoprotein cholesterol (LDL), ii) abnormal diastolic blood pressure, iii) low-grade inflammation and iv) hypercoagulability (4)."
"Besides affecting cardiovascular risk factors, longstanding mild thyroid hormone deficiency can lead to structural changes in the arterial wall."
"Evidence from in vitro and animal model studies have demonstrated a remarkable effect of thyroid hormones to fibroblasts, especially in regards to collagen type I expression."
"Thyroid function influences serum apolipoprotein B-48 levels in patients with thyroid disease"
"Conclusion: Increased serum apoB-48 concentrations and CMR may contribute to the increased risk of atherosclerosis and premature coronary artery disease in the hypothyroid state"
"Thyroid hormones and coronary artery calcification in euthyroid men and women"
"In a large cohort of apparently healthy young and middle-aged euthyroid men and women, low-normal free thyroxin and thyroid-stimulating hormone were associated with a higher prevalence of subclinical coronary artery disease and with a greater degree of coronary calcification."
"Triiodothyronine (T3) therapy can rapidly lower plasma lipoprotein(a) (Lp(a)) levels in patients with hypothyroidism. This is because thyroid hormone regulates plasma Lp(a) and apo-B in a parallel manner"
"Hypothyroidism is associated with increased levels of Lp(a), which can increase the risk of cardiovascular disease. This is because hypothyroidism also increases levels of other lipid profile markers, such as total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol"
"An Amazon-based Bolivian tribe called the Tsimane may hold the secret to perfect health and longevity for their 16,000 members, according to new research published in the Journals of Gerontology. For two decades, researchers have sought to understand why this indigenous tribe has lived almost completely free of heart disease, obesity, diabetes, and age-related cognitive decline."
"Indigenous South American group has healthiest arteries of all populations yet studied"
"An 80-year-old from the Tsimane (pronounced chee-MAH-nay) group had the same vascular age as an American in his or her mid-fifties"
'World's Healthiest Arteries' Found to Be the Most Elastic
"These arteries recently were found to be exceptionally elastic and to age more gradually, according to a study presented at the 2023 Annual Congress of the American Heart Association in Philadelphia."
"Some of the world's lowest rates of dementia found in Amazonian indigenous group"
"A new study reveals that two indigenous groups in the Bolivian Amazon have among the lowest rates of dementia in the world"
"Their diet is largely carbohydrate-based (72%) and includes non-processed carbohydrates which are high in fibre such as rice, plantain, manioc, corn, nuts and fruits. Protein constitutes 14% of their diet. The diet is very low in fat with fat compromising only 14% of the diet -- equivalent to an estimated 38 grams of fat each day, including 11g saturated fat and no trans fats."
"The Tsimane diet is most like the Okinawa diet, named after the island in Japan whose inhabitants have some of the highest life expectancies in the world. Okinawans eat a lot of rice and purple sweet potato and limit their consumption of meat, seafood and dairy to small amounts. Both diets focus on complex, not refined, carbohydrates."
"According to research, the Tsimane people, an indigenous population in Bolivia, have exceptionally low LDL cholesterol levels, averaging around 72mg/dL"
🤷♂IDK, but hypothyroidism and hypercholesterolemia does to appear to be "High Intensity Health".
My doctor prescribed a statin because I had slightly elevated LDL , mid normal range Cholesterol , HDL, Total C/HDL, non HDL.
I will ask for APOB/APOA ratio and (lipoprotein a) tests next visit. Nobody will ever tell me I can stop taking the statin. That decision will have to be mine alone.
Well... I mean it's normal if it isn't being converted into hormones as it should be..
I’ll volunteer for the high glycemic diet.