The Limit of Detection

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  • เผยแพร่เมื่อ 2 ม.ค. 2025

ความคิดเห็น • 6

  • @tjgolaso
    @tjgolaso 3 ปีที่แล้ว

    The only thing I wonder is why 3? Is it just a number that just seems to consistently work well to determine a good S/N?

    • @shortchemistry7927
      @shortchemistry7927  3 ปีที่แล้ว +3

      Noise can be assumed to be random, and follow a standard normal distribution (bell shaped curve). A signal to noise of 3 means 3 standard deviations above the mean (baseline). A random spike in the baseline with S/N above 3 only happens about 5% of the time. So basically, it's a way of picking how sure you want to be that your signal is real, based on 95% confidence.

  • @wirtsleg
    @wirtsleg 4 ปีที่แล้ว

    This was a wonderful explanation that I haven't been able to find anywhere else. In what literature may I read more about this issue? In my current statistical book it barely touches the subject.

    • @shortchemistry7927
      @shortchemistry7927  4 ปีที่แล้ว +2

      My colleagues and I actually wrote a textbook, that is entirely FREE for you to download. Google the Trace Analysis Research Center Dalhousie University. Click the education link to download a copy of "An Introduction to Analytical Chemistry"

  • @StiffBarsBentMinds
    @StiffBarsBentMinds 2 ปีที่แล้ว +1

    standard error and SD are not the same!

  • @petermyintzaw
    @petermyintzaw 4 ปีที่แล้ว

    Thank you awesome