Calcium Channel Blockers | Mechanism of Action, Indications, Adverse Reactions, Contraindications

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  • เผยแพร่เมื่อ 16 ธ.ค. 2024

ความคิดเห็น • 173

  • @Rvns556
    @Rvns556 3 ปีที่แล้ว +16

    10:30 that giggle when you know something is very complex in medicine but you just love it so much.
    Truly Nerding Out.

  • @shahabalam3348
    @shahabalam3348 2 ปีที่แล้ว +32

    You deserve awards for teaching so nicely and amazingly ❤️

  • @TheOneAngelina
    @TheOneAngelina 3 ปีที่แล้ว +10

    Thank you! I have a Medicinal chemistry/pharmacology exam on Acei/ARBs/CCBs, RAAS, diuretics, vasodilators, sympatholytics, and dyslipidemia coming up and your videos are EXCELLENT supplementation to the lecture materials I have. I LOVE watching your videos after each lecture to really get a visual of what's going on. Keep doing what you do! Thanks guys!

  • @i-wei5328
    @i-wei5328 ปีที่แล้ว

    Beautifully explained. Thank you Professor

  • @marianamutuku6896
    @marianamutuku6896 10 หลายเดือนก่อน +8

    Here in 2024. Really helpful 😊.

  • @alejandrasaucedo7035
    @alejandrasaucedo7035 4 ปีที่แล้ว +6

    i was a nursing student (LPN) when i discovered your channel , you made my nursing journey so much easier and for that i’m eternally grateful ... i want to see you around while i do my LVN to RN program ... don’t go anywhere !

  • @griselgaspar6904
    @griselgaspar6904 4 ปีที่แล้ว +12

    You did it again Zach!! Thank you so much for all you do!

  • @TLKK2020
    @TLKK2020 4 ปีที่แล้ว +4

    I also just shared with my entire nursing school!!! Hope it gets you guys many more views you deserve it!

  • @_ms.b_
    @_ms.b_ ปีที่แล้ว +1

    Omg. You are so great. Thank you. Just started amlodipine. Ankle starting to swell.

  • @toyajohnson7221
    @toyajohnson7221 4 ปีที่แล้ว +6

    That was amazing!!! I love the way you break it down so easily.....I really understand it now and I’m excited about that. Thank you so much!

  • @muskandeshwal9299
    @muskandeshwal9299 4 ปีที่แล้ว +2

    A big big thankyou from all my heart......i wish you success ......hope you grow and reach the skies.....❤️❤️

  • @mariamhussien6303
    @mariamhussien6303 4 ปีที่แล้ว +4

    Thank you 💞 best TH-cam channel ever

  • @brianwilkerson2513
    @brianwilkerson2513 4 ปีที่แล้ว +4

    Love the videos about med. These are amazingly helpful for advanced pharmacology. Thank you for making these.

  • @pedropedretti2071
    @pedropedretti2071 2 ปีที่แล้ว +1

    Your classes are extremely helpful. Much thanks!!

  • @neelhinsu7971
    @neelhinsu7971 4 ปีที่แล้ว +40

    Please!! Make some more videos on pharmacology. It's a heartly request to you 🙏🙏😥

  • @kellyann4421
    @kellyann4421 3 ปีที่แล้ว +32

    "Make it thiccc" "That gut aint gunn work" LOL you're awesome

  • @marielouise966
    @marielouise966 3 ปีที่แล้ว +4

    im so glad that i found this lecture Ninja Nerd, since i take calcium channel blocker Lercanidipin which you didn't mention but can i assume is also acting like the other *dipines ? i have a low serum calcium and one thing i would like to know is if taking a calcium channel blocker has any affect on serum calcium levels ?

  • @aditiadvilkar2000
    @aditiadvilkar2000 4 ปีที่แล้ว +7

    The pain from cluster headaches is caused by the dilation, or widening, of the blood vessels that supply blood to your brain and face. This dilation applies pressure to the trigeminal nerve, which transmits sensations from the face to the brain. If that is the case, how do the calcium channel blockers help in relieving the cluster headaches since they cause vasodilation?

  • @sydneylimarez2816
    @sydneylimarez2816 2 ปีที่แล้ว

    Thank you! You're a life saver for medical student like me

  • @ahmadmusawer9392
    @ahmadmusawer9392 4 ปีที่แล้ว +1

    Man, you're TOP NOTCH.

  • @sebastianflorezmed
    @sebastianflorezmed ปีที่แล้ว

    I swear that I will give you my first pay as a doctor. Thank you so much Zach

  • @gk_filer
    @gk_filer 7 หลายเดือนก่อน

    I hope they pay you well. Amazing recall of complex concepts.

  • @mingukkie4746
    @mingukkie4746 ปีที่แล้ว +1

    you deserve a nobel prize

  • @deborahbollyn897
    @deborahbollyn897 ปีที่แล้ว +1

    Thanks you so much for your GREAT lectures! 👏🏼🤓👌🏼
    I have Prinzmetal’s angina a.k.a. coronary artery spasm a.k.a. CAS.
    Also referred to as ANOCA or INOCA and worse case MINOCA.
    After a Non-STEMI last year, I finally got diagnosed and since then I learned a lot from you.
    Thank you very much! 🙏🏼

  • @mapenzihamoomba8749
    @mapenzihamoomba8749 3 ปีที่แล้ว

    Always enjoy these videos on pharmacology😃🙌

  • @ariyotolulope1360
    @ariyotolulope1360 4 ปีที่แล้ว +3

    Your videos are always wonderful. I which in no time you cover other aspects of pharmacology eg CNS,respiratory, endocrinology etc. Thanks alot

  • @kiruua-g4z
    @kiruua-g4z 4 ปีที่แล้ว +4

    Its amazing video. when ever i got questions or misunderstanding while studying, watching ur videos comes to mind first. I really appreciate the way you describe. keep it up please. am my question is, it might look silly but in calcium channel blocker video how constipation results as side effect? i mean i don't understand how CCBS decrease GI motility

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  4 ปีที่แล้ว +5

      Calcium is needed in smooth muscles to cause smooth muscle contraction. If you block calcium entry you block smooth muscle contraction

    • @ambissaintek5778
      @ambissaintek5778 2 ปีที่แล้ว

      can i ask some question? CCB is calcium channel blocker to vasodilate, but how can the calcium for lower blood pressure in some journal?

    • @tubaumer6356
      @tubaumer6356 ปีที่แล้ว

      ​@@ambissaintek5778by decreasing contractility when contractility decrease sv decrease co decrease and hence systolic blood pressure decrease

  • @JohnMushitu
    @JohnMushitu 4 ปีที่แล้ว +2

    Very helpful 🙌🏾 You simply the best 💪🏾

  • @SonamSherpa-ye3nf
    @SonamSherpa-ye3nf ปีที่แล้ว

    Super simplified lecture thank you soo musch

  • @afsheenilyas7532
    @afsheenilyas7532 4 ปีที่แล้ว

    I first time understanding the pharma so well..🤩

  • @talhaiqbal1660
    @talhaiqbal1660 3 ปีที่แล้ว

    Good job big brother...
    Superb presentation
    From India

  • @SirViving
    @SirViving 7 หลายเดือนก่อน

    You explained it so well 👍🏻

  • @architasaha8917
    @architasaha8917 4 ปีที่แล้ว

    You explained it in such a interesting and easy way, very much grateful to you. Thanks a lot.

  • @robertscouten8389
    @robertscouten8389 2 ปีที่แล้ว

    Bravo! Continued excellent teaching!

  • @RAAGECAGE
    @RAAGECAGE 4 ปีที่แล้ว +4

    Love the videos as a quick review! If possible, it would be nice if you could use different colors when drawing arrows for increases or decreases in mechanisms

  • @dsk_graphy343
    @dsk_graphy343 หลายเดือนก่อน

    Greatly helpful! ❤

  • @vsrump
    @vsrump 2 ปีที่แล้ว

    ⭐️⭐️⭐️⭐️⭐️fabulous !!!even gives the “antidote” at the end 👍

  • @lukefarrelly724
    @lukefarrelly724 ปีที่แล้ว

    Thanks man i really understand them now

  • @torithomas2304
    @torithomas2304 2 ปีที่แล้ว +2

    I watch your videos as if they were a Netflix series.

  • @eliasgitonga6805
    @eliasgitonga6805 22 วันที่ผ่านมา

    another superb video

  • @paracletus3166
    @paracletus3166 3 ปีที่แล้ว +1

    25:41 😂
    Man you are amazing

  • @twang2884
    @twang2884 4 ปีที่แล้ว +2

    Hey ninja need, I have a question regarding non-dihyro and dihydro. U said non dihydro slow the HR as well as contractility of heart, dihyro only affect vascular dilation. My question is: does dihydro only affect vascular system or they also affect the heart contractility? Because when I listen to ur lecture, when u talked about what indication for both type CCB, I was bit confused. Thank you

    • @sharonsililo7663
      @sharonsililo7663 4 ปีที่แล้ว +2

      Dihydros eg Amlodipine ,primarily work on the vascular system.. In my own understanding, I think they also have an effect on the heart but not to significant amounts. Hence, they are very useful in isolated diastolic hypertension and NOT isolated systolic hypertension..
      I don't know if you get my point though

  • @mohammads.jefferson7295
    @mohammads.jefferson7295 4 ปีที่แล้ว

    your vids make learning fun

  • @Joy-y31
    @Joy-y31 2 ปีที่แล้ว

    Beautiful, I got tons of useful information.

  • @bhagat3328
    @bhagat3328 4 ปีที่แล้ว

    Thank you so much for making it easier for us

  • @twesigyemayres2901
    @twesigyemayres2901 3 ปีที่แล้ว

    U are the best teacher

  • @Harir_vision_life
    @Harir_vision_life 2 ปีที่แล้ว +1

    Sir you are amazing... thank you so much

  • @niazwali8169
    @niazwali8169 4 ปีที่แล้ว

    thank u so much sir i really become very happy when i saw ur vedios continous sir cardiovascular pharmacology

  • @kellyjellyxoxo
    @kellyjellyxoxo 3 ปีที่แล้ว +1

    Hey, can you please clarify why BBs (that dec contractility, rate and vasodialate) are ok in HF but CCBs (that do the same) are not?

  • @mukilvendhan9567
    @mukilvendhan9567 2 ปีที่แล้ว

    Thank you sir. Best of the best sir.

  • @يوسفمحمدمعتوكمحمدحسن
    @يوسفمحمدمعتوكمحمدحسن 2 ปีที่แล้ว

    Thank you very much doctor ❤️

  • @simgarfu
    @simgarfu 3 ปีที่แล้ว

    Amazing stuff! I wish I had this during my NSG studying lol.

  • @jehansharif8414
    @jehansharif8414 4 ปีที่แล้ว

    Really outstanding and great lecture
    Plz keep it up fore more lecs

  • @naomifavor2887
    @naomifavor2887 3 ปีที่แล้ว

    Pretty cool,it's making sense now

  • @allymusto1130
    @allymusto1130 2 ปีที่แล้ว +1

    What are your thoughts on taking D3 and K2 while being prescribed Amlodipine 2.5 mg?

  • @perceptioniseverything648
    @perceptioniseverything648 ปีที่แล้ว

    Thank you for this. Currently on verapamil which one would you suggest to help dilate the left side jugular vein valve. That is the issue of my disease. Thank you very much

  • @mohamedelmi4172
    @mohamedelmi4172 ปีที่แล้ว

    Thanks for refreshing.

  • @youssefrefaat1594
    @youssefrefaat1594 4 ปีที่แล้ว +3

    can you make a video on anti-arrhythmic drugs?

  • @msieurdaveyray5393
    @msieurdaveyray5393 3 ปีที่แล้ว

    Great tutorial, thanks.

  • @Dr.SachinAJoshi
    @Dr.SachinAJoshi 4 ปีที่แล้ว +1

    Hi. Instead of doing so means giving Calcium with these drugs, can we give Calcium at the first step along with Vitamin D3 and K2 to flow the calcium in cells and NATURALLY MAINTAIN THE HYPERTENSION?? Please suggest.

  • @rnoqks
    @rnoqks 4 ปีที่แล้ว

    in patient with emergancy hypertension. why the Drugs is dihydrpyridine and not verampil or nondihydrodipine? they affects on Heart dirct why we used Drug affect on smoothmuscles?

  • @TLKK2020
    @TLKK2020 4 ปีที่แล้ว

    Donation just sent thank you!!!

  • @fredericolc6016
    @fredericolc6016 4 ปีที่แล้ว

    Great lesson!

  • @dhanushkalakmal7652
    @dhanushkalakmal7652 10 หลายเดือนก่อน

    Thank u so much ❤🎉

  • @thantthuhain1688
    @thantthuhain1688 2 ปีที่แล้ว

    Thank You very much.

  • @johnb3057
    @johnb3057 2 ปีที่แล้ว

    Your videos are the best! Thank you

  • @zeevberar1663
    @zeevberar1663 4 ปีที่แล้ว +1

    amazing THANKS
    TEL AVIV

  • @TLKK2020
    @TLKK2020 4 ปีที่แล้ว

    I’ll donate more once I get more money!!

  • @cnik3313
    @cnik3313 3 ปีที่แล้ว

    great video as always!!!! Question: what would happen if you gave a calcium channel blocker to a patient with a junctional tachycardia rhythm? Is that a bad idea?

  • @achalakp705
    @achalakp705 9 หลายเดือนก่อน

    Big thanks ♥️

  • @kellyramirez744
    @kellyramirez744 4 ปีที่แล้ว

    Can you clarify the fact that nifedipine is said to actually increase HR since it is dihydropyridine and diltiazem is a Non-dihydropyridine

  • @mylvalopes6045
    @mylvalopes6045 3 ปีที่แล้ว

    You are my hero!

  • @muttakimmahmud5385
    @muttakimmahmud5385 3 ปีที่แล้ว

    Please make a video about centrally acting antihypertensive drugs.

  • @NDtoker
    @NDtoker 4 ปีที่แล้ว

    could you do a video on which class of antiaarythmics to use for certain things. example my dad.is on flecanide for afib and.most patients at my hospital are put on diltalzam and only reason i can find is physcian preference

  • @cathum
    @cathum 4 ปีที่แล้ว

    Well done - thank you

  • @goldsilverthesafe-haven
    @goldsilverthesafe-haven หลายเดือนก่อน

    What is the safest calcium channel blocker?
    Which calcium channel blocker is safest? Most people do not have problems taking their calcium channel blockers, but these drugs can have side effects. Benzothiazepines (diltiazem) and phenylalkylamines (verapamil) generally have fewer side effects.
    5 of the worst blood pressure medications --------
    - Beta blockers. Usually, beta blockers aren't used as first-choice therapies to lower blood pressure.
    - Loop diuretics. Furosemide (Lasix) is a type of diuretic (water pill) known as a loop diuretic.
    - Alpha blockers.
    - Vasodilators.
    - Alpha-2 agonists.
    What is a natural calcium channel blocker?
    Magnesium is a natural calcium channel blocker, blocks sodium attachment to vascular smooth muscle cells, increases vasodilating PGE, binds potassium in a cooperative manner, increases nitric oxide, improves endothelial dysfunction, causes vasodilation, and reduces blood pressure.

  • @greenottri1783
    @greenottri1783 4 ปีที่แล้ว

    Thank you Zack

  • @studysongz19
    @studysongz19 4 ปีที่แล้ว

    Awesome video! Another great one! Just dropped a skull anatomy song yesterday.

  • @sujatakumari8052
    @sujatakumari8052 4 ปีที่แล้ว

    Amazing video thank u....... zach

  • @nicolegalloway6215
    @nicolegalloway6215 11 หลายเดือนก่อน

    Do you have printable concept pages?

  • @xaviersuv791
    @xaviersuv791 4 ปีที่แล้ว +4

    I wish he had a worksheet or something to go along with the lesson.

  • @anilkumarjangbahadu229
    @anilkumarjangbahadu229 3 ปีที่แล้ว

    Sir can I use metoprolol with amlodipine to control bp and supraventricular tachycardia

  • @nilkiani7334
    @nilkiani7334 4 ปีที่แล้ว

    Well done🤓👏🏼that’s amazing

  • @fawziehsharabati7302
    @fawziehsharabati7302 2 ปีที่แล้ว

    You are great 💕💕💕

  • @nicolecoyle4750
    @nicolecoyle4750 ปีที่แล้ว

    oh my >>> you're amazing thank you!!!!!

  • @saadomoula2153
    @saadomoula2153 3 ปีที่แล้ว

    thank you so much you are the best one

  • @diannemariecalla9954
    @diannemariecalla9954 3 ปีที่แล้ว

    Thank you, Sir

  • @BigHushAffiliate
    @BigHushAffiliate 3 ปีที่แล้ว

    Is it true there is a higher mortality rate for people taking calcium channel blockers? Im taking diltiazem 30mg 2 times daily.

  • @thebackbenchers8786
    @thebackbenchers8786 4 ปีที่แล้ว

    i want that collection of markers one day...

  • @toric2719
    @toric2719 3 ปีที่แล้ว

    this is so great

  • @istreamkerala1
    @istreamkerala1 3 ปีที่แล้ว

    Awesome ❤️❤️❤️

  • @Esther.Umoren
    @Esther.Umoren 6 หลายเดือนก่อน

    I love the part he said “ that gut ain’t gonna work”😂

  • @shahiramohammadi7284
    @shahiramohammadi7284 3 ปีที่แล้ว

    Like always great

  • @ruwanichathurika8840
    @ruwanichathurika8840 3 ปีที่แล้ว

    super teaching

  • @LordPinkiePie
    @LordPinkiePie 2 ปีที่แล้ว

    26:32 the best part DUUUH THAT GUT AİNT GONNA WORK 😂😂😂

  • @sanadsofi4397
    @sanadsofi4397 4 ปีที่แล้ว

    I hope to make more lectures about autoimmune disease such as SLE and diabete

  • @fs3579
    @fs3579 2 หลายเดือนก่อน

    Does it hinder calcium from going into brain cells causing memory problems over long term use???

  • @ФранцискаЛенаБюхер
    @ФранцискаЛенаБюхер 3 ปีที่แล้ว

    You are my hero

  • @mohamedxaaji1598
    @mohamedxaaji1598 4 ปีที่แล้ว +2

    Pleaase enter accumilation of proteins and lipoproteins and cholesterol and glycogen

  • @a30s
    @a30s 4 ปีที่แล้ว

    please make a video on larynx and pharynx in detail