Thank you for voicing up "WHAT TO DO's & WHAT TO DON'T's as precautionary measures against the virulent covid-19. My personal thank you to all of you teaming up together and spreading the basic info as we gear up to keep on finding amicable solutions and be part of the solutions to aggressively combat the danger of that virus.
Regarding the issue raised by Steph at the 18:31 mark, "why there's such a differential immune response between people", in the following medical video Dr. Klioze addresses a similar issue, namely, why people have different clinical outcomes. His essential premise is that "3 dominant factors probably determine the clinical response to SARS-CoV2 infection": th-cam.com/video/W1k1sUoLPlA/w-d-xo.html What do you think of Dr. Klioze's explanation? A brief summary of the "3 dominant factors" that Dr. Klioze proposes are: 1. "Initial viral load" 2. Immune system integrity (dynamic health & strength of one's immune system) 3. "Number and configuration of the ACE-2 metalloprotein" (the "door" through which SARS-CoV2 enters the cell)/"the ACE2 surface protein and its relationship to the Renin-Angiotensin System" Regarding the immune system & ACE2, Dr. Klioze indicates that people who have weak immune systems actually have more ACE2 receptors compared to those who are healthy and have strong immune systems. In turn, this gives the virus more opportunities to enter cells, multiply and spread through the body. Regarding viral load & ACE2, if the initial viral load is very large, then that will provide more opportunities for the virus to find ACE2 receptors, enter cells & spread. Accordingly, the combination of a weak immune system and large viral load will provide the most opportunities for the virus to find ACE2 receptors, enter cells & spread. Of course, the immune system & body are very complex & dynamic, so there could be other factors, but these are the 3 main ones proposed by Dr. Klioze. I'm not certain if this is the exact issue that Steph was raising when she wondered, "why there's such a differential immune response between people", but when it comes to SARS-CoV2 or any potential illness-inducing virus it seems that one of the most important things to know is how to protect ourselves from becoming ill/how to make ourselves less susceptible to illness. (Perhaps, the only other issue that is as important is: how can those who are severely ill be healed?) If Dr. Klioze's premise is correct, then we can do a lot of practical things to help protect ourselves, which, of course, has huge implications for individuals, communities and nations. For a more thorough explanation of "3 dominant factors [that] probably determine the clinical response to SARS-CoV2 infection" (or why some people are more susceptible to illness than others), go to: th-cam.com/video/W1k1sUoLPlA/w-d-xo.html For the entire video: th-cam.com/video/W1k1sUoLPlA/w-d-xo.html (13 minutes 19 seconds long)
These videos are engaging and addictive. ***could you please do one soon that unpacks the WHO statement about asymptomatic transmission being rare? Given ambiguity between subtle,atypical or mild symptoms and total lack of symptoms, I feel like there’s a lot to be said here.
Perfect timing Vince, just in the mood for a podcast hearing about those little kiddies of the myeloblasts and lymphoblasts leaving the marrow stroma and protecting us from viruses, the kind that make us sick. :)
1:08:38 We have known about this virus for 17 years. Is not the virology barely distinguishable from SARS-CoV-1? 380 amino acid substitutions amongst the genomic total of 29,800.
Just think.. People that can't explain the Science behind gasoline octane usage in the most basic of terms have strong opinions about COViD-19. FASCINATING!!!👍😷👍
Thank you for voicing up "WHAT TO DO's & WHAT TO DON'T's as precautionary measures against the virulent covid-19. My personal thank you to all of you teaming up together and spreading the basic info as we gear up to keep on finding amicable solutions and be part of the solutions to aggressively combat the danger of that virus.
Regarding the issue raised by Steph at the 18:31 mark, "why there's such a differential immune response between people", in the following medical video Dr. Klioze addresses a similar issue, namely, why people have different clinical outcomes.
His essential premise is that "3 dominant factors probably determine the clinical response to SARS-CoV2 infection": th-cam.com/video/W1k1sUoLPlA/w-d-xo.html
What do you think of Dr. Klioze's explanation?
A brief summary of the "3 dominant factors" that Dr. Klioze proposes are:
1. "Initial viral load"
2. Immune system integrity (dynamic health & strength of one's immune system)
3. "Number and configuration of the ACE-2 metalloprotein" (the "door" through which SARS-CoV2 enters the cell)/"the ACE2 surface protein and its relationship to the Renin-Angiotensin System"
Regarding the immune system & ACE2, Dr. Klioze indicates that people who have weak immune systems actually have more ACE2 receptors compared to those who are healthy and have strong immune systems. In turn, this gives the virus more opportunities to enter cells, multiply and spread through the body.
Regarding viral load & ACE2, if the initial viral load is very large, then that will provide more opportunities for the virus to find ACE2 receptors, enter cells & spread. Accordingly, the combination of a weak immune system and large viral load will provide the most opportunities for the virus to find ACE2 receptors, enter cells & spread.
Of course, the immune system & body are very complex & dynamic, so there could be other factors, but these are the 3 main ones proposed by Dr. Klioze.
I'm not certain if this is the exact issue that Steph was raising when she wondered, "why there's such a differential immune response between people", but when it comes to SARS-CoV2 or any potential illness-inducing virus it seems that one of the most important things to know is how to protect ourselves from becoming ill/how to make ourselves less susceptible to illness. (Perhaps, the only other issue that is as important is: how can those who are severely ill be healed?)
If Dr. Klioze's premise is correct, then we can do a lot of practical things to help protect ourselves, which, of course, has huge implications for individuals, communities and nations.
For a more thorough explanation of "3 dominant factors [that] probably determine the clinical response to SARS-CoV2 infection" (or why some people are more susceptible to illness than others), go to: th-cam.com/video/W1k1sUoLPlA/w-d-xo.html
For the entire video: th-cam.com/video/W1k1sUoLPlA/w-d-xo.html (13 minutes 19 seconds long)
These videos are engaging and addictive.
***could you please do one soon that unpacks the WHO statement about asymptomatic transmission being rare? Given ambiguity between subtle,atypical or mild symptoms and total lack of symptoms, I feel like there’s a lot to be said here.
the dark matter of Covid....35:30... 'just because we can't measure it...."
Perfect timing Vince, just in the mood for a podcast hearing about those little kiddies of the myeloblasts and lymphoblasts leaving the marrow stroma and protecting us from viruses, the kind that make us sick. :)
31:00 - we do know about the Icelandic survey, not a single case of child passing it to a parent.... and it's not the only indicator
Hello Vincent and team, do you have lot information regarding the inflamosome and IL1 inhibition? Thank you
1:08:38 We have known about this virus for 17 years. Is not the virology barely distinguishable from SARS-CoV-1? 380 amino acid substitutions amongst the genomic total of 29,800.
Yeah that’s why it’s a NOVEL Coronavirus
Just found out that you have another pod cast this week in neuroscience... Another one to listen
Some epitop of covid19 can induce Ig with hemagglutination efect?
wooo new intro music
Just think.. People that can't explain the Science behind gasoline octane usage in the most basic of terms have strong opinions about COViD-19. FASCINATING!!!👍😷👍
If we have good immune , we will get covid 19 or not?
I feel better to wear a mask covering my mouth and the second covering nouse
I not inhale microbus from mouth when i speak
Where do you get all your patients from? See CIA Fort Detrick Bio-warfare and Human Experimentation