MCQs on Lipoprotein Metabolism

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  • เผยแพร่เมื่อ 13 ต.ค. 2024
  • Lipoproteins are complex molecules that involve several different components. They contain a central core made of triglycerides and cholesterol esters. Fatty acids that are cleaved from triglycerides can be used for energy storage or production, and cholesterol is critical for steroid synthesis, cellular membrane formation, and bile acids. Surrounding this core is a mix of phospholipids, free cholesterol, and apolipoproteins (apo). The apolipoproteins are particularly important, as they play a role in classifying the lipoprotein into one of five main classes: chylomicrons, very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) provide structure and function in lipid metabolism. The differentiation between these classes depends on the size of the molecule, its lipid content, and the type of apolipoprotein it features. HDL, colloquially known as “good cholesterol,” participates in reverse cholesterol transport, while LDL, colloquially known as “bad cholesterol,” promotes atherosclerosis.
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