Azathioprine - Pharmacology, mechanism of action, side effects,
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- เผยแพร่เมื่อ 29 ก.ย. 2024
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"Azathioprine is an immunosuppressant used in various inflammatory diseases including RA and is the preferred DMARD in SLE patient who are pregnancy. It is also used to prevent renal transplant rejection. Azathioprine is a prodrug of 6-mercaptopurine which is metabolised through different pathways. Metabolism into 6-thioguanine nucleotides is of benefit because this is where azathioprine exerts its immunosuppressive effects.
An alternative metabolic pathway of 6-Mercaptopurine is via xanthine oxidase which will form 6 thiouric acid which is non toxic and can be cleared by the body. Another alternate metabolic pathway of mercaptopurine is via thiopurine methyltransferase forming 6methyl mercaptopurine which is also non toxic and can be cleared by the body. Myelosuppression is the primary side effect and can lead to malignancy especially skin cancer and lymphoma."
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OH GOD i just realized that in my high school years i look up to your vids for exams and somehow the algorithm still remembers it when this showed up in my feeds like, right now. I'm not studying medicine, but thanks for making my high school biology class a bit bearable. Keep it coming for all future physicians out there.
Lots of love from this (almost med student, but destiny say otherwise) engineering student ❤🧡💙💚💜
Changes in hair color and texture, along with hair loss could be a side effect👍
Hey doctor gave me to treat alopecia?? How
Then
Thank you.
Nice and concise, thumbs up from a renal transplant patient who takes these meds!
6-METHYL MERCAPTOPURINE IS HEPATOXIC
tomorrow i hv an exam about azathioprine omg, now i understand the mechanism. Thank you so much T-T
Pog I’m on 125mg of Azathiopaine thanks for explaining it
Are you still on azaithropine
What application di you use in drawing this video? It just awesome
Sir make video about drugs uses and its action
And about antibiotics please sir
Thank you for your really fantasic work~ :-)
Which device you use to make such vedeos
Sir videos about genetics , carcinoma , ulcers
please make a video on cardiogenic shock!
Does azathioprine affect the acitivity of the HPA axis (cortisol levels, DHEA levels), sympathetic-adrenal-medullary system, heart activity (e.g. heart rate variability)?
.
Sir its my request please provide notes of topic with videos
Write them yourself!
Great video boss, keep it coming.
Can CBD be used while using Azathioprine?
Very nicely explained
❤️
THANK YOU for making this video. Very helpful
Could you do a video on Gestational Trophoblastic Disease?
So beautiful and very good
make a video on mechanism of multiorgan failure
Very well explained thank you!
Will this effect the liver?
best explanation ever....
will affect pregnancy?
This video is amazing !
100
Great
Concise and excellent
Love your content
hi i have a question and i need help if it shows me blood drug screen 390 ng / ml how much should 1 mg tablet contain ?????? i need heelp it is for me importaaaaaaant
Please made videos on Radiology- X-ray, MRI, CT, Sonography.....
👏🙌👏
Litro learnt about this today so the vid came at the perfect time
Kindly brief review about pneumonia, causes , symptoms and drug of choice....
It’s so obvious that most patient suffering from all this deadly diseases are been enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the disease and not a cure. I have been diagonal with COPD since 2010 until I was introduce by a friend who also narrated her story online on how she was cured of Her COPD after using DR OSEMUAHU herbal Medicine. This has made it two (2) month since I was cured from that disease . All thanks to God for using this Great herbalist to heal me. I have promise to keep telling good about DR OSEMUAHU ,his medicine comes with no side effects,dont sit back and get your life ruined by some bad virus Please fill free to share Your problems with him and don’t forget to tell him I did refer you to Him. Thanks.write him on email: dr.o.osemuahu@gmail.com Or WhatsApp: +2349053317809
He can as well render help in other diseases too.
Sir please make a video on zinner syndrome.
It’s so obvious that most patient suffering from all this deadly diseases are been enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the disease and not a cure. I have been diagonal with COPD since 2010 until I was introduce by a friend who also narrated her story online on how she was cured of Her COPD after using DR OSEMUAHU herbal Medicine. This has made it two (2) month since I was cured from that disease . All thanks to God for using this Great herbalist to heal me. I have promise to keep telling good about DR OSEMUAHU ,his medicine comes with no side effects,dont sit back and get your life ruined by some bad virus Please fill free to share Your problems with him and don’t forget to tell him I did refer you to Him. Thanks.write him on email: dr.o.osemuahu@gmail.com Or WhatsApp: +2349053317809
He can as well render help in other diseases too.
Pls explain in detail about humoral immunity and cell mediated immunity.
Sir,pls do it .I will be waiting.
It’s so obvious that most patient suffering from all this deadly diseases are been enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the disease and not a cure. I have been diagonal with COPD since 2010 until I was introduce by a friend who also narrated her story online on how she was cured of Her COPD after using DR OSEMUAHU herbal Medicine. This has made it two (2) month since I was cured from that disease . All thanks to God for using this Great herbalist to heal me. I have promise to keep telling good about DR OSEMUAHU ,his medicine comes with no side effects,dont sit back and get your life ruined by some bad virus Please fill free to share Your problems with him and don’t forget to tell him I did refer you to Him. Thanks.write him on email: dr.o.osemuahu@gmail.com Or WhatsApp: +2349053317809
He can as well render help in other diseases too.
Hello dear sir plz i need your help if you may i want your Telegram
It’s so obvious that most patient suffering from all this deadly diseases are been enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the disease and not a cure. I have been diagonal with COPD since 2010 until I was introduce by a friend who also narrated her story online on how she was cured of Her COPD after using DR OSEMUAHU herbal Medicine. This has made it two (2) month since I was cured from that disease . All thanks to God for using this Great herbalist to heal me. I have promise to keep telling good about DR OSEMUAHU ,his medicine comes with no side effects,dont sit back and get your life ruined by some bad virus Please fill free to share Your problems with him and don’t forget to tell him I did refer you to Him. Thanks.write him on email: dr.o.osemuahu@gmail.com Or WhatsApp: +2349053317809
He can as well render help in other diseases too.
@@michellethomas7479 ؟؟؟
Hii sir plz make a video on endometeriosis its treatment
@@michellethomas7479 thnk u vry much for the information u provided
@@maalisaleem1923 you’re welcome you can contact the doctor he can help you get rid of yours okay
@@michellethomas7479 Actually its agreat help