Biomarkers of Ageing l Associate Professor Sara Hägg

Watch this episode of the Healthy Longevity webinar featuring Associate Professor Sara Hägg from Karolinska Institutet. Hosted by Professor Andrea Maier, they discussed how longitudinal studies, such as those from the Swedish Twin Registry and UK Biobank, shaped our understanding of ageing pathways and helped to identify potential treatments for age-related diseases.
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[@firstlast1732]

That intro with the music was horrible

[@monnoo8221]

kind of disapointing. Just parroting Horvaths marketing gigs. No reflection on those clocks, despite there are so many "challenges". They do not have functional relevance, so why building on them? Phenoage (Levine, Horvath) being the worrst of all, using chrno age on both sides of the regression equation. DNA Methylation smears out with age and gets unspecific, some sites getting more, some much less methylated. DNA meth clocks are measuring just a stochastic process. No semantic relevance at all. Grimage works for mortalitty, but only by enforcing smoking and diabetes as covariates... surprise surprise...
And such, last but not least, such studies are a huge amount of wasted money.