How to Analyze Nucleophiles & Electrophiles to Predict EVERY ORGANIC CHEMISTRY REACTION! MCAT O-CHEM

Below is a video link that goes into more detail on Formal vs Partial Charges
• Video
Below is the video link that explains how to use pKa’s to determine if a Chemical Reaction will favor the reactants or products
• Using pKa’s to Determi...
The Most Important Principle you must Understand to get an A+ in Organic Chemistry
• The Most Important Pri...
Carbocation vs Carboanion Stability
• Carbocation vs Carbani...
Acid Strength vs Base Strength
• Acid Strength vs Base ...
Leaving Group Stability
• Leaving Group Stabilit...
Induction vs Resonance
• Induction vs Resonance...
Analyzing Nucleophile vs Electrophiles Strength
• How to Analyze Nucleop...
Melting Point, Freezing Point and Boiling Point Trends
• Melting Point vs Boili...
Introduction to Electron Orbital Hybridization (sp3, sp2, sp)
• Introduction to Electr...

[@karilynnwilson8967]

best MCAT channel out there

[@noahjohnson8389]

dude I wish I was as passionate about organic chem as you. thought you were going to cry a few times. Love the enthusiasm - video was very helpful!

[@theegress3131]

This helped SOOO MUCH please keep up the good work!!!

[@curtpiazza1688]

I love the thorough explanations! 😂 🎉 ❤

[@Dustin_-]

Thank you for the video

[@GhilledM21]

i got so tired of reading jack westin/shem for months and my eyes were kneeling over. really nice to watch videos, and to have something as clear cut as this

[@MegaBaller234]

dude.. thank you

[@nateweinstock4427]

SO HELPFUL :))

[@JamieFinan]

Really like the simplicity! However, I didn't hear you discuss steric hindrance of electrophilic reactivity (aldehydes = least hindered and most kinetically favored/strongest) or resonance stabilization of your formal charges. Thanks!

[@kingofpirates891]

wow thank you so much!

[@niloofarkh4779]

thank u very much

[@aymanamiera]

youre the bestest

[@MS-mg3lz]

In the last problem, why wouldn't the electrophile react with the carbon bound to oxygen and nitrogen? Since in that case there would be more electronegative atoms pulling charge away from the carbon.

[@Realbusinessfoundations]

thnk u u u u u u u u u uu uu

[@espanadorada7962]

Your thumbnail has them backwards…

[@sciencesimplified3890]

I’m utterly shocked I missed that, thank you!

[@harley6659]

Wouldn’t that phosphate group be sterically hindered so it wouldn’t even react or am I tripping

[@sciencesimplified3890]

Do you mean would the oxygens around the phosphate block any nucleophile from being able to react with the phosphate? If that’s what you mean then I can tell you that nucleophiles are able to reach the phosphate, and this type of reaction is very common (for example adding nucleotides to DNA and RNA, hydrolysis of ATP etc)

[@harley6659]

@@sciencesimplified3890 yes that’s what I meant. Thank you for clarifying that!

[@elenagalkina5653]

good material, but I hope you are not having a stroke

[@phrenologisto]

As a 'rule of thumb' you might consider working on losing that phrase from your vocab. Etymology aint pretty (max size of stick youre allowed to beat your wife with = width of your thumb = rule of thumb). Amazing content and cant thank you enough for sharing! By all means, use the phrase. I just know that when I found out what the og rule of thumb was, it stopped feeling right when it slipped out. hard one to lose.

[@Kencan254]

Too noisy 😊